synthetic scRNA-Seq from cellular reprogramming network.ipynb

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   "metadata": {},
   "source": [
    "# Synthetic expression data from cellular reprogramming network"
   ]
  },
  {
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   "execution_count": 1,
   "id": "72038bcf",
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    "from IPython.display import display, HTML\n",
    "display(HTML(\"<style>.container { width:100% !important; }</style>\"))\n",
    "import warnings\n",
    "warnings.filterwarnings(\"ignore\")"
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   "id": "e1b0dd84",
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   "source": [
    "import pandas as pd\n",
    "import numpy as np\n",
    "import random\n",
    "from colomoto.minibn import * # for Boolean network manipulation\n",
    "import networkx as nx # for graph manipulation\n",
    "from scboolseq import scBoolSeq\n",
    "\n",
    "from sklearn.decomposition import PCA\n",
    "\n",
    "import matplotlib.pyplot as plt\n",
    "from plotnine import *\n",
    "\n",
    "# set seed for reproducible results\n",
    "_rng_seed = 19834650\n",
    "# use a Generator instead of numpy's singleton\n",
    "_rng = np.random.default_rng(_rng_seed)\n",
    "random.seed(_rng_seed)"
   ]
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  {
   "cell_type": "code",
   "execution_count": 3,
   "id": "081ed8ca",
   "metadata": {},
   "outputs": [],
   "source": [
    "%matplotlib inline"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "2856557a",
   "metadata": {},
   "source": [
    "## Load Boolean network"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "id": "14973ce9",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "G1 <- TF1\n",
       "G2 <- TF1\n",
       "G3 <- TF1\n",
       "G4 <- TF2\n",
       "G5 <- TF2\n",
       "G6 <- TF2\n",
       "G7 <- TF6\n",
       "G8 <- TF6\n",
       "G9 <- TF6\n",
       "TF1 <- TF3&!TF2\n",
       "TF2 <- TF3&!TF1\n",
       "TF3 <- TF4\n",
       "TF4 <- TF5\n",
       "TF5 <- !TF6\n",
       "TF6 <- !TF7\n",
       "TF7 <- 1"
      ]
     },
     "execution_count": 4,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bn = BooleanNetwork.load(\"models/reprogramming.bnet\")\n",
    "bn"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "id": "909b46bd",
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "# computing graph layout...\n"
     ]
    },
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      "text/plain": [
       "<networkx.classes.multidigraph.MultiDiGraph at 0x7bb9d17dfd50>"
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     },
     "execution_count": 5,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "bn.influence_graph()"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "2784193c",
   "metadata": {},
   "source": [
    "## Extract trajectories from the state transition graph\n",
    "\n",
    "We consider the initial state where TF6 (and related G7-G9 genes) are active, as well as TF7 which will trigger the reprogramming."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 6,
   "id": "99951e02",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "{'G1': 0,\n",
       " 'G2': 0,\n",
       " 'G3': 0,\n",
       " 'G4': 0,\n",
       " 'G5': 0,\n",
       " 'G6': 0,\n",
       " 'G7': 1,\n",
       " 'G8': 1,\n",
       " 'G9': 1,\n",
       " 'TF1': 0,\n",
       " 'TF2': 0,\n",
       " 'TF3': 0,\n",
       " 'TF4': 0,\n",
       " 'TF5': 0,\n",
       " 'TF6': 1,\n",
       " 'TF7': 1}"
      ]
     },
     "execution_count": 6,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "initial_state = bn.zero()\n",
    "for node in [\"TF7\", \"TF6\", \"G7\", \"G8\", \"G9\"]:\n",
    "    initial_state[node] = 1\n",
    "initial_state"
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  {
   "cell_type": "markdown",
   "id": "0ac3aa18",
   "metadata": {},
   "source": [
    "We compute the state transition graph from the initial state, using the fully asynchronous update mode:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "id": "01fb9aba",
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "# computing graph layout...\n"
     ]
    },
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     },
     "execution_count": 7,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "dynamics = FullyAsynchronousDynamics(bn)\n",
    "stg = dynamics.partial_dynamics(initial_state)\n",
    "stg"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "8180d8bf",
   "metadata": {},
   "source": [
    "We can observe two stables states, both sharing TF7, and TF3-TF5 active, and one corresponding to TF1 active (and G1-G3), and one corresponding to TF2 (and G4-G6) active; the branching point is the state just before the activation of either TF1 or TF2.\n",
    "The deactivation of G1-G3 (resulting from the deactivation of TF6) is interleaved with the differentiation process. Thus the bifurcation point is not uniquely determined as in the previous example.\n"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "id": "37cdef5c",
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "init='0000001110000011'\n",
      "branching='0000000000011101'\n"
     ]
    }
   ],
   "source": [
    "# utility function to query the state-transition graph\n",
    "def node_of_state(state):\n",
    "    # convert a dict state to the binary representation\n",
    "    return \"\".join([str(state[node]) for node in dynamics.nodes])\n",
    "def extract_state(name):\n",
    "    # convert the binary representation of a state to a dict\n",
    "    return dict(zip(dynamics.nodes, map(int, name)))\n",
    "\n",
    "init = node_of_state(initial_state)\n",
    "print(f\"{init=}\")\n",
    "branching_active = [\"TF7\", \"TF3\", \"TF4\", \"TF5\"]\n",
    "branching = node_of_state({n: int(n in branching_active) for n in bn})\n",
    "print(f\"{branching=}\")"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "674251bc",
   "metadata": {},
   "source": [
    "We get the two stable states by computing the attractors of the state-transition graph:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "id": "a4289dac",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "['0001110000111101', '1110000001011101']"
      ]
     },
     "execution_count": 9,
     "metadata": {},
     "output_type": "execute_result"
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   ],
   "source": [
    "stables = [list(A)[0] for A in nx.attracting_components(stg)]\n",
    "stables.sort()\n",
    "stables # [0] is with TF2 active and [1] is with TF1 active"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "259ae0bb",
   "metadata": {},
   "source": [
    "Trajectory from initial state to first stable state:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 10,
   "id": "72e25fa3",
   "metadata": {},
   "outputs": [
    {
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       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch1.1</th>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch1.2</th>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>stable1</th>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch2.0</th>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch2.1</th>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch2.2</th>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>stable2</th>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>1</td>\n",
       "      <td>0</td>\n",
       "      <td>1</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "           G1  G2  G3  G4  G5  G6  G7  G8  G9  TF1  TF2  TF3  TF4  TF5  TF6  \\\n",
       "label                                                                         \n",
       "common.0    0   0   0   0   0   0   1   1   1    0    0    0    0    0    1   \n",
       "common.1    0   0   0   0   0   0   1   1   1    0    0    0    0    0    0   \n",
       "common.2    0   0   0   0   0   0   1   1   0    0    0    0    0    0    0   \n",
       "common.3    0   0   0   0   0   0   1   1   0    0    0    0    0    1    0   \n",
       "common.4    0   0   0   0   0   0   1   1   0    0    0    0    1    1    0   \n",
       "common.5    0   0   0   0   0   0   1   1   0    0    0    1    1    1    0   \n",
       "common.6    0   0   0   0   0   0   1   0   0    0    0    1    1    1    0   \n",
       "switch      0   0   0   0   0   0   0   0   0    0    0    1    1    1    0   \n",
       "branch1.0   0   0   0   0   0   0   0   0   0    1    0    1    1    1    0   \n",
       "branch1.1   1   0   0   0   0   0   0   0   0    1    0    1    1    1    0   \n",
       "branch1.2   1   1   0   0   0   0   0   0   0    1    0    1    1    1    0   \n",
       "stable1     1   1   1   0   0   0   0   0   0    1    0    1    1    1    0   \n",
       "branch2.0   0   0   0   0   0   0   0   0   0    0    1    1    1    1    0   \n",
       "branch2.1   0   0   0   1   0   0   0   0   0    0    1    1    1    1    0   \n",
       "branch2.2   0   0   0   1   1   0   0   0   0    0    1    1    1    1    0   \n",
       "stable2     0   0   0   1   1   1   0   0   0    0    1    1    1    1    0   \n",
       "\n",
       "           TF7  \n",
       "label           \n",
       "common.0     1  \n",
       "common.1     1  \n",
       "common.2     1  \n",
       "common.3     1  \n",
       "common.4     1  \n",
       "common.5     1  \n",
       "common.6     1  \n",
       "switch       1  \n",
       "branch1.0    1  \n",
       "branch1.1    1  \n",
       "branch1.2    1  \n",
       "stable1      1  \n",
       "branch2.0    1  \n",
       "branch2.1    1  \n",
       "branch2.2    1  \n",
       "stable2      1  "
      ]
     },
     "execution_count": 10,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "common = nx.shortest_path(stg, init, branching)\n",
    "traj1 = nx.shortest_path(stg, branching, stables[1])[1:]\n",
    "traj2 = nx.shortest_path(stg, branching, stables[0])[1:]\n",
    "binstates = pd.DataFrame(map(extract_state, common+traj1+traj2))\n",
    "\n",
    "# label the states\n",
    "labels = [f\"common.{i}\" for i in range(len(common)-1)] + [\"switch\"]\\\n",
    "         + [f\"branch1.{i}\" for i in range(len(traj1)-1)] + [\"stable1\"] \\\n",
    "         + [f\"branch2.{i}\" for i in range(len(traj2)-1)] + [\"stable2\"]\n",
    "binstates.index = labels\n",
    "binstates.index.name = \"label\"\n",
    "\n",
    "binstates"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "eb0f1873",
   "metadata": {},
   "source": [
    "We select the common path and two paths from the branching state to the stable states:"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "60eea3b1",
   "metadata": {},
   "source": [
    "## Retrieve reference dataset"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 11,
   "id": "9e662c61",
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "data_filtered_vargenes/GSE122466_Retina.csv\n",
      "data_filtered_vargenes/GSE122466_Retina_vargenes_batch1.csv\n",
      "data_filtered_vargenes/GSE130973_human_skin.csv\n",
      "data_filtered_vargenes/GSE156234_Macrophages.csv\n",
      "data_filtered_vargenes/GSE60361_mouse_brain.csv\n",
      "data_filtered_vargenes/GSE81682_Hematopoiesis.csv\n"
     ]
    }
   ],
   "source": [
    "%ls data_filtered_vargenes/*csv"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 12,
   "id": "d222afe7",
   "metadata": {},
   "outputs": [
    {
     "data": {
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       "      <th>Pomgnt2</th>\n",
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       "      <th>Rab20</th>\n",
       "      <th>Cd69</th>\n",
       "      <th>Gm2788</th>\n",
       "      <th>Gm14276</th>\n",
       "      <th>Napa</th>\n",
       "      <th>Cd24a</th>\n",
       "      <th>Nsun2</th>\n",
       "      <th>Marveld2</th>\n",
       "      <th>Ms4a4b</th>\n",
       "      <th>Gm17590</th>\n",
       "      <th>Cdk6</th>\n",
       "      <th>Tada2b</th>\n",
       "      <th>Gm5113</th>\n",
       "      <th>Mki67</th>\n",
       "      <th>Btg2</th>\n",
       "      <th>Gnat2</th>\n",
       "      <th>Tcaf1</th>\n",
       "      <th>Slc35e4</th>\n",
       "      <th>Reep2</th>\n",
       "      <th>8430419K02Rik</th>\n",
       "      <th>Pdgfd</th>\n",
       "      <th>H2-K1</th>\n",
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       "      <th>Tespa1</th>\n",
       "      <th>Wfdc17</th>\n",
       "      <th>Tspan13</th>\n",
       "      <th>Dyrk2</th>\n",
       "      <th>S100a9</th>\n",
       "      <th>F10</th>\n",
       "      <th>Pde1b</th>\n",
       "      <th>Gcnt2</th>\n",
       "      <th>Ppic</th>\n",
       "      <th>Zfp72</th>\n",
       "      <th>Gm4841</th>\n",
       "      <th>Ckb</th>\n",
       "      <th>C130013H08Rik</th>\n",
       "      <th>Spo11</th>\n",
       "      <th>Ctss</th>\n",
