diff --git a/py3-cassandra-medusa.yaml b/py3-cassandra-medusa.yaml
index d0a15fd1197..46c04d93329 100644
--- a/py3-cassandra-medusa.yaml
+++ b/py3-cassandra-medusa.yaml
@@ -2,7 +2,7 @@
 package:
   name: py3-cassandra-medusa
   version: 0.22.3
-  epoch: 1
+  epoch: 2
   description: Apache Cassandra backup and restore tool
   copyright:
     - license: Apache-2.0
@@ -11,19 +11,41 @@ package:
     no-depends: true
   dependencies:
     runtime:
-      - poetry
-      - python-3.11-base
+      - py${{vars.py-version}}-aiohttp
+      - py${{vars.py-version}}-azure-identity
+      - py${{vars.py-version}}-azure-storage-blob
+      - py${{vars.py-version}}-boto3
+      - py${{vars.py-version}}-cassandra-driver
+      - py${{vars.py-version}}-click
+      - py${{vars.py-version}}-click-aliases
+      - py${{vars.py-version}}-certifi
+      - py${{vars.py-version}}-cryptography
+      - py${{vars.py-version}}-datadog
+      - py${{vars.py-version}}-dnspython
+      - py${{vars.py-version}}-ffwd
+      - py${{vars.py-version}}-gcloud-aio-storage
+      - py${{vars.py-version}}-gevent
+      - py${{vars.py-version}}-grpcio
+      - py${{vars.py-version}}-grpcio-health-checking
+      - py${{vars.py-version}}-idna
+      - py${{vars.py-version}}-parallel-ssh
+      - py${{vars.py-version}}-psutil
+      - py${{vars.py-version}}-pyopenssl
+      - py${{vars.py-version}}-requests
+      - py${{vars.py-version}}-retrying
+      - py${{vars.py-version}}-urllib3
+      - py${{vars.py-version}}-pyyaml
+
+vars:
+  py-version: 3.11
 
 environment:
   contents:
     packages:
       - build-base
-      - busybox
       - ca-certificates-bundle
-      - py3.11-installer
-      - py3.11-pip
-      - python-3.11
-      - python-3.11-dev
+      - py${{vars.py-version}}-build-base-dev
+      - py${{vars.py-version}}-poetry
       - wolfi-base
 
 pipeline:
@@ -33,46 +55,27 @@ pipeline:
       tag: v${{package.version}}
       expected-commit: 6202aca6e4c2859d2ad601571571a774df7bebc8
 
-  - name: Python Build
-    runs: |
-      pip install wheel
-      pip install poetry
-      poetry add "aiohttp==3.10.11"
-      poetry add "certifi==2024.7.4"
-      poetry add "dnspython==2.6.1"
-      poetry add "idna==3.7"
-      poetry add "pyOpenSSL@^24.0.0"
-      poetry add "cryptography@^43.0.1"
-      # CVE-2024-35195: requests
-      poetry add "requests@^2.23.0"
-      # GHSA-m5vv-6r4h-3vj9: azure-identity
-      poetry add "azure-identity==1.16.1"
-      # GHSA-34jh-p97f-mpxf: urllib3
-      poetry add "urllib3==1.26.19"
-      poetry run pip freeze | grep -v cassandra-medusa > requirements.txt
-      POETRY_VIRTUALENVS_IN_PROJECT=true poetry install
-      poetry build
-
   - runs: |
       # Setup the virtualenv
-      python -m venv .venv --system-site-packages
-      # Bump pip to patch a CVE
-      .venv/bin/pip install --upgrade pip==24.0 setuptools==70.0.0
+      python${{vars.py-version}} -m venv .venv --system-site-packages
 
-  - runs: |
-      .venv/bin/pip install -I -r requirements.txt --no-compile
-      .venv/bin/pip install -I --no-compile dist/*.whl
+  - name: Python Build
+    uses: py/pip-build-install
+    with:
+      python: .venv/bin/python${{vars.py-version}}
 
-  - runs: |
+  - name: Install deps from PyPI that aren't currently packaged in wolfi
+    runs: |
       # python-snappy is required to run medusa using $MEDUSA_MODE=GRPC.
-      .venv/bin/pip install -I python-snappy --no-compile
+      .venv/bin/pip${{vars.py-version}} install -I python-snappy --no-compile --no-deps
 
