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pburnsdata authored Oct 13, 2024
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# nepExplorer

### Interactive Visual Kidney Function Data Exploration in Clinical Trials

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## Interactive Visual Kidney Function Data Exploration in Clinical Trials

## Summary

### Summary

The ASA Biopharmaceutical Working Group's [taskforce on Interactive Safety Graphics](https://safetygraphics.github.io/) has developed an open-source, interactive graphical tool to allow safety professionals to easily explore clinical trial laboratory data in order to identify instances of acute declines in renal function. "Drill down" capabilities provide a means to evaluate subject level data. The tool is accompanied by a comprehensive "clinical workflow" that guides the user through a series of evaluations each with a textual discussion regarding the goal of the evaluation step and the relevance of any findings with references to the supporting nephrology literature.

## Using the App
### Installation
nepExplorer is not available on CRAN yet. You can install the package from GitHub:
`devtools::install_github('safetyGraphics/nepExplorer', ref = 'main')`

### Using the App

nepExplorer was built using the safetyGraphics framework and uses a settings object to map fields from input data sets to chart aesthetics and configuration options. A demo of the app is available [here](https://sb75h1-preston0burns.shinyapps.io/nep-explorer/).

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