diff --git a/CHANGELOG.md b/CHANGELOG.md
index 5045622b4..e67dce371 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -15,6 +15,7 @@
 ### General
 
 - Fix `process.shell` in `nextflow.config` ([#3416](https://github.com/nf-core/tools/pull/3416))
+- Update python:3.12-slim Docker digest to 123be56 ([#3421](https://github.com/nf-core/tools/pull/3421))
 
 ## [v3.1.2 - Brass Boxfish Patch](https://github.com/nf-core/tools/releases/tag/3.1.2) - [2025-01-20]
 
diff --git a/Dockerfile b/Dockerfile
index f5a6796a2..d26381a06 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -1,4 +1,4 @@
-FROM python:3.12-slim@sha256:10f3aaab98db50cba827d3b33a91f39dc9ec2d02ca9b85cbc5008220d07b17f3
+FROM python:3.12-slim@sha256:123be5684f39d8476e64f47a5fddf38f5e9d839baff5c023c815ae5bdfae0df7
 LABEL authors="phil.ewels@seqera.io,erik.danielsson@scilifelab.se" \
     description="Docker image containing requirements for nf-core/tools"