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36 changes: 30 additions & 6 deletions README.md
Original file line number Diff line number Diff line change
Expand Up @@ -2,9 +2,29 @@
<img src="https://user-images.githubusercontent.com/41301333/195215088-8404f200-8297-4322-a30f-c84f526aa620.png" width="200" height="200" align="right">

### Table of Contents
1. [VariantSurvival](#variantsurvival)
2. [The shiny app](#the-shiny-app)
3. [The developers team](#the-developers-team)
1. [About](#About)
2. [VariantSurvival](#variantsurvival)
3. [The shiny app](#the-shiny-app)
4. [The developers team](#the-developers-team)
<br>


## About
VariantSurvival is a tool to identify genotype-treatment response in neurological disseaes
<br>
List of currently supported neurological disorders syndroms:

- Amyotrophic Lateral Sclerosis Spectrum Disorders
- Brain Malformations
- Cerebral Palsy
- Craniofacial Malformations
- Epilepsy
- Glaucoma and Neuro-Ophthalmology
- Intellectual Disability and Autism
- Leigh syndrome
- Parkinson disease
- Rett and Angelman-like Disorders
- Charcot-Marie-Tooth
<br>


Expand All @@ -26,10 +46,16 @@ The package can be installed in R studio using the following command:
```
#install.packages('devtools') #install devtools package
library(devtools)
devtools::install_github("collaborativebioinformatics/VariantSurvival/VariantSurvival_package")
devtools::install_github("collaborativebioinformatics/VariantSurvival/variantsurvival")
```
Note: All required packages will be installed automatically when installing "VariantSurvival".

### Demonstration
```
VariantSurvival::VariantSurvival(demo="TRUE")
```



### Running your data analysis
* WIP: what input to load into VariantSurvival: [VCF file](https://github.com/collaborativebioinformatics/VariantSurvival/blob/main/docs/preprocessing/prepareVCF.md), study groups metadata
Expand All @@ -42,8 +68,6 @@ VariantSurvival::VariantSurvival(vcffile="variant_file_.vcf", metadatafile= "met
```




## The developers team

* Ahmad Al Khleifat [![Twitter URL](https://img.shields.io/twitter/url/https/twitter.com/AhmadAlKhleifat.svg?style=social&label=Follow%20%40AhmadAlKhleifat)](https://twitter.com/AhmadAlKhleifat)
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15 changes: 0 additions & 15 deletions Refrences.txt

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