v2.1.2

CHANGELOG

v2.1.1

CHANGELOG

v2.1.0

CHANGELOG

v2.0.3

CHANGELOG

v2.0.1

• patch to fix chrM variants in input VCF

v2.0.0

• New HTML report generation and layout with quarto
• Excel output supported
• Data bundle update
• Singularity/Apptainer support
• CHANGELOG

v1.0.0

• Complete restructure of code and Conda installation routines, contributed largely by the great @pdiakumis
• Updated data bundle
  • ClinVar - Feb 2022
  • CancerMine - Dec 2021
  • UniprotKB - Nov 2021
  • CIViC - Feb 2022
  • GWAS catalog - Dec 2021
• Software upgrade (VEP 105, R/BioConductor)
• New documentation site (https://sigven.github.io/cpsr)

June 2021 release

• VEP 104 , R v4.1
• Multiple database upgrades
• Improved support for interpretation of non-coding variants (VUS)
• No TOML needed
• Larger panel 0

VEP 101 + panel 0 increase

• Increased number of genes in panel 0
• Upgraded VEP
• Multiple data bundle updates

VEP 100 + ACMG update

• Major data updates
• VEP v100
• More panels from Genomics England PanelApp
• Design your own panel from the exploratory panel 0