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Method used to make the pseudoreplicates #3

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LettAdam opened this issue Apr 26, 2024 · 1 comment
Open

Method used to make the pseudoreplicates #3

LettAdam opened this issue Apr 26, 2024 · 1 comment

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@LettAdam
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Hello,

I don't know if I missed it in the article or in the vignette but I'm wondering exactly how the pseudo replicates are made, in particular, when using a seurat object.

Thank you for your work.
@ChristophH
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Hi,
If no replicates are specified in the input, the cells in every group (cluster) are randomly split into sub-clusters (pseudo-replicates, by default 3 per group). The counts (from the "RNA" slot) are then summed per pseudo-replicate.

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@ChristophH @LettAdam