   - runs: |
       mkdir -p ${{targets.destdir}}/home/cassandra
       mv .venv ${{targets.destdir}}/home/cassandra/
 
       # edit the venv paths
-      sed -i "s|/home/build|${{targets.destdir}}/home/cassandra|g" ${{targets.destdir}}/home/cassandra/.venv/bin/*
+      find '${{targets.destdir}}/home/cassandra/.venv/bin/' -type f | \
+        xargs sed -i "s|/home/build|${{targets.destdir}}/home/cassandra|g"
 
       # allow site-packages
       sed -i "s|include-system-site-packages = false|include-system-site-packages = true|g" ${{targets.destdir}}/home/cassandra/.venv/pyvenv.cfg
@@ -95,6 +98,7 @@ subpackages:
         # The entrypoint script fails to start without bash and sleep (which comes from busybox)
         - bash
         - busybox
+        - grpc-health-probe
     pipeline:
       - runs: |
           mkdir -p "${{targets.subpkgdir}}/home/cassandra/"
@@ -113,15 +117,13 @@ test:
   environment:
     contents:
       packages:
-        - python-3.11
-        - python-3.11-dev
         - grpc-health-probe
   pipeline:
     - runs: medusa --version
     - runs: |
         set +e
         fail() { echo "$@" 1>&2; exit 1; }
-        out=$(/home/cassandra/.venv/bin/python3 -m medusa.service.grpc.server 2>&1)
+        out=$(/home/cassandra/.venv/bin/python${{vars.py-version}} -m medusa.service.grpc.server 2>&1)
         status=$?
         echo "$out" | grep -q '/etc/medusa/medusa.ini' || fail "medusa.service.grpc.server output did not contain expected 'medusa.ini' message. Exit status $status: $out"
         echo "medusa.service.grpc.server exited with expected error message"
diff --git a/py3-parallel-ssh.yaml b/py3-parallel-ssh.yaml
new file mode 100644
index 00000000000..68988ab04a0
--- /dev/null
+++ b/py3-parallel-ssh.yaml
@@ -0,0 +1,84 @@
+package:
+  name: py3-parallel-ssh
+  version: 2.12.0
+  epoch: 2
+  description: Asynchronous parallel SSH library
+  copyright:
+    - license: LGPL-2.1-or-later
+  dependencies:
+    provider-priority: 0
+
+vars:
+  pypi-package: parallel-ssh
+  import: pssh
+
+data:
+  - name: py-versions
+    items:
+      3.10: "310"
+      3.11: "311"
+
+environment:
+  contents:
+    packages:
+      - build-base
+      - busybox
+      - ca-certificates-bundle
+      - py3-supported-build-base
+      - wolfi-base
+
+pipeline:
+  - uses: fetch
+    with:
+      expected-sha256: be2c06ee8765273d204e00f82afae2dace5eebaefc5343d1dfc64513642161e0
+      uri: https://files.pythonhosted.org/packages/source/p/parallel-ssh/parallel-ssh-${{package.version}}.tar.gz
+
+  - uses: patch
+    with:
+      patches: config-parser.patch
+
+subpackages:
+  - range: py-versions
+    name: py${{range.key}}-${{vars.pypi-package}}
+    description: python${{range.key}} version of ${{vars.pypi-package}}
+    dependencies:
+      provides:
+        - py3-${{vars.pypi-package}}
+      provider-priority: ${{range.value}}
+      runtime:
+        - py${{range.key}}-gevent
+        - py${{range.key}}-ssh2-python
+        - py${{range.key}}-ssh-python
+    pipeline:
+      - uses: py/pip-build-install
+        with:
+          python: python${{range.key}}
+      - uses: strip
+    test:
+      pipeline:
+        - uses: python/import
+          with:
+            python: python${{range.key}}
+            import: ${{vars.import}}
+
+  - name: py3-supported-${{vars.pypi-package}}
+    description: meta package providing ${{vars.pypi-package}} for supported python versions.
+    dependencies:
+      runtime:
+        - py3.10-${{vars.pypi-package}}
+        - py3.11-${{vars.pypi-package}}
+    test:
+      pipeline:
+        - uses: python/import
+          with:
+            python: python3.10
+            import: ${{vars.import}}
