Release Notes 2025-01-08
Ontology content summary
| Metric | Value |
|---|---|
| Number of subclasses of root | 2851 |
| Number of annotations on CL terms | 13909 |
| Number of synonyms | 6052 |
| Number of unique references | 2137 |
| Number of unique references in definitions | 1604 |
| Number of relationships with CL term as subject | 3972 |
| Number of cellxgene classes | 804 |
| Number of HRA classes | 481 |
Classes added: 53
| Term |
|---|
| melanin-concentrating hormone neuron (CL:4042036) |
| CGRP-expressing neuron (CL:4042034) |
| liver-resident natural killer cell (CL:4047101) |
| caudal ganglionic eminence derived neuron (CL:4042039) |
| myotendinous junction nucleus (CL:4052024) |
| immature neuron (CL:4042028) |
| secretory pericyte (CL:4047032) |
| pituitary gland capillary endothelial cell (CL:4052016) |
| fallopian tube non-ciliated cell (CL:4052019) |
| limbal epithelial stem cell of cornea (CL:4033093) |
| externa theca cell (CL:4052013) |
| immune oligodendroglia (CL:4042031) |
| subpleural fibroblast (CL:4052029) |
| type IIx muscle cell (CL:4052026) |
| intestinal lamina propria fibroblast (CL:4047023) |
| stomach smooth muscle outer longitudinal layer cell (CL:4047035) |
| adventitial fibroblast (CL:4052030) |
| atretic follicular cell of ovary (CL:4033089) |
| respiratory airway secretory cell (CL:4052031) |
| uterine natural killer cell (CL:4052028) |
| granzyme K-associated CD8 T cell (CL:4052021) |
| atretic theca cell (CL:4052027) |
| PAX6 GABAergic cortical interneuron (CL:4042032) |
| endocrine gland capillary endothelial cell (CL:4052015) |
| smooth muscle cell of stomach (CL:4047034) |
| secretory epithelial cell (CL:1100001) |
| transit amplifying cell of gut (CL:4047017) |
| cortical immature neuron (CL:4042029) |
| pro-opiomelanocortin neuron (CL:4042033) |
| sst GABAergic neuron of the striatum (CL:4042037) |
| decidual resident macrophage (CL:4033088) |
| rostral primary motorneuron (CL:4042038) |
| glycinergic-GABAergic amacrine cell (CL:4033091) |
| lipid-associated macrophage (CL:4033086) |
| choroid plexus capillary endothelial cell (CL:4052017) |
| candelabrum cell (CL:4042030) |
| glutamatergic neuron of the basal ganglia (CL:4042040) |
| molecular layer interneuron (CL:4042035) |
| type G cell of stomach (CL:4047025) |
| fallopian tube epithelial cell (CL:4052018) |
| fallopian tube smooth muscle cell (CL:4052022) |
| interna theca cell (CL:4052012) |
| placental resident macrophage (CL:4033087) |
| pre-venule capillary cell (CL:4047030) |
| pancreatic islet capillary endothelial cell (CL:4052014) |
| middle primary motoneuron (CL:4042041) |
| diffuse bipolar 5 cell (CL:4033085) |
| CD57-positive enterocyte (CL:4033092) |
| post-arteriole capillary cell (CL:4047029) |
| lung resident granzyme K-associated CD8 T cell (CL:4052020) |
| luminal endometrial unciliated epithelial cell (CL:4052023) |
| atretic granulosa cell (CL:4033090) |
| neuromuscular junction nucleus (CL:4052025) |
Synonyms added: 116
| Term | New Synonym | Predicate |
|---|---|---|
| limbal epithelial stem cell of cornea (CL:4033093) | LESC | oio:hasRelatedSynonym |
| pro-opiomelanocortin neuron (CL:4042033) | POMC-expressing neuron | oio:hasRelatedSynonym |
| fallopian tube smooth muscle cell (CL:4052022) | oviduct smooth muscle cell | oio:hasBroadSynonym |
| neuromuscular junction nucleus (CL:4052025) | NMJ nuclues | oio:hasRelatedSynonym |
| CGRP-expressing neuron (CL:4042034) | CGRP-expressing interneuron | oio:hasRelatedSynonym |
| decidual cell (CL:2000002) | decidualized endometrial stromal cell | oio:hasExactSynonym |
| oviduct secretory cell (CL:1001591) | oviduct glandular cell | oio:hasRelatedSynonym |
| respiratory tract multiciliated cell (CL:4030034) | respiratory ciliated cell | oio:hasExactSynonym |
| type IIx muscle cell (CL:4052026) | type 2x muscle fiber | oio:hasExactSynonym |
| decidual resident macrophage (CL:4033088) | maternal decidual macrophage | oio:hasBroadSynonym |
| duodenum secretory cell (CL:1001589) | duodenum glandular cells | oio:hasNarrowSynonym |
| transit amplifying cell of gut (CL:4047017) | transit-amplifying cell | oio:hasBroadSynonym |
| diffuse bipolar 5 cell (CL:4033085) | DB5 cell | oio:hasRelatedSynonym |
| respiratory tract hillock cell (CL:4030023) | hillock cell of respiratory tract | oio:hasExactSynonym |
| granzyme K-associated CD8 T cell (CL:4052021) | granzyme K+ CD8 T cell | oio:hasExactSynonym |
| cortical immature neuron (CL:4042029) | cIN | oio:hasRelatedSynonym |
| luminal endometrial unciliated epithelial cell (CL:4052023) | luminal cell of endometrium | oio:hasBroadSynonym |
| pulmonary neuroendocrine cell (CL:1000223) | lung neuroendocrine cell | oio:hasExactSynonym |
| polymodal neuron (CL:0000102) | polymodal sensory neuron | oio:hasRelatedSynonym |
| liver-resident natural killer cell (CL:4047101) | liver NK cell | oio:hasExactSynonym |
| respiratory tract suprabasal cell (CL:4033048) | respiratory suprabasal cell | oio:hasExactSynonym |
| liver-resident natural killer cell (CL:4047101) | he-NK | oio:hasExactSynonym |
| fallopian tube multiciliated cell (CL:4030007) | fallopian tube ciliated cell | oio:hasExactSynonym |
| molecular layer interneuron (CL:4042035) | MLI | oio:hasRelatedSynonym |
| CAP motoneuron (CL:0000532) | caudal primary motor neuron | oio:hasRelatedSynonym |
| immature neuron (CL:4042028) | IN | oio:hasRelatedSynonym |
| fallopian tube smooth muscle cell (CL:4052022) | uterine tube smooth muscle cell | oio:hasExactSynonym |
| skin sebocyte (CL:0002140) | acinar cell of sebaceous gland | oio:hasBroadSynonym |
| interna theca cell (CL:4052012) | interna TC | oio:hasRelatedSynonym |
| lipid-associated macrophage (CL:4033086) | LAM | oio:hasRelatedSynonym |
| myotendinous junction nucleus (CL:4052024) | myotendinous junction myonuclei | oio:hasExactSynonym |
| liver-resident natural killer cell (CL:4047101) | intrahepatic NK | oio:hasExactSynonym |
| respiratory airway secretory cell (CL:4052031) | terminal and respiratory bronchioles secretory cell | oio:hasRelatedSynonym |
| myotendinous junction nucleus (CL:4052024) | MTJ nucleus | oio:hasRelatedSynonym |
| multiciliated epithelial cell (CL:0005012) | multi-ciliated epithelial cell | oio:hasExactSynonym |
| fallopian tube epithelial cell (CL:4052018) | oviduct epithelial cell | oio:hasBroadSynonym |
| uterine natural killer cell (CL:4052028) | endometrial natural killer cell | oio:hasNarrowSynonym |
| lung resident granzyme K-associated CD8 T cell (CL:4052020) | lung resident CD8-GZMK | oio:hasRelatedSynonym |
| pre-venule capillary cell (CL:4047030) | Cap-Venous endothelial cell | oio:hasExactSynonym |
| stomach neuroendocrine cell (CL:1000222) | diffuse endocrine system cell | oio:hasBroadSynonym |
| candelabrum cell (CL:4042030) | candelabrum interneuron | oio:hasExactSynonym |
| respiratory tract hillock cell (CL:4030023) | respiratory hillock cell | oio:hasExactSynonym |
| granzyme K-associated CD8 T cell (CL:4052021) | CD8-GZMK cell | oio:hasRelatedSynonym |
| melanin-concentrating hormone neuron (CL:4042036) | MCH neuron | oio:hasRelatedSynonym |
| Lugaro cell (CL:0011006) | globular cell | oio:hasRelatedSynonym |
| fallopian tube epithelial cell (CL:4052018) | uterine tube epithelial cell | oio:hasExactSynonym |
| stomach neuroendocrine cell (CL:1000222) | DES cell | oio:hasBroadSynonym |
| pancreatic islet capillary endothelial cell (CL:4052014) | islet endothelial cell | oio:hasBroadSynonym |
| liver-resident natural killer cell (CL:4047101) | hepatic NK | oio:hasExactSynonym |
| CGRP-expressing neuron (CL:4042034) | CGRP-positive neuron | oio:hasRelatedSynonym |
| sst GABAergic neuron of the striatum (CL:4042037) | striatal SST+ IN | oio:hasRelatedSynonym |
| respiratory tract epithelial cell (CL:0002368) | respiratory epithelial cell | oio:hasExactSynonym |
| middle primary motoneuron (CL:4042041) | MiP | oio:hasRelatedSynonym |
| interna theca cell (CL:4052012) | inTC | oio:hasRelatedSynonym |
| neuromuscular junction nucleus (CL:4052025) | neuromuscular junction nuclei | oio:hasExactSynonym |
| skin sebocyte (CL:0002140) | acinar cell of skin sebaceous gland | oio:hasExactSynonym |
| candelabrum cell (CL:4042030) | CC | oio:hasRelatedSynonym |
| epididymis secretory cell (CL:1001590) | epididymis glandular cell | oio:hasRelatedSynonym |
| respiratory airway secretory cell (CL:4052031) | RAS cell | oio:hasRelatedSynonym |
| externa theca cell (CL:4052013) | externa TC | oio:hasRelatedSynonym |
| liver-resident natural killer cell (CL:4047101) | lr-NK | oio:hasExactSynonym |
| externa theca cell (CL:4052013) | exTC | oio:hasRelatedSynonym |
| luminal endometrial unciliated epithelial cell (CL:4052023) | endometrial luminal epithelial cell | oio:hasBroadSynonym |
| lung multiciliated epithelial cell (CL:1000271) | lung ciliated cell | oio:hasExactSynonym |
| intestinal lamina propria fibroblast (CL:4047023) | S1 fibroblast | oio:hasRelatedSynonym |
| CD57-positive enterocyte (CL:4033092) | CD57+ enterocyte | oio:hasExactSynonym |
| glandular endometrial multiciliated epithelial cell (CL:4030042) | glandular endometrial ciliated epithelial cell | oio:hasExactSynonym |
| glycinergic-GABAergic amacrine cell (CL:4033091) | glycinergic/GABAergic amacrine neuron | oio:hasExactSynonym |
| immune oligodendroglia (CL:4042031) | immune oligodendrocyte | oio:hasExactSynonym |
| pancreatic islet capillary endothelial cell (CL:4052014) | pancreatic islet endothelial cell | oio:hasBroadSynonym |
| immune oligodendroglia (CL:4042031) | ImOLG | oio:hasRelatedSynonym |
| atretic granulosa cell (CL:4033090) | apoptotic granulosa cell | oio:hasRelatedSynonym |
| immune oligodendroglia (CL:4042031) | ImOL | oio:hasRelatedSynonym |
| granzyme K-associated CD8 T cell (CL:4052021) | TteK CD8 cell | oio:hasRelatedSynonym |
| foveolar cell of stomach (CL:0002179) | surface mucosal cell of stomach | oio:hasExactSynonym |