       "      <th>Vwa5a</th>\n",
       "      <th>Serpinb1a</th>\n",
       "      <th>Trib3</th>\n",
       "      <th>Slc28a2</th>\n",
       "      <th>Xbp1</th>\n",
       "      <th>Tsc22d3</th>\n",
       "      <th>Cd74</th>\n",
       "      <th>Nhlrc1</th>\n",
       "      <th>Rac2</th>\n",
       "      <th>Il15</th>\n",
       "      <th>Ift43</th>\n",
       "      <th>Tnfrsf13c</th>\n",
       "      <th>Gm10451</th>\n",
       "      <th>Plod2</th>\n",
       "      <th>Minpp1</th>\n",
       "      <th>Cs</th>\n",
       "      <th>Gm21967</th>\n",
       "      <th>Trim27</th>\n",
       "      <th>Rrm1</th>\n",
       "      <th>Krt18</th>\n",
       "      <th>Rap1b</th>\n",
       "      <th>Anxa2</th>\n",
       "      <th>D130040H23Rik</th>\n",
       "      <th>Tmsb4x</th>\n",
       "      <th>1810034E14Rik</th>\n",
       "      <th>2810021J22Rik</th>\n",
       "      <th>F630028O10Rik</th>\n",
       "      <th>Cyb5r3</th>\n",
       "      <th>B3gnt3</th>\n",
       "      <th>Laptm5</th>\n",
       "      <th>Adam11</th>\n",
       "      <th>Rab17</th>\n",
       "      <th>Pkia</th>\n",
       "      <th>Hist3h2ba</th>\n",
       "      <th>Cyp27a1</th>\n",
       "      <th>Zfp36</th>\n",
       "      <th>Mcm5</th>\n",
       "      <th>Ssc4d</th>\n",
       "      <th>Gm45837</th>\n",
       "      <th>Lmcd1</th>\n",
       "      <th>Fgf3</th>\n",
       "      <th>Car1</th>\n",
       "      <th>Adssl1</th>\n",
       "      <th>Il21r</th>\n",
       "      <th>Slc50a1</th>\n",
       "      <th>Serpinb9</th>\n",
       "      <th>Pttg1ip</th>\n",
       "      <th>Fam83d</th>\n",
       "      <th>Tspan32</th>\n",
       "      <th>Tnfrsf13b</th>\n",
       "      <th>Gdi2</th>\n",
       "      <th>Nim1k</th>\n",
       "      <th>Mapk12</th>\n",
       "      <th>Wfdc18</th>\n",
       "      <th>Thbs1</th>\n",
       "      <th>Chil5</th>\n",
       "      <th>Mpst</th>\n",
       "      <th>Selenop</th>\n",
       "      <th>Gm43852</th>\n",
       "      <th>Hk3</th>\n",
       "      <th>Irgm1</th>\n",
       "      <th>Nceh1</th>\n",
       "      <th>Myl10</th>\n",
       "      <th>Tmx1</th>\n",
       "      <th>Zcchc24</th>\n",
       "      <th>Acsl5</th>\n",
       "      <th>Tnfaip8</th>\n",
       "      <th>4632427E13Rik</th>\n",
       "      <th>Hspa9</th>\n",
       "      <th>Hid1</th>\n",
       "      <th>Gstt1</th>\n",
       "      <th>Il12rb1</th>\n",
       "      <th>Ficd</th>\n",
       "      <th>Bbs10</th>\n",
       "      <th>Esam</th>\n",
       "      <th>Unc93b1</th>\n",
       "      <th>Casp4</th>\n",
       "      <th>F2r</th>\n",
       "      <th>Dynlt3</th>\n",
       "      <th>Adgrg1</th>\n",
       "      <th>Tmem38a</th>\n",
       "      <th>Stap1</th>\n",
       "      <th>Cep170b</th>\n",
       "      <th>Lpxn</th>\n",
       "      <th>Frmd8</th>\n",
       "      <th>Doc2g</th>\n",
       "      <th>Ighv1-23</th>\n",
       "      <th>Hrh2</th>\n",
       "      <th>Bgn</th>\n",
       "      <th>Ifi206</th>\n",
       "      <th>Fes</th>\n",
       "      <th>Apol7e</th>\n",
       "      <th>Srl</th>\n",
       "      <th>Ifi47</th>\n",
       "      <th>Cdca7</th>\n",
       "      <th>Srm</th>\n",
       "      <th>Smagp</th>\n",
       "      <th>Zfp418</th>\n",
       "      <th>Zfp882</th>\n",
       "      <th>Mmp2</th>\n",
       "      <th>Fam32a</th>\n",
       "      <th>Flna</th>\n",
       "      <th>Lyz2</th>\n",
       "      <th>Cd53</th>\n",
       "      <th>Mapk11</th>\n",
       "      <th>Sptbn1</th>\n",
       "      <th>Mapre3</th>\n",
       "      <th>Nr0b2</th>\n",
       "      <th>Ptprc</th>\n",
       "      <th>Gulp1</th>\n",
       "      <th>Cd63</th>\n",
       "      <th>Nsg1</th>\n",
       "      <th>Fam131a</th>\n",
       "      <th>Dntt</th>\n",
       "      <th>Ifi213</th>\n",
       "      <th>Tcp1</th>\n",
       "      <th>Stard8</th>\n",
       "      <th>Clptm1l</th>\n",
       "      <th>Sigirr</th>\n",
       "      <th>Robo3</th>\n",
       "      <th>Il17rb</th>\n",
       "      <th>Mcfd2</th>\n",
       "      <th>Vpreb1</th>\n",
       "      <th>Casp12</th>\n",
       "      <th>Zbtb3</th>\n",
       "      <th>Ppt1</th>\n",
       "      <th>H1f0</th>\n",
       "      <th>C730034F03Rik</th>\n",
       "      <th>Tpst2</th>\n",
       "      <th>Pnrc1</th>\n",
       "      <th>Sdhaf2</th>\n",
       "      <th>Hnrnpdl</th>\n",
       "      <th>Cyp7b1</th>\n",
       "      <th>Ptpre</th>\n",
       "      <th>Slc25a45</th>\n",
       "      <th>Wdr35</th>\n",
       "      <th>Capg</th>\n",
       "      <th>Sf3b3</th>\n",
       "      <th>Gata1</th>\n",
       "      <th>Spry1</th>\n",
       "      <th>Abce1</th>\n",
       "      <th>Rnf180</th>\n",
       "      <th>Golph3l</th>\n",
       "      <th>P2ry10</th>\n",
       "      <th>Adgrg3</th>\n",
       "      <th>Fkbp4</th>\n",
       "      <th>F2rl2</th>\n",
       "      <th>Gbp2</th>\n",
       "      <th>Plcg2</th>\n",
       "      <th>Ccdc189</th>\n",
       "      <th>4930486L24Rik</th>\n",
       "      <th>E230001N04Rik</th>\n",
       "      <th>Itih5</th>\n",
       "      <th>Chrnb1</th>\n",
       "      <th>Gm16386</th>\n",
       "      <th>Thnsl2</th>\n",
       "      <th>Gm16712</th>\n",
       "      <th>Top2a</th>\n",
       "      <th>Gm5577</th>\n",
       "      <th>Nt5c3</th>\n",
       "      <th>Nlrp10</th>\n",
       "      <th>Ctf1</th>\n",
       "      <th>Il18bp</th>\n",
       "      <th>Il1rl2</th>\n",
       "      <th>Gm5148</th>\n",
       "      <th>Car2</th>\n",
       "      <th>Vim</th>\n",
       "      <th>A630033H20Rik</th>\n",
       "      <th>Cd81</th>\n",
       "      <th>Zfp563</th>\n",
       "      <th>Ctla2a</th>\n",
       "      <th>Mfsd2b</th>\n",
       "      <th>Idh2</th>\n",
       "      <th>Tert</th>\n",
       "      <th>Pwwp2b</th>\n",
       "      <th>Atp6ap2</th>\n",
       "      <th>Ces2g</th>\n",
       "      <th>Gba2</th>\n",
       "      <th>4931428F04Rik</th>\n",
       "      <th>Apoe</th>\n",
       "      <th>Sdha</th>\n",
       "      <th>Dlg3</th>\n",
       "      <th>Igkv4-50</th>\n",
       "      <th>Dhx58</th>\n",
       "      <th>Zfp661</th>\n",
       "      <th>Ccr9</th>\n",
       "      <th>Rgs2</th>\n",
       "      <th>Ctsc</th>\n",
       "      <th>Parp8</th>\n",
       "      <th>Tspo2</th>\n",
       "      <th>5430420F09Rik</th>\n",
       "      <th>Pear1</th>\n",
       "      <th>Ltb</th>\n",
       "      <th>Gm26512</th>\n",
       "      <th>AA467197</th>\n",
       "      <th>Unc5cl</th>\n",
       "      <th>Mtpn</th>\n",
       "      <th>Mcm6</th>\n",
       "      <th>Atp2a3</th>\n",
       "      <th>Tyms</th>\n",
       "      <th>Il12a</th>\n",
       "      <th>Celf2</th>\n",
       "      <th>Axl</th>\n",
       "      <th>Tpm4</th>\n",
       "      <th>Gm3739</th>\n",
       "      <th>Cyp2j9</th>\n",
       "      <th>Fxyd5</th>\n",
       "      <th>B230216N24Rik</th>\n",
       "      <th>Trbc2</th>\n",
       "      <th>Fam161b</th>\n",
       "      <th>Gm30948</th>\n",
       "      <th>Apbb1</th>\n",
       "      <th>Igfbp4</th>\n",
       "      <th>Pcp4l1</th>\n",
       "      <th>Rassf5</th>\n",
       "      <th>Cyp2r1</th>\n",
       "      <th>Smoc1</th>\n",
       "      <th>Srgn</th>\n",
       "      <th>Pygm</th>\n",
       "      <th>Gm43200</th>\n",
       "      <th>Gca</th>\n",
       "      <th>Arhgef6</th>\n",
       "      <th>Fah</th>\n",
       "      <th>BC017643</th>\n",
       "      <th>Ak3</th>\n",
       "      <th>Icam1</th>\n",
       "      <th>Gm10505</th>\n",
       "      <th>C1qbp</th>\n",
       "      <th>Efna1</th>\n",
       "      <th>AW112010</th>\n",
       "      <th>Tnks1bp1</th>\n",
       "      <th>Anxa1</th>\n",
       "      <th>Fgf11</th>\n",
       "      <th>Layn</th>\n",
       "      <th>Gm19331</th>\n",
       "      <th>Rbpms2</th>\n",
       "      <th>Tspan3</th>\n",
       "      <th>Ighv9-1</th>\n",
       "      <th>Gm43201</th>\n",
       "      <th>Arrdc1</th>\n",
       "      <th>Hjurp</th>\n",
       "      <th>4921507P07Rik</th>\n",
       "      <th>Sla</th>\n",
       "      <th>Ms4a6b</th>\n",
       "      <th>Zfp551</th>\n",
       "      <th>2810468N07Rik</th>\n",
       "      <th>Tnf</th>\n",
       "      <th>Serp1</th>\n",
       "      <th>Mfap2</th>\n",
       "      <th>Arhgef18</th>\n",
       "      <th>Slc25a29</th>\n",
       "      <th>Hmox1</th>\n",
       "      <th>Pkm</th>\n",
       "      <th>Arhgap15</th>\n",
       "      <th>Ddx39</th>\n",
       "      <th>Fv1</th>\n",
       "      <th>Gnb5</th>\n",
       "      <th>Tes</th>\n",
       "      <th>Lysmd2</th>\n",
       "      <th>Mmp11</th>\n",
       "      <th>Pgrmc1</th>\n",
       "      <th>Gm42979</th>\n",
       "      <th>Efna4</th>\n",
       "      <th>Uba7</th>\n",
       "      <th>Xist</th>\n",
       "      <th>Sumo3</th>\n",
       "      <th>Flt3</th>\n",
       "      <th>Mycn</th>\n",
       "      <th>1300017J02Rik</th>\n",
       "      <th>Scn1b</th>\n",
       "      <th>Rab38</th>\n",
       "      <th>ENSMUSG00000096970</th>\n",
       "      <th>Tnfaip2</th>\n",
       "      <th>Hdac2</th>\n",
       "      <th>Ccr7</th>\n",
       "      <th>Irf6</th>\n",
       "      <th>Mndal</th>\n",
       "      <th>Fut4</th>\n",
       "      <th>Casp1</th>\n",
       "      <th>Slc14a1</th>\n",
       "      <th>Rit1</th>\n",
       "      <th>Ifi203</th>\n",
       "      <th>Zfp93</th>\n",
       "      <th>Calr3</th>\n",
       "      <th>2210010C04Rik</th>\n",
       "      <th>Gm38243</th>\n",
       "      <th>Gm43313</th>\n",
       "      <th>Slc25a5</th>\n",
       "      <th>Bcam</th>\n",
       "      <th>Ighv1-74</th>\n",
       "      <th>Traf3ip3</th>\n",
       "      <th>Lgals9</th>\n",
       "      <th>Gm26982</th>\n",
       "      <th>Clec10a</th>\n",
       "      <th>Klhl8</th>\n",
       "      <th>Islr</th>\n",
       "      <th>Ighv1-76</th>\n",
       "      <th>Crlf3</th>\n",
       "      <th>Ighv1-77</th>\n",
       "      <th>Lcp2</th>\n",
       "      <th>Rapsn</th>\n",
       "      <th>Cd38</th>\n",
       "      <th>Gm37423</th>\n",
       "      <th>Selplg</th>\n",
       "      <th>Clip3</th>\n",
       "      <th>Ccdc157</th>\n",
       "      <th>Uggt2</th>\n",
       "      <th>Mpo</th>\n",
       "      <th>Eya1</th>\n",
       "      <th>Ctso</th>\n",
       "      <th>Gm26917</th>\n",
       "      <th>Rarb</th>\n",
       "      <th>Cmtm6</th>\n",
       "      <th>Metrnl</th>\n",
       "      <th>Rgs1</th>\n",
       "      <th>Ptpn6</th>\n",
       "      <th>Cd1d1</th>\n",
       "      <th>Lyrm1</th>\n",
       "      <th>Prkaa2</th>\n",
       "      <th>Gm4759</th>\n",
       "      <th>Aplp2</th>\n",
       "      <th>Gm8995</th>\n",
       "      <th>Gng11</th>\n",
       "      <th>Tmem150b</th>\n",
       "      <th>Abhd6</th>\n",
       "      <th>Gm5111</th>\n",
       "      <th>Ankrd50</th>\n",
       "      <th>Neurl3</th>\n",
       "      <th>Slc44a2</th>\n",
       "      <th>Gm128</th>\n",
       "      <th>Fam132a</th>\n",
       "      <th>2810414N06Rik</th>\n",
       "      <th>M6pr</th>\n",
       "      <th>Ankrd33b</th>\n",
       "      <th>Hexa</th>\n",
       "      <th>Pdcd1lg2</th>\n",
       "      <th>Dnajc9</th>\n",
       "      <th>Lck</th>\n",
       "      <th>Ccnb2</th>\n",
       "      <th>Wls</th>\n",
       "      <th>Gramd1a</th>\n",
       "      <th>Gm37642</th>\n",
       "      <th>St8sia4</th>\n",
       "      <th>Igkv12-44</th>\n",
       "      <th>Sqstm1</th>\n",
       "      <th>Slc25a35</th>\n",
       "      <th>Tipin</th>\n",
       "      <th>4930555A03Rik</th>\n",
       "      <th>Rn18s-rs5</th>\n",
       "      <th>Samd12</th>\n",
       "      <th>B9d1</th>\n",
       "      <th>Ncf4</th>\n",
       "      <th>Myc</th>\n",
       "      <th>Uaca</th>\n",
       "      <th>Irf9</th>\n",
       "      <th>Paics</th>\n",
       "      <th>Gstm1</th>\n",
       "      <th>Padi4</th>\n",
       "      <th>Tor3a</th>\n",
       "      <th>Rgs18</th>\n",
       "      <th>Slc26a6</th>\n",
       "      <th>Ppm1g</th>\n",
       "      <th>Zfand5</th>\n",
       "      <th>Smpd5</th>\n",
       "      <th>Hdac9</th>\n",
       "      <th>Gnl3</th>\n",
       "      <th>Ecm1</th>\n",
       "      <th>Rnase6</th>\n",
       "      <th>Lgals3bp</th>\n",
       "      <th>Slc2a10</th>\n",
       "      <th>Rdh14</th>\n",
       "      <th>Icos</th>\n",
       "      <th>Dnah1</th>\n",
       "      <th>Amt</th>\n",
       "      <th>Fut8</th>\n",
       "      <th>Itpkc</th>\n",
       "      <th>Ap1s2</th>\n",
       "      <th>Rgs11</th>\n",
       "      <th>Hpcal1</th>\n",
       "      <th>Gm43178</th>\n",
       "      <th>Rnase4</th>\n",
       "      <th>Adgrl4</th>\n",
       "      <th>Nek6</th>\n",
       "      <th>Clk1</th>\n",
