analise_de_dados_curso

Repositório destinado à realização das listas de exercícios e do projeto final referente à disciplina RBP5802 - Introdução à ciência dos dados.

Final Project

Processing and Visualizing Proteomics Data With Python

Part 1: Analysis of Mass Spectrometry Data Using Python Tools

Check scripts 01, 02, and 03.

Part 2: Prediction of Alternative Open Reading Frames (Alt-ORFs) in a model breast cancer cell line (MCF7)

Genome Retrieval and Processing

Genome:Ben-David, U., Siranosian, B., Ha, G. et al. Genetic and transcriptional evolution alters cancer cell line drug response. Nature 560, 325–330 (2018). https://doi.org/10.1038/s41586-018-0409-3 - BioProject PRJNA398960; MCF7-scWT5-TS (SRR6730014) Check script 04.

Predicting Alt-ORFs

Check script 05.

Processing ORFs output

• Translating nucleic acid sequences from Alt-ORFs to amino acid sequences to re-do Fragpipe analysis using MCF7 annotated genome with Alt-ORFs Check script 06.