[1] "2024-11-30 17:35:22 UTC"
+[1] "2024-12-04 17:38:02 UTC"
[1] "2024-11-30 17:35:22 UTC"
+[1] "2024-12-04 17:38:02 UTC"
[1] "2024-11-30 17:36:26 UTC"
+[1] "2024-12-04 17:39:02 UTC"
[1] "2024-11-30 17:35:59 UTC"
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[1] "2024-11-30 17:34:58 UTC"
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[1] "2024-11-30 17:37:03 UTC"
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[1] "2024-11-30 17:37:56 UTC"
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[1] "2024-11-30 17:37:22 UTC"
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[1] "2024-11-30 17:37:43 UTC"
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[1] "2024-11-30 17:38:58 UTC"
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[1] "2024-11-30 17:39:59 UTC"
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[1] "2024-11-30 17:39:45 UTC"
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[1] "2024-11-30 17:39:52 UTC"
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[1] "2024-11-30 17:39:38 UTC"
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[1] "2024-11-30 17:39:31 UTC"
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[1] "2024-11-30 17:39:07 UTC"
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[1] "2024-11-30 17:39:15 UTC"
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[1] "2024-11-30 18:10:07 UTC"
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[1] "2024-11-30 18:10:12 UTC"
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[1] "2024-11-30 18:09:10 UTC"
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[1] "2024-11-30 18:09:06 UTC"
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[1] "2024-11-30 18:09:15 UTC"
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[1] "2024-11-30 18:09:01 UTC"
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[1] "2024-12-02 15:44:55 UTC"
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[1] "2024-11-30 18:08:56 UTC"
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[1] "2024-11-30 18:08:52 UTC"
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[1] "2024-11-30 18:08:43 UTC"
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[1] "2024-11-30 18:08:47 UTC"
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[1] "2024-11-30 18:08:38 UTC"
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[1] "2024-11-30 18:09:29 UTC"
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[1] "2024-11-30 18:09:33 UTC"
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[1] "2024-11-30 18:07:59 UTC"
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[1] "2024-11-30 18:09:24 UTC"
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[1] "2024-11-30 18:08:14 UTC"
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[1] "2024-11-30 18:08:19 UTC"
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[1] "2024-11-30 18:08:29 UTC"
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[1] "2024-11-30 18:08:24 UTC"
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[1] "2024-11-30 18:08:09 UTC"
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[1] "2024-11-30 18:08:34 UTC"
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[1] "2024-11-30 18:09:48 UTC"
