Single-MITOchondrion (SMITO) Data Analysis Scripts

Overview

This repository contains code for SMITO data analysis. For SMITO computational pipeline, see smito-pipeline.

Author

Youtao Lu ([email protected])

Copyright

Copyright (c) 2021-2023, Youtao Lu, Erik Nordgren, Stephen Fisher and Junhyong Kim, Department of Biology, University of Pennsylvania
Copyright (c) 2021-2023, Parnika Kadam, Hua Zhu and James Eberwine, Perelman School of Medicine, University of Pennsylvania
Copyright (c) 2021-2023, Zijian Yang, Yasemin Atiyas, Nishal Shah and David Issadore, Penn Engineering, University of Pennsylvania

License

Creative Commons Attribution License 4.0 (CC BY)

Reference

• Parnika Kadam, Zijian Yang, Youtao Lu, Hua Zhu, Yasemin Atiyas, Nishal Shah, Stephen Fisher, Erik Nordgren, Junhyong Kim, David Issadore and James Eberwine. "Single-Mitochondrion Sequencing Uncovers Distinct Mutational Patterns and Heteroplasmy Landscape in Mouse Astrocytes and Neurons" (BMC Biology 22, 162 (2024))

Erratum

• We cited circlize by the Research Resource Identifier (RRID:SCR_002141) but forgot to cite the original publication: Gu, Zuguang, Lei Gu, Roland Eils, Matthias Schlesner, and Benedikt Brors. "Circlize Implements and Enhances Circular Visualization in R" (Bioinformatics 30(19), 2811–2812 (2014)) per authors' instruction in the software startup message. We apologize for the oversight.
• In Figure 1B, the mitochondrion and the mouse icons were designed by Freepik and obtained from Flaticon; the neuron icon was designed by Nadiinko and obtained from Flaticon. We apologize for the missing attributions in our publication.