This release contains the OSP PBPK substance model library.
All models are published as a PK-Sim project model file along with a model evaluation report.
The project model files and evaluation reports of this release are created with OSP 11 Update 3 and are available here.
Release Notes
Notes are listed below for new or updated model files/evaluation reports. All other model files/evaluation reports are unchanged compared to the previous release.
New models
7E3
Added based on version 1.0. See the release notes for 7E3 v. 1.0 for details
BAY794620
Added based on version 1.0. See the release notes for BAY794620 v. 1.0 for details
CDA1
Added based on version 1.0. See the release notes for CDA1 v. 1.0 for details
dAb2
Added based on version 1.0. See the release notes for dAb2 v. 1.0 for details
Digoxin
Added based on version 2.0. See the release notes for Digoxin v. 2.0 for details
Inulin
Added based on version 1.0. See the release notes for Inulin v. 1.0 for details
MEDI524
Added based on version 1.0. See the release notes for MEDI524 v. 1.0 for details
MEDI524YTE
Added based on version 1.0. See the release notes for MEDI524YTE v. 1.0 for details
Tefibazumab
Added based on version 1.0. See the release notes for Tefibazumab v. 1.0 for details
Updates
Verapamil
Updated based on version 2.0. See the release notes for Verapamil v. 2.0 for details