       "      <th>Eya2</th>\n",
       "      <th>Csf3r</th>\n",
       "      <th>Fkbp1b</th>\n",
       "      <th>Pirb</th>\n",
       "      <th>Msmo1</th>\n",
       "      <th>Gm15133</th>\n",
       "      <th>Pim2</th>\n",
       "      <th>Cldn15</th>\n",
       "      <th>Gm28557</th>\n",
       "      <th>Ric8a</th>\n",
       "      <th>Triqk</th>\n",
       "      <th>Spns2</th>\n",
       "      <th>Cebpe</th>\n",
       "      <th>Tspan14</th>\n",
       "      <th>Itm2a</th>\n",
       "      <th>Ddx1</th>\n",
       "      <th>Sh3tc1</th>\n",
       "      <th>Slc22a18</th>\n",
       "      <th>Lcp1</th>\n",
       "      <th>Casp2</th>\n",
       "      <th>Epsti1</th>\n",
       "      <th>Ifi44</th>\n",
       "      <th>Phf11b</th>\n",
       "      <th>Ctsb</th>\n",
       "      <th>H2afy</th>\n",
       "      <th>Ctsg</th>\n",
       "      <th>Gimap9</th>\n",
       "      <th>Hsd3b7</th>\n",
       "      <th>Smpdl3a</th>\n",
       "      <th>Gm43162</th>\n",
       "      <th>Trim47</th>\n",
       "      <th>Cpa3</th>\n",
       "      <th>Cat</th>\n",
       "      <th>Cers2</th>\n",
       "      <th>Ifit3</th>\n",
       "      <th>Ifit1bl1</th>\n",
       "      <th>Slc9a3r2</th>\n",
       "      <th>Mcm3</th>\n",
       "      <th>Fscn1</th>\n",
       "      <th>Thbd</th>\n",
       "      <th>Cd93</th>\n",
       "      <th>Sept6</th>\n",
       "      <th>Irf5</th>\n",
       "      <th>Rab19</th>\n",
       "      <th>Ctsz</th>\n",
       "      <th>Rhbdf1</th>\n",
       "      <th>Wfs1</th>\n",
       "      <th>Mef2c</th>\n",
       "      <th>Blvrb</th>\n",
       "      <th>Gimap1</th>\n",
       "      <th>Gimap7</th>\n",
       "      <th>Gimap4</th>\n",
       "      <th>4930515G01Rik</th>\n",
       "      <th>Hgfac</th>\n",
       "      <th>Gimap6</th>\n",
       "      <th>Gm15201</th>\n",
       "      <th>Gimap5</th>\n",
       "      <th>BC035044</th>\n",
       "      <th>Ly6e</th>\n",
       "      <th>Hs3st1</th>\n",
       "      <th>Zfp62</th>\n",
       "      <th>Vpreb3</th>\n",
       "      <th>Kcnh2</th>\n",
       "      <th>Hn1l</th>\n",
       "      <th>Hlf</th>\n",
       "      <th>9930012K11Rik</th>\n",
       "      <th>Sgsm1</th>\n",
       "      <th>Gmpr</th>\n",
       "      <th>Lancl1</th>\n",
       "      <th>Slc16a1</th>\n",
       "      <th>Plcb2</th>\n",
       "      <th>Sdpr</th>\n",
       "      <th>Rhoh</th>\n",
       "      <th>Gm38250</th>\n",
       "      <th>Gm26532</th>\n",
       "      <th>Dock2</th>\n",
       "      <th>Pdlim2</th>\n",
       "      <th>Clk4</th>\n",
       "      <th>Nubp2</th>\n",
       "      <th>Treml2</th>\n",
       "      <th>Sell</th>\n",
       "      <th>Polm</th>\n",
       "      <th>Pglyrp2</th>\n",
       "      <th>Gm37829</th>\n",
       "      <th>Tsc22d1</th>\n",
       "      <th>9130008F23Rik</th>\n",
       "      <th>Gm37558</th>\n",
       "      <th>Gm37706</th>\n",
       "      <th>Ptprcap</th>\n",
       "      <th>Hck</th>\n",
       "      <th>Adamts10</th>\n",
       "      <th>Ly6a</th>\n",
       "      <th>Gm37598</th>\n",
       "      <th>Anxa5</th>\n",
       "      <th>Parvg</th>\n",
       "      <th>Acer2</th>\n",
       "      <th>Cd79a</th>\n",
       "      <th>Tmem175</th>\n",
       "      <th>Fcrl1</th>\n",
       "      <th>Dusp22</th>\n",
       "      <th>Ms4a4c</th>\n",
       "      <th>Bank1</th>\n",
       "      <th>Gm43149</th>\n",
       "      <th>Gatsl3</th>\n",
       "      <th>BC026585</th>\n",
       "      <th>Wfdc2</th>\n",
       "      <th>Camk1</th>\n",
       "      <th>Dgkq</th>\n",
       "      <th>Treml1</th>\n",
       "      <th>Ebi3</th>\n",
       "      <th>Gm27252</th>\n",
       "      <th>Magee1</th>\n",
       "      <th>Sdc2</th>\n",
       "      <th>Ldhb</th>\n",
       "      <th>Kmo</th>\n",
       "      <th>Bpifb5</th>\n",
       "      <th>Trim30a</th>\n",
       "      <th>Ifitm1</th>\n",
       "      <th>Ddx58</th>\n",
       "      <th>Ifitm3</th>\n",
       "      <th>Rmnd5b</th>\n",
       "      <th>Gm26772</th>\n",
       "      <th>Gm16151</th>\n",
       "      <th>Gm16150</th>\n",
       "      <th>Tagln2</th>\n",
       "      <th>3110083C13Rik</th>\n",
       "      <th>Cyp39a1</th>\n",
       "      <th>Tspyl3</th>\n",
       "      <th>Dennd1c</th>\n",
       "      <th>Slc2a1</th>\n",
       "      <th>Large1</th>\n",
       "      <th>AB124611</th>\n",
       "      <th>Gm17096</th>\n",
       "      <th>Stxbp4</th>\n",
       "      <th>Muc3a</th>\n",
       "      <th>Awat2</th>\n",
       "      <th>Plac8</th>\n",
       "      <th>AI506816</th>\n",
       "      <th>Canx</th>\n",
       "      <th>Alox5</th>\n",
       "      <th>Prdx6</th>\n",
       "      <th>F11r</th>\n",
       "      <th>Alg2</th>\n",
       "      <th>Lurap1</th>\n",
       "      <th>Ttc30b</th>\n",
       "      <th>Inpp5k</th>\n",
       "      <th>Dcdc2b</th>\n",
       "      <th>Tnfsf4</th>\n",
       "      <th>Atp6ap1</th>\n",
       "      <th>Dapp1</th>\n",
       "      <th>1500002C15Rik</th>\n",
       "      <th>Tuba4a</th>\n",
       "      <th>Gm43254</th>\n",
       "      <th>ENSMUSG00000029333</th>\n",
       "      <th>Gclm</th>\n",
       "      <th>Ruvbl2</th>\n",
       "      <th>Apobr</th>\n",
       "      <th>Nap1l3</th>\n",
       "      <th>Cct6a</th>\n",
       "      <th>Vav1</th>\n",
       "      <th>Rfc2</th>\n",
       "      <th>Gm16001</th>\n",
       "      <th>Atp1b1</th>\n",
       "      <th>Gm19708</th>\n",
       "      <th>Nradd</th>\n",
       "      <th>Ypel3</th>\n",
       "      <th>Tor4a</th>\n",
       "      <th>Gm19590</th>\n",
       "      <th>Ivns1abp</th>\n",
       "      <th>Gm15991</th>\n",
       "      <th>Upp1</th>\n",
       "      <th>Gm6157</th>\n",
       "      <th>Eif5a2</th>\n",
       "      <th>C1qtnf6</th>\n",
       "      <th>4933424M12Rik</th>\n",
       "      <th>Mageh1</th>\n",
       "      <th>Gm11696</th>\n",
       "      <th>Cbfb</th>\n",
       "      <th>Zfp422</th>\n",
       "      <th>Mfng</th>\n",
       "      <th>Klf8</th>\n",
       "      <th>Stk17b</th>\n",
       "      <th>Met</th>\n",
       "      <th>Ufsp1</th>\n",
       "      <th>Tmem150a</th>\n",
       "      <th>AI606181</th>\n",
       "      <th>Ikzf2</th>\n",
       "      <th>Slc34a2</th>\n",
       "      <th>1700066B19Rik</th>\n",
       "      <th>Mcm7</th>\n",
       "      <th>Fbxo48</th>\n",
       "      <th>Ecscr</th>\n",
       "      <th>Lyplal1</th>\n",
       "      <th>Ankrd37</th>\n",
       "      <th>Plek</th>\n",
       "      <th>Mapkbp1</th>\n",
       "      <th>Ppp1r3d</th>\n",
       "      <th>Exoc3l2</th>\n",
       "      <th>Tmem53</th>\n",
       "      <th>Wsb1</th>\n",
       "      <th>Rtkn</th>\n",
       "      <th>Tfr2</th>\n",
       "      <th>Leprot</th>\n",
       "      <th>Arhgap25</th>\n",
       "      <th>Nupr1</th>\n",
       "      <th>Plpp7</th>\n",
       "      <th>G730003C15Rik</th>\n",
       "      <th>Rsrp1</th>\n",
       "      <th>Samsn1</th>\n",
       "      <th>Prdx3</th>\n",
       "      <th>Gm37663</th>\n",
       "      <th>Itgb3</th>\n",
       "      <th>Rtn4r</th>\n",
       "      <th>Nrros</th>\n",
       "      <th>Dennd2d</th>\n",
       "      <th>Por</th>\n",
       "      <th>Tspear</th>\n",
       "      <th>Hsd17b12</th>\n",
       "      <th>Capza2</th>\n",
       "      <th>Osgin1</th>\n",
       "      <th>Spns3</th>\n",
       "      <th>Cd34</th>\n",
       "      <th>4921531C22Rik</th>\n",
       "      <th>Trmt2a</th>\n",
       "      <th>Gm26692</th>\n",
       "      <th>Col16a1</th>\n",
       "      <th>Cd46</th>\n",
       "      <th>Ptgds</th>\n",
       "      <th>Uqcrc1</th>\n",
       "      <th>Gm28512</th>\n",
       "      <th>Hacd4</th>\n",
       "      <th>Ttc39c</th>\n",
       "      <th>Igkv1-135</th>\n",
       "      <th>Fam129c</th>\n",
       "      <th>Rhof</th>\n",
       "      <th>Sdcbp</th>\n",
       "      <th>Rcsd1</th>\n",
       "      <th>Mmrn1</th>\n",
       "      <th>Ccser1</th>\n",
       "      <th>Ccdc92b</th>\n",
       "      <th>Tnfaip8l1</th>\n",
       "      <th>Tprgl</th>\n",
       "      <th>Gem</th>\n",
       "      <th>D630039A03Rik</th>\n",
       "      <th>Lrrc36</th>\n",
       "      <th>Map10</th>\n",
       "      <th>Gm38071</th>\n",
       "      <th>Ccng2</th>\n",
       "      <th>Ldha</th>\n",
       "      <th>Ramp1</th>\n",
       "      <th>Ucp2</th>\n",
       "      <th>Sdsl</th>\n",
       "      <th>Ttc4</th>\n",
       "      <th>Afap1l1</th>\n",
       "      <th>Ccnd2</th>\n",
       "      <th>Sult1a1</th>\n",
       "      <th>Ube2l6</th>\n",
       "      <th>Clec12a</th>\n",
       "      <th>Gm43643</th>\n",
       "      <th>Smtnl1</th>\n",
       "      <th>Aqp1</th>\n",
       "      <th>Large2</th>\n",
       "      <th>Creg1</th>\n",
       "      <th>Fam221a</th>\n",
       "      <th>Muc13</th>\n",
       "      <th>Slc25a11</th>\n",
       "      <th>Grap</th>\n",
       "      <th>Ncf1</th>\n",
       "      <th>B4galt4</th>\n",
       "      <th>Gm16758</th>\n",
       "      <th>Nucb1</th>\n",
       "      <th>Fam69b</th>\n",
       "      <th>Tmem35b</th>\n",
       "      <th>Mx1</th>\n",
       "      <th>Ppp1r26</th>\n",
       "      <th>Mx2</th>\n",
       "      <th>Ppp1r15a</th>\n",
       "      <th>Pdzk1ip1</th>\n",
       "      <th>Coro1a</th>\n",
       "      <th>Mob3c</th>\n",
       "      <th>Oas2</th>\n",
       "      <th>Kctd12b</th>\n",
       "      <th>Mefv</th>\n",
       "      <th>Gm12250</th>\n",
       "      <th>Sh2d5</th>\n",
       "      <th>Igtp</th>\n",
       "      <th>Ermap</th>\n",
       "      <th>Smu1</th>\n",
       "      <th>Maged2</th>\n",
       "      <th>Mcm4</th>\n",
       "      <th>Gm42576</th>\n",
       "      <th>Anxa6</th>\n",
       "      <th>1700123M08Rik</th>\n",
       "      <th>Rtp4</th>\n",
       "      <th>Sh3bgrl</th>\n",
       "      <th>Napsa</th>\n",
       "      <th>Kctd21</th>\n",
       "      <th>Chpf</th>\n",
       "      <th>Gm7160</th>\n",
       "      <th>Neurl1b</th>\n",
       "      <th>Cct3</th>\n",
       "      <th>Nkx2-3</th>\n",
       "      <th>Wdr78</th>\n",
       "      <th>Dusp1</th>\n",
       "      <th>Def8</th>\n",
       "      <th>Rbm5</th>\n",
       "      <th>BC016579</th>\n",
       "      <th>Emb</th>\n",
       "      <th>Elovl1</th>\n",
       "      <th>Myo1f</th>\n",
       "      <th>Lax1</th>\n",
       "      <th>Cyp2j6</th>\n",
       "      <th>Pstpip1</th>\n",
       "      <th>Emp1</th>\n",
       "      <th>Cd44</th>\n",
       "      <th>Mtch2</th>\n",
       "      <th>Pgm2</th>\n",
       "      <th>Krt7</th>\n",
       "      <th>Mir155hg</th>\n",
       "      <th>1110028F11Rik</th>\n",
       "      <th>Acot7</th>\n",
       "      <th>Rnd2</th>\n",
       "      <th>Irf1</th>\n",
       "      <th>H2-DMa</th>\n",
       "      <th>Zfp263</th>\n",
       "      <th>Rxra</th>\n",
       "      <th>Klhl6</th>\n",
       "      <th>A130014A01Rik</th>\n",
       "      <th>Ssbp2</th>\n",
       "      <th>Rbp1</th>\n",
       "      <th>Rsl1d1</th>\n",
       "      <th>Gjb3</th>\n",
       "      <th>Asah1</th>\n",
       "      <th>Tmem37</th>\n",
       "      <th>Spcs3</th>\n",
       "      <th>Cenpa</th>\n",
       "      <th>Gfpt2</th>\n",
       "      <th>Tmprss3</th>\n",
       "      <th>Pqlc3</th>\n",
       "      <th>Dhrs3</th>\n",
       "      <th>Jak3</th>\n",
       "      <th>Fam213b</th>\n",
       "      <th>Pafah2</th>\n",
       "      <th>Jun</th>\n",
       "      <th>Lamp1</th>\n",
       "      <th>Camsap3</th>\n",
       "      <th>Grtp1</th>\n",
       "      <th>Gm16794</th>\n",
       "      <th>Cacybp</th>\n",
       "      <th>Slfn8</th>\n",
       "      <th>Stom</th>\n",
       "      <th>H2-DMb1</th>\n",
       "      <th>H2-D1</th>\n",
       "      <th>Oas1c</th>\n",
       "      <th>Tas1r1</th>\n",
       "      <th>Rab44</th>\n",
       "      <th>4930579K19Rik</th>\n",
       "      <th>Fos</th>\n",
       "      <th>Nedd4</th>\n",
       "      <th>Cyb561</th>\n",
       "      <th>Mapkapk3</th>\n",
       "      <th>Inpp4b</th>\n",
       "      <th>Ccdc69</th>\n",
       "      <th>Slfn2</th>\n",
       "      <th>Tmem220</th>\n",
       "      <th>2610035D17Rik</th>\n",
       "      <th>Snap23</th>\n",
       "      <th>Nprl2</th>\n",
       "      <th>Rasal3</th>\n",
       "      <th>Ighv1-82</th>\n",
       "      <th>Batf</th>\n",
       "      <th>Tmem121</th>\n",
       "      <th>Rrm2</th>\n",
       "      <th>Surf4</th>\n",
       "      <th>Zfp386</th>\n",
       "      <th>Mamdc4</th>\n",
       "      <th>B230217C12Rik</th>\n",
       "      <th>Zbtb42</th>\n",
       "      <th>Sstr2</th>\n",
       "      <th>Pld2</th>\n",
       "      <th>Cers5</th>\n",
       "      <th>Ighd</th>\n",
       "      <th>Ighm</th>\n",
       "      <th>Cyp4v3</th>\n",
