Skip to content

Ion Homeostasis in Spatially Polarized Excitable Cells: An Approach to Maximize Endogenous Electric Fields

Notifications You must be signed in to change notification settings

MaxPiatine/biophysics

Folders and files

NameName
Last commit message
Last commit date

Latest commit

 

History

3 Commits
 
 
 
 
 
 
 
 
 
 
 
 

Repository files navigation

uOttawa PHY6999

Abstract

Understanding the dynamics of ion flux and polarization in spatially polarized excitable cells is crucial for fundamental physiological processes such as wound healing, muscle contraction, and nerve impulse transmission. This study investigates a charge difference model as a two-compartmentalized cell connected by a gap junction. Through theoretical analyses and simulations, we explore the result of symmetry breaking by manipulating ion permeability ratios and elongating the cell on endogenous electric fields. Our findings reveal that symmetry breaking can significantly enhance endogenous electric field strength while staying within realistic constraints. Our results provide valuable insights into cellular polarization mechanisms and offer implications for future research in cell physiology.

1dcell

Script

  • Endogenous.py script, contributed by Ziyi Liu's, is the original version of main.py and ratio.py.
python3 main.py

About

Ion Homeostasis in Spatially Polarized Excitable Cells: An Approach to Maximize Endogenous Electric Fields

Topics

Resources

Stars

Watchers

Forks

Releases

No releases published

Packages

No packages published

Languages