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[1] "2024-11-30 18:09:58 UTC"
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[1] "2024-11-30 18:09:38 UTC"
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[1] "2024-11-30 18:09:43 UTC"
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[1] "2024-11-30 18:09:53 UTC"
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[1] "2024-11-30 18:10:02 UTC"
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[1] "2024-11-30 18:08:04 UTC"
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[1] "2024-11-30 18:07:55 UTC"
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[1] "2024-11-30 18:06:06 UTC"
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[1] "2024-11-30 18:05:45 UTC"
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[1] "2024-11-30 18:06:13 UTC"
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[1] "2024-11-30 18:05:52 UTC"
+[1] "2024-12-04 18:07:45 UTC"
[1] "2024-11-30 18:05:59 UTC"
+[1] "2024-12-04 18:07:52 UTC"
[1] "2024-11-30 18:07:15 UTC"
+[1] "2024-12-04 18:09:07 UTC"
[1] "2024-11-30 18:06:29 UTC"
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[1] "2024-11-30 18:06:53 UTC"
+[1] "2024-12-04 18:08:45 UTC"
[1] "2024-11-30 18:07:49 UTC"
+[1] "2024-12-04 18:09:39 UTC"
[1] "2024-11-30 18:07:37 UTC"
+[1] "2024-12-04 18:09:28 UTC"
[1] "2024-11-30 18:01:40 UTC"
+[1] "2024-12-04 18:03:38 UTC"
[1] "2024-11-30 17:59:30 UTC"
+[1] "2024-12-04 18:01:31 UTC"
[1] "2024-11-30 18:02:09 UTC"
+[1] "2024-12-04 18:04:07 UTC"
[1] "2024-11-30 17:57:36 UTC"
+[1] "2024-12-04 17:59:41 UTC"
[1] "2024-11-30 18:02:32 UTC"
+[1] "2024-12-04 18:04:29 UTC"
[1] "2024-11-30 18:00:05 UTC"
+[1] "2024-12-04 18:02:04 UTC"
[1] "2024-11-30 18:00:33 UTC"
+[1] "2024-12-04 18:02:33 UTC"
[1] "2024-11-30 17:58:25 UTC"
+[1] "2024-12-04 18:00:29 UTC"
[1] "2024-11-30 17:59:06 UTC"
+[1] "2024-12-04 18:01:08 UTC"
[1] "2024-11-30 17:58:04 UTC"
+[1] "2024-12-04 18:00:08 UTC"
[1] "2024-11-30 18:00:56 UTC"
+[1] "2024-12-04 18:02:55 UTC"
[1] "2024-11-30 17:58:46 UTC"
+[1] "2024-12-04 18:00:49 UTC"
[1] "2024-11-30 18:01:18 UTC"
+[1] "2024-12-04 18:03:17 UTC"
[1] "2024-11-30 18:02:53 UTC"
+[1] "2024-12-04 18:04:50 UTC"
[1] "2024-11-30 18:03:13 UTC"
+[1] "2024-12-04 18:05:10 UTC"
[1] "2024-11-30 17:56:07 UTC"
+[1] "2024-12-04 17:58:14 UTC"
[1] "2024-11-30 17:56:31 UTC"
+[1] "2024-12-04 17:58:37 UTC"
[1] "2024-11-30 17:56:55 UTC"
+[1] "2024-12-04 17:59:00 UTC"
[1] "2024-11-30 17:57:16 UTC"
+[1] "2024-12-04 17:59:21 UTC"
[1] "2024-11-30 17:54:51 UTC"
+[1] "2024-12-04 17:57:00 UTC"
[1] "2024-11-30 17:48:07 UTC"
+[1] "2024-12-04 17:50:31 UTC"
[1] "2024-11-30 17:47:48 UTC"
+[1] "2024-12-04 17:50:13 UTC"
[1] "2024-11-30 17:47:32 UTC"
+[1] "2024-12-04 17:49:58 UTC"
[1] "2024-11-30 17:47:39 UTC"
+[1] "2024-12-04 17:50:04 UTC"
[1] "2024-11-30 18:04:03 UTC"
+[1] "2024-12-04 18:05:58 UTC"
[1] "2024-11-30 18:04:24 UTC"
+[1] "2024-12-04 18:06:18 UTC"
[1] "2024-11-30 18:03:47 UTC"
+[1] "2024-12-04 18:05:42 UTC"
[1] "2024-11-30 17:46:36 UTC"
+[1] "2024-12-04 17:49:03 UTC"
[1] "2024-11-30 17:46:14 UTC"
+[1] "2024-12-04 17:48:41 UTC"
[1] "2024-11-30 17:42:18 UTC"
+[1] "2024-12-04 17:44:49 UTC"