       "      <th>Limd2</th>\n",
       "      <th>Nlrp1a</th>\n",
       "      <th>H2-Q6</th>\n",
       "      <th>P4hb</th>\n",
       "      <th>Grn</th>\n",
       "      <th>H2-Q7</th>\n",
       "      <th>Gm10863</th>\n",
       "      <th>Hhex</th>\n",
       "      <th>Pcbp4</th>\n",
       "      <th>Tubb5</th>\n",
       "      <th>Itgb7</th>\n",
       "      <th>Gpam</th>\n",
       "      <th>Cbx5</th>\n",
       "      <th>Fam184a</th>\n",
       "      <th>Tmem106a</th>\n",
       "      <th>Adamtsl5</th>\n",
       "      <th>Cd79b</th>\n",
       "      <th>Nfe2</th>\n",
       "      <th>H2-Ob</th>\n",
       "      <th>Tcp11l2</th>\n",
       "      <th>Shisa5</th>\n",
       "      <th>Samd10</th>\n",
       "      <th>Hspa12b</th>\n",
       "      <th>Tcea2</th>\n",
       "      <th>Ctsd</th>\n",
       "      <th>Rgs19</th>\n",
       "      <th>Procr</th>\n",
       "      <th>Tnni2</th>\n",
       "      <th>Acap1</th>\n",
       "      <th>Bin2</th>\n",
       "      <th>Ropn1l</th>\n",
       "      <th>Lmbrd2</th>\n",
       "      <th>Laptm4b</th>\n",
       "      <th>Il7r</th>\n",
       "      <th>Capsl</th>\n",
       "      <th>Angpt1</th>\n",
       "      <th>Spag1</th>\n",
       "      <th>H2-Ab1</th>\n",
       "      <th>Gfi1b</th>\n",
       "      <th>H2-Aa</th>\n",
       "      <th>Ctsw</th>\n",
       "      <th>Hspa5</th>\n",
       "      <th>Tbc1d10c</th>\n",
       "      <th>Rom1</th>\n",
       "      <th>Smpd2</th>\n",
       "      <th>Ctsf</th>\n",
       "      <th>Fgd2</th>\n",
       "      <th>Cct8</th>\n",
       "      <th>Mamdc2</th>\n",
       "      <th>Stip1</th>\n",
       "      <th>Gm28043</th>\n",
       "      <th>Cd27</th>\n",
       "      <th>Rdh5</th>\n",
       "      <th>Aldoc</th>\n",
       "      <th>Prss57</th>\n",
       "      <th>Arpc1b</th>\n",
       "      <th>Fut7</th>\n",
       "      <th>Cd86</th>\n",
       "      <th>Serpinf1</th>\n",
       "      <th>Cd9</th>\n",
       "      <th>Gm37274</th>\n",
       "      <th>Wdr38</th>\n",
       "      <th>Angptl6</th>\n",
       "      <th>Smad6</th>\n",
       "      <th>Chad</th>\n",
       "      <th>Arhgdib</th>\n",
       "      <th>Eogt</th>\n",
       "      <th>Llgl2</th>\n",
       "      <th>Cst7</th>\n",
       "      <th>E130215H24Rik</th>\n",
       "      <th>Gm27201</th>\n",
       "      <th>Pcna</th>\n",
       "      <th>Rnf114</th>\n",
       "      <th>Gchfr</th>\n",
       "      <th>Cacfd1</th>\n",
       "      <th>Jam3</th>\n",
       "      <th>Fkbp1a</th>\n",
       "      <th>Eps8</th>\n",
       "      <th>Epb41l1</th>\n",
       "      <th>Traf1</th>\n",
       "      <th>Pdia3</th>\n",
       "      <th>Mgst1</th>\n",
       "      <th>Slc2a6</th>\n",
       "      <th>Spint1</th>\n",
       "      <th>Lmo2</th>\n",
       "      <th>Eng</th>\n",
       "      <th>Skap2</th>\n",
       "      <th>Vamp5</th>\n",
       "      <th>Plxna1</th>\n",
       "      <th>Klrb1f</th>\n",
       "      <th>Tmem176b</th>\n",
       "      <th>Mcm2</th>\n",
       "      <th>Slc52a3</th>\n",
       "      <th>Cct7</th>\n",
       "      <th>Ptgs1</th>\n",
       "      <th>Cnn2</th>\n",
       "      <th>Prim1</th>\n",
       "      <th>Rwdd2a</th>\n",
       "      <th>Matk</th>\n",
       "      <th>Atp5b</th>\n",
       "      <th>Cdk4</th>\n",
       "      <th>Robo4</th>\n",
       "      <th>Gm15915</th>\n",
       "      <th>Gm10101</th>\n",
       "      <th>Abhd4</th>\n",
       "      <th>Rab36</th>\n",
       "      <th>Metap2</th>\n",
       "      <th>Fzr1</th>\n",
       "      <th>Pa2g4</th>\n",
       "      <th>Smim24</th>\n",
       "      <th>Gm16104</th>\n",
       "      <th>Perp</th>\n",
       "      <th>Fig4</th>\n",
       "      <th>Myct1</th>\n",
       "      <th>Lsp1</th>\n",
       "      <th>Alpk3</th>\n",
       "      <th>Zfp28</th>\n",
       "      <th>Zfp78</th>\n",
       "      <th>Zfp773</th>\n",
       "      <th>Mill2</th>\n",
       "      <th>Gpr4</th>\n",
       "      <th>Nectin2</th>\n",
       "      <th>Tyrobp</th>\n",
       "      <th>Plekhf1</th>\n",
       "      <th>Nkg7</th>\n",
       "      <th>Osbpl1a</th>\n",
       "      <th>Slc27a6</th>\n",
       "      <th>Gm4951</th>\n",
       "      <th>Zfp438</th>\n",
       "      <th>Rab18</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>HSPC_025</th>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>5.392129</td>\n",
       "      <td>8.852337</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>2.614548</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.0</td>\n",
       "      <td>6.711045</td>\n",
       "      <td>7.977803</td>\n",
       "      <td>8.117451</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>8.195180</td>\n",
       "      <td>7.977803</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>9.173640</td>\n",
       "      <td>0.0</td>\n",
       "      <td>12.912375</td>\n",
       "      <td>8.427644</td>\n",
       "      <td>7.839405</td>\n",
       "      <td>0.0</td>\n",
       "      <td>1.189716</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>5.935712</td>\n",
       "      <td>0.0</td>\n",
       "      <td>8.021134</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>7.309000</td>\n",
       "      <td>10.293674</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>2.275971</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.0</td>\n",
       "      <td>9.014787</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>1.832751</td>\n",
       "      <td>8.774285</td>\n",
       "      <td>1.189716</td>\n",
       "      <td>1.189716</td>\n",
       "      <td>1.832751</td>\n",
       "      <td>0.0</td>\n",
       "      <td>3.118770</td>\n",
       "      <td>7.285499</td>\n",
       "      <td>0.0</td>\n",
       "      <td>7.135838</td>\n",
       "      <td>8.744431</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.0</td>\n",
       "      <td>8.852337</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
       "      <td>0.0</td>\n",
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       "LT-HSC_001            0.0   0.0     0.0  7.965715  5.885018  0.000000   \n",
       "HSPC_001              0.0   0.0     0.0  8.395500  0.000000  0.377367   \n",
       "\n",
       "             Fam107b  Gm14230   Plekhn1  Ankrd6  9030619P08Rik     Prtn3  \\\n",
       "HSPC_025    2.614548      0.0  0.000000     0.0       6.711045  7.977803   \n",
       "HSPC_031    6.838205      0.0  0.000000     0.0       8.951078  8.584765   \n",
       "HSPC_037    9.405107      0.0  0.000000     0.0       7.199831  9.495433   \n",
       "LT-HSC_001  8.962827      0.0  0.000000     0.0       2.364517  8.080749   \n",
       "HSPC_001    0.676211      0.0  0.676211     0.0       0.000000  8.923709   \n",
       "\n",
       "               Lrrn4  Mrgpre   Gm25926    Plppr3     Memo1    Cdkn1c  \\\n",
       "HSPC_025    8.117451     0.0  0.000000  8.195180  7.977803  0.000000   \n",
       "HSPC_031    0.000000     0.0  0.000000  6.956259  7.579348  0.000000   \n",
       "HSPC_037    0.000000     0.0  0.000000  7.394504  3.164226  0.000000   \n",
       "LT-HSC_001  0.000000     0.0  4.137438  3.749470  2.364517  0.000000   \n",
       "HSPC_001    0.377367     0.0  0.000000  8.851780  9.012407  7.123321   \n",
       "\n",
       "                Gm2a  Phxr4        B2m    Tbxas1    Glipr2  Tcf15    Trim58  \\\n",
       "HSPC_025    9.173640    0.0  12.912375  8.427644  7.839405    0.0  1.189716   \n",
       "HSPC_031    4.175851    0.0  13.622584  7.800662  0.000000    0.0  0.686872   \n",
       "HSPC_037    8.086368    0.0  13.104234  9.083711  8.014129    0.0  0.000000   \n",
       "LT-HSC_001  7.347331    0.0  13.944537  8.516418  3.749470    0.0  0.000000   \n",
       "HSPC_001    7.640356    0.0  12.746870  9.232729  9.914646    0.0  0.000000   \n",
       "\n",
       "            D930028M14Rik  1700010I14Rik   Gm10384      Sla2  Trp53i13  \\\n",
       "HSPC_025              0.0            0.0  0.000000  0.000000  5.935712   \n",
       "HSPC_031              0.0            0.0  0.686872  0.000000  0.000000   \n",
       "HSPC_037              0.0            0.0  0.000000  8.418471  0.000000   \n",
       "LT-HSC_001            0.0            0.0  0.000000  0.000000  0.000000   \n",
       "HSPC_001              0.0            0.0  5.069857  0.000000  0.000000   \n",
       "\n",
       "            Gm17586      Gypc     Clic5    Tubb4b  AC149090.1   Gm26580  \\\n",
       "HSPC_025        0.0  8.021134  0.000000  7.309000   10.293674  0.000000   \n",
       "HSPC_031        0.0  7.018651  1.150286  3.253543    7.387780  0.686872   \n",
       "HSPC_037        0.0  2.657566  0.000000  8.337902   10.692584  0.000000   \n",
       "LT-HSC_001      0.0  7.552600  0.000000  3.749470    9.893764  6.820748   \n",
       "HSPC_001        0.0  1.628905  0.000000  9.412471   11.118833  0.000000   \n",
       "\n",
       "              Clec1a      Ccl9    Gimap3  Zscan18      Spi1  Ccl6  \\\n",
       "HSPC_025    0.000000  2.275971  0.000000      0.0  9.014787   0.0   \n",
       "HSPC_031    0.000000  0.000000  0.000000      0.0  6.348589   0.0   \n",
       "HSPC_037    1.218731  8.500077  0.000000      0.0  8.308001   0.0   \n",
       "LT-HSC_001  2.364517  0.000000  0.000000      0.0  6.872760   0.0   \n",
       "HSPC_001    0.000000  0.676211  0.377367      0.0  6.802432   0.0   \n",
       "\n",
       "            2900041M22Rik      Klk8   Gm37637       Gp9     Idh3a   Akr1c13  \\\n",
       "HSPC_025         0.000000  0.000000  0.000000  1.832751  8.774285  1.189716   \n",
       "HSPC_031         0.686872  0.686872  0.000000  0.000000  2.827390  8.409573   \n",
       "HSPC_037         0.000000  7.275944  0.000000  0.000000  8.862937  0.000000   \n",
       "LT-HSC_001       0.000000  7.520353  0.000000  0.000000  2.364517  0.000000   \n",
       "HSPC_001         0.000000  4.414804  0.377367  7.107768  8.010188  5.867946   \n",
       "\n",
       "            2810408A11Rik      Npr2  Ephx1   Pik3ip1  ENSMUSG00000043858  \\\n",
       "HSPC_025         1.189716  1.832751    0.0  3.118770            7.285499   \n",
       "HSPC_031         0.686872  1.782055    0.0  8.765434            8.059983   \n",
       "HSPC_037         0.000000  1.218731    0.0  8.954567            2.316800   \n",
       "LT-HSC_001       0.000000  3.217169    0.0  7.232592            7.107933   \n",
       "HSPC_001         0.000000  9.303379    0.0  8.824449            1.134796   \n",
       "\n",
       "            Gm26789     Grina      Txnip   Gm26541  Dnajb3       Msn  Gm37124  \\\n",
       "HSPC_025        0.0  7.135838   8.744431  0.000000     0.0  8.852337      0.0   \n",
       "HSPC_031        0.0  8.638735   9.676164  0.686872     0.0  1.782055      0.0   \n",
       "HSPC_037        0.0  2.316800  11.106246  0.000000     0.0  8.510617      0.0   \n",
       "LT-HSC_001      0.0  8.564652  11.130502  0.000000     0.0  9.931038      0.0   \n",
       "HSPC_001        0.0  1.482235   8.987981  0.000000     0.0  1.318950      0.0   \n",
       "\n",
       "            Srd5a1  Bhlhe40   Pomgnt2    Fcer1g  Gm37298  Lmo1  Rab20  \\\n",
       "HSPC_025       0.0      0.0  1.832751  1.189716      0.0   0.0    0.0   \n",
       "HSPC_031       0.0      0.0  1.150286  1.150286      0.0   0.0    0.0   \n",
       "HSPC_037       0.0      0.0  1.869808  5.397461      0.0   0.0    0.0   \n",
       "LT-HSC_001     0.0      0.0  0.000000  7.584142      0.0   0.0    0.0   \n",
       "HSPC_001       0.0      0.0  0.377367  0.000000      0.0   0.0    0.0   \n",
       "\n",
       "                Cd69  Gm2788   Gm14276      Napa      Cd24a     Nsun2  \\\n",
       "HSPC_025    1.189716     0.0  0.000000  7.225016   8.876132  7.940672   \n",
       "HSPC_031    0.000000     0.0  0.000000  9.235683  10.222019  2.946297   \n",
       "HSPC_037    2.316800     0.0  0.000000  8.006701   9.250198  6.744074   \n",
       "LT-HSC_001  8.397178     0.0  5.095857  8.414827   9.184807  3.217169   \n",
       "HSPC_001    0.377367     0.0  0.000000  1.482235   7.239191  8.617097   \n",
       "\n",
       "            Marveld2    Ms4a4b  Gm17590       Cdk6    Tada2b  Gm5113  \\\n",
       "HSPC_025    6.184685  1.189716      0.0   8.691769  1.189716     0.0   \n",
       "HSPC_031    0.000000  0.000000      0.0   9.531507  0.000000     0.0   \n",
       "HSPC_037    1.869808  0.000000      0.0  10.085909  0.000000     0.0   \n",
       "LT-HSC_001  0.000000  2.364517      0.0   4.442877  0.000000     0.0   \n",
       "HSPC_001    0.000000  0.000000      0.0   2.921687  0.000000     0.0   \n",
       "\n",
       "               Mki67      Btg2  Gnat2  Tcaf1  Slc35e4     Reep2  \\\n",
       "HSPC_025    3.491677  7.161885    0.0    0.0      0.0  1.832751   \n",
       "HSPC_031    1.500480  0.686872    0.0    0.0      0.0  0.000000   \n",