| airway submucosal gland duct multiciliated cell (CL:4033055) | airway submucosal gland duct ciliated cell | oio:hasExactSynonym |
| limbal epithelial stem cell of cornea (CL:4033093) | LSC | oio:hasRelatedSynonym |
| glandular endometrial unciliated epithelial cell (CL:0002656) | glandular cell of endometrium | oio:hasBroadSynonym |
| liver-resident natural killer cell (CL:4047101) | liver-specific natural killer cell | oio:hasExactSynonym |
| rostral primary motorneuron (CL:4042038) | RoP | oio:hasRelatedSynonym |
| multiciliated epithelial cell of the bronchus (CL:0002332) | ciliated epithelial cell of the bronchus | oio:hasExactSynonym |
| CGRP-expressing neuron (CL:4042034) | Calcitonin gene-related peptide neuron | oio:hasExactSynonym |
| type IIx muscle cell (CL:4052026) | type IIx muscle fiber | oio:hasExactSynonym |
| granzyme K-associated CD8 T cell (CL:4052021) | tissue-enriched expressing GzmK CD8 cell | oio:hasExactSynonym |
| type IIx muscle cell (CL:4052026) | type 2x fiber | oio:hasExactSynonym |
| parietal cell (CL:0000162) | gastric parietal cell | oio:hasExactSynonym |
| transit amplifying cell of gut (CL:4047017) | TA cell | oio:hasRelatedSynonym |
| placental resident macrophage (CL:4033087) | placental macrophage | oio:hasBroadSynonym |
| limbal epithelial stem cell of cornea (CL:4033093) | limbal stem cell | oio:hasExactSynonym |
| stromal cell of endometrium (CL:0002255) | stromal cell of uterus | oio:hasBroadSynonym |
| pro-opiomelanocortin neuron (CL:4042033) | POMC neuron | oio:hasRelatedSynonym |
| CAP motoneuron (CL:0000532) | cap cell | oio:hasRelatedSynonym |
| liver-resident natural killer cell (CL:4047101) | hepatic natural killer cells | oio:hasExactSynonym |
| immune oligodendroglia (CL:4042031) | Im-OL | oio:hasRelatedSynonym |
| Hofbauer cell (CL:3000001) | fetal Hofbauer cell | oio:hasExactSynonym |
| myotendinous junction nucleus (CL:4052024) | myotendinous junction nuclei | oio:hasExactSynonym |
| glandular secretory epithelial cell (CL:0000150) | glandular epithelial cell | oio:hasExactSynonym |
| small intestine secretory cell (CL:1001598) | small intestinal glandular cell | oio:hasNarrowSynonym |
| granzyme K-associated CD8 T cell (CL:4052021) | GZMK high CD8+ T effector memory cell | oio:hasNarrowSynonym |
| uterine cervix secretory cell (CL:1001587) | uterine cervix glandular cell | oio:hasRelatedSynonym |
| interneuron (CL:0000099) | CNS interneuron | oio:hasRelatedSynonym |
| uterine natural killer cell (CL:4052028) | uNK cell | oio:hasRelatedSynonym |
| CAP motoneuron (CL:0000532) | CaP motorneuron | oio:hasExactSynonym |
| respiratory tract multiciliated cell (CL:4030034) | respiratory multiciliated cell | oio:hasExactSynonym |
| type IIx muscle cell (CL:4052026) | type 2x muscle cell | oio:hasExactSynonym |
| sst GABAergic neuron of the striatum (CL:4042037) | SOM cell | oio:hasBroadSynonym |
| decidual resident macrophage (CL:4033088) | decidual macrophage | oio:hasBroadSynonym |
| limbal epithelial stem cell of cornea (CL:4033093) | limbal epithelial stem cell | oio:hasExactSynonym |
| neuromuscular junction nucleus (CL:4052025) | neuromuscular junction myonuclei | oio:hasExactSynonym |
| liver-resident natural killer cell (CL:4047101) | liver resident natural killer cell | oio:hasExactSynonym |
| sebocyte (CL:0000317) | sebum secreting cell | oio:hasExactSynonym |
| endometrial multiciliated epithelial cell (CL:4030040) | endometrial ciliated epithelial cell | oio:hasExactSynonym |
| immune oligodendroglia (CL:4042031) | imOLG | oio:hasRelatedSynonym |
| multiciliated columnar cell of tracheobronchial tree (CL:0002145) | ciliated columnar cell of tracheobronchial tree | oio:hasExactSynonym |
| luminal endometrial multiciliated epithelial cell (CL:4030041) | luminal endometrial ciliated epithelial cell | oio:hasExactSynonym |
| respiratory tract goblet cell (CL:0002370) | respiratory goblet cell | oio:hasExactSynonym |
Text definitions changed: 64
| Term | Old Text Definition | New Text Definition |
|---|---|---|
| stromal cell (CL:0000499) | A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere. | A connective tissue cell of an organ found in the loose connective tissue. |
| CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell (CL:0002454) | Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-negative, CD8_alpha-negative and is CD205-positive. | CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-negative, CD8-alpha-negative and is CD205-positive. |
| intestinal tuft cell (CL:0019032) | Any brush cell that is part of the intestinal epithelium. | Any brush cell that is part of the intestinal epithelium. |
| CD8-alpha-low Langerhans cell (CL:0001015) | CD8_alpha-low Langerhans cell is a Langerhans cell that is CD205-high and is CD8_alpha-low. | CD8-alpha-low Langerhans cell is a Langerhans cell that is CD205-high and is CD8-alpha-low. |
| CD8-alpha-positive plasmacytoid dendritic cell (CL:0002456) | A CD11c-low plasmacytoid dendritic cell that is CD8alpha-positive and CD4-positive. | A CD11c-low plasmacytoid dendritic cell that is CD8-alpha-positive and CD4-positive. |
| immature CD8-alpha-negative CD11b-positive dendritic cell (CL:0000997) | Immature CD8_alpha-negative CD11b-positive dendritic cell is a CD8_alpha-negative CD11b-positive dendritic cell that is CD80-low, CD86-low, and MHCII-low. | Immature CD8-alpha-negative CD11b-positive dendritic cell is a CD8-alpha-negative CD11b-positive dendritic cell that is CD80-low, CD86-low, and MHCII-low. |
| CD4-positive CD11b-positive dendritic cell (CL:0000999) | CD8_alpha-negative CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-positive and is CD205-negative and CD8_alpha-negative. | CD8-alpha-negative CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-positive and is CD205-negative and CD8-alpha-negative. |
| type G enteroendocrine cell (CL:0000508) | An endocrine cell found in the pyloric gland mucosa (antral mucosa) of the stomach of mammals and responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli. | An endocrine cell found in the stomach and duodenum and is responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli. |
| sebocyte (CL:0000317) | A cell secreting sebun, an oily substance secreted by sebaceous glands, composed of keratin, fat, and cellular debris. | An epithelial cell that is part of a sebaceous gland. This cell produces and secretes sebum, an oily, lipid-rich substance, through holocrine secretion where the entire cell ruptures to release its contents. |
| CD8-alpha-negative thymic conventional dendritic cell (CL:0002460) | A conventional thymic dendritic cell that is CD8alpha-negative. | A conventional thymic dendritic cell that is CD8-alpha-negative. |
| epithelial cell of large intestine (CL:0002253) | An epithelial cell of the large intestine. | An epithelial cell of the lining of the large intestine. |
| colonocyte (CL:1000347) | A columnar cell of the colon that is part of the colonic epithelium. | An enterocyte (absorptive epithelial cell) of the colonic epithelium, characterized by a columnar shape. This cell is responsible for the absorption, transport, and metabolization of short-chain fatty acids (SCFAs) produced by gut bacteria, as well as the transport and absorption of water and electrolytes. |
| CD8-alpha-positive thymic conventional dendritic cell (CL:0002059) | A conventional thymic dendritic cell that is CD8alpha-positive. | A conventional thymic dendritic cell that is CD8-alpha-positive. |
| mature CD8-alpha-low Langerhans cell (CL:0001020) | Mature CD8_alpha-low Langerhans cell is a CD8_alpha-low Langerhans cell that that is CD80-high, CD86-high, MHCII-high and is CD83-positive. | Mature CD8-alpha-low Langerhans cell is a CD8-alpha-low Langerhans cell that that is CD80-high, CD86-high, MHCII-high and is CD83-positive. |
| obsolete CNS interneuron (CL:0000402) | An interneuron that has its cell body in a central nervous system. | OBSOLETE. An interneuron that has its cell body in a central nervous system. |
| stromal cell of endometrium (CL:0002255) | A stromal cell of the endometrium that is fibroblastic in appearance. During decidualization this cell may differentiate into a decidual stromal cell. | A stromal cell of the endometrium, characterized by its fibroblast-like morphology, regenerative capacity, and ability to undergo decidualization. It differentiates into a decidual stromal cell during pregnancy, essential for embryo implantation and maintenance. This cell is involved in tissue proliferation, remodeling, and breakdown, responding to hormonal changes, particularly estrogen and progesterone. |
| skin sebocyte (CL:0002140) | A sebum secreting cell of the skin that secretes sebum into the hair follicles. | An acinar cell that is part of a skin sebaceous gland. This cell produces and secretes sebum into hair follicles. |
| fallopian tube secretory epithelial cell (CL:4030006) | An epithelial cell that is part of the fallopian tube epithelium that secretes mucous fluid and oviduct-specific products through the stimulation of estrogen and luteinizing hormone. The fallopian tube secretory cell has approximately the same height as the ciliated cell and is usually a more narrow columnar cell. The nucleus is ovoid and perpendicular to the long axis of the cell. The chromatin is more dense and the nucleolus smaller than that seen in the ciliated cell. | An epithelial cell that is part of the fallopian tube that secretes mucus and oviduct-specific products in response to hormonal stimulation from estrogen and luteinizing hormone. This fallopian tube secretory cell is similar in height to the ciliated cell, but typically exhibits a more narrow, columnar shape. Its nucleus is ovoid and oriented perpendicular to the cell's long axis, with denser chromatin and a smaller nucleolus compared to the ciliated cell. |
