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    • RNAvigate

      Public
      Very flexible tools for plotting and analyzing all kinds of RNA structure data
      Python
      MIT License
      01070Updated Dec 10, 2024Dec 10, 2024
    • Public repository for ShapeMapper 2 releases
      C++
      Other
      1632230Updated Dec 4, 2024Dec 4, 2024
    • Code for performing RING-MaP and PAIR-MaP analysis
      Python
      MIT License
      4220Updated Nov 23, 2024Nov 23, 2024
    • Small scripts for common tasks.
      HTML
      4000Updated Nov 4, 2024Nov 4, 2024
    • Superfold

      Public
      SuperFold is a pipeline that uses output data from ShapeMapper to model RNA secondary structures, including pseudoknots; identify de novo regions with well-defined and stable structures; and visualize most probable and alternative helices.
      Python
      Other
      6241Updated Oct 7, 2024Oct 7, 2024
    • fpocketR

      Public
      Program to find drug-like RNA-ligand binding pockets.
      Python
      MIT License
      0020Updated Sep 17, 2024Sep 17, 2024
    • Wrapper for running ShapeMapper2 on large numbers of transcript targets.
      Python
      0000Updated Mar 5, 2024Mar 5, 2024
    • Configuration and installation on the Longleaf computing cluster.
      Python
      0200Updated Feb 7, 2024Feb 7, 2024
    • Data and Jupyter notebooks used in the creation of figures for RNAvigate publication.
      HTML
      0000Updated Nov 29, 2023Nov 29, 2023
    • Jupyter Notebook
      0000Updated Oct 26, 2023Oct 26, 2023
    • Figures and analysis of DMS/PAIR-MaP data from "RNA as a proxisome"
      HTML
      0000Updated Oct 10, 2023Oct 10, 2023
    • RNATools

      Public
      Python
      2100Updated Jun 15, 2023Jun 15, 2023
    • SHAPE-MaP both measures RNA flexibility at single-nucleotide resolution and quantifies the uncertainties in these measurements. The deltaSHAPE framework incorporates these uncertainties to allow detection of RNA structural differences between any two states, including the general effect of the cellular environment, protein binding in cells, and …
      Python
      6401Updated Apr 7, 2023Apr 7, 2023
    • arcPlot

      Public
      Code for plotting arcs
      Python
      MIT License
      3100Updated Aug 24, 2022Aug 24, 2022
    • Identifies and processes deletions from illumina sequencing reads
      Python
      0000Updated May 19, 2021May 19, 2021
    • Collection of Scripts to Analyze 2º and 3º RNA Structure
      Python
      1200Updated May 17, 2021May 17, 2021
    • QuShape

      Public
      QuShape enables efficient, reliable, highly automated, and accurate analysis of high-throughput capillary electrophoresis-detected nucleic acid chemical probing experiments.
      Python
      Other
      1120Updated Jun 22, 2020Jun 22, 2020
    • The differential SHAPE experiment uses three reagents, the workhorse 1M7, plus NMIA and 1M6 which together detect higher-order and noncanonical interactions. Among other uses, the resulting three-reagent SHAPE experiment makes possible very accurate modeling of RNA secondary structure.
      Python
      0000Updated Jun 22, 2020Jun 22, 2020
    • This software has been completely rewritten. Please, use shapemapper2, unless you have a good reason to use this instead. ShapeMapper converts raw sequencing files into mutational profiles, creates SHAPE reactivity plots, and provides extensive diagnostic information useful for experiment analysis and troubleshooting.
      Python
      GNU General Public License v3.0
      0000Updated Jun 16, 2020Jun 16, 2020
    • tombo

      Public
      Tombo is a suite of tools primarily for the identification of modified nucleotides from raw nanopore sequencing data.
      Python
      Other
      54000Updated Feb 22, 2019Feb 22, 2019
    • igv

      Public
      Integrative Genomics Viewer. Fast, efficient, scalable visualization tool for genomics data and annotations
      Java
      MIT License
      387000Updated Apr 19, 2018Apr 19, 2018