       "HSPC_037    1.218731  6.928313    0.0    0.0      0.0  0.000000   \n",
       "LT-HSC_001  2.364517  0.000000    0.0    0.0      0.0  0.000000   \n",
       "HSPC_001    1.762030  0.000000    0.0    0.0      0.0  0.000000   \n",
       "\n",
       "            8430419K02Rik     Pdgfd      H2-K1     Sesn1    Bcap29   Gm21814  \\\n",
       "HSPC_025         6.779938  8.490658  11.925211  7.410259  3.317239  0.000000   \n",
       "HSPC_031         0.000000  0.000000  11.665664  9.216587  5.672502  0.000000   \n",
       "HSPC_037         0.000000  1.218731  12.131326  5.568630  8.093396  1.218731   \n",
       "LT-HSC_001       0.000000  0.000000  13.092126  4.137438  3.217169  0.000000   \n",
       "HSPC_001         0.000000  0.000000  12.396286  0.000000  0.676211  0.000000   \n",
       "\n",
       "                Eif5a     Stk25    Maged1    Zfp449  9130604C24Rik  \\\n",
       "HSPC_025    10.416407  4.242991  2.275971  1.832751       1.189716   \n",
       "HSPC_031     9.484386  0.000000  1.150286  0.000000       0.000000   \n",
       "HSPC_037    10.313640  2.657566  1.869808  1.218731       0.000000   \n",
       "LT-HSC_001   9.639814  3.217169  8.187283  0.000000       0.000000   \n",
       "HSPC_001    11.169149  0.377367  9.699115  0.000000       0.000000   \n",
       "\n",
       "            6430590A07Rik    Tcirg1       Il4   Slc35a4   Cysltr2  Ap3m2  \\\n",
       "HSPC_025         0.000000  7.894815  0.000000  9.681046  1.189716    0.0   \n",
       "HSPC_031         0.000000  0.000000  0.000000  6.991254  0.000000    0.0   \n",
       "HSPC_037         7.682451  1.869808  1.218731  2.933024  0.000000    0.0   \n",
       "LT-HSC_001       0.000000  3.749470  6.074609  2.364517  2.364517    0.0   \n",
       "HSPC_001         0.377367  0.000000  0.000000  8.285068  0.000000    0.0   \n",
       "\n",
       "            Dsel      Cmtm7     Arl8b      Gbx2  Smim10l2a     Cyth4  \\\n",
       "HSPC_025     0.0   9.723202  4.141925  0.000000        0.0  7.574401   \n",
       "HSPC_031     0.0   9.159273  3.158217  7.403453        0.0  8.372889   \n",
       "HSPC_037     0.0   9.998750  7.772788  0.000000        0.0  1.218731   \n",
       "LT-HSC_001   0.0   8.742914  8.888979  0.000000        0.0  0.000000   \n",
       "HSPC_001     0.0  11.201561  0.923649  0.377367        0.0  0.676211   \n",
       "\n",
       "               S1pr4      Gdi1  Hdhd3      Vill   Slc38a6      Calu   Gm16565  \\\n",
       "HSPC_025    7.174734  2.275971    0.0  2.614548  0.000000  2.888576  0.000000   \n",
       "HSPC_031    8.587055  1.500480    0.0  8.401790  0.686872  2.017546  0.686872   \n",
       "HSPC_037    1.218731  8.148427    0.0  1.218731  0.000000  2.657566  1.218731   \n",
       "LT-HSC_001  8.227787  3.217169    0.0  2.364517  0.000000  8.685906  0.000000   \n",
       "HSPC_001    5.216270  9.912410    0.0  8.639983  0.000000  2.374501  7.993360   \n",
       "\n",
       "               Smim3     Sar1a  4833407H14Rik  B230217O12Rik  Ccdc39  Spata2l  \\\n",
       "HSPC_025    7.806760  8.268934       3.491677            0.0     0.0      0.0   \n",
       "HSPC_031    0.686872  1.500480       7.574740            0.0     0.0      0.0   \n",
       "HSPC_037    8.621744  7.815920       0.000000            0.0     0.0      0.0   \n",
       "LT-HSC_001  7.271861  9.312700       8.914017            0.0     0.0      0.0   \n",
       "HSPC_001    0.000000  7.224846       0.676211            0.0     0.0      0.0   \n",
       "\n",
       "            Arxes2       Dut    Ifngr1     Rasa3     Fbxl2     Pde4b  \\\n",
       "HSPC_025       0.0  8.585122  2.888576  2.614548  0.000000  8.344797   \n",
       "HSPC_031       0.0  7.527841  3.342958  0.000000  1.150286  8.598449   \n",
       "HSPC_037       0.0  4.637700  8.546913  2.316800  0.000000  3.538458   \n",
       "LT-HSC_001     0.0  7.487369  4.909226  0.000000  0.000000  7.271861   \n",
       "HSPC_001       0.0  7.224846  9.392715  0.000000  0.000000  9.060862   \n",
       "\n",
       "              Ptp4a3      Cdt1     Fxyd1     Arl11    Shisa8  Dleu7   Tmem173  \\\n",
       "HSPC_025    6.461289  7.285499  0.000000  7.593666  6.657127    0.0  2.275971   \n",
       "HSPC_031    1.782055  1.782055  0.000000  0.686872  1.150286    0.0  2.219938   \n",
       "HSPC_037    8.592276  1.218731  0.000000  0.000000  1.218731    0.0  7.615671   \n",
       "LT-HSC_001  2.364517  3.217169  5.982925  0.000000  8.548753    0.0  4.137438   \n",
       "HSPC_001    1.628905  0.923649  0.000000  0.000000  4.434885    0.0  8.771148   \n",
       "\n",
       "              Atxn10       Rpn2      Ccl3    Nudt16     Kif3c      Hars  \\\n",
       "HSPC_025    8.655561   9.077708  0.000000  1.832751  1.189716  7.695253   \n",
       "HSPC_031    2.219938   9.404856  0.686872  1.150286  0.686872  2.017546   \n",
       "HSPC_037    1.218731   7.514567  8.833854  2.316800  1.218731  2.657566   \n",
       "LT-HSC_001  2.364517   3.749470  0.000000  2.364517  0.000000  3.749470   \n",
       "HSPC_001    1.628905  10.008081  8.286449  8.276747  8.061140  1.762030   \n",
       "\n",
       "                 Ccl4     Myo1g       Cpq  Cox6a2  Sdc3      Dok2     Fcgrt  \\\n",
       "HSPC_025    10.437884  1.832751  7.814991     0.0   0.0  1.189716  5.935712   \n",
       "HSPC_031     0.000000  0.686872  0.000000     0.0   0.0  7.824144  7.148337   \n",
       "HSPC_037     4.475001  6.943951  3.694521     0.0   0.0  1.218731  0.000000   \n",
       "LT-HSC_001   7.645229  2.364517  3.749470     0.0   0.0  3.217169  7.917005   \n",
       "HSPC_001     0.000000  8.663575  4.586200     0.0   0.0  8.923709  0.000000   \n",
       "\n",
       "               Elmo1      Cyc1      Calr  Gpr18    Tbxa2r    Gpr183  Naaa  \\\n",
       "HSPC_025    4.588530  2.275971  9.025466    0.0  1.189716  0.000000   0.0   \n",
       "HSPC_031    2.827390  2.397399  9.564413    0.0  6.623022  0.000000   0.0   \n",
       "HSPC_037    8.664848  6.490844  7.482801    0.0  5.647156  1.218731   0.0   \n",
       "LT-HSC_001  7.989468  7.674830  8.397178    0.0  2.364517  0.000000   0.0   \n",
       "HSPC_001    7.925790  1.482235  9.740544    0.0  8.240127  0.000000   0.0   \n",
       "\n",
       "            Gm11110      Alad       Taz    Echdc3    Cd300a  Slc39a4  Zfp128  \\\n",
       "HSPC_025        0.0  3.118771  1.189716  1.189716  7.161885      0.0     0.0   \n",
       "HSPC_031        0.0  2.397399  7.032157  0.000000  0.000000      0.0     0.0   \n",
       "HSPC_037        0.0  2.316800  1.218731  0.000000  0.000000      0.0     0.0   \n",
       "LT-HSC_001      0.0  8.207678  7.866592  0.000000  0.000000      0.0     0.0   \n",
       "HSPC_001        0.0  1.883902  8.577000  0.000000  0.000000      0.0     0.0   \n",
       "\n",
       "            Gm26819      Ispd      Itm2b  Zfp647  Gm16861  Nek3     Gata2  \\\n",
       "HSPC_025        0.0  0.000000  10.103505     0.0      0.0   0.0  2.888576   \n",
       "HSPC_031        0.0  0.000000  11.892010     0.0      0.0   0.0  1.782055   \n",
       "HSPC_037        0.0  0.000000  10.392692     0.0      0.0   0.0  7.160213   \n",
       "LT-HSC_001      0.0  0.000000  10.297362     0.0      0.0   0.0  7.584142   \n",
       "HSPC_001        0.0  7.520972   9.818564     0.0      0.0   0.0  0.000000   \n",
       "\n",
       "              Prss16    Lppos     Lhcgr    Fundc1       Lat  Tnfrsf26  \\\n",
       "HSPC_025    0.000000  0.00000  0.000000  7.977803  6.675324  0.000000   \n",
       "HSPC_031    0.000000  0.00000  1.150286  0.000000  7.828021  1.150286   \n",
       "HSPC_037    0.000000  0.00000  0.000000  2.316800  1.218731  8.355550   \n",
       "LT-HSC_001  0.000000  5.77998  0.000000  8.267186  4.137438  2.364517   \n",
       "HSPC_001    0.377367  0.00000  0.000000  0.377367  9.422563  0.377367   \n",
       "\n",
       "               Prr36     Vldlr     Mfge8     Enkur  Rcor2       Ndn      Btla  \\\n",
       "HSPC_025    0.000000  7.054751  0.000000  0.000000    0.0  0.000000  0.000000   \n",
       "HSPC_031    5.925034  0.000000  0.686872  0.000000    0.0  0.000000  0.686872   \n",
       "HSPC_037    0.000000  2.933024  0.000000  1.218731    0.0  0.000000  0.000000   \n",
       "LT-HSC_001  0.000000  2.364517  2.364517  0.000000    0.0  0.000000  0.000000   \n",
       "HSPC_001    0.000000  8.668884  0.377367  0.000000    0.0  5.918739  0.000000   \n",
       "\n",
       "                 Zyx      Cd33      Dkc1     Rab37     Cdcp1     Hoxa9  \\\n",
       "HSPC_025    9.101455  7.040782  9.449536  0.000000  0.000000  8.310278   \n",
       "HSPC_031    8.915083  0.000000  9.006865  8.155637  0.000000  9.640235   \n",
       "HSPC_037    8.669560  9.162687  9.873687  7.755167  1.218731  7.615671   \n",
       "LT-HSC_001  7.645229  3.217169  8.058464  7.107933  0.000000  7.232592   \n",
       "HSPC_001    4.265819  0.000000  9.042166  0.923649  0.000000  3.519027   \n",
       "\n",
       "                 Oat  Vegfc      Gas6     Oasl2     Tacc1  Colgalt1  Xdh  \\\n",
       "HSPC_025    8.495788    0.0  0.000000  2.888576  8.687292  7.940672  0.0   \n",
       "HSPC_031    2.397399    0.0  0.000000  2.017546  9.543345  0.686872  0.0   \n",
       "HSPC_037    1.218731    0.0  0.000000  8.626598  9.247050  2.316800  0.0   \n",
       "LT-HSC_001  7.760152    0.0  8.267186  4.137438  9.967373  0.000000  0.0   \n",
       "HSPC_001    8.720921    0.0  0.000000  8.950983  8.410789  0.676211  0.0   \n",
       "\n",
       "               Rab32      Dusp2  Tmem176a     Gnai3     Rnf13     Elane  \\\n",
       "HSPC_025    1.189716  11.307754  7.781782  7.894815  8.361752  0.000000   \n",
       "HSPC_031    0.000000   9.419062  9.750561  1.150286  0.686872  0.686872   \n",
       "HSPC_037    7.371559   6.779369  7.133183  1.869807  8.246273  0.000000   \n",
       "LT-HSC_001  8.187283   6.971475  8.926375  9.143059  7.063866  0.000000   \n",
       "HSPC_001    0.000000   0.676211  8.584884  6.136699  7.233470  1.628905   \n",
       "\n",
       "                Cd48    Mthfd1       Igkc      Fnta  Bok   Ripply3    Ptger2  \\\n",
       "HSPC_025    2.888576  9.067410   4.509590  8.310278  0.0  0.000000  0.000000   \n",
       "HSPC_031    6.549791  8.233698   3.653748  1.500480  0.0  0.000000  0.000000   \n",
       "HSPC_037    6.183499  7.348242   3.963623  8.808450  0.0  1.218731  1.218731   \n",
       "LT-HSC_001  3.749470  3.217169  12.461628  5.543737  0.0  0.000000  0.000000   \n",
       "HSPC_001    0.377367  1.996276   2.288830  9.442536  0.0  0.000000  0.000000   \n",
       "\n",
       "               P2rx7     Wdfy2     Eif1a     Gstm7   Tmem14c  2900018N21Rik  \\\n",
       "HSPC_025    0.000000  0.000000  7.343549  0.000000  5.671352       7.564672   \n",
       "HSPC_031    0.000000  0.000000  8.662811  0.000000  3.253543       0.000000   \n",
       "HSPC_037    1.218731  1.218731  7.914462  4.190334  7.133183       0.000000   \n",
       "LT-HSC_001  0.000000  0.000000  9.110936  0.000000  3.217169       0.000000   \n",
       "HSPC_001    0.000000  0.000000  6.111968  0.000000  2.604657       0.000000   \n",
       "\n",
       "                  Mpl     Sash3      Tgm2   Gm19569      Ehd3      Cish  \\\n",
       "HSPC_025    10.551846  6.763021  0.000000  1.189716  0.000000  0.000000   \n",
       "HSPC_031     2.219938  9.646834  0.000000  0.000000  0.000000  0.000000   \n",
       "HSPC_037     1.869807  6.813823  0.000000  0.000000  0.000000  1.218731   \n",
       "LT-HSC_001  10.136473  8.483344  0.000000  0.000000  2.364517  9.033078   \n",
       "HSPC_001    10.683373  8.965724  3.853357  0.000000  0.377367  0.000000   \n",
       "\n",
       "              Calml4    Mesdc2     Nfil3      Tcn2     Saraf     Meis1  \\\n",
       "HSPC_025    1.189716  9.272583  0.000000  1.189716  8.021134  8.150349   \n",
       "HSPC_031    0.000000  9.962022  0.686872  8.785511  9.802712  8.826781   \n",
       "HSPC_037    0.000000  9.162687  0.000000  6.689457  9.741228  7.605873   \n",
       "LT-HSC_001  0.000000  8.397178  0.000000  8.305537  8.466517  7.760152   \n",
       "HSPC_001    0.000000  1.482235  0.000000  0.000000  9.960822  7.587515   \n",
       "\n",
       "            Serpina3g       Pcx    Gpr171     Cks1b      Coa5  Arhgap27os3  \\\n",
       "HSPC_025     2.275971  0.000000  7.747791  8.130700  3.647281          0.0   \n",
       "HSPC_031     0.686872  0.000000  8.545278  2.697797  9.449579          0.0   \n",
       "HSPC_037     2.316800  1.218731  8.760682  3.363442  2.933024          0.0   \n",
       "LT-HSC_001   9.522611  0.000000  7.760152  2.364517  2.364517          0.0   \n",
       "HSPC_001     1.318950  0.000000  9.564895  7.530335  1.628905          0.0   \n",
       "\n",
       "               Farsa      Ctsl     Iigp1     P2ry14      Cd82   Slc18a2  \\\n",
       "HSPC_025    7.593666  1.832751  1.189716   7.790156  7.421084  0.000000   \n",
