Releases: haotianteng/Chiron
Bug fix for better RNA basecall performance
Add the description in the README about the dependent package.
Add tf version
Remove unused package
Change the signal normalization to MEAN for better performance.
Faster RNA+DNA model with high accuracy
Release v0.6
Improvement
A new RNA model with overall >85% accuracy.
Obtain >60% successful short RNA reads basecall pass rate when using BoostNano for preprocess. (from <20% successful short RNA reads pass rate of other basecallers).
Bug fix and remake the DNA model.
This is a new version with a faster DNA model(10X faster and same accuracy) and pipeline optimization.
Chiron-v0.5
Update a new RNA model.
10X faster RNA inferencing.
Bug fix and human benchmark result update
Fix a bug that could cause the CTC decoding pipline stuck, replace tqdm module in chiron_eval.py with a self-written progress bar which is more stable(and almost equally fancy).
Improvement of the new model(DNA_default) on NA12878-WGS(human) benchmark dataset:
SUMMARY
Total reads:6080
Unaligned reads:3303 -> 1553
Deletion rate : 0.0930 -> 0.0847
Insertion rate : 0.0562 -> 0.0538
Mismatch rate : 0.0933 -> 0.0670
Identity rate : 0.8283 -> 0.8483
tqdm bug fix, and chiron_label added
Remove the tqdm process bar inside the worker, which cause Chiron collapsed. And fix the description of the process bar.
New feature released: chiron_label.py
Enable label(re-squiggle) the DNA/RNA reads with a high success rate, label reads can be used to train new Chiron model.
Chiron-0.4
Enable different model configuration specified by the config Json file.
Added a pre-trained RNN model (-200 mV, test version)
~3X faster basecalling when using GPU.
Enable cloud training using Google Cloud ML Engine.
Enable distributed training process, support multiple GPU training.
Chiron 0.3
New option added --beam <beam_width>
Default now using a beam search decoder with a beam width 50, set beam_width to 0 to use the previous greedy decoder.
Beam search decoder greatly reduced the deletion rate.
Chiron 0.2
train and export sub command, bug fixed.
Chiron 0.1.4
Add fastq output, and provide the quality score output.