diff --git a/specfile/sourcelist.py b/specfile/sourcelist.py
index da70bec..97b8113 100644
--- a/specfile/sourcelist.py
+++ b/specfile/sourcelist.py
@@ -5,7 +5,9 @@
 import copy
 from typing import TYPE_CHECKING, Any, Dict, List, Optional, overload
 
+from specfile.conditions import process_conditions
 from specfile.formatter import formatted
+from specfile.macro_definitions import MacroDefinitions
 from specfile.macros import Macros
 from specfile.sections import Section
 from specfile.tags import Comments
@@ -22,10 +24,15 @@ class SourcelistEntry:
     Attributes:
         location: Literal location of the source/patch as stored in the spec file.
         comments: List of comments associated with the source/patch.
+        valid: Whether the entry is not located in a false branch of a condition.
     """
 
     def __init__(
-        self, location: str, comments: Comments, context: Optional["Specfile"] = None
+        self,
+        location: str,
+        comments: Comments,
+        valid: bool = True,
+        context: Optional["Specfile"] = None,
     ) -> None:
         """
         Constructs a `SourceListEntry` object.
@@ -33,6 +40,7 @@ def __init__(
         Args:
             location: Literal location of the source/patch as stored in the spec file.
             comments: List of comments associated with the source/patch.
+            valid: Whether the entry is not located in a false branch of a condition.
             context: `Specfile` instance that defines the context for macro expansions.
 
         Returns:
@@ -40,6 +48,7 @@ def __init__(
         """
         self.location = location
         self.comments = comments.copy()
+        self.valid = valid
         self._context = context
 
     def __eq__(self, other: object) -> bool:
@@ -50,7 +59,8 @@ def __eq__(self, other: object) -> bool:
     @formatted
     def __repr__(self) -> str:
         return (
-            f"SourcelistEntry({self.location!r}, {self.comments!r}, {self._context!r})"
+            f"SourcelistEntry({self.location!r}, {self.comments!r}, "
+            f"{self.valid!r}, {self._context!r})"
         )
 
     def __deepcopy__(self, memo: Dict[int, Any]) -> "SourcelistEntry":
@@ -134,11 +144,15 @@ def parse(
         Returns:
             Constructed instance of `Sourcelist` class.
         """
+        macro_definitions = MacroDefinitions.parse(list(section))
+        lines = process_conditions(list(section), macro_definitions, context)
         data = []
         buffer: List[str] = []
-        for line in section:
+        for line, valid in lines:
             if line and not line.lstrip().startswith("#"):
-                data.append(SourcelistEntry(line, Comments.parse(buffer), context))
+                data.append(
+                    SourcelistEntry(line, Comments.parse(buffer), valid, context)
+                )
                 buffer = []
             else:
                 buffer.append(line)
diff --git a/specfile/sources.py b/specfile/sources.py
index 62986c2..34b6675 100644
--- a/specfile/sources.py
+++ b/specfile/sources.py
@@ -66,6 +66,12 @@ def comments(self) -> Comments:
         """List of comments associated with the source."""
         ...
 
+    @property
+    @abstractmethod
+    def valid(self) -> bool:
+        """Whether the source is not located in a false branch of a condition."""
+        ...
+
 
 class TagSource(Source):
     """Class that represents a source backed by a spec file tag."""
@@ -161,6 +167,11 @@ def comments(self) -> Comments:
         """List of comments associated with the source."""
         return self._tag.comments
 
+    @property
+    def valid(self) -> bool:
+        """Whether the source is not located in a false branch of a condition."""
+        return self._tag.valid
+
 
 class ListSource(Source):
     """Class that represents a source backed by a line in a %sourcelist section."""
@@ -224,6 +235,11 @@ def comments(self) -> Comments:
         """List of comments associated with the source."""
         return self._source.comments
 
+    @property
+    def valid(self) -> bool:
+        """Whether the source is not located in a false branch of a condition."""
+        return self._source.valid
+
 
 class Sources(collections.abc.MutableSequence):
     """Class that represents a sequence of all sources."""
@@ -537,12 +553,15 @@ def insert(self, i: int, location: str) -> None:
                 container.insert(
                     index,
                     SourcelistEntry(  # type: ignore[arg-type]
-                        location, Comments(), context=self._context
+                        location,
+                        Comments(),
+                        container[index - 1].valid,
+                        context=self._context,
                     ),
                 )
         elif self._sourcelists:
             self._sourcelists[-1].append(
-                SourcelistEntry(location, Comments(), context=self._context)
+                SourcelistEntry(location, Comments(), True, context=self._context)
             )
         else:
             index, name, separator = self._get_initial_tag_setup()