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Implementing Patlak model #50

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angmnlc opened this issue Jun 14, 2023 · 0 comments
Open

Implementing Patlak model #50

angmnlc opened this issue Jun 14, 2023 · 0 comments

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@angmnlc
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angmnlc commented Jun 14, 2023

Hi there,

Our team would be interested in using Quantiphyse for our new project involving T1-DCE. Our clinical collaborators recommended we use the Patlak model [1,2] instead of those already available in Quantiphyse.

We were wondering if it would be feasible to have the Patlak model available in Quantiphyse. Thank you.

References:
[1] Patlak CS, Blasberg RG, Fenstermacher JD. Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data. Journal of Cerebral Blood Flow & Metabolism. 1983;3(1):1-7. doi:10.1038/jcbfm.1983.1
[2] Larsson HB, Courivaud F, Rostrup E, Hansen AE. Measurement of brain perfusion, blood volume, and blood-brain barrier permeability, using dynamic contrast-enhanced T(1)-weighted MRI at 3 tesla. Magn Reson Med. 2009 Nov;62(5):1270-81. doi: 10.1002/mrm.22136. PMID: 19780145.

Kind regards! @angmnlc @srikash

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