| Vgamma5-negative CD8-alpha alpha positive gamma-delta intraepithelial T cell (CL:0002514) | A CD8alpha alpha positive gamma-delta intraepithelial T cell that does not express a TCR partially encoded by the Vgamma5 gene segment. | A CD8-alpha alpha positive gamma-delta intraepithelial T cell that does not express a TCR partially encoded by the Vgamma5 gene segment. |
| fallopian tube multiciliated cell (CL:4030007) | An epithelial ciliated cell that is part of the fallopian tube. This cell type is found mainly on the apex of the mucosal folds and contributes, together with peristaltic contractions, to the self-propulsion of spermatozoa, the transport of ovum during ovulation and the transport of the fertilized ovum to the intramural fallopian tube. A fallopian tube ciliated cell has a columnar shape and contains an oval or round nucleus, often located perpendicular or parallel to the long axis of the cell. | A multi-ciliated epithelial cell that is part of the fallopian tube, mainly found on the apex of the mucosal folds. This cell exhibits a columnar shape with an oval nucleus and is characterized by the presence of cilia on its surface. The coordinated beating of these cilia, together with peristaltic contractions, contributes to the self-propulsion of spermatozoa, the transport of ovum during ovulation and the transport of the fertilized ovum to the intramural fallopian tube. |
| peptic cell (CL:0000155) | A cell that is usually basal in position, cuboidal with round nucleus, short microvilli, secretes pepsinogen. | An epithelial cell of the stomach that is part of the fundic gastric gland. This cell is characterized by a basally located nucleus, abundant rough endoplasmic reticulum, and large apical secretory granules. It produces and secretes pepsinogen, the inactive precursor of the digestive enzyme pepsin. |
| airway submucosal gland duct multiciliated cell (CL:4033055) | A ciliated cell that is part of a ciliated duct of an airway submucosal gland. | A multi-ciliated epithelial cell located in ciliated duct of an airway submucosal gland, characterized by a columnar shape and motile cilia on its apical surface. |
| foveolar cell of stomach (CL:0002179) | An epithelial cell within one of the pits in the embryonic gastric mucosa from which the gastric glands develop . | A simple columnar cell that populates the entire luminal surface including the gastric pits. This cell types secrete mucus to form a thick protective, lubricant layer over the gastric wall. |
| epithelial cell of small intestine (CL:0002254) | An epithelial cell of the small intestine. | An epithelial cell of the lining of the small intestine. |
| respiratory tract multiciliated cell (CL:4030034) | A ciliated cell of the respiratory system. Ciliated cells are present in airway epithelium. | A multiciliated epithelial cell located in the respiratory tract epithelium, characterized by a columnar shape and motile cilia on its apical surface. This cell develops through a highly orchestrated process, transitioning from a basal progenitor via an intermediate deuterosomal cell stage that generates centrioles essential for ciliogenesis. |
| brush cell of tracheobronchial tree (CL:0002075) | Infrequent type of columnar epithelial cell. This cell is characterized by the presence of a tuft of blunt, squat microvilli (approximately 120-140/cell) on the cell surface. The microvilli contain filaments that stretch into the underlying cytoplasm. They have a distinctive pear shape with a wide base and a narrow microvillous apex. Function not known. | A rare type of columnar epithelial cell that is part of the tracheobronchial epithelium. This cell is characterized by a distinctive tuft of apical microvilli, which extends into the cytoplasm, and a pear-shaped morphology, broad at the base and tapering to a narrow apex. It plays vital roles in chemosensation, producing cytokines like IL-25, and enhancing mucociliary clearance through acetylcholine release to support mucus movement and airway defense. |
| glandular secretory epithelial cell (CL:0000150) | A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules. | An epithelial cell, located in a gland, that is specialised for the synthesis and secretion of specific biomolecules, such as hormones, or mucous. |
| intestinal epithelial cell (CL:0002563) | An epithelial cell of the intestine. | An epithelial cell of the lining of the intestine. |
| paneth cell (CL:0000510) | An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix. | An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix. |
| inner medulla vasa recta descending limb cell (CL:1001286) | Any vasa recta descending limb cell that is part of some inner medulla vasa recta descending limb. | Any vasa recta descending limb cell that is part of some inner medulla descending vasa recta. |
| intestine goblet cell (CL:0019031) | Goblet cells reside throughout the length of the small and large intestine and are responsible for the production and maintenance of the protective mucus blanket by synthesizing and secreting high-molecular-weight glycoproteins known as mucins. Human intestinal goblet cells secrete the MUC2 mucin, as well as a number of typical mucus components: CLCA1, FCGBP, AGR2, ZG16, and TFF3. | Goblet cells reside throughout the length of the small and large intestine and are responsible for the production and maintenance of the protective mucus blanket by synthesizing and secreting high-molecular-weight glycoproteins known as mucins. Human intestinal goblet cells secrete the MUC2 mucin, as well as a number of typical mucus components: CLCA1, FCGBP, AGR2, ZG16, and TFF3. |
| respiratory tract epithelial cell (CL:0002368) | An endo-epithelial cell of the respiratory tract. | An epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin. |
| multiciliated epithelial cell of the bronchus (CL:0002332) | A ciliated cell of the bronchus. | A multi-ciliated epithelial cell located in the bronchus epithelium, characterized by a columnar shape and motile cilia on its apical surface. |
| pulmonary neuroendocrine cell (CL:1000223) | A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Lung neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Lung neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury. | A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Pulmonary neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Pulmonary neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury. |
| parietal cell (CL:0000162) | A large, oval stomach epithelial cell with a central nucleus; source of gastric acid. Secretes HCl. | An epithelial cell of the stomach that is part of the fundic gastric gland. This cell is characterized by its pyramidal shape, abundant mitochondria, and a complex network of secretory canaliculi lined with microvilli. It secretes hydrochloric acid into the stomach lumen and produces intrinsic factor, essential for vitamin B12 absorption. |
| outer medulla vasa recta ascending limb cell (CL:1001210) | Any vasa recta ascending limb cell that is part of some outer medulla vasa recta ascending limb. | Any vasa recta ascending limb cell that is part of some outer medulla ascending vasa recta. |
| parathyroid glandular cell (CL:1001593) | Glandular cell of parathyroid epithelium. Example: Parathyroid chief cell and parathyroid oxyphil cells. | Glandular (secretory) cell of parathyroid epithelium. |
| peripheral sensory neuron (CL:3000004) | Peripheral sensory neuron. | A neuron type that is located in a peripheral nervous system and it transmits sensory information from the peripheral (PNS) to the central nervous system (CNS). A sensory neuron converts physical (light, sound, touch) or chemical (such as taste and smell) stimuli into an electrical signal through a process known as sensory transduction. The function of a sensory neuron is to carry informations from the external environment and internal body conditions to the central nervous system for further processing. |
| immature CD8-alpha-low Langerhans cell (CL:0001018) | Immature CD8_alpha-low Langerhans cell is a CD8_alpha-low Langerhans cell that is CD80-low, CD86-low, and MHCII-low. | Immature CD8-alpha-low Langerhans cell is a CD8-alpha-low Langerhans cell that is CD80-low, CD86-low, and MHCII-low. |
| obsolete surface mucosal cell of stomach (CL:0002182) | A simple columnar cell that populates the entire luminal surface including the gastric pits. This cell types secrete mucus to form a thick protective, lubricant layer over the gastric wall. | OBSOLETE. A simple columnar cell that populates the entire luminal surface including the gastric pits. This cell types secrete mucus to form a thick protective, lubricant layer over the gastric wall. |
| inner medulla vasa recta ascending limb cell (CL:1001209) | Any vasa recta ascending limb cell that is part of some inner medulla vasa recta ascending limb. | Any vasa recta ascending limb cell that is part of some inner medulla ascending vasa recta. |
| anterior lateral line ganglion neuron (CL:0008021) | Any neuron that has its soma located in some anterior lateral line ganglion. | Any peripheral nervous system neuron that has its soma located in some anterior lateral line ganglion. |
| posterior lateral line ganglion neuron (CL:1000245) | Any neuron that has its soma located in some posterior lateral line ganglion. | Any peripheral nervous system neuron that has its soma located in some posterior lateral line ganglion. |
| immature CD8-alpha-positive CD11b-negative dendritic cell (CL:0001004) | Immature CD8_alpha-positive CD11b-negative dendritic cell is a CD8_alpha-positive CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low. | Immature CD8-alpha-positive CD11b-negative dendritic cell is a CD8-alpha-positive CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low. |
| intestinal crypt stem cell of colon (CL:0009043) | An intestinal crypt stem cell that is located in the colon. | An intestinal crypt stem cell that is located in the crypt of Lieberkuhn of colon. |
