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HCA Adult Heart Project

This is the working repository for the processing and analysis of the HCA Heart data in collaboration with:

Teichmann Lab - Wellcome Sanger Institute - Cambridge, United Kingdom.
Hubner Lab - MDC - Berlin, Germany.
Noseda Lab - Imperial College London - London, United Kingdom.
Seidman Labs - Harvard Medical School - Boston, MA, United States.

The repository will host constributions from developers and analysts at Sanger as well as the collaborators in London, Berlin and Boston.

To have a working copy of the repository, just clone it on your working machine as follow:

git clone --recursive https://github.com/cartal/HCA_Heart.git

Repo structure

There are three main folders where files for the analysis have been stored:

  1. Archived: Which includes the scripts to run cellbender, as well as the notebooks for downsteam analyses - This was not used for the final analysis.
  2. Analysis: Contain the notebooks used in the analysis of the paper.
  3. Mapping: Contains the scripts for the mapping of the reads to reference GRCh38 using CellRanger-v3.0.2.