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Addition Description
It would be nice to have way to perform a centered-log ratio transform within QIIME 2 for downstream analyses, visualizations, and just having around in general.
Current Behavior
There's an rclr-transformation function in gemelli which is slightly different due to the way it handles zeros.
Proposed Behavior
It would be nice to have a function with a classic CLR with either a pseudocount or low zero substitution option. I'm not sure what people would do with it downstream, but it would be nice to have, since we already have ILR in gneiss and ALR in qurro.
Addition Description
It would be nice to have way to perform a centered-log ratio transform within QIIME 2 for downstream analyses, visualizations, and just having around in general.
Current Behavior
There's an
rclr-transformation
function ingemelli
which is slightly different due to the way it handles zeros.Proposed Behavior
It would be nice to have a function with a classic CLR with either a pseudocount or low zero substitution option. I'm not sure what people would do with it downstream, but it would be nice to have, since we already have ILR in gneiss and ALR in qurro.
References
This is partially inspired by https://forum.qiime2.org/t/obtain-normalized-data-ancom/22021
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