       "HSPC_031    8.201186  0.000000  0.000000   8.900430  2.397399  1.500480   \n",
       "HSPC_037    8.636256  7.160213  1.869807  10.783395  8.057904  0.000000   \n",
       "LT-HSC_001  4.137438  8.058464  4.909226   3.749470  3.749470  0.000000   \n",
       "HSPC_001    8.609387  8.121239  0.676211   8.514683  1.762030  0.377367   \n",
       "\n",
       "               Cd302    Parp12    Isyna1    S100a8  B130034C11Rik  Arhgap27  \\\n",
       "HSPC_025    0.000000  6.779938  2.275971  6.079295       0.000000  2.275971   \n",
       "HSPC_031    0.000000  0.686872  3.582099  0.000000       0.000000  3.506705   \n",
       "HSPC_037    0.000000  6.235258  3.164226  0.000000       0.000000  8.429623   \n",
       "LT-HSC_001  2.364517  8.700371  0.000000  0.000000       2.364517  8.080749   \n",
       "HSPC_001    0.000000  0.000000  1.628905  0.377367       0.000000  0.000000   \n",
       "\n",
       "                Klf1  Gm26740       Cd84      Bag2   Tmem123   Emilin1  \\\n",
       "HSPC_025    2.888576      0.0   9.014787  1.189716  8.182512  7.977803   \n",
       "HSPC_031    2.219938      0.0  10.152610  1.150286  6.348589  0.000000   \n",
       "HSPC_037    3.694520      0.0   1.869807  0.000000  7.710151  1.218731   \n",
       "LT-HSC_001  0.000000      0.0   8.532677  8.580378  7.674830  8.305537   \n",
       "HSPC_001    2.288830      0.0   1.628905  1.134796  1.134796  0.000000   \n",
       "\n",
       "            4930568A12Rik   Clec11a      Mat2a    Tespa1     Wfdc17  \\\n",
       "HSPC_025         4.141925  1.189716   9.826553  0.000000   9.822478   \n",
       "HSPC_031         0.000000  0.000000   7.780798  1.150286   1.150286   \n",
       "HSPC_037         0.000000  0.000000   9.498083  0.000000  10.651504   \n",
       "LT-HSC_001       0.000000  0.000000   4.137438  0.000000   7.645229   \n",
       "HSPC_001         0.000000  0.377367  10.135483  0.676211   1.318950   \n",
       "\n",
       "              Tspan13  Dyrk2    S100a9  F10  Pde1b     Gcnt2      Ppic  \\\n",
       "HSPC_025     8.594715    0.0  6.796659  0.0    0.0  7.273603  0.000000   \n",
       "HSPC_031     8.951078    0.0  0.000000  0.0    0.0  0.000000  0.000000   \n",
       "HSPC_037    10.660998    0.0  0.000000  0.0    0.0  7.482801  0.000000   \n",
       "LT-HSC_001   8.685906    0.0  0.000000  0.0    0.0  8.901552  2.364517   \n",
       "HSPC_001     8.785881    0.0  0.000000  0.0    0.0  7.854899  0.377367   \n",
       "\n",
       "               Zfp72    Gm4841       Ckb  C130013H08Rik     Spo11      Ctss  \\\n",
       "HSPC_025    4.141925  1.189716  6.845691       0.000000  1.189716  6.923879   \n",
       "HSPC_031    0.000000  0.000000  6.293577       8.896743  7.116992  0.686872   \n",
       "HSPC_037    0.000000  0.000000  0.000000       0.000000  0.000000  8.729440   \n",
       "LT-HSC_001  0.000000  2.364517  2.364517       0.000000  8.227787  5.885018   \n",
       "HSPC_001    0.000000  7.663942  0.000000       0.377367  0.000000  5.670382   \n",
       "\n",
       "               Vwa5a  Serpinb1a     Trib3   Slc28a2      Xbp1   Tsc22d3  \\\n",
       "HSPC_025    2.888576   5.776244  0.000000  0.000000  3.118771  8.475161   \n",
       "HSPC_031    8.445345   8.842198  0.000000  0.686872  7.045538  1.782055   \n",
       "HSPC_037    1.218731   8.854687  1.218731  0.000000  5.303604  9.218403   \n",
       "LT-HSC_001  0.000000   3.217169  5.982925  7.645229  5.543737  9.705823   \n",
       "HSPC_001    0.000000   7.499681  0.000000  0.000000  9.520952  9.448104   \n",
       "\n",
       "                 Cd74  Nhlrc1       Rac2      Il15     Ift43  Tnfrsf13c  \\\n",
       "HSPC_025     0.000000     0.0  10.807313  7.122636  0.000000   6.711045   \n",
       "HSPC_031     0.000000     0.0   8.900430  0.686872  1.500480   9.076959   \n",
       "HSPC_037     1.869807     0.0  11.052258  1.218731  0.000000   0.000000   \n",
       "LT-HSC_001  10.273376     0.0   9.438827  0.000000  0.000000   8.863498   \n",
       "HSPC_001     0.000000     0.0   8.703439  1.318950  6.563421   0.377367   \n",
       "\n",
       "            Gm10451     Plod2    Minpp1        Cs  Gm21967    Trim27  \\\n",
       "HSPC_025        0.0  4.242991  7.525084  2.275971      0.0  4.033241   \n",
       "HSPC_031        0.0  0.000000  2.219938  9.871007      0.0  8.938581   \n",
       "HSPC_037        0.0  0.000000  3.164226  6.156907      0.0  7.755167   \n",
       "LT-HSC_001      0.0  0.000000  8.166596  4.694814      0.0  3.217169   \n",
       "HSPC_001        0.0  0.000000  8.443370  1.318950      0.0  9.606986   \n",
       "\n",
       "                Rrm1     Krt18     Rap1b     Anxa2  D130040H23Rik     Tmsb4x  \\\n",
       "HSPC_025    9.167225  0.000000  3.317239  7.747791       0.000000   9.816341   \n",
       "HSPC_031    2.017546  6.977358  2.697797  1.150286       8.195195  10.778556   \n",
       "HSPC_037    2.933024  0.000000  2.933024  3.164226       0.000000   9.700377   \n",
       "LT-HSC_001  3.217169  8.516418  9.464477  2.364517       3.217169  10.330287   \n",
       "HSPC_001    6.723001  0.377367  8.671001  0.377367       0.000000  10.844519   \n",
       "\n",
       "            1810034E14Rik  2810021J22Rik  F630028O10Rik    Cyb5r3  B3gnt3  \\\n",
       "HSPC_025         0.000000       0.000000       0.000000  1.189716     0.0   \n",
       "HSPC_031         0.000000       0.000000       0.000000  2.017546     0.0   \n",
       "HSPC_037         0.000000       0.000000       8.977543  8.577312     0.0   \n",
       "LT-HSC_001       2.364517       2.364517       0.000000  2.364517     0.0   \n",
       "HSPC_001         0.000000       0.000000       0.676211  1.883902     0.0   \n",
       "\n",
       "               Laptm5    Adam11     Rab17     Pkia  Hist3h2ba  Cyp27a1  \\\n",
       "HSPC_025    10.088305  7.955639  0.000000  0.00000   0.000000      0.0   \n",
       "HSPC_031    10.784055  0.000000  0.000000  0.00000   5.004467      0.0   \n",
       "HSPC_037     9.332705  1.869807  0.000000  0.00000   0.000000      0.0   \n",
       "LT-HSC_001  10.442098  0.000000  7.107933  3.74947   5.885018      0.0   \n",
       "HSPC_001    10.464271  3.882894  0.000000  0.00000   0.000000      0.0   \n",
       "\n",
       "                Zfp36      Mcm5     Ssc4d   Gm45837  Lmcd1      Fgf3  \\\n",
       "HSPC_025    11.315027  7.631440  0.000000  0.000000    0.0  1.189716   \n",
       "HSPC_031     5.565109  3.506705  0.000000  0.000000    0.0  0.000000   \n",
       "HSPC_037     3.835337  2.933024  1.218731  1.218731    0.0  1.218731   \n",
       "LT-HSC_001   8.449492  2.364517  0.000000  0.000000    0.0  0.000000   \n",
       "HSPC_001     8.356553  1.482235  0.000000  7.281391    0.0  0.000000   \n",
       "\n",
       "                Car1    Adssl1     Il21r   Slc50a1  Serpinb9   Pttg1ip  \\\n",
       "HSPC_025    6.079295  8.356122  7.554876  9.390178  0.000000  7.887028   \n",
       "HSPC_031    5.706594  0.686872  7.135881  7.615685  0.000000  9.234223   \n",
       "HSPC_037    6.016053  7.348242  7.999236  8.367196  6.285223  8.531469   \n",
       "LT-HSC_001  4.442877  0.000000  7.192224  8.286489  3.217169  3.749470   \n",
       "HSPC_001    4.173225  8.508774  0.923649  7.330454  0.000000  9.775414   \n",
       "\n",
       "              Fam83d    Tspan32  Tnfrsf13b       Gdi2  Nim1k    Mapk12  \\\n",
       "HSPC_025    1.832751   9.681046   9.032541  10.105184    0.0  6.282898   \n",
       "HSPC_031    0.000000   9.659944   1.500480   8.627656    0.0  0.000000   \n",
       "HSPC_037    0.000000  10.283226   2.316800   7.930251    0.0  0.000000   \n",
       "LT-HSC_001  0.000000   9.312700   7.150694   8.595934    0.0  0.000000   \n",
       "HSPC_001    0.377367   8.996450   0.377367   9.137149    0.0  0.000000   \n",
       "\n",
       "              Wfdc18     Thbs1  Chil5  Mpst   Selenop   Gm43852       Hk3  \\\n",
       "HSPC_025    6.502641  3.787723    0.0   0.0  7.730490  0.000000  7.992392   \n",
       "HSPC_031    0.000000  2.017546    0.0   0.0  9.060576  0.000000  8.904107   \n",
       "HSPC_037    9.087235  0.000000    0.0   0.0  9.492777  0.000000  1.869807   \n",
       "LT-HSC_001  2.364517  2.364517    0.0   0.0  8.671295  0.000000  3.217169   \n",
       "HSPC_001    0.000000  0.000000    0.0   0.0  9.482276  7.088883  0.377367   \n",
       "\n",
       "               Irgm1     Nceh1     Myl10      Tmx1  Zcchc24     Acsl5  \\\n",
       "HSPC_025    7.902559  8.274914  7.668250  9.339726      0.0  8.063203   \n",
       "HSPC_031    1.782055  6.942020  8.069839  8.233698      0.0  4.631208   \n",
       "HSPC_037    6.864006  2.657566  1.869807  5.303604      0.0  7.336441   \n",
       "LT-HSC_001  8.058464  3.217169  2.364517  3.749470      0.0  8.166596   \n",
       "HSPC_001    1.318950  8.542711  7.809477  1.482235      0.0  9.920888   \n",
       "\n",
       "             Tnfaip8  4632427E13Rik     Hspa9  Hid1     Gstt1   Il12rb1  Ficd  \\\n",
       "HSPC_025    9.710022       1.189716  4.337438   0.0  7.593666  7.320609   0.0   \n",
       "HSPC_031    9.284465       6.783355  7.214989   0.0  0.000000  0.000000   0.0   \n",
       "HSPC_037    7.450320       1.869807  4.190334   0.0  0.000000  0.000000   0.0   \n",
       "LT-HSC_001  7.018409       7.150694  6.160812   0.0  0.000000  0.000000   0.0   \n",
       "HSPC_001    3.968042       1.318950  9.261827   0.0  0.000000  0.000000   0.0   \n",
       "\n",
       "            Bbs10      Esam   Unc93b1     Casp4       F2r    Dynlt3  \\\n",
       "HSPC_025      0.0  1.832751  7.871328  7.584065  1.189716  1.832751   \n",
       "HSPC_031      0.0  7.377236  0.686872  0.000000  0.686872  0.686872   \n",
       "HSPC_037      0.0  1.218731  9.111674  4.386210  1.869807  8.467986   \n",
       "LT-HSC_001    0.0  2.364517  4.442877  2.364517  0.000000  2.364517   \n",
       "HSPC_001      0.0  9.772458  6.786892  0.676211  0.676211  5.030808   \n",
       "\n",
       "               Adgrg1   Tmem38a     Stap1   Cep170b  Lpxn     Frmd8  Doc2g  \\\n",
       "HSPC_025    10.034692  0.000000  1.832751  3.317239   0.0  5.347433    0.0   \n",
       "HSPC_031    10.663397  0.000000  0.000000  0.000000   0.0  7.255855    0.0   \n",
       "HSPC_037     7.849521  0.000000  9.859326  0.000000   0.0  7.953614    0.0   \n",
       "LT-HSC_001  11.081615  4.137438  3.217169  3.749470   0.0  9.594069    0.0   \n",
       "HSPC_001    11.404691  0.000000  7.758600  7.079347   0.0  7.278616    0.0   \n",
       "\n",
       "            Ighv1-23  Hrh2       Bgn    Ifi206       Fes    Apol7e  Srl  \\\n",
       "HSPC_025         0.0   0.0  0.000000  5.634622  7.554876  6.502641  0.0   \n",
       "HSPC_031         0.0   0.0  0.686872  1.150286  4.021900  0.000000  0.0   \n",
       "HSPC_037         0.0   0.0  1.218731  0.000000  1.218731  0.000000  0.0   \n",
       "LT-HSC_001       0.0   0.0  2.364517  0.000000  2.364517  0.000000  0.0   \n",
       "HSPC_001         0.0   0.0  6.625896  0.000000  0.000000  0.000000  0.0   \n",
       "\n",
       "               Ifi47     Cdca7       Srm  Smagp    Zfp418    Zfp882      Mmp2  \\\n",
       "HSPC_025    7.640730  9.278547  8.971261    0.0  0.000000  7.012433  0.000000   \n",
       "HSPC_031    2.219938  3.849535  2.827391    0.0  0.000000  0.000000  8.467882   \n",
       "HSPC_037    6.813823  7.428252  3.164226    0.0  0.000000  0.000000  2.316800   \n",
       "LT-HSC_001  2.364517  3.217169  0.000000    0.0  0.000000  0.000000  0.000000   \n",
       "HSPC_001    9.288282  8.392936  9.193486    0.0  0.377367  0.000000  0.000000   \n",
       "\n",
       "              Fam32a      Flna       Lyz2       Cd53  Mapk11    Sptbn1  \\\n",
       "HSPC_025    8.035294  1.832751   9.438924   7.879200     0.0  6.159051   \n",
       "HSPC_031    9.385257  8.095797  10.225698   7.393023     0.0  9.179137   \n",
       "HSPC_037    8.907487  3.164226   4.386210  10.124163     0.0  9.413556   \n",
       "LT-HSC_001  8.532677  6.820749   9.979284   8.124310     0.0  6.461820   \n",
       "HSPC_001    0.923649  9.289661  10.363761   7.273049     0.0  4.099659   \n",
       "\n",
       "              Mapre3  Nr0b2     Ptprc     Gulp1      Cd63  Nsg1   Fam131a  \\\n",
       "HSPC_025    0.000000    0.0  8.028232  0.000000  8.156838   0.0  0.000000   \n",
       "HSPC_031    0.000000    0.0  1.782055  5.637585  8.561668   0.0  5.449074   \n",
       "HSPC_037    3.164226    0.0  9.759018  0.000000  1.218731   0.0  0.000000   \n",
       "LT-HSC_001  0.000000    0.0  5.261087  0.000000  8.305537   0.0  0.000000   \n",
       "HSPC_001    1.134796    0.0  2.977514  0.000000  9.935939   0.0  0.000000   \n",
       "\n",
       "                Dntt    Ifi213      Tcp1  Stard8   Clptm1l    Sigirr  \\\n",
       "HSPC_025    2.888576  1.832751  8.400554     0.0  4.426081  1.832751   \n",
