diff --git a/nexus/db-queries/src/db/datastore/mod.rs b/nexus/db-queries/src/db/datastore/mod.rs
index f9e0be81c1..bc20d7a6cc 100644
--- a/nexus/db-queries/src/db/datastore/mod.rs
+++ b/nexus/db-queries/src/db/datastore/mod.rs
@@ -877,10 +877,21 @@ mod test {
             assert_eq!(expected_region_count, dataset_and_regions.len());
             let mut disk_datasets = HashSet::new();
             let mut disk_zpools = HashSet::new();
+            let mut regions = HashSet::new();
 
             for (dataset, region) in dataset_and_regions {
                 // Must be 3 unique datasets
                 assert!(disk_datasets.insert(dataset.id()));
+                // All regions should be unique
+                assert!(regions.insert(region.id()));
+
+                // Check there's no cross contamination between returned UUIDs
+                //
+                // This is a little goofy, but it catches a bug that has
+                // happened before. The returned columns share names (like
+                // "id"), so we need to process them in-order.
+                assert!(regions.get(&dataset.id()).is_none());
+                assert!(disk_datasets.get(&region.id()).is_none());
 
                 // Dataset must not be non-provisionable.
                 assert_ne!(dataset.id(), non_provisionable_dataset_id);