+        - uses: python/import
+          with:
+            python: python3.11
+            import: ${{vars.import}}
+
+update:
+  enabled: true
+  release-monitor:
+    identifier: 7890
diff --git a/py3-parallel-ssh/config-parser.patch b/py3-parallel-ssh/config-parser.patch
new file mode 100644
index 00000000000..c04c7c030b0
--- /dev/null
+++ b/py3-parallel-ssh/config-parser.patch
@@ -0,0 +1,16 @@
+diff --git a/versioneer.py b/versioneer.py
+index a287060..eafcdac 100644
+--- a/versioneer.py
++++ b/versioneer.py
+@@ -339,9 +339,9 @@ def get_config_from_root(root):
+     # configparser.NoOptionError (if it lacks "VCS="). See the docstring at
+     # the top of versioneer.py for instructions on writing your setup.cfg .
+     setup_cfg = os.path.join(root, "setup.cfg")
+-    parser = configparser.SafeConfigParser()
++    parser = configparser.ConfigParser()
+     with open(setup_cfg, "r") as f:
+-        parser.readfp(f)
++        parser.read_file(f)
+     VCS = parser.get("versioneer", "VCS")  # mandatory
+ 
+     def get(parser, name):
diff --git a/py3-ssh-python.yaml b/py3-ssh-python.yaml
new file mode 100644
index 00000000000..e2224709e9f
--- /dev/null
+++ b/py3-ssh-python.yaml
@@ -0,0 +1,91 @@
+package:
+  name: py3-ssh-python
+  version: 1.0.0
+  epoch: 2
+  description: libssh C library bindings for Python.
+  copyright:
+    - license: LGPL-2.1-only
+  dependencies:
+    provider-priority: 0
+
+vars:
+  pypi-package: ssh-python
+  import: ssh
+
+data:
+  - name: py-versions
+    items:
+      3.10: "310"
+      3.11: "311"
+
+environment:
+  contents:
+    packages:
+      - build-base
+      - ca-certificates-bundle
+      - cmake
+      - libssh2
+      - libssh2-dev
+      - libssl3
+      - openssl
+      - openssl-dev
+      - py3-supported-build-base-dev
+      - zlib
+      - zlib-dev
+
+pipeline:
+  - uses: git-checkout
+    with:
+      expected-commit: a62aaf26aa18b861242364ddf3c18bc5d8343ae6
+      repository: https://github.com/ParallelSSH/ssh-python
+      tag: ${{package.version}}
+
+  - uses: patch
+    with:
+      patches: config-parser.patch
+
+subpackages:
+  - range: py-versions
+    name: py${{range.key}}-${{vars.pypi-package}}
+    description: python${{range.key}} version of ${{vars.pypi-package}}
+    dependencies:
+      provides:
+        - py3-${{vars.pypi-package}}
+      provider-priority: ${{range.value}}
+    pipeline:
+      - uses: py/pip-build-install
+        with:
+          python: python${{range.key}}
+      - uses: strip
+    test:
+      pipeline:
+        - uses: python/import
+          with:
+            python: python${{range.key}}
+            import: ${{vars.import}}
+
+  - name: py3-supported-${{vars.pypi-package}}
+    description: meta package providing ${{vars.pypi-package}} for supported python versions.
+    dependencies:
+      runtime:
+        - py3.10-${{vars.pypi-package}}
+        - py3.11-${{vars.pypi-package}}
+    test:
+      pipeline:
+        - uses: python/import
+          with:
+            python: python3.10
+            import: ${{vars.import}}
+        - uses: python/import
+          with:
+            python: python3.11
+            import: ${{vars.import}}
+        - uses: strip
+
+update:
+  enabled: true
+  ignore-regex-patterns:
+    - (.*).post(.*)
+    - 03.0
+  github:
+    identifier: ParallelSSH/ssh-python
diff --git a/py3-ssh-python/config-parser.patch b/py3-ssh-python/config-parser.patch
new file mode 100644
index 00000000000..ff392c2ce88
--- /dev/null
+++ b/py3-ssh-python/config-parser.patch
@@ -0,0 +1,16 @@
+diff --git a/versioneer.py b/versioneer.py
+index a287060..eafcdac 100644
+--- a/versioneer.py
++++ b/versioneer.py
+@@ -339,9 +339,9 @@ def get_config_from_root(root):
