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Update README.md
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jluebeck committed Jun 19, 2023
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Expand Up @@ -144,15 +144,14 @@ Other arguments
- `--add_chr_tag`: If you have a mix of hg19 and GRCh37 amplicons, you can set `--ref hg19` and `--add_chr_tag` to classify them all together.
- `--min_flow`: Minumum cycle CN flow to consider among decomposed paths (default=1).
- `--min_size`: Minimum cycle size (in bp) to consider as valid amplicon (default=5000).
- `--report_comlexity`: Report a measurement of the amplicon's 'complexity' score, which represents a measurement of the complexity of the AA breakpoint graph decomposition.
- `--verbose_classification`: Output verbose information in the `amplicon_classification_profiles.tsv` file, and create `edge_classification_profiles.tsv`. Useful for debugging.
- `--force`: Disable No amp/Invalid class, if possible. Use only when extremely large CN seeds were used in AA amplicon generation (>10 Mbp intervals).
- `--plotstyle [noplot, individual]`: Produce a radar-style plot of classification strengths. Default `noplot`.
- `--decomposition_strictness`: Value between 0 and 1 reflecting how strictly to filter low CN decompositions (default = 0.1). Higher values filter more of the low-weight decompositions.
- `--exclude_bed`: Provide a bed file of regions to ignore during classification. Useful for separating linked amplicons or augmenting low-complexity annotations.
- `--no_LC_filter`: Set this to turn off filtering low-complexity & poor mappability genome region paths & cycles.
- `--no_LC_filter`: Set this to turn off filtering low-complexity & poor mappability genome region paths & cycles.
- `"--filter_similar`: Only use if all samples are of independent origins (not replicates and not multi-region biopsies). Permits filtering of false-positive amps arising in multiple independent samples based on similarity calculation.
- `--filter_similar`: Only use if all samples are of independent origins (not replicates and not multi-region biopsies). Permits filtering of false-positive amps arising in multiple independent samples based on similarity calculation.

### 5. Other utilities:

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