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Merge pull request #142 from maxulysse/fix_dbsnp_known_indels_usage
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Fix dbsnp usage
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maxulysse authored May 31, 2024
2 parents 48cb638 + 358c6ff commit 4e9fb0e
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1 change: 1 addition & 0 deletions CHANGELOG.md
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Expand Up @@ -28,6 +28,7 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
- [#132](https://github.com/nf-core/rnavar/pull/132) - Added missing variantcaller key to meta map, to fix null value in publishDir
- [#136](https://github.com/nf-core/rnavar/pull/136) - Replaced unzip module with gunzip, removed unzip module
- [#138](https://github.com/nf-core/rnavar/pull/138) - Proper usage of GVCF
- [#142](https://github.com/nf-core/rnavar/pull/142) - Fix dbsnp channels

### Dependencies

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11 changes: 7 additions & 4 deletions workflows/rnavar/main.nf
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Expand Up @@ -253,8 +253,11 @@ workflow RNAVAR {
interval_flag = params.no_intervals
// Run haplotyper even in the absence of dbSNP files
if (!params.dbsnp){
ch_dbsnp = []
ch_dbsnp_tbi = []
ch_dbsnp_for_haplotypecaller = [[id:'null'], []]
ch_dbsnp_for_haplotypecaller_tbi = [[id:'null'], []]
} else {
ch_dbsnp_for_haplotypecaller = ch_dbsnp.map{ vcf -> [[id:'dbsnp'], vcf] }
ch_dbsnp_for_haplotypecaller_tbi = ch_dbsnp_tbi.map{ tbi -> [[id:'dbsnp'], tbi] }
}

ch_haplotypecaller_vcf = Channel.empty()
Expand All @@ -273,8 +276,8 @@ workflow RNAVAR {
ch_fasta,
ch_fasta_fai.map{ it -> [[id:it.baseName], it] },
ch_dict,
ch_dbsnp.map{ it -> [[id:it.baseName], it] },
ch_dbsnp_tbi.map{ it -> [[id:it.baseName], it] }
ch_dbsnp_for_haplotypecaller,
ch_dbsnp_for_haplotypecaller_tbi
)

ch_haplotypecaller_raw = GATK4_HAPLOTYPECALLER.out.vcf.map{ meta, vcf -> [ meta + [id:meta.sample] - meta.subMap('sample'), vcf ] }.groupTuple()
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