diff --git a/CHANGELOG.md b/CHANGELOG.md
index 7d31e967d..95ff3e43c 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -6,6 +6,7 @@
 - Add the image converter to the extra requires ([#677](../../pull/677))
 - All file tile sources can take either strings or pathlib.Path values ([#683](../../pull/683))
 - On Girder with read-only assetstores, return results even if caching fails ([#684](../../pull/684))
+- Handle geospatial files with no explicit projection ([#686](../../pull/686))
 
 ## Version 1.8.6
 
diff --git a/large_image/tilesource/__init__.py b/large_image/tilesource/__init__.py
index 310703679..6a3a43549 100644
--- a/large_image/tilesource/__init__.py
+++ b/large_image/tilesource/__init__.py
@@ -35,6 +35,8 @@ def isGeospatial(path):
         return True
     if ds.GetProjection():
         return True
+    if ds.GetGeoTransform(can_return_null=True):
+        return True
     if ds.GetDriver().ShortName in {'NITF', 'netCDF'}:
         return True
     return False
diff --git a/sources/gdal/large_image_source_gdal/__init__.py b/sources/gdal/large_image_source_gdal/__init__.py
index 514396391..db1ce299d 100644
--- a/sources/gdal/large_image_source_gdal/__init__.py
+++ b/sources/gdal/large_image_source_gdal/__init__.py
@@ -372,7 +372,8 @@ def getProj4String(self):
             else:
                 wkt = self.dataset.GetProjection()
         if not wkt:
-            if hasattr(self, '_netcdf') or self._getDriver() in {'NITF'}:
+            if (self.dataset.GetGeoTransform(can_return_null=True) or
+                    hasattr(self, '_netcdf') or self._getDriver() in {'NITF'}):
                 return NeededInitPrefix + 'epsg:4326'
             return
         proj = osr.SpatialReference()
@@ -569,6 +570,7 @@ def getMetadata(self):
                 'geospatial': bool(
                     self.dataset.GetProjection() or
                     (self.dataset.GetGCPProjection() and self.dataset.GetGCPs()) or
+                    self.dataset.GetGeoTransform(can_return_null=True) or
                     hasattr(self, '_netcdf')),
                 'levels': self.levels,
                 'sizeX': self.sizeX,
diff --git a/test/datastore.py b/test/datastore.py
index c49e189cb..0eb10049e 100644
--- a/test/datastore.py
+++ b/test/datastore.py
@@ -69,6 +69,9 @@
     # One layer tiff with missing tiles
     # Source: one_layer_missing_tiles.tiff
     'one_layer_missing_tiles.tiff': 'sha512:53d52abbb82d312b114407d2974fa0a4116c3b50875c5b360798b5d529cbb67596b1dff7d8feceb319d0b4377d12d023b64e374ea3df37f795c5a940afaa4cd5',  # noqa
+    # Geospatial file without a projection
+    # Source: generated from geojs oahu sample and a script
+    'oahu-dense.tiff': 'sha512:414b7807f14991d6f8229134ad6ccbc2cc2d4b05423ccebfd3ede7d7323dfcf04ef1a7b2c2b4c45c31f8a36bccd390782af3e7d3e99f01f1b95650c5da1f122b',  # noqa
 }
 
 
diff --git a/test/test_source_base.py b/test/test_source_base.py
index 2b8fa8e58..d1693ccc0 100644
--- a/test/test_source_base.py
+++ b/test/test_source_base.py
@@ -35,7 +35,7 @@
     'openjpeg': {'read': r'\.(jp2)$'},
     'openslide': {
         'read': r'\.(ptif|svs|tif.*)$',
-        'noread': r'(DDX58_AXL|huron\.image2_jpeg2k|landcover_sample|d042-353\.crop)',
+        'noread': r'(oahu|DDX58_AXL|huron\.image2_jpeg2k|landcover_sample|d042-353\.crop)',
         'skipTiles': r'one_layer_missing'},
     'pil': {
         'read': r'\.(jpeg|png|tif.*)$',
@@ -43,7 +43,8 @@
     'test': {'any': True, 'skipTiles': r''},
     'tiff': {
         'read': r'\.(ptif|scn|svs|tif.*)$',
-        'noread': r'(DDX58_AXL|G10-3_pelvis_crop|d042-353\.crop\.small\.float|landcover_sample)',
+        'noread': r'(oahu|DDX58_AXL|G10-3_pelvis_crop|'
+                  r'd042-353\.crop\.small\.float|landcover_sample)',
         'skipTiles': r'(sample_image\.ptif|one_layer_missing_tiles)'},
 }
 
diff --git a/test/test_source_gdal.py b/test/test_source_gdal.py
index bcdb4e532..ec298d5d5 100644
--- a/test/test_source_gdal.py
+++ b/test/test_source_gdal.py
@@ -496,3 +496,14 @@ def testGetTiledRegion16BitWithStyle():
     assert tileMetadata['bounds']['ymin'] == pytest.approx(3899358, 1)
     assert '+proj=merc' in tileMetadata['bounds']['srs']
     region.unlink()
+
+
+def testFileWithoutProjection():
+    imagePath = datastore.fetch('oahu-dense.tiff')
+    ts = large_image_source_gdal.open(imagePath, projection='EPSG:3857')
+    tileMetadata = ts.getMetadata()
+    assert tileMetadata['bounds']['xmax'] == pytest.approx(-17548722, 1)
+    assert tileMetadata['bounds']['xmin'] == pytest.approx(-17620245, 1)
+    assert tileMetadata['bounds']['ymax'] == pytest.approx(2477890, 1)
+    assert tileMetadata['bounds']['ymin'] == pytest.approx(2420966, 1)
+    assert 'epsg:3857' in tileMetadata['bounds']['srs']