       "HSPC_031    9.228369  4.223722  2.946297     0.0  6.380618  9.852094   \n",
       "HSPC_037    3.164226  0.000000  7.275944     0.0  7.238389  2.933024   \n",
       "LT-HSC_001  4.694814  0.000000  9.522611     0.0  8.124310  7.703835   \n",
       "HSPC_001    1.996276  0.000000  4.493504     0.0  1.134796  9.102259   \n",
       "\n",
       "               Robo3  Il17rb     Mcfd2    Vpreb1    Casp12  Zbtb3      Ppt1  \\\n",
       "HSPC_025    0.000000     0.0  9.345421  0.000000  0.000000    0.0  8.400554   \n",
       "HSPC_031    0.000000     0.0  9.311023  0.000000  0.686872    0.0  0.000000   \n",
       "HSPC_037    0.000000     0.0  3.164226  0.000000  1.869807    0.0  4.978682   \n",
       "LT-HSC_001  0.000000     0.0  0.000000  3.217169  3.217169    0.0  9.849024   \n",
       "HSPC_001    3.592379     0.0  0.923649  0.000000  7.607558    0.0  0.377367   \n",
       "\n",
       "                H1f0  C730034F03Rik     Tpst2     Pnrc1    Sdhaf2   Hnrnpdl  \\\n",
       "HSPC_025    3.118771            0.0  8.989556  7.174734  7.704143  7.273603   \n",
       "HSPC_031    7.273021            0.0  1.500480  9.495397  7.209055  3.427154   \n",
       "HSPC_037    9.915931            0.0  7.173540  2.933024  0.000000  9.615036   \n",
       "LT-HSC_001  7.674830            0.0  8.770595  6.652419  3.749470  2.364517   \n",
       "HSPC_001    0.377367            0.0  0.000000  3.995344  7.902545  9.643577   \n",
       "\n",
       "              Cyp7b1      Ptpre  Slc25a45     Wdr35      Capg     Sf3b3  \\\n",
       "HSPC_025    0.000000   8.433001  4.337438  0.000000  8.124090  9.656065   \n",
       "HSPC_031    0.000000  10.735345  6.022986  0.000000  7.565481  2.555402   \n",
       "HSPC_037    0.000000   8.678935  7.874218  3.164226  7.383077  2.316800   \n",
       "LT-HSC_001  0.000000   4.442877  3.217169  0.000000  4.442877  9.455977   \n",
       "HSPC_001    0.377367   0.923649  8.056288  0.000000  1.883902  1.628905   \n",
       "\n",
       "               Gata1  Spry1     Abce1  Rnf180   Golph3l    P2ry10    Adgrg3  \\\n",
       "HSPC_025    0.000000    0.0  7.095865     0.0  8.454235  0.000000  6.132952   \n",
       "HSPC_031    2.397399    0.0  8.570951     0.0  8.009667  8.874422  1.150286   \n",
       "HSPC_037    1.869807    0.0  2.316800     0.0  3.363442  0.000000  9.080177   \n",
       "LT-HSC_001  2.364517    0.0  3.749470     0.0  9.055756  0.000000  2.364517   \n",
       "HSPC_001    1.628905    0.0  8.057907     0.0  9.902980  0.676211  1.482235   \n",
       "\n",
       "               Fkbp4  F2rl2      Gbp2     Plcg2  Ccdc189  4930486L24Rik  \\\n",
       "HSPC_025    7.040782    0.0  0.000000  5.905197      0.0       0.000000   \n",
       "HSPC_031    9.864415    0.0  0.000000  6.984322      0.0       0.000000   \n",
       "HSPC_037    9.040723    0.0  0.000000  8.283626      0.0       0.000000   \n",
       "LT-HSC_001  9.264843    0.0  9.174482  9.530727      0.0       7.917005   \n",
       "HSPC_001    8.315172    0.0  0.000000  8.858300      0.0       0.000000   \n",
       "\n",
       "            E230001N04Rik     Itih5    Chrnb1  Gm16386  Thnsl2   Gm16712  \\\n",
       "HSPC_025         1.189716  7.839405  5.809578      0.0     0.0  7.297297   \n",
       "HSPC_031         0.000000  7.694245  0.000000      0.0     0.0  0.000000   \n",
       "HSPC_037         0.000000  1.218731  0.000000      0.0     0.0  0.000000   \n",
       "LT-HSC_001       0.000000  8.080749  3.217169      0.0     0.0  0.000000   \n",
       "HSPC_001         0.000000  3.083081  0.000000      0.0     0.0  0.000000   \n",
       "\n",
       "               Top2a    Gm5577     Nt5c3  Nlrp10      Ctf1  Il18bp    Il1rl2  \\\n",
       "HSPC_025    3.491677  0.000000  8.490658     0.0  0.000000     0.0  0.000000   \n",
       "HSPC_031    2.397399  0.686872  8.259764     0.0  0.000000     0.0  0.686872   \n",
       "HSPC_037    1.869807  0.000000  8.314031     0.0  0.000000     0.0  4.190334   \n",
       "LT-HSC_001  8.286489  0.000000  3.217169     0.0  0.000000     0.0  0.000000   \n",
       "HSPC_001    2.921687  0.000000  9.107741     0.0  0.377367     0.0  0.000000   \n",
       "\n",
       "              Gm5148       Car2       Vim  A630033H20Rik      Cd81    Zfp563  \\\n",
       "HSPC_025    0.000000  11.130318  8.207737       0.000000  8.993188  0.000000   \n",
       "HSPC_031    0.000000   9.967304  8.682216       0.000000  4.520574  5.723342   \n",
       "HSPC_037    0.000000  10.867803  1.218731       1.218731  8.014129  0.000000   \n",
       "LT-HSC_001  5.779980   8.227787  3.217169       0.000000  9.055756  0.000000   \n",
       "HSPC_001    6.608321  10.655834  1.628905       0.000000  9.932853  0.000000   \n",
       "\n",
       "              Ctla2a    Mfsd2b      Idh2  Tert  Pwwp2b   Atp6ap2     Ces2g  \\\n",
       "HSPC_025    9.521714  2.614548  9.882450   0.0     0.0  9.506549  2.275971   \n",
       "HSPC_031    8.989663  1.782055  2.827391   0.0     0.0  8.030005  3.342958   \n",
       "HSPC_037    9.506006  3.164226  7.472055   0.0     0.0  7.119476  3.164226   \n",
       "LT-HSC_001  8.414827  0.000000  7.453613   0.0     0.0  3.749470  2.364517   \n",
       "HSPC_001    8.069193  0.676211  8.487300   0.0     0.0  8.833932  1.628905   \n",
       "\n",
       "                Gba2  4931428F04Rik      Apoe      Sdha      Dlg3  Igkv4-50  \\\n",
       "HSPC_025    3.915699            0.0  6.923879  9.690023  1.189716       0.0   \n",
       "HSPC_031    0.000000            0.0  8.137007  2.017546  0.686872       0.0   \n",
       "HSPC_037    1.869807            0.0  2.316800  7.428252  0.000000       0.0   \n",
       "LT-HSC_001  0.000000            0.0  7.965715  6.971475  0.000000       0.0   \n",
       "HSPC_001    5.509264            0.0  2.604657  1.883902  8.511140       0.0   \n",
       "\n",
       "               Dhx58  Zfp661      Ccr9      Rgs2      Ctsc     Parp8  \\\n",
       "HSPC_025    0.000000     0.0  0.000000  7.285499  7.631440  3.118771   \n",
       "HSPC_031    0.686872     0.0  0.000000  8.477787  8.566318  6.502060   \n",
       "HSPC_037    4.558643     0.0  1.218731  9.457801  2.316800  2.316800   \n",
       "LT-HSC_001  0.000000     0.0  2.364517  9.078081  7.271861  2.364517   \n",
       "HSPC_001    7.281391     0.0  0.000000  0.377367  9.534391  0.676211   \n",
       "\n",
       "               Tspo2  5430420F09Rik     Pear1       Ltb  Gm26512  AA467197  \\\n",
       "HSPC_025    2.275971            0.0  7.161885  8.926381      0.0  1.189716   \n",
       "HSPC_031    1.500480            0.0  0.000000  1.500480      0.0  0.000000   \n",
       "HSPC_037    2.316800            0.0  1.218731  2.933024      0.0  0.000000   \n",
       "LT-HSC_001  0.000000            0.0  8.837559  9.021605      0.0  0.000000   \n",
       "HSPC_001    1.318950            0.0  0.676211  7.709989      0.0  0.000000   \n",
       "\n",
       "              Unc5cl      Mtpn       Mcm6    Atp2a3      Tyms     Il12a  \\\n",
       "HSPC_025    0.000000  9.342576  10.287772  5.742120  2.275971  8.350471   \n",
       "HSPC_031    0.686872  2.397399   3.253543  8.393966  2.017546  8.251127   \n",
       "HSPC_037    0.000000  9.855197   7.968982  1.869807  2.933024  9.090753   \n",
       "LT-HSC_001  0.000000  7.941566   8.548753  8.286489  0.000000  0.000000   \n",
       "HSPC_001    6.074058  0.923649   6.970060  0.676211  1.628905  1.134796   \n",
       "\n",
       "               Celf2       Axl      Tpm4  Gm3739    Cyp2j9     Fxyd5  \\\n",
       "HSPC_025    8.744431  7.847452  2.614548     0.0  1.189716  9.812235   \n",
       "HSPC_031    7.719509  0.000000  0.686872     0.0  1.500480  9.514768   \n",
       "HSPC_037    8.577312  1.218731  8.148427     0.0  8.320036  9.018738   \n",
       "LT-HSC_001  9.078081  0.000000  4.137438     0.0  7.347332  9.078081   \n",
       "HSPC_001    3.519027  0.000000  0.676211     0.0  8.524086  8.845230   \n",
       "\n",
       "            B230216N24Rik     Trbc2   Fam161b   Gm30948     Apbb1    Igfbp4  \\\n",
       "HSPC_025         3.915699  0.000000  1.189716  1.189716  0.000000  6.796659   \n",
       "HSPC_031         0.000000  0.000000  0.686872  8.533455  0.686872  7.664200   \n",
       "HSPC_037         0.000000  0.000000  7.535363  0.000000  0.000000  7.849521   \n",
       "LT-HSC_001       0.000000  2.364517  0.000000  2.364517  0.000000  3.217169   \n",
       "HSPC_001         0.377367  0.000000  0.000000  0.000000  0.000000  4.394439   \n",
       "\n",
       "              Pcp4l1    Rassf5    Cyp2r1  Smoc1       Srgn      Pygm  Gm43200  \\\n",
       "HSPC_025    7.695253  7.659135  0.000000    0.0   9.716627  7.320609      0.0   \n",
       "HSPC_031    8.304972  1.150286  0.000000    0.0  10.264835  0.000000      0.0   \n",
       "HSPC_037    2.657566  5.150271  5.303604    0.0  11.012021  0.000000      0.0   \n",
       "LT-HSC_001  3.217169  4.442877  2.364517    0.0  10.437787  8.483344      0.0   \n",
       "HSPC_001    0.000000  9.883934  0.000000    0.0  10.435905  0.000000      0.0   \n",
       "\n",
       "            Gca   Arhgef6       Fah  BC017643       Ak3     Icam1   Gm10505  \\\n",
       "HSPC_025    0.0  9.428233  0.000000  1.189716  6.983514  1.189716  0.000000   \n",
       "HSPC_031    0.0  9.858742  9.715412  8.730652  1.500480  6.462704  0.686872   \n",
       "HSPC_037    0.0  2.933024  0.000000  0.000000  9.275141  1.869807  0.000000   \n",
       "LT-HSC_001  0.0  4.909226  0.000000  3.749470  8.449492  0.000000  0.000000   \n",
       "HSPC_001    0.0  9.766528  0.377367  9.098330  6.086805  0.000000  0.000000   \n",
       "\n",
       "               C1qbp     Efna1   AW112010  Tnks1bp1     Anxa1     Fgf11  \\\n",
       "HSPC_025    8.536176  0.000000   8.156838       0.0  1.832751  0.000000   \n",
       "HSPC_031    4.595264  0.000000  10.762946       0.0  0.686872  0.000000   \n",
       "HSPC_037    7.644670  0.000000   8.289759       0.0  7.146761  0.000000   \n",
       "LT-HSC_001  8.124310  2.364517   4.694814       0.0  3.217169  6.766791   \n",
       "HSPC_001    8.816817  0.000000   7.525660       0.0  8.147335  0.377367   \n",
       "\n",
       "                Layn  Gm19331  Rbpms2    Tspan3  Ighv9-1   Gm43201     Arrdc1  \\\n",
       "HSPC_025    0.000000      0.0     0.0  7.535083      0.0  0.000000   7.515015   \n",
       "HSPC_031    0.000000      0.0     0.0  8.989663      0.0  0.686872   0.686872   \n",
       "HSPC_037    3.164226      0.0     0.0  8.331971      0.0  0.000000  10.386982   \n",
       "LT-HSC_001  7.941566      0.0     0.0  5.666688      0.0  0.000000   8.286489   \n",
       "HSPC_001    3.401495      0.0     0.0  6.237319      0.0  0.000000   1.134796   \n",
       "\n",
       "                Hjurp  4921507P07Rik       Sla    Ms4a6b  Zfp551  \\\n",
       "HSPC_025     8.274914        0.00000  4.242991  6.711045     0.0   \n",
       "HSPC_031     7.892380        0.00000  1.782055  2.697797     0.0   \n",
       "HSPC_037    10.113830        6.55335  2.657566  1.218731     0.0   \n",
       "LT-HSC_001   8.863498        0.00000  3.217169  2.364517     0.0   \n",
       "HSPC_001     1.482235        0.00000  8.566798  0.000000     0.0   \n",
       "\n",
       "            2810468N07Rik  Tnf     Serp1  Mfap2  Arhgef18  Slc25a29     Hmox1  \\\n",
       "HSPC_025              0.0  0.0  7.095865    0.0  0.000000       0.0  0.000000   \n",
       "HSPC_031              0.0  0.0  2.219938    0.0  2.697797       0.0  0.686872   \n",
       "HSPC_037              0.0  0.0  7.077557    0.0  4.916631       0.0  0.000000   \n",
       "LT-HSC_001            0.0  0.0  8.305537    0.0  3.749470       0.0  0.000000   \n",
       "HSPC_001              0.0  0.0  1.134796    0.0  9.515068       0.0  0.000000   \n",
       "\n",
       "                  Pkm  Arhgap15     Ddx39  Fv1  Gnb5       Tes    Lysmd2  \\\n",
       "HSPC_025     9.000423  7.712979  5.045572  0.0   0.0  7.871328  1.189716   \n",
       "HSPC_031     8.785511  6.830496  7.317821  0.0   0.0  7.659856  0.000000   \n",
       "HSPC_037    10.516827  8.050700  8.395907  0.0   0.0  6.707893  1.218731   \n",
       "LT-HSC_001  10.229170  4.137438  3.749470  0.0   0.0  8.187283  0.000000   \n",
       "HSPC_001     9.761568  8.943118  1.628905  0.0   0.0  9.188320  7.544266   \n",
       "\n",
       "            Mmp11    Pgrmc1  Gm42979     Efna4      Uba7       Xist     Sumo3  \\\n",
       "HSPC_025      0.0  8.774285      0.0  0.000000  8.256901   9.091325  9.254540   \n",
       "HSPC_031      0.0  2.219938      0.0  0.000000  2.219938   9.460858  3.342958   \n",
       "HSPC_037      0.0  8.107351      0.0  7.700976  8.515859  10.286297  8.546913   \n",
       "LT-HSC_001    0.0  7.674830      0.0  0.000000  9.055756   9.377142  7.787507   \n",
       "HSPC_001      0.0  0.676211      0.0  5.974679  8.515861   9.857676  9.503825   \n",
       "\n",