| immature CD8-alpha-negative CD11b-negative dendritic cell (CL:0001001) | Immature CD8_alpha-negative CD11b-negative dendritic cell is a CD8_alpha-negative CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low. | Immature CD8-alpha-negative CD11b-negative dendritic cell is a CD8-alpha-negative CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low. |
| CD8-alpha-positive CD11b-negative dendritic cell (CL:0001000) | CD8_alpha-positive CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative and is CD205-positive and CD8_alpha-positive. | CD8-alpha-positive CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative and is CD205-positive and CD8-alpha-positive. |
| mucus secreting cell (CL:0000319) | Any secretory cell that is capable of some mucus secretion. | Any cell that is capable of some mucus secretion. |
| urethra urothelial cell (CL:1001430) | Any urothelial cell that is part of some urethra urothelium. | A urothelial cell that is part of the urethra urothelium. This cell plays a crucial role in maintaining the urethral barrier function, protecting against toxic substances in urine, sensing environmental changes, and defending against pathogen entry. |
| theca cell (CL:0000503) | A flattened stroma cell forming a sheath or theca outside the basal lamina lining the mature ovarian follicle. Thecal interstitial or stromal cells are steroidogenic, and produce primarily androgens which serve as precusors of estrogens in the granulosa cells. | A specialized stromal cell that forms the theca layer outside the basal lamina lining the ovarian follicle, appearing during the secondary follicle stage. |
| outer medulla vasa recta descending limb cell (CL:1001287) | Any vasa recta descending limb cell that is part of some outer medulla vasa recta descending limb. | Any vasa recta descending limb cell that is part of some outer medulla descending vasa recta. |
| CD8-alpha-negative plasmacytoid dendritic cell (CL:0002455) | A CD11c-low plasmacytoid dendritic cell that is CD8alpha-negative and CD4-positive. | A CD11c-low plasmacytoid dendritic cell that is CD8-alpha-negative and CD4-positive. |
| mature CD8-alpha-negative CD11b-positive dendritic cell (CL:0001003) | Mature CD8_alpha-negative CD11b-positive dendritic cell is a CD8_alpha-negative CD11b-positive dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. | Mature CD8-alpha-negative CD11b-positive dendritic cell is a CD8-alpha-negative CD11b-positive dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. |
| stomach neuroendocrine cell (CL:1000222) | Any neuroendocrine cell that is part of some stomach. | A specialised neuroendocrine cell located in the gastric mucosa that regulates digestive processes including acid secretion and gut motility. This cell stores hormones in large dense core vesicles and synaptic-like microvesicles. |
| mature CD8-alpha-negative CD11b-negative dendritic cell (CL:0001002) | Mature CD8_alpha-negative CD11b-negative dendritic cell is a CD8_alpha-negative CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. | Mature CD8-alpha-negative CD11b-negative dendritic cell is a CD8-alpha-negative CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. |
| thalamic excitatory neuron (CL:4023068) | An excitatory neuron that has its soma located in the thalamic complex. | An excitatory neuron that has its soma located in the thalamic complex. This neuron type can be involved in a series of circuits related to sensory integration, motor integration, pain processing, social behaviour and reward response. |
| ureter urothelial cell (CL:1000706) | Any urothelial cell that is part of some urothelium of ureter. | A urothelial cell that is part of the urothelium of ureter. |
| Vgamma5-positive CD8-alpha alpha positive gamma-delta intraepithelial T cell (CL:0002513) | A CD8alpha alpha positive gamma-delta intraepithelial T cell that expresses a TCR encoded in part by the Vgamma5 gene segment. | A CD8-alpha alpha positive gamma-delta intraepithelial T cell that expresses a TCR encoded in part by the Vgamma5 gene segment. |
| CD8-alpha-negative CD11b-negative dendritic cell (CL:0000998) | CD8_alpha-negative CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative CD8_alpha-negative and is CD205-positive. This cell is able to cross- present antigen to CD8-alpha-positive T cells. | CD8-alpha-negative CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative CD8-alpha-negative and is CD205-positive. This cell is able to cross- present antigen to CD8-alpha-positive T cells. |
| glandular endometrial unciliated epithelial cell (CL:0002656) | A glandular epithelial cell of the endometrium. | A glandular epithelial cell of the endometrium. Following ovulation, these cells secrete a glycogen-rich substance known as histotroph or uterine milk, which nourishes the embryo if implantation occurs. |
| epithelial cell of esophagus (CL:0002252) | An epithelial cell of the esophagus. | An epithelial cell of the lining of the esophagus. |
| respiratory tract suprabasal cell (CL:4033048) | A respiratory epithelial cell with topographic nuclear position in between the basal and luminal cell of the airway epithelium. This non-basal, intermediate cell has limited proliferative capacity, ultrastructural features of basal cells and no defined features of the typically differentiated cellular phenotypes. | A respiratory epithelial cell derived from a basal cell, with a topographic nuclear position between the basal and luminal cells of the airway epithelium. This non-basal, intermediate progenitor cell has limited proliferative capacity and can differentiate into multiciliated, secretory, or rare airway cells (ionocytes, tuft cells, neuroendocrine cells). It shares some ultrastructural features with basal cells but lacks the defined characteristics of fully differentiated cellular phenotypes. |
| mature CD8-alpha-positive CD11b-negative dendritic cell (CL:0001005) | Mature CD8_alpha-positive CD11b-negative dendritic cell is a CD8_alpha-positive CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. | Mature CD8-alpha-positive CD11b-negative dendritic cell is a CD8-alpha-positive CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. |
| Hofbauer cell (CL:3000001) | A tissue-resident macrophage that is part of the placenta. A Hofbauer cell expresses high levels of growth factors and metalloproteinases that support vasculogenesis, angiogenesis, branching morphogenesis and tissue remodeling. A Hofbauer cell has a fetal origin and is present throughout pregnancy. | A tissue-resident macrophage that is part of the placenta. A Hofbauer cell expresses high levels of growth factors and metalloproteinases that support vasculogenesis, angiogenesis, branching morphogenesis and tissue remodeling. A Hofbauer cell has a fetal origin, is found in the villous stroma, chorion, and amnion, and is present throughout pregnancy. |
Mappings added: 101
| Subject | Predicate | Object |
|---|---|---|
| paneth cell of colon (CL:0009009) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0009009 |
| cardiac muscle cell (CL:0000746) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000746 |
| foveolar cell of stomach (CL:0002179) | oio:hasDbXref | FMA:62949 |
| endosteal cell (CL:0002157) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002157 |
| ileal goblet cell (CL:1000326) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000326 |
| smooth muscle cell of small intestine (CL:1000275) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000275 |
| regular atrial cardiac myocyte (CL:0002129) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002129 |
| medullary thymic epithelial cell (CL:0002365) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002365 |
| bronchial goblet cell (CL:1000312) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000312 |
| smooth muscle fiber of ileum (CL:1000278) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000278 |
| endothelial cell of uterus (CL:0009095) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0009095 |
| smooth muscle cell of sphincter of pupil (CL:0002243) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002243 |
| sphincter associated smooth muscle cell (CL:0000358) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000358 |
| granulocyte monocyte progenitor cell (CL:0000557) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000557 |
| cerebral cortex endothelial cell (CL:1001602) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1001602 |
| decidual cell (CL:2000002) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_2000002 |
| extravillous trophoblast (CL:0008036) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0008036 |
| intestinal enteroendocrine cell (CL:1001516) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1001516 |
| enteroendocrine cell of small intestine (CL:0009006) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0009006 |
| kidney resident macrophage (CL:1000698) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000698 |
| paneth cell of epithelium of small intestine (CL:1000343) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000343 |
| colon macrophage (CL:0009038) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0009038 |
| ventricular cardiac muscle cell (CL:2000046) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_2000046 |
| mature microglial cell (CL:0002629) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002629 |
| mesodermal cell (CL:0000222) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000222 |
| central nervous system macrophage (CL:0000878) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000878 |
| smooth muscle cell of trachea (CL:0002600) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002600 |
| kidney connecting tubule epithelial cell (CL:1000768) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000768 |
