add "note"

docs/2_Theoretical_background/Ne-500.md

@@ -29,7 +29,7 @@ Thus, this indicator is directly relevant to **Goal A**, as it informs the healt
 
 As noted by [Hoban et al (2023a)](https://link.springer.com/article/10.1007/s10592-022-01492-0), the Ne 500 indicator is relevant to other targets such as sustainable harvest **Targets 5 and 9** because harvested populations should be maintained at or above Ne 500. To ensure all genetically distinct populations are represented at sufficient sizes to maintain their persistence, it is relevant for **Targets 1 and 3** on biodiversity inclusive spatial planning and representative protected areas, respectively, and **Target 12** for increasing area and connectivity of green and blue spaces in urban environments to promote gene flow and species recovery. 
 
-Note: the Ne 500 indicator is relevant for genetic diversity within populations and a separate indicator (i.e. complementary indicator for Goal A the “proportion of populations maintained”) is necessary for maintaining genetic diversity among populations. **Experts agree that both indicators are critical for assessing and monitoring the genetic health of species** (Hoban et al 2020, Hoban et al 2023b).
+{: .note } the Ne 500 indicator is relevant for genetic diversity within populations and a separate indicator (i.e. complementary indicator for Goal A the “proportion of populations maintained”) is necessary for maintaining genetic diversity among populations. **Experts agree that both indicators are critical for assessing and monitoring the genetic health of species** (Hoban et al 2020, Hoban et al 2023b).
 
 The indicator should be reported for 100+ representative species per country.  It is calculated by taking each population of a species, determining if each population is above the threshold of Ne 500, calculating a proportion of populations above the threshold for each species, and then taking a mean of these proportions across all species examined, as explained in [Hoban et al (2023b)](https://doi.org/10.1111/conl.12953) and [Hoban et al (2023c)](https://doi.org/10.32942/X2QK5W). As explained in that publication which contains the basic equations for calculation, the indicator can be weighted by taxonomic groups or other categories to offset any biases in the species selected (e.g. due to having more birds, more rare species etc.).