diff --git a/RNA-seq/renv.lock b/RNA-seq/renv.lock
index 1dc855ca..8715cc54 100644
--- a/RNA-seq/renv.lock
+++ b/RNA-seq/renv.lock
@@ -77,10 +77,10 @@
     },
     "BH": {
       "Package": "BH",
-      "Version": "1.81.0-1",
+      "Version": "1.84.0-0",
       "Source": "Repository",
-      "Repository": "CRAN",
-      "Hash": "68122010f01c4dcfbe58ce7112f2433d"
+      "Repository": "RSPM",
+      "Hash": "a8235afbcd6316e6e91433ea47661013"
     },
     "Biobase": {
       "Package": "Biobase",
@@ -223,14 +223,14 @@
     },
     "DBI": {
       "Package": "DBI",
-      "Version": "1.2.0",
+      "Version": "1.2.1",
       "Source": "Repository",
       "Repository": "RSPM",
       "Requirements": [
         "R",
         "methods"
       ],
-      "Hash": "3e0051431dff9acfe66c23765e55c556"
+      "Hash": "9b4993e98e0e19da84c168460c032fef"
     },
     "DESeq2": {
       "Package": "DESeq2",
@@ -403,9 +403,9 @@
     },
     "MASS": {
       "Package": "MASS",
-      "Version": "7.3-60",
+      "Version": "7.3-60.0.1",
       "Source": "Repository",
-      "Repository": "CRAN",
+      "Repository": "RSPM",
       "Requirements": [
         "R",
         "grDevices",
@@ -414,11 +414,11 @@
         "stats",
         "utils"
       ],
-      "Hash": "a56a6365b3fa73293ea8d084be0d9bb0"
+      "Hash": "b765b28387acc8ec9e9c1530713cb19c"
     },
     "Matrix": {
       "Package": "Matrix",
-      "Version": "1.6-4",
+      "Version": "1.6-5",
       "Source": "Repository",
       "Repository": "RSPM",
       "Requirements": [
@@ -431,7 +431,7 @@
         "stats",
         "utils"
       ],
-      "Hash": "d9c655b30a2edc6bb2244c1d1e8d549d"
+      "Hash": "8c7115cd3a0e048bda2a7cd110549f7a"
     },
     "MatrixGenerics": {
       "Package": "MatrixGenerics",
@@ -553,7 +553,7 @@
     },
     "RCurl": {
       "Package": "RCurl",
-      "Version": "1.98-1.13",
+      "Version": "1.98-1.14",
       "Source": "Repository",
       "Repository": "RSPM",
       "Requirements": [
@@ -561,7 +561,7 @@
         "bitops",
         "methods"
       ],
-      "Hash": "318c7b8d68358b45cbc6115dda23d7db"
+      "Hash": "47f648d288079d0c696804ad4e55197e"
     },
     "RSQLite": {
       "Package": "RSQLite",
@@ -584,14 +584,14 @@
     },
     "Rcpp": {
       "Package": "Rcpp",
-      "Version": "1.0.11",
+      "Version": "1.0.12",
       "Source": "Repository",
-      "Repository": "CRAN",
+      "Repository": "RSPM",
       "Requirements": [
         "methods",
         "utils"
       ],
-      "Hash": "ae6cbbe1492f4de79c45fce06f967ce8"
+      "Hash": "5ea2700d21e038ace58269ecdbeb9ec0"
     },
     "RcppArmadillo": {
       "Package": "RcppArmadillo",
@@ -1210,14 +1210,14 @@
     },
     "digest": {
       "Package": "digest",
-      "Version": "0.6.33",
+      "Version": "0.6.34",
       "Source": "Repository",
-      "Repository": "CRAN",
+      "Repository": "RSPM",
       "Requirements": [
         "R",
         "utils"
       ],
-      "Hash": "b18a9cf3c003977b0cc49d5e76ebe48d"
+      "Hash": "7ede2ee9ea8d3edbf1ca84c1e333ad1a"
     },
     "doParallel": {
       "Package": "doParallel",
@@ -1536,7 +1536,7 @@
     },
     "ggrepel": {
       "Package": "ggrepel",
-      "Version": "0.9.4",
+      "Version": "0.9.5",
       "Source": "Repository",
       "Repository": "RSPM",
       "Requirements": [
@@ -1548,18 +1548,18 @@
         "scales",
         "withr"
       ],
-      "Hash": "e9839af82cc43fda486a638b68b439b2"
+      "Hash": "cc3361e234c4a5050e29697d675764aa"
     },
     "glue": {
       "Package": "glue",
-      "Version": "1.6.2",
+      "Version": "1.7.0",
       "Source": "Repository",
-      "Repository": "CRAN",
+      "Repository": "RSPM",
       "Requirements": [
         "R",
         "methods"