| epithelial cell of urethra (CL:1000296) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000296 |
| endothelial cell of sinusoid (CL:0002262) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002262 |
| tracheal goblet cell (CL:1000329) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000329 |
| fast muscle cell (CL:0000190) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000190 |
| melanocyte of skin (CL:1000458) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000458 |
| kidney efferent arteriole cell (CL:1001009) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1001009 |
| slow muscle cell (CL:0000189) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000189 |
| kidney proximal straight tubule epithelial cell (CL:1000839) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000839 |
| kidney proximal convoluted tubule epithelial cell (CL:1000838) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000838 |
| colon goblet cell (CL:0009039) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0009039 |
| tongue muscle cell (CL:0002673) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002673 |
| regular cardiac myocyte (CL:0002098) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002098 |
| aortic smooth muscle cell (CL:0002539) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002539 |
| surface ectodermal cell (CL:0000114) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000114 |
| trophoblast cell (CL:0000351) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000351 |
| male germ cell (CL:0000015) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000015 |
| gamete (CL:0000300) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000300 |
| myometrial cell (CL:0002366) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002366 |
| bronchial smooth muscle cell (CL:0002598) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002598 |
| gut endothelial cell (CL:0000131) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000131 |
| vascular associated smooth muscle cell (CL:0000359) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000359 |
| transit amplifying cell of small intestine (CL:0009012) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0009012 |
| skeletal muscle satellite cell (CL:0000594) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000594 |
| serous cell of epithelium of bronchus (CL:1000331) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000331 |
| sperm (CL:0000019) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000019 |
| placental villous trophoblast (CL:2000060) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_2000060 |
| enteric smooth muscle cell (CL:0002504) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002504 |
| skeletal muscle fibroblast (CL:0011027) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0011027 |
| lens fiber cell (CL:0011004) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0011004 |
| kidney loop of Henle descending limb epithelial cell (CL:1001021) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1001021 |
| endothelial cell of hepatic sinusoid (CL:1000398) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000398 |
| bladder urothelial cell (CL:1001428) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1001428 |
| smooth muscle cell of the pulmonary artery (CL:0002591) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002591 |
| macula densa epithelial cell (CL:1000850) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000850 |
| smooth muscle myoblast (CL:0000514) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000514 |
| basal cell of epithelium of bronchus (CL:1000349) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000349 |
| male gamete (CL:0000408) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000408 |
| anterior lens cell (CL:0002223) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002223 |
| microglial cell (CL:0000129) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000129 |
| dermis lymphatic vessel endothelial cell (CL:2000011) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_2000011 |
| tracheobronchial smooth muscle cell (CL:0019019) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0019019 |
| ciliary muscle cell (CL:1000443) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000443 |
| preosteoblast (CL:0007010) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0007010 |
| osteoclast (CL:0000092) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000092 |
| basal cell of epithelium of trachea (CL:1000348) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000348 |
| lung macrophage (CL:1001603) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1001603 |
| sebaceous gland cell (CL:2000021) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_2000021 |
| kidney collecting duct intercalated cell (CL:1001432) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1001432 |
| smooth muscle cell of prostate (CL:1000487) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000487 |
| tuft cell of colon (CL:0009041) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0009041 |
| microfold cell of epithelium of small intestine (CL:1000353) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000353 |
| transit amplifying cell of colon (CL:0009011) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0009011 |
| tracheobronchial serous cell (CL:0019001) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0019001 |
| kidney distal convoluted tubule epithelial cell (CL:1000849) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000849 |
| epithelial cell of nephron (CL:1000449) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000449 |
| endocardial cell (CL:0002350) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002350 |
| endothelial cell of lymphatic vessel (CL:0002138) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002138 |
| large intestine goblet cell (CL:1000320) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000320 |
| endothelial cell of vascular tree (CL:0002139) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002139 |
| cardiac endothelial cell (CL:0010008) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0010008 |
| obsolete somatic cell (CL:0002371) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002371 |
| urethra urothelial cell (CL:1001430) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1001430 |
| uterine smooth muscle cell (CL:0002601) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002601 |
| kidney afferent arteriole cell (CL:1001006) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1001006 |
| serous cell of epithelium of trachea (CL:1000330) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_1000330 |
| chorionic trophoblast cell (CL:0011101) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0011101 |
| embryonic cell (metazoa) (CL:0002321) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002321 |
| smooth muscle cell (CL:0000192) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000192 |
| cortical thymic epithelial cell (CL:0002364) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0002364 |
| melanocyte (CL:0000148) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000148 |
| middle primary motoneuron (CL:4042041) | oio:hasDbXref | ZFA:0005179 |
| bone cell (CL:0001035) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0001035 |
| cell of skeletal muscle (CL:0000188) | oio:hasDbXref | https://cellxgene.cziscience.com/cellguide/CL_0000188 |
Text definitions added: 58
| Term | New Text Definition |
|---|---|
| myotendinous junction nucleus (CL:4052024) | A specialized muscle nucleus that is part of an extrafusal muscle fiber and overlaps the muscle-tendon junction, where muscle fibers connect to tendons. Characterized by a distinct transcriptional profile with the expression of genes like COL22A1, this myonucleus supports the structural integrity and function of the junction, playing a key role in transmitting the force generated by muscle contraction to the tendon. |
| secretory pericyte (CL:4047032) | A specialized pericyte located within the basement membrane of a blood capillary. This cell is characterized by its ability to produce and release a variety of bioactive molecules, collectively known as the pericyte secretome, including cytokines and regulators of angiogenesis. |
| intestinal lamina propria fibroblast (CL:4047023) | A fibroblast located in the lamina propria of the intestinal mucosa. This cell expresses PDGFRα and CD81 and is negative for α-smooth muscle actin (α-SMA). This cell is predominantly located in the small intestine adjacent to myofibroblasts surrounding the crypts. It is capable of synthesizing extracellular matrix components and structural proteins such as collagen and elastin. |
| respiratory airway secretory cell (CL:4052031) | A secretory epithelial cell of the respiratory and terminal bronchioles. |
| neuromuscular junction nucleus (CL:4052025) | A specialized muscle nucleus that is part of an extrafusal muscle fiber, clustered at the postsynaptic side of the neuromuscular junction. This nucleus exhibits a distinct transcriptional profile, including acetylcholine receptor (AChR) subunit genes. It regulates the production of proteins essential for maintaining the structure and function of the neuromuscular junction, supporting efficient nerve-muscle signaling for muscle contraction. |
| type IIx muscle cell (CL:4052026) | A fast type II muscle cell that is part of the skeletal muscle tissue. This cell is characterized by its intermediate metabolic profile, utilizing both glycolytic and oxidative pathways for energy production. In humans, it is distinguished by the expression of myosin heavy chain 1 (MYH1). |
