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For Transcript Segment objects, when choosing genomic coordinates and transcript, the UI indicates that coordinates should be 1-indexed. However, it looks like it is taking in inter-residue coordinates.
Steps to reproduce
Choose Transcript Segment, genomic coordinates and transcript
For transcript, enter NM_152263.3
For chromosome, enter NC_000001.11
For ending position, enter 154191901
Expected behavior
N/A
Current behavior
The Transcript Segment object reported exon 1 with an offset of 0. This is correct since the coordinate corresponds to the alt_start_i value for exon 1, and the transcript is on the negative strand, so this Transcript Segment includes all of exon 1. If the coordinate was 1-indexed, there would be a nonzero offset.
Possible reason(s)
No response
Suggested fix
Indicate that supplied coordinates should be inter-residue. This will also ensure compatibility with cool-seq-tool as its methods expect inter-residue coordinates by default.
Describe the bug
For Transcript Segment objects, when choosing genomic coordinates and transcript, the UI indicates that coordinates should be 1-indexed. However, it looks like it is taking in inter-residue coordinates.
Steps to reproduce
NM_152263.3
NC_000001.11
154191901
Expected behavior
N/A
Current behavior
The Transcript Segment object reported exon 1 with an offset of 0. This is correct since the coordinate corresponds to the
alt_start_i
value for exon 1, and the transcript is on the negative strand, so this Transcript Segment includes all of exon 1. If the coordinate was 1-indexed, there would be a nonzero offset.Possible reason(s)
No response
Suggested fix
Indicate that supplied coordinates should be inter-residue. This will also ensure compatibility with cool-seq-tool as its methods expect inter-residue coordinates by default.
Branch, commit, and/or version
Was looking at http://fusion-curation-dev-eb.us-east-2.elasticbeanstalk.com/assayed-fusion
Screenshots
No response
Environment details
Mac M1
Additional details
No response
Contribution
None
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