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Update blog and links
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adelavega committed Jan 4, 2024
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31 changes: 14 additions & 17 deletions blog/2024-1-2-new-year.md
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---
slug: january-2024-updates
title: New Year Updates
authors: alejandro
tags: [neurosynth]
Expand All @@ -8,44 +7,42 @@ Hello Neurosynth Users,

Happy New Year!

2023 was a very exciting year for Neurosynth, having launched our Compose platform to the public and announced it on social media. In the December we’ve saw **over 1,200 new user visits**, with **200 users signing up for an account**! 🚀
2023 was a very exciting year for Neurosynth, having launched our Compose platform to the public and announced it on social media. In the December we’ve saw **over 500 new user visits**, with **200 users signing up for an account**! 🚀

Help us keep this growth going by [sharing our announcement](http://localhost:3000/compose-docs/blog/announcing-ns-compose) with your colleagues. 🧑‍🔬
Help us keep this growth going by [sharing our announcement](./announcing-ns-compose) with your colleagues. 🧑‍🔬

# 🌟 What’s New 🌟

We’ve also continued to introduce new features and improve the user experience. Here’s some highlights:

**Large-scale association tests**
### Large-scale association tests

A key feature that set aside Neurosynth were large-scale association tests” (previously referred to as “reverse inference” tests).
A key feature that set Neurosynth aside were large-scale association maps (previously known as “reverse inference”).

Whereas a typical meta-analysis tells you about the consistency of activation in a set of studies, an association test tells you whether activation in a region occurs *more consistently for studies in your set of studies versus a large reference sample of studies*.
Whereas a typical meta-analysis tells you about if activity is consistently reported in a target set of studies, an association test tells you if **activation occurs more consistently in this set of studies versus a large and diverse reference sample**.

Neurosynth leverages large-scale neuroimaging datasets as a reference to which you can compare the specific studies in given meta-analysis.
That's important, because this allows you to control for base rate differences between regions. Certain regions, such as the insula or lateral PFC for instance, play a very broad role in cognition, and hence are consistently activated for many different tasks and cognitive states. Thus, if you see insula activity in your meta-analysis, you might erroneously conclude that the insula is involved in the cognitive state you're studying. A large-scale association test lets you determine if the activity you observe in a region occurs *more consistently* in your meta-analysis than in other studies, making it possible to make more confident claims that a given region is involved in a particular process, and isn't involved in just about every task.

That's important, because this effectively allows you to control for base rate differences between regions. Certain regions, such as the insula or lateral PFC for instance, play a very broad role in cognition, and hence tend to be consistently activated for many different terms. Thus, if you see insula activity in your meta-analysis, you might erroneously conclude that the insula is involved in the process of your study. A large-scale association test lets you determine if the activity you observe in a region occurs to a greater extent in your meta-analysis than in other studies, making it possible to make more confident claims that a given region is involved in a particular process, and isn't involved in just about every task.

Previously these association tests were available for the automatically generated maps on neurosynth.org. **Now you can perform large-scale association tests for your custom meta-analyses in Neurosynth Compose.**
Previously association tests were available for the automatically generated maps on neurosynth.org. **Now you can perform large-scale association tests for your custom meta-analyses in Neurosynth Compose.**

import Button from '@mui/material/Button';
<Button variant="contained" color="primary" href='tutorial'>

<Button variant="contained" color="primary" href='tutorial/advanced/mkda_association'>
MKDA Chi-Squared Tutorial 🧑‍🎓
</Button>

**User Experience Enhancements**
### UX Enhancements

Based on your valuable feedback, we've made numerous bug fixes and improvements, notably:
Based on your valuable feedback, we've made numerous bug fixes and improvements:

* **Simplified Curation**: The review import page has been removed, and summary information is now added directly to the tag step.

* **Searching UI**: We've replaced the dropdown with a selection gallery, making it easier to choose your preferred search method, and we now pre-populate search names for Neurostore.
* **Searching UI**: We've replaced the dropdown with a selection gallery, making it easier to choose your preferred search method, and we now auto-generate search import names. In addition, resolving duplicates is skipped if none are present.

* **Streamlined Duplicate Resolution**: The 'resolve duplicates' function will only appear if duplicates are present.
* **Improved Editing Workflow**: The editing interface has been improved, streamlining the extraction process.

* **Improved Editing Workflow**: The process of editing studies has been made more straightforward, allowing you to start editing with ease.

We hope you enjoy these changes, and be sure to leave us feedback or ask questions if you have any problems or suggestions.
We hope you enjoy these changes. Be sure to leave us feedback or ask questions if you have any problems or suggestions.


Cheers,
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2 changes: 1 addition & 1 deletion docs/tutorial/advanced/mkda_association.md
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Expand Up @@ -20,7 +20,7 @@ Although this is a useful approach, there is a significant inferential challenge
Thus, perhaps a more useful question is if and where brain activity occurs *more consistently* for studies investigating a task or construct (in our case, nicotine administration) than studies that *do not* elicit that task or construct. The Neurosynth dataset (or any other large-scale neuroimaging datasets) is a useful reference, as it consists of tens of thousands of diverse neuroimaging studies automatically sample from the literature.

## MKDA Chi-Squared

In our example we want to know if and where studies of nicotine administration show more consistent brain activation, than *all other studies* in the Neurosynth database (15,000+ studies).

We can perform this test using the `Multilevel kernel density (MKDA) analysis - Chi-square` analysis, originally introduced in [Wager et al.,](https://doi.org/10.1093/scan/nsm015). For every voxel, we test if a greater proportion of studies in our meta-analysis activate a given voxel than in a large set of studies that *we did not select* for our inclusion criteria.
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4 changes: 2 additions & 2 deletions docusaurus.config.js
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Expand Up @@ -77,8 +77,8 @@ const config = {
},
{to: '/blog', label: 'Blog', position: 'left'},
{
href: 'https://github.com/neurostuff/compose-docs',
label: 'GitHub',
href: 'https://compose.neurosynth.org',
label: 'Compose Home',
position: 'right',
},
],
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