[1] "2024-11-30 17:42:05 UTC"
+[1] "2024-12-04 17:44:37 UTC"
[1] "2024-11-30 17:40:58 UTC"
+[1] "2024-12-04 17:43:31 UTC"
[1] "2024-11-30 17:41:20 UTC"
+[1] "2024-12-04 17:43:53 UTC"
[1] "2024-11-30 17:42:35 UTC"
+[1] "2024-12-04 17:45:05 UTC"
[1] "2024-11-30 17:41:44 UTC"
+[1] "2024-12-04 17:44:16 UTC"
[1] "2024-11-30 17:45:52 UTC"
+[1] "2024-12-04 17:48:19 UTC"
[1] "2024-11-30 17:45:08 UTC"
+[1] "2024-12-04 17:47:37 UTC"
[1] "2024-11-30 17:45:28 UTC"
+[1] "2024-12-04 17:47:57 UTC"
B: Placebo A: Drug X C: Combination
- (N=134) (N=134) (N=132)
-———————————————————————————————————————————————————————————————————————————————————————————————————
-Number of exacerbations per patient
- 0 10 (7.46%) 6 (4.48%) 11 (8.33%)
- 1 25 (18.66%) 21 (15.67%) 14 (10.61%)
- 2 38 (28.36%) 41 (30.60%) 33 (25.00%)
- 3 22 (16.42%) 26 (19.40%) 21 (15.91%)
- 4 13 (9.70%) 18 (13.43%) 30 (22.73%)
- 5 11 (8.21%) 10 (7.46%) 12 (9.09%)
- 6 10 (7.46%) 7 (5.22%) 7 (5.30%)
- 7 3 (2.24%) 4 (2.99%) 3 (2.27%)
- 8 1 (0.75%) 1 (0.75%) 1 (0.76%)
- 9 1 (0.75%) 0 (0.00%) 0 (0.00%)
-Unadjusted exacerbation rate (per year)
- Rate 7.2364 8.2148 9.8131
-Adjusted (QP) exacerbation rate (per year)
- Rate 2.4550 2.8514 3.4304
- Rate CI (1.6194, 3.7219) (1.8974, 4.2850) (2.2946, 5.1284)
- Rate Ratio 1.1615 1.3973
- Rate Ratio CI (0.6462, 2.0877) (0.7789, 2.5067)
- p-value 0.6169 0.2619
-Adjusted (NB) exacerbation rate (per year)
- Rate 2.7374 2.8150 2.9789
- Rate CI (2.3932, 3.1311) (2.4681, 3.2106) (2.6152, 3.3932)
- Rate Ratio 1.0283 1.0882
- Rate Ratio CI (0.8856, 1.1941) (0.9381, 1.2624)
- p-value 0.7140 0.2643
+ B: Placebo A: Drug X C: Combination
+ (N=134) (N=134) (N=132)
+—————————————————————————————————————————————————————————————————————————————————————————————————————————
+Number of exacerbations per patient
+ 0 10 (7.46%) 6 (4.48%) 11 (8.33%)
+ 1 25 (18.66%) 21 (15.67%) 14 (10.61%)
+ 2 38 (28.36%) 41 (30.60%) 33 (25.00%)
+ 3 22 (16.42%) 26 (19.40%) 21 (15.91%)
+ 4 13 (9.70%) 18 (13.43%) 30 (22.73%)
+ 5 11 (8.21%) 10 (7.46%) 12 (9.09%)
+ 6 10 (7.46%) 7 (5.22%) 7 (5.30%)
+ 7 3 (2.24%) 4 (2.99%) 3 (2.27%)
+ 8 1 (0.75%) 1 (0.75%) 1 (0.76%)
+ 9 1 (0.75%) 0 (0.00%) 0 (0.00%)
+Unadjusted exacerbation rate (per year)
+ Rate 7.2364 8.2148 9.8131
+Adjusted (QP) exacerbation rate (per year)
+ Rate 2.4550 2.8514 3.4304
+ Rate CI (1.6194, 3.7219) (1.8974, 4.2850) (2.2946, 5.1284)
+ Rate Ratio 1.1615 1.3973
+ Rate Ratio CI (0.6462, 2.0877) (0.7789, 2.5067)
+ p-value 0.6169 0.2619
+Adjusted (NB) exacerbation rate (per year)
+ Rate 18.4450 28.0582 23.9304
+ Rate CI (13.9015, 24.4736) (21.3288, 36.9108) (18.1382, 31.5722)
+ Rate Ratio 1.5212 1.2974
+ Rate Ratio CI (1.1166, 2.0724) (0.9505, 1.7708)
+ p-value 0.0078 0.1009
[1] "2024-11-30 17:42:48 UTC"
+[1] "2024-12-04 17:45:18 UTC"
SAMPLING FOR MODEL 'rbmi_mmrm' NOW (CHAIN 1).
Chain 1:
-Chain 1: Gradient evaluation took 0.000239 seconds
-Chain 1: 1000 transitions using 10 leapfrog steps per transition would take 2.39 seconds.
+Chain 1: Gradient evaluation took 0.000218 seconds
+Chain 1: 1000 transitions using 10 leapfrog steps per transition would take 2.18 seconds.
Chain 1: Adjust your expectations accordingly!
