DESCRIPTION

Package: adestr
Type: Package
Title: Estimation in Optimal Adaptive Two-Stage Designs
Version: 1.0.0
Authors@R:c(person("Jan", "Meis", role = c("aut", "cre"), email = "meis@imbi.uni-heidelberg.de", comment = c(ORCID = "0000-0001-5407-7220")),
  person("Martin", "Maechler", role = c("cph"), email = "maechler@stat.math.ethz.ch", comment = c(ORCID = "0000-0002-8685-9910", "Original author of monoSpl.c (from the 'stats' package).")))
Description:
  Methods to evaluate the performance characteristics of
  various point and interval estimators for optimal adaptive two-stage designs as described
  in Meis et al. (2024) <doi:10.1002/sim.10020>.
  Specifically, this package is written to work with trial designs created by the 'adoptr' package
  (Kunzmann et al. (2021) <doi:10.18637/jss.v098.i09>; Pilz et al. (2021) <doi:10.1002/sim.8953>)).
  Apart from the a priori evaluation of performance characteristics, this package also allows for the
  evaluation of the implemented estimators on real datasets, and it implements methods
  to calculate p-values.
License: GPL (>= 2)
Copyright:
  This package contains a modified version of the monotonic spline functions from the
  'stats' package. Specifically, the code is containted in the files 'R/fastmonoHFC.R',
  'src/fastmonoHFC.c', 'src/modreg.h' and 'src/monoSpl.c'. The R Core team and Martin Maechler 
  are the copyright holders of the original code.
  Jan Meis is the copyright holder of everything else.
Encoding: UTF-8
LazyData: true
VignetteBuilder: knitr
RoxygenNote: 7.2.3
Depends:
    R (>= 4.0.0),
    adoptr
Imports: 
    methods,
    stats,
    grDevices,
    cubature,
    ggplot2,
    ggpubr,
    scales,
    latex2exp,
    forcats,
    future.apply,
    progressr,
    Rdpack
Suggests: 
    covr,
    knitr,
    rmarkdown,
    testthat (>= 3.0.0), 
    microbenchmark
Config/testthat/edition: 3
Collate: 
    'adestr_package.R'
    'twostagedesign_with_cache.R'
    'analyze.R'
    'estimators.R'
    'densities.R'
    'evaluate_estimator.R'
    'fastmonoHFC.R'
    'fisher_information.R'
    'hcubature.R'
    'helper_functions.R'
    'integrate_over_sample_space.R'
    'reference_implementation.R'
    'mle_distribution.R'
    'mlmse_score.R'
    'n2c2_helpers.R'
    'plot.R'
    'priors.R'
    'print.R'
URL: https://jan-imbi.github.io/adestr/
RdMacros: Rdpack