diff --git a/tests/drivers/mspi/api/boards/nrf54l15dk_nrf54l15_cpuapp.overlay b/tests/drivers/mspi/api/boards/nrf54l15dk_nrf54l15_cpuapp.overlay
new file mode 100644
index 00000000000..0bc92a235bc
--- /dev/null
+++ b/tests/drivers/mspi/api/boards/nrf54l15dk_nrf54l15_cpuapp.overlay
@@ -0,0 +1,24 @@
+/*
+ * Copyright (c) 2024 Nordic Semiconductor ASA
+ *
+ * SPDX-License-Identifier: Apache-2.0
+ */
+
+ / {
+	aliases {
+		mspi0 = &sdp_mspi;
+	};
+};
+
+&cpuflpr_vpr {
+	status = "okay";
+
+	sdp_mspi: sdp_mspi@5004c000 {
+		mspi_device: mspi_device@0 {
+			status = "okay";
+			compatible = "zephyr,mspi-emul-device";
+			reg = <0x0>;
+			mspi-max-frequency = <48000000>;
+		};
+	};
+};
\ No newline at end of file
diff --git a/tests/drivers/mspi/api/src/main.c b/tests/drivers/mspi/api/src/main.c
index d6b632f29c1..7d5daa7bbbe 100644
--- a/tests/drivers/mspi/api/src/main.c
+++ b/tests/drivers/mspi/api/src/main.c
@@ -20,7 +20,11 @@ typedef struct mspi_ambiq_timing_cfg mspi_timing_cfg;
 typedef enum mspi_ambiq_timing_param mspi_timing_param;
 #endif
 
+// #if defined(CONFIG_SOC_NRF54L15_CPUAPP)
+// #define MSPI_BUS_NODE       DT_NODELABEL(sdp_mspi)
+// #else
 #define MSPI_BUS_NODE       DT_ALIAS(mspi0)
+// #endif
 
 static const struct device *mspi_devices[] = {
 	DT_FOREACH_CHILD_STATUS_OKAY_SEP(MSPI_BUS_NODE, DEVICE_DT_GET, (,))
@@ -51,13 +55,17 @@ static struct mspi_dev_cfg device_cfg[] = {
 	DT_FOREACH_CHILD_STATUS_OKAY_SEP(MSPI_BUS_NODE, MSPI_DEVICE_CONFIG_DT, (,))
 };
 
+#if CONFIG_MSPI_XIP
 static struct mspi_xip_cfg xip_cfg[] = {
 	DT_FOREACH_CHILD_STATUS_OKAY_SEP(MSPI_BUS_NODE, MSPI_XIP_CONFIG_DT, (,))
 };
+#endif
 
+#if CONFIG_MSPI_SCRAMBLE
 static struct mspi_scramble_cfg scramble_cfg[] = {
 	DT_FOREACH_CHILD_STATUS_OKAY_SEP(MSPI_BUS_NODE, MSPI_SCRAMBLE_CONFIG_DT, (,))
 };
+#endif
 
 ZTEST(mspi_api, test_mspi_api)
 {
@@ -102,9 +110,11 @@ ZTEST(mspi_api, test_mspi_api)
 		zassert_equal(ret, 0, "mspi_timing_config failed.");
 #endif
 
+#if CONFIG_MSPI_ASYNC
 		ret = mspi_register_callback(mspi_bus, &dev_id[dev_idx],
 					     MSPI_BUS_XFER_COMPLETE, NULL, NULL);
 		zassert_equal(ret, 0, "mspi_register_callback failed.");
+#endif
 
 		ret = mspi_get_channel_status(mspi_bus, 0);
 		zassert_equal(ret, 0, "mspi_get_channel_status failed.");
diff --git a/tests/drivers/mspi/api/testcase.yaml b/tests/drivers/mspi/api/testcase.yaml
index 3675cc485f3..730f6f61438 100644
--- a/tests/drivers/mspi/api/testcase.yaml
+++ b/tests/drivers/mspi/api/testcase.yaml
@@ -15,3 +15,19 @@ tests:
       - apollo3p_evb
     integration_platforms:
       - native_sim
+
+  drivers.mspi.api.emspi:
+    tags:
+      - drivers
+      - mspi
+      - api
+    harness: ztest
+    platform_allow:
+      - nrf54l15dk_nrf54l15_cpuapp
+    integration_platforms:
+      - nrf54l15dk_nrf54l15_cpuapp
+    extra_args:
+      - SB_CONFIG_VPR_LAUNCHER=n
+      - SB_CONFIG_PARTITION_MANAGER=n
+      - SB_CONFIG_SDP=y
+      - SB_CONFIG_SDP_MSPI=y