diff --git a/src/anet.c b/src/anet.c
index 75471abd21..49334aa8e8 100644
--- a/src/anet.c
+++ b/src/anet.c
@@ -745,7 +745,7 @@ int anetFdToString(int fd, char *ip, size_t ip_len, int *port, int remote) {
  * and one of the use cases is O_CLOEXEC|O_NONBLOCK. */
 int anetPipe(int fds[2], int read_flags, int write_flags) {
     int pipe_flags = 0;
-#if defined(__linux__) || defined(__FreeBSD__)
+#ifdef HAVE_PIPE2
     /* When possible, try to leverage pipe2() to apply flags that are common to both ends.
      * There is no harm to set O_CLOEXEC to prevent fd leaks. */
     pipe_flags = O_CLOEXEC | (read_flags & write_flags);
diff --git a/src/config.h b/src/config.h
index 4646f653ea..2ff920a2a2 100644
--- a/src/config.h
+++ b/src/config.h
@@ -106,6 +106,15 @@
 #define HAVE_ACCEPT4 1
 #endif
 
+/* Detect for pipe2() */
+#if defined(__linux__) || \
+    defined(__FreeBSD__) || \
+    defined(OpenBSD5_7) || \
+    (defined(__DragonFly__) && __DragonFly_version >= 400106) || \
+    (defined(__NetBSD__) && (defined(NetBSD6_0) || __NetBSD_Version__ >= 600000000))
+#define HAVE_PIPE2 1
+#endif
+
 #if (defined(__APPLE__) && defined(MAC_OS_10_6_DETECTED)) || defined(__FreeBSD__) || defined(__OpenBSD__) || defined (__NetBSD__)
 #define HAVE_KQUEUE 1
 #endif