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Scripts for analytical mutation-selection-drift balance results presented in Wade et al 2022

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lethals_scripts

Scripts for analytical mutation-selection-drift balance results presented in Wade et al 2022.

plot_lethals.r generates Figure 7 plotting MSB predictions for humans and D. melanogaster based on available parameter estimates.

human_lethals_sim_030222.slim is a SLiM script for simulating recessive lethals under a non-equilibrium human demographic model (Jouganous et al. 2017 https://doi.org/10.1534/genetics.117.200493)

plot_simulation_results.R is for plotting simulation results in comparison with MSB model predictions.

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