+     # configparser.NoOptionError (if it lacks "VCS="). See the docstring at
+     # the top of versioneer.py for instructions on writing your setup.cfg .
+     setup_cfg = os.path.join(root, "setup.cfg")
+-    parser = configparser.SafeConfigParser()
++    parser = configparser.ConfigParser()
+     with open(setup_cfg, "r") as f:
+-        parser.readfp(f)
++        parser.read_file(f)
+     VCS = parser.get("versioneer", "VCS")  # mandatory
+ 
+     def get(parser, name):
\ No newline at end of file
diff --git a/py3-ssh2-python.yaml b/py3-ssh2-python.yaml
new file mode 100644
index 00000000000..7d587cb3ab1
--- /dev/null
+++ b/py3-ssh2-python.yaml
@@ -0,0 +1,90 @@
+# Generated from https://pypi.org/project/ssh2-python/
+package:
+  name: py3-ssh2-python
+  version: 1.0.0
+  epoch: 2
+  description: Bindings for libssh2 C library
+  copyright:
+    - license: LGPL-2.1-only
+  dependencies:
+    provider-priority: 0
+
+vars:
+  pypi-package: ssh2-python
+  import: ssh2
+
+data:
+  - name: py-versions
+    items:
+      3.10: "310"
+      3.11: "311"
+
+environment:
+  contents:
+    packages:
+      - build-base
+      - ca-certificates-bundle
+      - cmake
+      - libssh2
+      - libssh2-dev
+      - libssl3
+      - openssl
+      - openssl-dev
+      - py3-supported-build-base-dev
+      - zlib
+      - zlib-dev
+
+pipeline:
+  - uses: git-checkout
+    with:
+      expected-commit: 018fd695ebadad7eed102ec3a00dcfa70cf44e83
+      repository: https://github.com/ParallelSSH/ssh2-python
+      tag: ${{package.version}}
+
+  - uses: patch
+    with:
+      patches: config-parser.patch
+
+subpackages:
+  - range: py-versions
+    name: py${{range.key}}-${{vars.pypi-package}}
+    description: python${{range.key}} version of ${{vars.pypi-package}}
+    dependencies:
+      provides:
+        - py3-${{vars.pypi-package}}
+      provider-priority: ${{range.value}}
+    pipeline:
+      - uses: py/pip-build-install
+        with:
+          python: python${{range.key}}
+      - uses: strip
+    test:
+      pipeline:
+        - uses: python/import
+          with:
+            python: python${{range.key}}
+            import: ${{vars.import}}
+
+  - name: py3-supported-${{vars.pypi-package}}
+    description: meta package providing ${{vars.pypi-package}} for supported python versions.
+    dependencies:
+      runtime:
+        - py3.10-${{vars.pypi-package}}
+        - py3.11-${{vars.pypi-package}}
+    test:
+      pipeline:
+        - uses: python/import
+          with:
+            python: python3.10
+            import: ${{vars.import}}
+        - uses: python/import
+          with:
+            python: python3.11
+            import: ${{vars.import}}
+
+update:
+  enabled: true
+  ignore-regex-patterns:
+    - (.*).post(.*)
+  github:
+    identifier: ParallelSSH/ssh2-python
diff --git a/py3-ssh2-python/config-parser.patch b/py3-ssh2-python/config-parser.patch
new file mode 100644
index 00000000000..ff392c2ce88
--- /dev/null
+++ b/py3-ssh2-python/config-parser.patch
@@ -0,0 +1,16 @@
+diff --git a/versioneer.py b/versioneer.py
+index a287060..eafcdac 100644
+--- a/versioneer.py
++++ b/versioneer.py
+@@ -339,9 +339,9 @@ def get_config_from_root(root):
+     # configparser.NoOptionError (if it lacks "VCS="). See the docstring at
+     # the top of versioneer.py for instructions on writing your setup.cfg .
+     setup_cfg = os.path.join(root, "setup.cfg")
+-    parser = configparser.SafeConfigParser()
++    parser = configparser.ConfigParser()
+     with open(setup_cfg, "r") as f:
+-        parser.readfp(f)
++        parser.read_file(f)
+     VCS = parser.get("versioneer", "VCS")  # mandatory
+ 
+     def get(parser, name):
\ No newline at end of file