From c410d38e60315d2eee6ea28190c3ca89045af497 Mon Sep 17 00:00:00 2001 From: njbernstein Date: Tue, 30 Jun 2020 17:39:08 -0700 Subject: [PATCH] Update README.md --- README.md | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/README.md b/README.md index 851231b..01150da 100644 --- a/README.md +++ b/README.md @@ -1,6 +1,6 @@ # solo -- Doublet detection via semi-supervised deep learning ### Why -Cells subjected to single cell RNA-seq have been through a lot, and they'd really just like to be alone now, please. If they cannot escape the cell social scene, you end up sequencing RNA from more than one cell to a barcode, creating a *doublet* when you expected single cell profiles. https://www.biorxiv.org/content/10.1101/841981v1 +Cells subjected to single cell RNA-seq have been through a lot, and they'd really just like to be alone now, please. If they cannot escape the cell social scene, you end up sequencing RNA from more than one cell to a barcode, creating a *doublet* when you expected single cell profiles. https://www.cell.com/cell-systems/fulltext/S2405-4712(20)30195-2 **_solo_** is a neural network framework to classify doublets, so that you can remove them from your data and clean your single cell profile.