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Merge pull request #54 from YeoLab/ekofman-patch-1
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ekofman authored Dec 11, 2024
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# Introduction

RNA editing is a widespread mechanism that drives transcriptomic diversity and influences cellular differentiation and function. Despite its importance, existing tools are inefficient for comprehensive analysis of RNA editing in single-cell datasets. We introduce MARINE (Multi-Core Algorithm for Rapid Identification of Nucleotide Edits), a powerful and efficient tool for mapping the RNA editing landscape at single-cell resolution.
RNA editing is a widespread phenomenon that drives transcriptomic diversity and influences cellular differentiation and function. Despite its importance, existing tools are inefficient for comprehensive analysis of RNA editing in single-cell datasets. We introduce MARINE (Multi-Core Algorithm for Rapid Identification of Nucleotide Edits), a powerful and efficient tool for mapping the RNA editing landscape at single-cell resolution.

Overview:
![MARINE overview](images/MARINE_workflow.png)

Speed and memory profiles:
![MARINE specs](images/MARINE_specs.png)

# Installation
Simply git clone this repository using the link at the top right on the main repository page. Should take at most a minute or two.
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