| lipid-associated macrophage (CL:4033086) | A tissue-resident macrophage that is associated with lipids. This cell responsible of anti-inflammatory functions, lipid accumulation and enhancing phagocytosis (Wculek et al., 2022, Liu et al., 2022). In mice and humans, a lipid-associated macrophage is characterized by the marker Trem2 (Jaitlin et al., 2019). |
| sst GABAergic neuron of the striatum (CL:4042037) | A interneuron of the striatum expressing gamma-aminobutyric acid and somatostatin. This interneuron has a fusiform soma with a diameter between 9 - 25 µm, it has a long axon up to the length of 1mm. This neuron type displays a low threshold Ca2+ spike (LTS), a high input resistance, and the expression of long-lasting plateau potentials following depolarization from rest. |
| choroid plexus capillary endothelial cell (CL:4052017) | A capillary endothelial cell that is part of the choroid plexus, characterized by its fenestrated nature with 60 to 80 nm fenestrations and lack of tight junctions. This fenestrated structure allows for the rapid delivery of water and other components, aiding in the production of cerebrospinal fluid (CSF). |
| lung resident granzyme K-associated CD8 T cell (CL:4052020) | A granzyme K-associated CD8 T cell that resides in the lung, characterized by the expression of granzyme K (GZMK), and tissue residency markers CD103 and CD49a. This cell exhibits cytotoxic potential through its expression of multiple granzymes (GZMA, GZMB, GZMH, GZMM) in addition to GZMK. |
| placental resident macrophage (CL:4033087) | A tissue-resident macrophage that is part of the placenta. This cell helps preventing immunological rejection of the fetus by modulating the immune environment. A placental resident macrophage has high plasticity to adapt to the changing needs of each phase of pregnancy. |
| glioblast (CL:0000030) | A non-terminally differentiated cell that develops form the neuroectoderm. Glioblast has the potential to differentiate into various types of glial cells, including astrocytes and oligodendrocytes. |
| subpleural fibroblast (CL:4052029) | A fibroblast that is located beneath the visceral pleura of the lung. This cell contributes to the development of idiopathic pulmonary fibrosis (IPF) by forming fibrotic lesions that originate subpleurally and extend into lung tissue through activation, proliferation, migration, and differentiation into a myofibroblast. |
| secretory epithelial cell (CL:1100001) | An epithelial cell that is specialised for the synthesis and secretion of specific biomolecules. |
| molecular layer interneuron (CL:4042035) | A type of cerebellar inhibitory GABAergic interneuron that is located in the molecular layer of the cerebellum. This cell type inhibits Purkinje cells and other molecular layer interneurons. This interneuron plays a crucial role in regulating cerebellar output through feedforward inhibition and is characterized by its fast-spiking properties. |
| glycinergic-GABAergic amacrine cell (CL:4033091) | An amacrine cell that uses both GABA and glycine as neurotransmitters. |
| caudal ganglionic eminence derived neuron (CL:4042039) | A neuron of the central nervous system that develops from a caudal ganglionic eminence. |
| transit amplifying cell of gut (CL:4047017) | A transit amplifying cell of the gut epithelium, located in the wall of the intestinal crypt, just above intestinal stem cells from which they derive. These are rapidly dividing cells, capable of multiple rounds of division before differentiating into the various cell types of the gut epithelium (enterocyte, goblet, eneterodendocrine, paneth cells). |
| pituitary gland capillary endothelial cell (CL:4052016) | A capillary endothelial cell that is part of the pituitary gland. This cell is characterized by its fenestrated structure which facilitates the efficient transport of hormones and other signaling molecules, essential for endocrine signalling. |
| pre-venule capillary cell (CL:4047030) | A specialized endothelial cell located in the transition zone between capillaries and small venules in the microvascular system. It exhibits characteristics of both capillary and venous cells, expressing markers from both types. This cell plays a role in regulating blood flow and substance exchange between blood and tissues. |
| type G cell of stomach (CL:4047025) | Any type G enteroendocrine cell that is part of some epithelium of stomach. |
| externa theca cell (CL:4052013) | A specialized theca cell that forms the outer layer of the theca surrounding the ovarian follicle, appearing at the antral follicle. Originating from progenitor theca cells, theca externa cell is characterized by its fibroblast-like appearance and primarily function to provide structural support to the developing follicle. This cell produces collagen fibers and extracellular matrix components such as Col1a1 and Col1a2. |
| CD57-positive enterocyte (CL:4033092) | An enterocyte that is part of a duodenal epithelium and expresses beta-1,3-glucuronyltransferase 1 (B3GAT1), also known as CD57 or HNK-1. |
| glutamatergic neuron of the basal ganglia (CL:4042040) | A glutametergic neuron with its soma located in a basal ganglia. This neuron type is involved in motor control, decision making and learning. |
| decidual resident macrophage (CL:4033088) | A resident macrophage that is part of the decidua. Some decidual macrophages are derived from maternal blood monocytes that are recruited to the uterus shortly after conception. The main functions of a decidual macrophage are implantation, placental development, immune regulation and vascular remodeling. |
| fallopian tube smooth muscle cell (CL:4052022) | A smooth muscle cell that is part of the fallopian tube. This cell is responsible for peristaltic contractions that facilitate gamete and embryo transport, fluid mixing, and embryo admission to the uterus. |
| uterine natural killer cell (CL:4052028) | A natural killer cell that is part of the uterus, specifically within the endometrium during the non-pregnant state and in the decidua during pregnancy. This cell exhibits dynamic changes in frequency throughout the menstrual cycle, with lower levels during menstruation and a significant increase during the mid-secretory phase and early pregnancy. |
| interna theca cell (CL:4052012) | A specialized theca cell that forms the inner, highly vascularized layer of the theca surrounding ovarian follicles. Originating from progenitor theca cells, the theca interna cell is steroidogenic, playing a crucial role in the production of androgens, which serves as a precursor for estrogen synthesis in granulosa cells. This cell expresses luteinizing hormone receptors, enabling it to respond to hormonal signals that regulate steroidogenesis. |
| columnar neuron (CL:0000112) | A neuron of the invertebrate central nervous system. This neuron innervates the central complex (CX) of an invertebrate brain and it forms columnar patterns with its dendrites. It is involved in navigation and spatial processing. |
| candelabrum cell (CL:4042030) | A GABAergic interneuron located in the cerebellar cortex. This GABAergic interneuron type has a distinct morphology, it presents a small cell soma near the Purkinje cell layer (PCL), dendrites that extend to the surface of the molecular layer, and beaded axons that make local synapses contacts within the molecular layer. A candelabrum cell is excited by mossy fibers and granule cells but inhibited by Purkinje cells, and it inhibits molecular layer interneurons, which leads to the disinhibition of Purkinje cells. |
| limbal epithelial stem cell of cornea (CL:4033093) | A stem cell that is part of the corneo-scleral limbus. This cell type resides at the basal layer of the epithelium and has a small size and high nuclear to cytoplasmatic ratio (Secker and Daniels, 2009). A limbal stem cell is responsible for corneal epithelial renewal and repair (Li et al., 2023), and to help maintain a clear corneal surface by preventing conjunctival epithelial cells from migrating onto the cornea (Wang et al., 2023). |
| immune oligodendroglia (CL:4042031) | An oligodendrocyte of the central nervous system that exhibits immune properties such as self-presentation and non-self antigen presentation to T cells, phagocytosis of debris, and cytokine and chemokine production. Immune oligodendroglia is immunoreactive during inflammation, neurodegenerative disorders, chronic stress and major depressive disorder. |
| atretic granulosa cell (CL:4033090) | A granulosa cell that is undergoing atresia. This cell type displays distinct morphological alterations compared with a healthy granulosa cell, including pyknosis (nuclear condensation) and cellular shrinkage. |
| fallopian tube non-ciliated cell (CL:4052019) | Any epithelial cell that is part of the fallopian tube and lacks cilia. |
| cortical immature neuron (CL:4042029) | An immature neuron of a cerebral cortex. This neuron develops prenatally and remains in an immature state throughout the lifespan of the organism. |
| CGRP-expressing neuron (CL:4042034) | An interneuron neuron characterized by the expression of calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide. This neuron type is involved in nociception and pain modulation by facilitating the transmission of nociceptive signals from peripheral sensory nerve endings to central nervous system structures. This neuron type is found in the dorsal root ganglia (DRG) and trigeminal ganglion, and the spinal cord dorsal horn. |
| luminal endometrial unciliated epithelial cell (CL:4052023) | An epithelial cell that is part of the endometrial luminal epithelium, forming a continuous layer lining the uterine cavity. This cell undergoes cyclical changes during the menstrual cycle, proliferating under estrogen in the proliferative phase, and differentiating under progesterone in the secretory phase to prepare for potential implantation. During the window of implantation, this cell changes from a tall columnar shape to a shorter columnar or cuboidal form, loses polarity, and becomes receptive to blastocyst implantation. |