       ],
-      "Hash": "4f2596dfb05dac67b9dc558e5c6fba2e"
+      "Hash": "e0b3a53876554bd45879e596cdb10a52"
     },
     "gridExtra": {
       "Package": "gridExtra",
@@ -2150,7 +2150,7 @@
     },
     "pkgload": {
       "Package": "pkgload",
-      "Version": "1.3.3",
+      "Version": "1.3.4",
       "Source": "Repository",
       "Repository": "RSPM",
       "Requirements": [
@@ -2167,7 +2167,7 @@
         "utils",
         "withr"
       ],
-      "Hash": "903d68319ae9923fb2e2ee7fa8230b91"
+      "Hash": "876c618df5ae610be84356d5d7a5d124"
     },
     "plogr": {
       "Package": "plogr",
@@ -2178,7 +2178,7 @@
     },
     "plotly": {
       "Package": "plotly",
-      "Version": "4.10.3",
+      "Version": "4.10.4",
       "Source": "Repository",
       "Repository": "RSPM",
       "Requirements": [
@@ -2206,7 +2206,7 @@
         "vctrs",
         "viridisLite"
       ],
-      "Hash": "56914cc61df53f2d0283d5498680867e"
+      "Hash": "a1ac5c03ad5ad12b9d1597e00e23c3dd"
     },
     "plyr": {
       "Package": "plyr",
@@ -2302,14 +2302,14 @@
     },
     "ps": {
       "Package": "ps",
-      "Version": "1.7.5",
+      "Version": "1.7.6",
       "Source": "Repository",
-      "Repository": "CRAN",
+      "Repository": "RSPM",
       "Requirements": [
         "R",
         "utils"
       ],
-      "Hash": "709d852d33178db54b17c722e5b1e594"
+      "Hash": "dd2b9319ee0656c8acf45c7f40c59de7"
     },
     "purrr": {
       "Package": "purrr",
@@ -2398,14 +2398,14 @@
     },
     "rlang": {
       "Package": "rlang",
-      "Version": "1.1.2",
+      "Version": "1.1.3",
       "Source": "Repository",
       "Repository": "RSPM",
       "Requirements": [
         "R",
         "utils"
       ],
-      "Hash": "50a6dbdc522936ca35afc5e2082ea91b"
+      "Hash": "42548638fae05fd9a9b5f3f437fbbbe2"
     },
     "rmarkdown": {
       "Package": "rmarkdown",
@@ -2605,9 +2605,9 @@
     },
     "shinyWidgets": {
       "Package": "shinyWidgets",
-      "Version": "0.8.0",
+      "Version": "0.8.1",
       "Source": "Repository",
-      "Repository": "CRAN",
+      "Repository": "RSPM",
       "Requirements": [
         "R",
         "anytime",
@@ -2619,7 +2619,7 @@
         "sass",
         "shiny"
       ],
-      "Hash": "c6acc72327e63668bbc7bd258ee54132"
+      "Hash": "96bb249d21b7473dbeb0311702ef5288"
     },
     "shinycssloaders": {
       "Package": "shinycssloaders",
@@ -2786,25 +2786,23 @@
     },
     "teal.code": {
       "Package": "teal.code",
-      "Version": "0.4.1",
+      "Version": "0.5.0",
       "Source": "GitHub",
       "RemoteType": "github",
       "RemoteHost": "api.github.com",
       "RemoteUsername": "insightsengineering",
       "RemoteRepo": "teal.code",
-      "RemoteRef": "v0.4.1",
-      "RemoteSha": "7b14c0ae5579dc489b062a697b7fd756b324449e",
+      "RemoteRef": "v0.5.0",
+      "RemoteSha": "74d490ed2c34346d8b8cdf683e81b54b055e4a8f",
       "Requirements": [
         "R",
         "checkmate",
         "grDevices",
         "lifecycle",
         "methods",
-        "rlang",
-        "shiny",
-        "styler"
+        "rlang"
       ],
-      "Hash": "b78bea6a04fa52360afc602a5b5a3288"
+      "Hash": "e15fe6d14793e10d9105d8e8e5910eda"
     },
     "teal.data": {
       "Package": "teal.data",
@@ -3247,16 +3245,15 @@
     },
     "withr": {
       "Package": "withr",
-      "Version": "2.5.2",
+      "Version": "3.0.0",
       "Source": "Repository",
       "Repository": "RSPM",
       "Requirements": [
         "R",
         "grDevices",
-        "graphics",
-        "stats"
+        "graphics"
       ],
-      "Hash": "4b25e70111b7d644322e9513f403a272"
+      "Hash": "d31b6c62c10dcf11ec530ca6b0dd5d35"
     },
     "xfun": {
       "Package": "xfun",