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Workaround for issue #2 #3
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Original file line number | Diff line number | Diff line change |
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@@ -88,16 +88,40 @@ public SampleReport(String name, int index) { | |
*/ | ||
public void addVariant(VariantContext vc, VariantAnnotations va) { | ||
Genotype gt = vc.getGenotype(this.idx); | ||
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if (gt.isNoCall()) { // ./. => skip statistics and count missing value. | ||
this.n_missing++; | ||
return; | ||
} else if (gt.isHomRef()) // 0/0 => skip statistics. Ref genotype. Computation Ti/TV etc. is not needed. | ||
return; | ||
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// 1/1, 2/2, 0/1 and 1/2 we have to check if it is the same VarantAnnotation. | ||
// But 1/2 we have to count twice. So the easiest way will be to check if one alternative allele of gt is va.getAlt; | ||
There was a problem hiding this comment. Choose a reason for hiding this commentThe reason will be displayed to describe this comment to others. Learn more. I had to put this upwards |
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boolean foundAltAllele = false; | ||
for (Allele allele : gt.getAlleles()) { | ||
if (allele.isReference()) | ||
continue; | ||
if (allele.getBaseString().equals(va.getAlt())) { | ||
foundAltAllele = true; | ||
break; | ||
} | ||
} | ||
//skip | ||
if (!foundAltAllele) | ||
return; | ||
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There was a problem hiding this comment. Choose a reason for hiding this commentThe reason will be displayed to describe this comment to others. Learn more. check 2 |
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Annotation anno = va.getHighestImpactAnnotation(); // only highest-impact one | ||
if (anno == null) { | ||
System.err.println("[WARNING] No annotation found for variant " + vc); | ||
return; // no annotation | ||
} | ||
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if (gt.isNoCall()) { | ||
this.n_missing++; | ||
return; | ||
} | ||
if (gt.isHomVar()) | ||
this.n_homozygous++; | ||
else if (gt.isHet()) // 0/1, 1/2,... | ||
this.n_heterozygous++; | ||
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// To get the allelic depth | ||
// gt.getAF getAD | ||
//public abstract int[] getAD() | ||
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@@ -113,10 +137,7 @@ public void addVariant(VariantContext vc, VariantAnnotations va) { | |
} | ||
} | ||
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if (gt.isHomVar()) | ||
this.n_homozygous++; | ||
else if (gt.isHet()) | ||
this.n_heterozygous++; | ||
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String ref=va.getRef(); | ||
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check 1