diff --git a/requirements.txt b/requirements.txt
deleted file mode 100755
index 143cbf4d..00000000
--- a/requirements.txt
+++ /dev/null
@@ -1,11 +0,0 @@
-pandas>=1.5.0
-scanpy>=1.9.1
-numpy>=1.21.6
-numpy-groupies>=0.9.15
-requests>=2.25
-scikit-learn>=1.2.2
-geosketch>=1.2
-anndata>=0.8
-ktplotspy>=0.1.4
-tqdm>=4.3,<5.0
-pytest>=7.2.0
diff --git a/setup.py b/setup.py
deleted file mode 100644
index 440eb042..00000000
--- a/setup.py
+++ /dev/null
@@ -1,29 +0,0 @@
-#!/usr/bin/env python
-from setuptools import setup, find_packages
-from cellphonedb import version
-
-with open("README.md", "rt", encoding="utf-8") as fh:
-    long_description_readme_md = fh.read()
-
-with open("requirements.txt", "rt", encoding="utf-8") as fh:
-    install_requirements_txt = [line.strip() for line in fh.readlines()]
-
-setup(
-    name='CellphoneDB',
-    author='TeichLab/VentoLab',
-    author_email='contact@cellphonedb.org',
-    version=version,
-    description='Inferring cell-cell communication',
-    long_description=long_description_readme_md,
-    long_description_content_type='text/markdown',
-    packages=find_packages(),
-    include_package_data=True,
-    zip_safe=False,
-    maintainer='VentoLab',
-    maintainer_email='contact@cellphonedb.org',
-    url='https://cellphonedb.org',
-    license='MIT',
-    exclude_package_data={'': []},
-    entry_points={},
-    install_requires=install_requirements_txt,
-)