| pancreatic islet capillary endothelial cell (CL:4052014) | A capillary endothelial cell that is part of islet of Langerhans, characterized by a high density of fenestrations —approximately ten times greater than those in exocrine pancreatic capillaries. These fenestrations facilitate efficient hormone exchange, which is essential for maintaining glucose homeostasis. The cell's structure and function are regulated by the local production of vascular endothelial growth factor-A (VEGF-A), which maintains its fenestrated architecture. |
| PAX6 GABAergic cortical interneuron (CL:4042032) | A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses the transcript PAX6. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: CGE-derived interneurons', Author Categories: 'CrossArea_subclass', clusters PAX6. |
| adventitial fibroblast (CL:4052030) | A fibroblast of the adventitia of a blood vessel. This cell contributes to vascular homeostasis, remodeling, and inflammation by producing extracellular matrix components, cytokines, and growth factors. Adventitial fibroblast can transition into an activated state during injury or disease, marked by increased proliferation, migration, matrix deposition, and contractile protein expression |
| commissural neuron (CL:0000678) | A neuron with soma location in the central nervous system that project its axon to the contralateral side of a central nervous system. This neuron can have its soma in the spinal cord, in the hemisphere of the brain, in the retina or in the ventral nerve cord of invertebrates. |
| post-arteriole capillary cell (CL:4047029) | An endothelial cell forming the walls of capillaries immediately downstream from arterioles, facilitating the exchange of substances between blood and interstitial fluid. This cell is characterized by a small diameter and may be continuous, fenestrated, or sinusoidal, depending on their location and function. This cell plays a crucial role in tissue oxygenation, nutrient delivery, and maintaining homeostasis within the microvascular network. |
| diffuse bipolar 5 cell (CL:4033085) | An ON diffuse bipolar cell that stratifies in the stratum 3 of the inner plexiform layer to make synapses with ON parasol ganglion cells. A diffuse bipolar 5 cell has high expression of MYO16 compared with other bipolar cells. |
| melanin-concentrating hormone neuron (CL:4042036) | A neuron of the central nervous system with its soma primarily located in the lateral hypothalamic area and surrounding regions, including the zona incerta. This neuron type expresses melanin-concentrating hormone and is involved in regulating various physiological processes, including sleep, feeding behavior, and energy homeostasis. |
| polymodal neuron (CL:0000102) | A neuron type that respond to multiple stimuli such as mechanical, thermal and chemical. This neuron type is responsible for integrating different types of sensory inputs, allowing organisms to respond appropriately to diverse environmental challenges. |
| atretic theca cell (CL:4052027) | A theca cell undergoing atresia, characterized by distinct morphological changes including hypertrophy, altered cell shape, and disrupted layered organization. This cell exhibits reduced steroidogenic capacity and changes in surrounding vascularization. The onset of theca cell atresia can vary, occurring at different stages of follicle atresia depending on the phase of folliculogenesis. |
| atretic follicular cell of ovary (CL:4033089) | A follicular cell of ovary that has begun to degenerate and undergo atresia, a specialized apoptosis. This cell is found in an atretic follicle, which is an ovarian follicle that started to mature but failed to reach full development and instead regresses. |
| rostral primary motorneuron (CL:4042038) | A type of primary motor neuron situated in the rostral region of the spinal cord. RoP neurons extend their axons to innervate the ventral trunk musculature. |
| immature neuron (CL:4042028) | A neuron in the central nervous system that is not committed to a differentiated fate, has not been newly derived from neurogenesis, and does not integrate into any circuit. |
| stomach smooth muscle outer longitudinal layer cell (CL:4047035) | A specialized smooth muscle cell located in the outermost layer of the muscularis externa of the stomach wall. This cell is arranged longitudinally along the stomach's axis and is responsible for the contractions that facilitate food movement toward the pylorus. |
| CAP motoneuron (CL:0000532) | A primary motor neuron with its soma in the caudal region of a spinal cord. The axon of this motoneuron exit the spinal cord from one single point and innervates the lateral surface of ventral axial muscles |
| liver-resident natural killer cell (CL:4047101) | A natural killer cell resident to the liver, located in the hepatic sinusoids. In humans this cell type is distinguished from circulating natural killer cells by CD49a or CD69 gene expression. Liver-resident natural killer cells have also been shown to express CCR5, EOMES, KLRB1, GZMK, and CXCR6 in humans. |
| granzyme K-associated CD8 T cell (CL:4052021) | A CD8 T cell characterized by high expression of Granzyme K (GZMK). This cell is enriched in both inflamed tissues, such as synovial tissue in rheumatoid arthritis and respiratory tissues during COVID-19, as well as non-inflamed tissues like the gut and kidneys. Unlike highly cytotoxic GZMB+ CD8+ T cell, GZMK+ CD8+ T cell exhibits lower direct cytotoxic potential, and is involved in producing pro-inflammatory cytokines such as IFN-γ and TNF-α. |
| middle primary motoneuron (CL:4042041) | A type of primary motor neuron located in the middle region of the spinal cord. This primary motor neuron type is characterized by their distinct axonal pathways that innervate the middle trunk muscles. |
| smooth muscle cell of stomach (CL:4047034) | A smooth muscle cell that is part of the muscularis externa of the stomach wall. It is characterized by its fusiform shape, involuntary control, and ability to generate slow, sustained contractions. This cell is organized in distinct layers and is essential for gastric motility and digestion. |
| endocrine gland capillary endothelial cell (CL:4052015) | Any capillary endothelial cell that is part of an endocrine gland. |
| pro-opiomelanocortin neuron (CL:4042033) | A neuron of the central nervous system that expresses POMC and synthesizes the POMC precursor polypeptide. This neuron type is located in the arcuate nucleus of the hypothalamus and in the nucleus tractus solitarius of the brainstem. The pro-opiomelanocortin neuron is part of the central melanocortin system and it is involved in regulating energy homeostasis, metabolism, and appetite. This neuronal type responds to hormonal signals such as levels of leptin and insulin, and its activation results in the release of α-melanocyte-stimulating hormone (α-MSH), which acts on melanocortin receptors to suppress food intake and increase energy expenditure. |
| fallopian tube epithelial cell (CL:4052018) | Any epithelial cell that is part of the fallopian tube. |
Nodes renamed: 45
| ID | Old Label | New Label |
|---|---|---|
| CL:0000997 | immature CD8_alpha-negative CD11b-positive dendritic cell | immature CD8-alpha-negative CD11b-positive dendritic cell |
| CL:1001590 | epididymis glandular cell | epididymis secretory cell |
| CL:0002455 | CD8_alpha-negative plasmacytoid dendritic cell | CD8-alpha-negative plasmacytoid dendritic cell |
| CL:0000402 | CNS interneuron | obsolete CNS interneuron |
| CL:1001589 | duodenum glandular cell | duodenum secretory cell |
| CL:0001018 | immature CD8_alpha-low Langerhans cell | immature CD8-alpha-low Langerhans cell |
| CL:1001591 | oviduct glandular cell | oviduct secretory cell |
| CL:0002059 | CD8alpha-positive thymic conventional dendritic cell | CD8-alpha-positive thymic conventional dendritic cell |
| CL:0001001 | immature CD8_alpha-negative CD11b-negative dendritic cell | immature CD8-alpha-negative CD11b-negative dendritic cell |
| CL:0001003 | mature CD8_alpha-negative CD11b-positive dendritic cell | mature CD8-alpha-negative CD11b-positive dendritic cell |
| CL:4030026 | BEST4+ enteroycte | BEST4+ enterocyte |
| CL:4030042 | glandular endometrial ciliated epithelial cell | glandular endometrial multiciliated epithelial cell |
| CL:0002145 | ciliated columnar cell of tracheobronchial tree | multiciliated columnar cell of tracheobronchial tree |
| CL:0005012 | multi-ciliated epithelial cell | multiciliated epithelial cell |
| CL:0002368 | respiratory epithelial cell | respiratory tract epithelial cell |
| CL:0002182 | surface mucosal cell of stomach | obsolete surface mucosal cell of stomach |
| CL:0002456 | CD8_alpha-positive plasmacytoid dendritic cell | CD8-alpha-positive plasmacytoid dendritic cell |
| CL:0002332 | ciliated cell of the bronchus | multiciliated epithelial cell of the bronchus |
| CL:1001598 | small intestine glandular cell | small intestine secretory cell |
| CL:0001020 | mature CD8_alpha-low Langerhans cell | mature CD8-alpha-low Langerhans cell |
| CL:4030034 | respiratory ciliated cell | respiratory tract multiciliated cell |
| CL:4030040 | endometrial ciliated epithelial cell | endometrial multiciliated epithelial cell |
| CL:0001004 | immature CD8_alpha-positive CD11b-negative dendritic cell | immature CD8-alpha-positive CD11b-negative dendritic cell |
| CL:0002656 | glandular cell of endometrium | glandular endometrial unciliated epithelial cell |
| CL:0000150 | glandular epithelial cell | glandular secretory epithelial cell |
| CL:0002370 | respiratory goblet cell | respiratory tract goblet cell |
| CL:1000223 | lung neuroendocrine cell | pulmonary neuroendocrine cell |
| CL:0001015 | CD8_alpha-low Langerhans cell | CD8-alpha-low Langerhans cell |