Chain 1:
Chain 1:
@@ -1537,9 +1537,9 @@
Chain 1: Iteration: 1160 / 1200 [ 96%] (Sampling)
Chain 1: Iteration: 1200 / 1200 [100%] (Sampling)
Chain 1:
-Chain 1: Elapsed Time: 0.502 seconds (Warm-up)
-Chain 1: 1.639 seconds (Sampling)
-Chain 1: 2.141 seconds (Total)
+Chain 1: Elapsed Time: 0.52 seconds (Warm-up)
+Chain 1: 1.631 seconds (Sampling)
+Chain 1: 2.151 seconds (Total)
Chain 1:
[1] "2024-11-30 17:44:16 UTC"
+[1] "2024-12-04 17:46:47 UTC"
[1] "2024-11-30 17:40:32 UTC"
+[1] "2024-12-04 17:43:06 UTC"
[1] "2024-11-30 17:44:38 UTC"
+[1] "2024-12-04 17:47:08 UTC"
[1] "2024-11-30 18:03:36 UTC"
+[1] "2024-12-04 18:05:31 UTC"
[1] "2024-11-30 17:50:18 UTC"
+[1] "2024-12-04 17:52:38 UTC"
[1] "2024-11-30 17:52:55 UTC"
+[1] "2024-12-04 17:55:07 UTC"
[1] "2024-11-30 17:51:22 UTC"
+[1] "2024-12-04 17:53:37 UTC"
[1] "2024-11-30 17:52:27 UTC"
+[1] "2024-12-04 17:54:40 UTC"
[1] "2024-11-30 17:51:04 UTC"
+[1] "2024-12-04 17:53:20 UTC"
[1] "2024-11-30 17:50:33 UTC"
+[1] "2024-12-04 17:52:51 UTC"
[1] "2024-11-30 17:51:43 UTC"
+[1] "2024-12-04 17:53:58 UTC"
[1] "2024-11-30 17:52:39 UTC"
+[1] "2024-12-04 17:54:51 UTC"
[1] "2024-11-30 17:49:54 UTC"
+[1] "2024-12-04 17:52:15 UTC"
[1] "2024-11-30 17:54:07 UTC"
+[1] "2024-12-04 17:56:18 UTC"
[1] "2024-11-30 17:54:15 UTC"
+[1] "2024-12-04 17:56:24 UTC"
[1] "2024-11-30 17:53:55 UTC"
+[1] "2024-12-04 17:56:06 UTC"
[1] "2024-11-30 17:52:06 UTC"
+[1] "2024-12-04 17:54:20 UTC"
[1] "2024-11-30 17:53:39 UTC"
+[1] "2024-12-04 17:55:49 UTC"
[1] "2024-11-30 17:50:01 UTC"
+[1] "2024-12-04 17:52:22 UTC"
[1] "2024-11-30 17:53:26 UTC"
+[1] "2024-12-04 17:55:37 UTC"
[1] "2024-11-30 17:54:38 UTC"
+[1] "2024-12-04 17:56:48 UTC"
[1] "2024-11-30 17:50:50 UTC"
+[1] "2024-12-04 17:53:08 UTC"
[1] "2024-11-30 17:55:09 UTC"
+[1] "2024-12-04 17:57:17 UTC"
[1] "2024-11-30 18:05:19 UTC"
+[1] "2024-12-04 18:07:12 UTC"
[1] "2024-11-30 18:05:39 UTC"
+[1] "2024-12-04 18:07:31 UTC"
[1] "2024-11-30 18:05:32 UTC"
+[1] "2024-12-04 18:07:25 UTC"
[1] "2024-11-30 18:05:10 UTC"
+[1] "2024-12-04 18:07:03 UTC"
[1] "2024-11-30 18:04:43 UTC"
+[1] "2024-12-04 18:06:36 UTC"
[1] "2024-11-30 18:04:56 UTC"
+[1] "2024-12-04 18:06:49 UTC"
[1] "2024-11-30 18:05:03 UTC"
+[1] "2024-12-04 18:06:56 UTC"
[1] "2024-11-30 18:04:35 UTC"
+[1] "2024-12-04 18:06:29 UTC"
[1] "2024-11-30 18:04:50 UTC"
+[1] "2024-12-04 18:06:43 UTC"