diff --git a/src/Collections/CollectionRepository.php b/src/Collections/CollectionRepository.php
index 136ca2e0..f87a58fc 100644
--- a/src/Collections/CollectionRepository.php
+++ b/src/Collections/CollectionRepository.php
@@ -4,6 +4,7 @@
 
 use Illuminate\Support\Collection as IlluminateCollection;
 use Statamic\Contracts\Entries\Collection as CollectionContract;
+use Statamic\Eloquent\Jobs\UpdateCollectionEntryUris;
 use Statamic\Facades\Blink;
 use Statamic\Stache\Repositories\CollectionRepository as StacheRepository;
 
@@ -33,8 +34,25 @@ public function findByHandle($handle): ?CollectionContract
     public function save($entry)
     {
         $model = $entry->toModel();
+        $original = $model->getOriginal();
+
         $model->save();
 
+        if (
+            $model->wasChanged('settings')
+            && ($model->settings['routes'] ?? null) !== ($original['settings']['routes'] ?? null)
+        ) {
+            $dispatch = UpdateCollectionEntryUris::dispatch($entry->handle());
+
+            $connection = config('statamic.eloquent-driver.collections.update_entry_uris_connection', 'default');
+
+            if ($connection != 'default') {
+                $dispatch->onConnection($connection);
+            }
+
+            $dispatch->onQueue(config('statamic.eloquent-driver.collections.update_entry_uris_queue', 'default'));
+        }
+
         Blink::forget("eloquent-collection-{$model->handle}");
         Blink::forget('eloquent-collections');
 
diff --git a/src/Jobs/UpdateCollectionEntryUris.php b/src/Jobs/UpdateCollectionEntryUris.php
new file mode 100644
index 00000000..9245d759
--- /dev/null
+++ b/src/Jobs/UpdateCollectionEntryUris.php
@@ -0,0 +1,23 @@
+<?php
+
+namespace Statamic\Eloquent\Jobs;
+
+use Illuminate\Bus\Queueable;
+use Illuminate\Contracts\Queue\ShouldQueue;
+use Illuminate\Foundation\Bus\Dispatchable;
+use Illuminate\Queue\InteractsWithQueue;
+use Statamic\Facades\Entry;
+
+class UpdateCollectionEntryUris implements ShouldQueue
+{
+    use Dispatchable, InteractsWithQueue, Queueable;
+
+    public function __construct(public string $collection) {}
+
+    public function handle()
+    {
+        Entry::query()
+            ->where('collection', $this->collection)
+            ->chunk(100, fn ($entries) => $entries->each->save());
+    }
+}
diff --git a/tests/Entries/CollectionTest.php b/tests/Entries/CollectionTest.php
new file mode 100644
index 00000000..7040e1f7
--- /dev/null
+++ b/tests/Entries/CollectionTest.php
@@ -0,0 +1,68 @@
+<?php
+
+namespace Entries;
+
+use Illuminate\Foundation\Testing\RefreshDatabase;
+use Illuminate\Support\Facades\Queue;
+use PHPUnit\Framework\Attributes\Test;
+use Statamic\Eloquent\Collections\Collection;
+use Statamic\Eloquent\Collections\CollectionModel;
+use Statamic\Eloquent\Jobs\UpdateCollectionEntryUris;
+use Statamic\Facades\Collection as CollectionFacade;
+use Statamic\Facades\Entry as EntryFacade;
+use Tests\TestCase;
+
+class CollectionTest extends TestCase
+{
+    use RefreshDatabase;
+
+    #[Test]
+    public function it_finds_collection()
+    {
+        $model = CollectionModel::create([
+            'title' => 'Blog',
+            'handle' => 'blog',
+            'settings' => [],
+        ]);
+
+        $find = CollectionFacade::find('blog');
+
+        $this->assertTrue($model->is($find->model()));
+        $this->assertEquals('blog', $find->handle());
+        $this->assertEquals('Blog', $find->title());
+    }
+
+    #[Test]
+    public function it_saves_to_collection_model()
+    {
+        $collection = (new Collection)->handle('test');
+
+        $this->assertDatabaseMissing('collections', ['handle' => 'test']);
+
+        $collection->save();
+
+        $this->assertDatabaseHas('collections', ['handle' => 'test']);
+    }
+
+    #[Test]
+    public function changing_a_collections_route_updates_entry_uris()
+    {
+        Queue::fake();
+
+        $collection = (new Collection)->handle('test');
+        $collection->save();
+
+        EntryFacade::make()->collection('test')->slug('one');
+        EntryFacade::make()->collection('test')->slug('two');
+        EntryFacade::make()->collection('test')->slug('three');
+
+        $collection->routes(['en' => '/blog/{slug}'])->save();
+        $collection->routes(['en' => '/{slug}'])->save();
+        $collection->routes(['en' => '/{slug}'])->save();
+        $collection->routes(['en' => null])->save();
+
+        // The job should only be dispatched three times.
+        // It shouldn't be dispatched when the route is null or hasn't changed since the last save.
+        Queue::assertPushed(UpdateCollectionEntryUris::class, 3);
+    }
+}