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Data and analysis of Diorhabda populaiton structure using RADseq

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Diorhaba Population Structure

Data and analysis of Diorhabda population structure using RADseq and a de novo reference genome.

Manuscript in prep!

Goals are to

  • Quantify prevalence and levels of hybridization among the four introduced species and source populations.
  • Examine the consequences of population bottlenecks and admixture on genome-wide diversity across broad, landscape-wide expansion fronts and the hybrid zone.

Most work was performed on the IBEST cluster, usually crick or watson.

What I did

  1. Assembled de novo Diorhabda carinulata reference genome, combining shotgun scaffolds assembled in Spades with in-silico 'linked' 10X reads.
  • raw reads for shotgun
  • raw reads for 10X
  • spades assembly
  • LINK/Arcs pipeline
  • BUSCO and QUAST assessment
  1. Generated SNPs across lots of individuals and populations (raw2vcftask.sh)
  • raw reads
  • clone_filtered
  • process_radtags
  • aligned to reference
  • gstacks
  • populations
  1. Model-based ancestry assignment in Structure
  • downloaded vcf to local computer
  • converted vcf to structure format with PGDspider
  • uploaded this back to cluster
  • ran K= 1-10 for 10 reps each
  • Re-ran this for carinulata and elongata to examine population substructure
  1. Examined population genetics in the context of hybridization
  • Popgen stats
  • Isolation by distance
  • RangeExpansion analysis on carinulata

To-do

  • upload scripts for genome assembly
  • upload raw data for genome assembly
  • upload raw data for population genetics
  • associate each of the steps above with scripts and directories

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Data and analysis of Diorhabda populaiton structure using RADseq

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