| CL:1001587 | uterine cervix glandular cell | uterine cervix secretory cell |
| CL:4030007 | fallopian tube ciliated cell | fallopian tube multiciliated cell |
| CL:0002454 | Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell | CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell |
| CL:4030041 | luminal endometrial ciliated epithelial cell | luminal endometrial multiciliated epithelial cell |
| CL:0002514 | Vgamma5-negative CD8alpha alpha positive gamma-delta intraepithelial T cell | Vgamma5-negative CD8-alpha alpha positive gamma-delta intraepithelial T cell |
| CL:0001005 | mature CD8_alpha-positive CD11b-negative dendritic cell | mature CD8-alpha-positive CD11b-negative dendritic cell |
| CL:0001000 | CD8_alpha-positive CD11b-negative dendritic cell | CD8-alpha-positive CD11b-negative dendritic cell |
| CL:4030023 | respiratory hillock cell | respiratory tract hillock cell |
| CL:0000317 | sebum secreting cell | sebocyte |
| CL:0001002 | mature CD8_alpha-negative CD11b-negative dendritic cell | mature CD8-alpha-negative CD11b-negative dendritic cell |
| CL:4033055 | airway submucosal gland duct ciliated cell | airway submucosal gland duct multiciliated cell |
| CL:0002140 | acinar cell of sebaceous gland | skin sebocyte |
| CL:0002460 | CD8alpha-negative thymic conventional dendritic cell | CD8-alpha-negative thymic conventional dendritic cell |
| CL:0002513 | Vgamma5-positive CD8alpha alpha positive gamma-delta intraepithelial T cell | Vgamma5-positive CD8-alpha alpha positive gamma-delta intraepithelial T cell |
| CL:4033048 | respiratory suprabasal cell | respiratory tract suprabasal cell |
| CL:0000998 | CD8_alpha-negative CD11b-negative dendritic cell | CD8-alpha-negative CD11b-negative dendritic cell |
| CL:1000271 | lung ciliated cell | lung multiciliated epithelial cell |
Synonyms removed: 9
| Term | Removed Synonym |
|---|---|
| small intestine secretory cell (CL:1001598) | small intestinal glandular cell |
| respiratory tract hillock cell (CL:4030023) | hillock cell of respiratory tract |
| sebocyte (CL:0000317) | sebocyte |
| pulmonary neuroendocrine cell (CL:1000223) | pulmonary neuroendocrine cell |
| skin sebocyte (CL:0002140) | sebocyte |
| epididymis secretory cell (CL:1001590) | epididymis glandular cells |
| duodenum secretory cell (CL:1001589) | duodenum glandular cells |
| columnar neuron (CL:0000112) | columnar neuron |
| colonocyte (CL:1000347) | colonocyte |
Mappings removed: 1
| Subject | Predicate | Object |
|---|---|---|
| obsolete CNS interneuron (CL:0000402) | oio:hasDbXref | ZFA:0009191 |
Nodes obsoleted with replacement: 2
| Term | Replacement |
|---|---|
| obsolete surface mucosal cell of stomach (CL:0002182) | foveolar cell of stomach (CL:0002179) |
| obsolete CNS interneuron (CL:0000402) | interneuron (CL:0000099) |
What's Changed
- NTR liver resident NK cells by @JABelfiore in #2472
- Fixes #2528 - NTRs - externa and interna theca cells by @Caroline-99 in #2622
- Fixes #2623 Fixes #2624 NTRs and revise classifications- fallopian tube epithelial cell and subclasses by @Caroline-99 in #2631
- Fixes #2485 NTR - pancreatic islet capillary endothelial cell by @Caroline-99 in #2625
- Fixes #2630 Use hyphens for immune cells by @aleixpuigb in #2632
- Fixes #2627 Revise logical definition of 'inflammatory macrophage' by @aleixpuigb in #2633
- Fibroblasts are stromal by @dosumis in #2571
- Fixes #2486 Fixes #2484 NTR- endocrine gland and pituitary gland capillary endothelial cell by @Caroline-99 in #2628
- Fixes #2481 NTR- choroid plexus capillary endothelial cell by @Caroline-99 in #2629
- Cleanup custom makefile by @gouttegd in #2645
- glandular epithelial cell refactor option 2 by @dosumis in #2452
- NTR]-Immune-oligodendroglia-and-basal-ganglia-terms by @AvolaAmg in #2642
- Update monthly call times in README by @aleixpuigb in #2667
- [NTR] Pax6 GABAergic cortical interneuron by @AvolaAmg in #2643
- Fixes #2646 NTR-lung resident granzyme k-associated CD8 T cell by @Caroline-99 in #2648
- Fixes #2682 NTR - fallopian smooth muscle cell by @Caroline-99 in #2684
- Fixes #2687 NTR- luminal endometrial unciliated epithelial cell by @Caroline-99 in #2689
- Fixes #2240 NTR lipid associated macrophage by @aleixpuigb in #2666
- Fixes #2672 - textual and logical defs - parietal cell by @Caroline-99 in #2681
- Fixes #2670 logical and textual defs - peptic cell by @Caroline-99 in #2680
- NTR Immature neurons and immature cortical neurons by @AvolaAmg in #2635
- Move terms under [peripheral nervous system neuron] by @AvolaAmg in #2665
- NTR candelabrum cell by @AvolaAmg in #2650
- Fixes #2516 Glioblast textual definition by @Caroline-99 in #2696
- text def stomach neuroendocrine cell by @JABelfiore in #2691
- Fixes #2651 NTR diffuse bipolar 5 cell by @aleixpuigb in #2664
- Fixes #2695 #2468 Re-labelled glandular cell of endometrium and improved classifications by @Caroline-99 in #2697
- Fixes #2409 Stomach neuroendocrine cells now classified under grouping term by @JABelfiore in #2533
- Fixes #2700 remove colonocyte synonym by @aleixpuigb in #2701
- move terms under central nervous system neuron by @AvolaAmg in #2663
- Break down SubClassOf axioms with an intersection as the superclass. by @gouttegd in #2703
- Fixes #2704 - Revise classification of intestinal crypt stem cell of large intestine and subclasses by @Caroline-99 in #2709
- Fixes #2678 - NTR - neuromuscular junction nucleus by @Caroline-99 in #2714
- Fixes #2706 -Logical defs for large intestine goblet cell and small intestine goblet cell (+Subclasses) by @Caroline-99 in #2716
- [NTR] CGRP-expressing neuron by @AvolaAmg in #2712
- NTR-pro-opiomelanocortin-neuron by @AvolaAmg in #2649
- Compute diff on -base rather than -simple. by @gouttegd in #2724
- Fixes #2707 - Logical and textual defs acinar cell of sebaceous gland by @Caroline-99 in #2711
- NTR intestinal lamina propria fibroblast by @JABelfiore in #2611
- Add-text-definition-to-peripheral-sensory-neuron,-polymodal-neuron,-c… by @AvolaAmg in #2710
- FIxes #2676 myotendinous junction nucleus by @Caroline-99 in #2713
- Fixes #2694 NTR placental resident macrophages by @aleixpuigb in #2715
- Transit amplifying cell of gut by @JABelfiore in #2603
- Switch to Whelk reasoner by @gouttegd in #2722
- Fixes #2728 NTR atretic follicular cell of ovary by @aleixpuigb in #2730
- Fixes #2732 ntr cxg atretic theca cell by @Caroline-99 in #2733
- Fixing lung multiciliated cell heirarchy by @dosumis in #2735
- pre-venule capillary cell by @JABelfiore in #2738
- Fixes #2652 - Added GO terms for colonocytes + Updated definition by @Caroline-99 in #2741
- Fixes #2705 Textual and logical defs - ureter and urethra urothelial cell by @Caroline-99 in #2734
- NTR-Melanin-concetrating-hormone-neuron-and-Molecular-layer-interneuron by @AvolaAmg in #2720
- Fixes #2673 NTR CxG type IIx muscle cell by @aleixpuigb in #2731
- Remove hasAlternativeID for FMA:83808. by @gouttegd in #2746
- Add ID format check by @gouttegd in #2747
- Update foreign SSSOM set from ontology by @gouttegd in #2748
- post-arteriole capillary cell by @JABelfiore in #2736
- adjust-the-hierarchy-CNS-nematoda-and-CNS-vertebrata by @AvolaAmg in #2745
- Fixes #2755 BEST4+ enterocyte typo by @Caroline-99 in #2757
- secretory pericyte by @JABelfiore in #2740
- NTR-grouping-term-caudal-ganglionic-eminence-derived-neuron by @AvolaAmg in #2758
- Fixes #2774 - Added GO links to deuterosomal cell by @Caroline-99 in #2777
- Fixes#2688 NTR- uterine natural killer cell by @Caroline-99 in #2765
- Fixes #2784 - Improve stromal cell of endometrium by @Caroline-99 in #2789
- Fixes #2775 rename lung neuroendocrine cell by @Caroline-99 in #2790
- NTR-glutametergic-neuron-of-the-basal-ganglia by @AvolaAmg in #2773
- Add taxon subsets by @gouttegd in #2811
- 2464 gut epithelial cells by @JABelfiore in #2750
- NTR-SST-GABAergic-neuron-of-the-striatum by @AvolaAmg in #2812
- NTR-glutamatergic-neuron-of-the-thalamus by @AvolaAmg in #2798
- SI images added by @JABelfiore in #2794
- CL images by @JABelfiore in #2814
- 2725 Add CellMark CLM-CL component by @gouttegd in #2772
- Fixes #2675 Added developmental lineages for intestinal epithelial cells by @Caroline-99 in #2762
- Fixes #2793 - respiratory tract multiciliated cell by @Caroline-99 in #2817
- Fixes #2780 - NTR- subpleural fibroblast by @Caroline-99 in #2820
- harmonising respiratory tract and MCC names by @dosumis in #2796
- Fixes #2818 NTR GABA-Gly AC by @aleixpuigb in #2823
- Fixes #2770 - textual and logical -brush cell of tracheobronchial tree by @Caroline-99 in #2821
- 2839 ntr smooth muscle cell of stomach by @JABelfiore in #2840
- Fixes #2776 - respiratory suprabasal cell textual definition by @Caroline-99 in #2819
- Fixes #2778 NTR- adventitial fibroblast by @Caroline-99 in #2841
- Fixes #2845 - Adding approved CellGuide defs by @Caroline-99 in #2848
- separating_gut_meosthelial_from_gut_lining by @dosumis in #2674
- Add ID range for the NDI Cloud project. by @gouttegd in #2859
- Fix some uncaught violations by @gouttegd in #2854
- Fixes #2851 typo bug in LLM-generated definitions by @Caroline-99 in #2862
- Customise OBO products by @gouttegd in #2860
- Fixes #2855 NTR limbal epithelial stem cell by @aleixpuigb in #2857
- Merge cns interneuron interneuron term by @AvolaAmg in #2686
- Fixes #2749 NTR- Respiratory airway secretory cell by @Caroline-99 in #2867
- Addresses #2786 NTR CD57-positive enterocyte by @aleixpuigb in #2847
- Fixes 2869 wrongly obsoleted 'CNS interneuron' by @aleixpuigb in #2870
- Fix the ID range allocated to Whitney Leach. by @gouttegd in #2871
- Adjust hierarchy of somatosensory neurons (sensu Teleostei) by @AvolaAmg in #2751
- stomach smooth muscle outer longitudinal layer cell by @JABelfiore in #2846
- Refresh imports in preparation of release v2024-12-23 by @aleixpuigb in #2868
- Release v2025-01-08 by @aleixpuigb in #2878
Full Changelog: v2024-09-26...v2025-01-08
Contributors
dosumis, gouttegd, and 4 other contributors