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DESCRIPTION
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DESCRIPTION
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Package: nlmixr
Type: Package
Title: Nonlinear Mixed Effects Models in Population PK/PD
Depends: R (>= 3.5)
Imports: Rcpp (>= 0.12.3), brew, parallel, lbfgsb3c,
dparser, methods, ggplot2, memoise, rex, minqa, Matrix,
n1qn1 (>= 6.0.1-10), fastGHQuad,
RxODE(>= 1.0.0-0), nlme, magrittr, sys, backports
Suggests:
Deriv,
Rvmmin,
broom.mixed,
crayon,
knitr,
data.table,
devtools,
digest,
dotwhisker,
dplyr,
expm,
flextable,
ggtext,
patchwork,
gridExtra,
huxtable,
lattice,
lbfgs,
lotri,
madness,
matrixcalc,
nloptr,
officer,
pkgdown,
reshape2,
rmarkdown,
testthat,
tidyr,
ucminf,
vpc (>= 1.0.0),
xgxr,
yaml,
xpose,
generics,
tibble,
checkmate,
cli,
symengine,
covr,
forecast,
latticeExtra
Version: 2.0.1
Authors@R: c(person("Matthew","Fidler",
role = "aut", email = "[email protected]",
comment=c(ORCID="0000-0001-8538-6691")),
person("Yuan", "Xiong",
role = "aut", email = "[email protected]"),
person("Rik", "Schoemaker",
role = "aut", email = "[email protected]",
comment=c(ORCID="0000-0002-7538-3005")),
person("Justin", "Wilkins",
role = "aut", email = "[email protected]",
comment=c(ORCID="0000-0002-7099-9396")),
person("Richard", "Hooijmaijers", email = "[email protected]",
role = "aut"),
person("Teun","Post",
role = "aut", email = "[email protected]"),
person("Wenping", "Wang",
role = c("aut", "cre"), email = "[email protected]"),
person("Robert","Leary", role = "ctb"),
person("Mirjam","Trame", role = "ctb"),
person("Hadley","Wickham", role = "ctb"),
person("Dirk","Eddelbuettel",
role = "cph", email = "[email protected]"),
person("Mason","McComb",
role = "aut", email = "[email protected]",
comment=c(ORCID="0000-0001-9871-8616")),
person("Johannes", "Pfeifer",role="ctb"),
person("Robert B.", "Schnabel",role="ctb"),
person("Elizabeth", "Eskow", role="ctb"),
person("Emmanuelle", "Comets", role="ctb", email="[email protected]"),
person("Audrey", "Lavenu", role="ctb"),
person("Marc", "Lavielle", role="ctb"),
person("David","Ardia",role = "cph"),
person("Bill", "Denney", role=c("ctb"),
email="[email protected]",
comment=c(ORCID="0000-0002-5759-428X")),
person("Daniel C.", "Dillon", role="ctb"),
person("Katharine","Mullen",role = "cph"),
person("Ben", "Goodrich", role = "ctb")
)
Description: Fit and compare nonlinear mixed-effects models in differential
equations with flexible dosing information commonly seen in pharmacokinetics
and pharmacodynamics (Almquist, Leander, and Jirstrand 2015
<doi:10.1007/s10928-015-9409-1>). Differential equation solving is
by compiled C code provided in the 'RxODE' package
(Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).
License: GPL (>=2)
NeedsCompilation: yes
LinkingTo: dparser(>= 0.1.8), RxODE(>= 1.0.0-0), RcppEigen (>= 0.3.3.3.0),
lbfgsb3c, Rcpp, BH, StanHeaders(>= 2.18.0), RcppArmadillo (>= 0.5.600.2.0)
URL: https://github.com/nlmixrdevelopment/nlmixr
LazyData: true
RoxygenNote: 7.1.1
Biarch: true
Packaged: 2018-04-30 01:43:13 UTC; annie
Maintainer: Wenping Wang <[email protected]>
Encoding: UTF-8