curtain-oasis.yml

unique-id: curtain-oasis
phe-label: V-21OCT-01
who-label:
alternate-names:
- AY.4.2
belongs-to-lineage:
- PANGO: AY.4.2
description: This variant is a sublineage of Delta with spike A222V and Y145H
information-sources:
- https://github.com/cov-lineages/pango-designation/issues/223
requires: empathy-serve
variants:
- amino-acid-change: A1711V
  codon-change: GCT-GTT
  gene: ORF1ab
  one-based-reference-position: 7851
  predicted-effect: non-synonymous
  protein: nsp3
  protein-codon-position: 1711
  reference-base: C
  type: SNP
  variant-base: T
- amino-acid-change: A222V
  codon-change: GCT-GTT
  gene: S
  one-based-reference-position: 22227
  predicted-effect: non-synonymous
  protein: surface glycoprotein
  protein-codon-position: 222
  reference-base: C
  type: SNP
  variant-base: T
- amino-acid-change: Y145H
  codon-change: TAC-CAC
  gene: S
  one-based-reference-position: 21995
  predicted-effect: non-synonymous
  protein: surface glycoprotein
  protein-codon-position: 145
  reference-base: T
  type: SNP
  variant-base: C
calling-definition:
  confirmed:
    mutations-required: 3
    indels-required: 0
    allowed-wildtype: 0
  probable:
    mutations-required: 2
    indels-required: 0
    allowed-wildtype: 0
  low-qc:
    mutations-required: 0
    indels-required: 0
    allowed-wildtype: 0
acknowledgements:
curators:
- Natalie Groves
- Manon Ragonnet