       "                 Flt3      Mycn  1300017J02Rik     Scn1b      Rab38  \\\n",
       "HSPC_025     7.054751  2.888576       1.832751  0.000000   7.399354   \n",
       "HSPC_031     8.124452  8.716082       0.000000  7.672848   1.500480   \n",
       "HSPC_037    10.304583  2.657566       0.000000  0.000000   2.933024   \n",
       "LT-HSC_001   3.217169  3.217169       0.000000  2.364517  10.104202   \n",
       "HSPC_001     3.882894  8.969171       0.000000  0.000000   1.134796   \n",
       "\n",
       "            ENSMUSG00000096970   Tnfaip2     Hdac2  Ccr7  Irf6     Mndal  \\\n",
       "HSPC_025                   0.0  0.000000  9.681046   0.0   0.0  8.570612   \n",
       "HSPC_031                   0.0  2.017546  8.830651   0.0   0.0  0.686872   \n",
       "HSPC_037                   0.0  2.933024  2.316800   0.0   0.0  8.760682   \n",
       "LT-HSC_001                 0.0  0.000000  9.078081   0.0   0.0  9.153609   \n",
       "HSPC_001                   0.0  0.676211  0.676211   0.0   0.0  5.082642   \n",
       "\n",
       "                Fut4     Casp1   Slc14a1      Rit1     Ifi203  Zfp93  \\\n",
       "HSPC_025    0.000000  6.418716  1.832751  1.189716   1.832751    0.0   \n",
       "HSPC_031    0.000000  8.568637  6.101957  0.000000  10.293858    0.0   \n",
       "HSPC_037    1.218731  7.906503  3.164226  1.869807   8.833854    0.0   \n",
       "LT-HSC_001  0.000000  3.749470  0.000000  0.000000   9.705823    0.0   \n",
       "HSPC_001    7.000696  0.000000  0.923649  0.676211   1.482235    0.0   \n",
       "\n",
       "               Calr3  2210010C04Rik   Gm38243   Gm43313   Slc25a5      Bcam  \\\n",
       "HSPC_025    0.000000            0.0  0.000000  0.000000  9.903830  1.189716   \n",
       "HSPC_031    0.686872            0.0  8.186162  0.000000  3.427154  0.000000   \n",
       "HSPC_037    0.000000            0.0  1.869807  1.218731  8.484121  0.000000   \n",
       "LT-HSC_001  0.000000            0.0  0.000000  0.000000  9.489678  0.000000   \n",
       "HSPC_001    0.000000            0.0  0.377367  0.000000  9.410571  0.000000   \n",
       "\n",
       "            Ighv1-74  Traf3ip3    Lgals9   Gm26982   Clec10a     Klhl8  Islr  \\\n",
       "HSPC_025    1.189716  1.189716  8.459496  0.000000  0.000000  1.832751   0.0   \n",
       "HSPC_031    0.000000  6.076110  4.075063  0.686872  0.686872  0.000000   0.0   \n",
       "HSPC_037    0.000000  9.076634  8.372984  0.000000  6.285223  0.000000   0.0   \n",
       "LT-HSC_001  0.000000  3.217169  9.066961  0.000000  0.000000  0.000000   0.0   \n",
       "HSPC_001    0.000000  8.086751  2.531943  0.000000  0.000000  0.000000   0.0   \n",
       "\n",
       "            Ighv1-76     Crlf3  Ighv1-77      Lcp2  Rapsn  Cd38   Gm37423  \\\n",
       "HSPC_025         0.0  1.832751  1.189716  5.935712    0.0   0.0  1.189716   \n",
       "HSPC_031         0.0  7.065378  0.000000  5.387358    0.0   0.0  0.000000   \n",
       "HSPC_037         0.0  8.484121  0.000000  1.218731    0.0   0.0  0.000000   \n",
       "LT-HSC_001       0.0  2.364517  0.000000  8.466517    0.0   0.0  0.000000   \n",
       "HSPC_001         0.0  8.571341  0.000000  0.377367    0.0   0.0  0.000000   \n",
       "\n",
       "              Selplg     Clip3  Ccdc157  Uggt2       Mpo      Eya1      Ctso  \\\n",
       "HSPC_025    2.275971  1.189716  0.00000    0.0  2.275971  0.000000  1.189716   \n",
       "HSPC_031    2.017546  0.000000  0.00000    0.0  2.697797  7.877493  5.672502   \n",
       "HSPC_037    3.363442  0.000000  0.00000    0.0  2.657566  0.000000  8.765091   \n",
       "LT-HSC_001  9.164084  0.000000  0.00000    0.0  3.217169  0.000000  4.694814   \n",
       "HSPC_001    0.676211  0.000000  6.38397    0.0  3.031264  5.004176  6.759286   \n",
       "\n",
       "              Gm26917      Rarb     Cmtm6  Metrnl       Rgs1     Ptpn6  \\\n",
       "HSPC_025     9.707812  0.000000  0.000000     0.0   8.786894  8.978607   \n",
       "HSPC_031    11.297833  0.686872  2.697797     0.0   1.500480  7.999391   \n",
       "HSPC_037    10.404042  0.000000  7.566005     0.0   3.694520  8.923351   \n",
       "LT-HSC_001   8.756821  0.000000  0.000000     0.0   3.749470  9.121723   \n",
       "HSPC_001    10.834868  0.000000  7.183903     0.0  10.077985  8.673117   \n",
       "\n",
       "               Cd1d1  Lyrm1    Prkaa2    Gm4759     Aplp2    Gm8995     Gng11  \\\n",
       "HSPC_025    8.691769    0.0  0.000000  9.785260  1.832751  8.967574  0.000000   \n",
       "HSPC_031    1.500480    0.0  0.686872  5.967830  2.827391  8.502254  0.686872   \n",
       "HSPC_037    7.545649    0.0  0.000000  5.986154  8.467986  4.190334  0.000000   \n",
       "LT-HSC_001  3.749470    0.0  0.000000  9.184806  8.595934  6.591640  7.271861   \n",
       "HSPC_001    8.596073    0.0  0.377367  0.676211  1.628905  1.628905  8.208397   \n",
       "\n",
       "            Tmem150b  Abhd6    Gm5111  Ankrd50    Neurl3   Slc44a2     Gm128  \\\n",
       "HSPC_025         0.0    0.0  6.983514   0.0000  6.779938  3.491677  0.000000   \n",
       "HSPC_031         0.0    0.0  8.161794   4.0219  8.753254  8.177073  0.686872   \n",
       "HSPC_037         0.0    0.0  6.553350   0.0000  8.301946  7.635068  7.394504   \n",
       "LT-HSC_001       0.0    0.0  0.000000   0.0000  6.591640  8.449492  0.000000   \n",
       "HSPC_001         0.0    0.0  0.000000   0.0000  0.923649  0.676211  0.000000   \n",
       "\n",
       "             Fam132a  2810414N06Rik      M6pr  Ankrd33b      Hexa  Pdcd1lg2  \\\n",
       "HSPC_025    2.614548            0.0  8.782703  0.000000  9.004027  0.000000   \n",
       "HSPC_031    3.722005            0.0  5.865923  8.880034  2.219938  0.000000   \n",
       "HSPC_037    7.348242            0.0  9.388059  0.000000  8.361384  1.218731   \n",
       "LT-HSC_001  3.217169            0.0  4.137438  0.000000  8.548753  0.000000   \n",
       "HSPC_001    4.787026            0.0  8.127421  0.377367  9.011572  7.007417   \n",
       "\n",
       "              Dnajc9       Lck     Ccnb2       Wls   Gramd1a   Gm37642  \\\n",
       "HSPC_025    4.802330  4.734524  3.491677  1.189716  7.320609  0.000000   \n",
       "HSPC_031    2.397399  0.000000  1.500480  7.005018  9.698571  0.686872   \n",
       "HSPC_037    7.682451  8.641061  1.869807  8.636256  9.756806  6.309572   \n",
       "LT-HSC_001  3.217169  0.000000  0.000000  2.364517  9.789383  0.000000   \n",
       "HSPC_001    1.482235  0.676211  0.377367  0.000000  0.377367  0.377367   \n",
       "\n",
       "             St8sia4  Igkv12-44    Sqstm1  Slc25a35     Tipin  4930555A03Rik  \\\n",
       "HSPC_025    9.299230        0.0  9.501458  1.189716  8.555954       0.000000   \n",
       "HSPC_031    1.150286        0.0  9.231299  0.000000  5.449074       6.492322   \n",
       "HSPC_037    9.612592        0.0  9.883858  1.218731  7.615671       2.657566   \n",
       "LT-HSC_001  4.137438        0.0  6.591640  8.641622  4.137438       0.000000   \n",
       "HSPC_001    0.676211        0.0  1.482235  0.377367  8.144289       6.763263   \n",
       "\n",
       "            Rn18s-rs5    Samd12  B9d1      Ncf4        Myc  Uaca       Irf9  \\\n",
       "HSPC_025    15.299863  0.000000   0.0  1.832751   9.365173   0.0   6.106372   \n",
       "HSPC_031    14.849717  0.686872   0.0  0.000000   2.697797   0.0   1.500480   \n",
       "HSPC_037    15.812094  0.000000   0.0  6.074055  10.234780   0.0   7.359948   \n",
       "LT-HSC_001  15.593200  0.000000   0.0  7.063866   9.421470   0.0  10.020216   \n",
       "HSPC_001    14.466537  0.000000   0.0  0.377367   6.021909   0.0   0.676211   \n",
       "\n",
       "               Paics     Gstm1     Padi4     Tor3a     Rgs18  Slc26a6  \\\n",
       "HSPC_025    9.656065  8.176136  6.258964  2.275971  9.118180      0.0   \n",
       "HSPC_031    3.722005  8.149453  8.417314  0.686872  8.817061      0.0   \n",
       "HSPC_037    8.271282  7.312546  1.869807  0.000000  9.998750      0.0   \n",
       "LT-HSC_001  5.261087  7.674830  0.000000  0.000000  7.760152      0.0   \n",
       "HSPC_001    8.618195  9.168968  8.661447  0.000000  8.059525      0.0   \n",
       "\n",
       "               Ppm1g    Zfand5     Smpd5  Hdac9      Gnl3  Ecm1    Rnase6  \\\n",
       "HSPC_025    3.491677  9.901899  0.000000    0.0  9.362368   0.0  1.189716   \n",
       "HSPC_031    7.209055  8.634314  0.686872    0.0  5.925034   0.0  0.686872   \n",
       "HSPC_037    7.857800  9.885883  0.000000    0.0  8.808450   0.0  2.316800   \n",
       "LT-HSC_001  3.217169  7.584142  0.000000    0.0  5.885018   0.0  0.000000   \n",
       "HSPC_001    1.996276  1.996276  0.000000    0.0  8.620389   0.0  0.000000   \n",
       "\n",
       "            Lgals3bp   Slc2a10     Rdh14  Icos     Dnah1  Amt      Fut8  \\\n",
       "HSPC_025    7.764886  0.000000  1.189716   0.0  0.000000  0.0  5.392129   \n",
       "HSPC_031    8.972252  0.000000  7.839589   0.0  0.000000  0.0  8.354193   \n",
       "HSPC_037    7.898499  0.000000  0.000000   0.0  0.000000  0.0  1.869807   \n",
       "LT-HSC_001  8.548753  2.364517  2.364517   0.0  7.107933  0.0  7.018409   \n",
       "HSPC_001    9.508570  0.000000  1.482235   0.0  0.000000  0.0  1.134796   \n",
       "\n",
       "               Itpkc     Ap1s2  Rgs11    Hpcal1   Gm43178  Rnase4     Adgrl4  \\\n",
       "HSPC_025    2.275971  0.000000    0.0  0.000000  0.000000     0.0   8.226370   \n",
       "HSPC_031    0.000000  0.000000    0.0  3.158217  0.686872     0.0   9.163881   \n",
       "HSPC_037    1.218731  2.657566    0.0  0.000000  0.000000     0.0  10.679799   \n",
       "LT-HSC_001  0.000000  0.000000    0.0  4.137438  0.000000     0.0   8.035830   \n",
       "HSPC_001    0.000000  0.000000    0.0  7.676647  0.000000     0.0   8.396780   \n",
       "\n",
       "                Nek6      Clk1      Eya2     Csf3r  Fkbp1b      Pirb  \\\n",
       "HSPC_025    0.000000  9.475731  2.275971  1.832751     0.0  1.189716   \n",
       "HSPC_031    5.084431  9.607904  0.686872  8.894896     0.0  0.686872   \n",
       "HSPC_037    0.000000  9.476740  2.316800  4.291594     0.0  0.000000   \n",
       "LT-HSC_001  3.749470  4.694814  6.710738  0.000000     0.0  8.499976   \n",
       "HSPC_001    0.000000  2.100526  9.437569  0.676211     0.0  0.000000   \n",
       "\n",
       "               Msmo1   Gm15133      Pim2  Cldn15  Gm28557     Ric8a  Triqk  \\\n",
       "HSPC_025    1.832751  3.491677  1.189716     0.0      0.0  7.148920    0.0   \n",
       "HSPC_031    0.000000  0.000000  0.686872     0.0      0.0  1.500480    0.0   \n",
       "HSPC_037    1.218731  0.000000  1.218731     0.0      0.0  9.889926    0.0   \n",
       "LT-HSC_001  9.447428  5.666688  0.000000     0.0      0.0  9.594069    0.0   \n",
       "HSPC_001    0.000000  0.000000  8.639983     0.0      0.0  9.758583    0.0   \n",
       "\n",
       "               Spns2  Cebpe   Tspan14     Itm2a      Ddx1  Sh3tc1  Slc22a18  \\\n",
       "HSPC_025    1.832751    0.0  9.018355  0.000000  8.280868     0.0  0.000000   \n",
       "HSPC_031    0.000000    0.0  6.861088  0.000000  9.492957     0.0  8.775508   \n",
       "HSPC_037    1.218731    0.0  8.233604  0.000000  8.384491     0.0  0.000000   \n",
       "LT-HSC_001  8.483344    0.0  9.340672  2.364517  0.000000     0.0  3.217169   \n",
       "HSPC_001    5.600985    0.0  9.989108  0.000000  1.318950     0.0  0.000000   \n",
       "\n",
       "                 Lcp1     Casp2    Epsti1     Ifi44    Phf11b      Ctsb  \\\n",
       "HSPC_025     9.322510  8.536176  0.000000  8.722721  7.756364  9.457444   \n",
       "HSPC_031     9.517171  0.000000  7.928939  2.397399  0.000000  3.056145   \n",
       "HSPC_037    10.199386  7.824394  1.869807  5.038175  0.000000  6.896517   \n",
       "LT-HSC_001  10.219159  0.000000  3.217169  9.078081  0.000000  9.887456   \n",
       "HSPC_001     9.627852  0.676211  7.553480  0.000000  0.000000  7.478070   \n",
       "\n",
       "                H2afy      Ctsg    Gimap9    Hsd3b7   Smpdl3a   Gm43162  \\\n",
       "HSPC_025     9.874597  0.000000  1.189716  1.832751  1.189716  6.763021   \n",
       "HSPC_031    11.210691  0.686872  9.372041  6.511734  9.587467  0.000000   \n",
       "HSPC_037    11.337700  0.000000  1.218731  2.933024  1.218731  0.000000   \n",
       "LT-HSC_001   8.342895  2.364517  8.876294  2.364517  9.368110  0.000000   \n",
       "HSPC_001     9.471989  1.628905  0.377367  8.708603  0.676211  0.000000   \n",
       "\n",
       "              Trim47      Cpa3       Cat     Cers2     Ifit3  Ifit1bl1  \\\n",
       "HSPC_025    0.000000  1.189716  3.317239  8.887885  1.189716  1.189716   \n",
       "HSPC_031    9.053970  1.500480  9.685810  5.184588  0.000000  0.000000   \n",
       "HSPC_037    1.218731  0.000000  8.867044  9.933662  8.367196  5.527704   \n",
       "LT-HSC_001  0.000000  0.000000  5.666688  5.982925  2.364517  5.095857   \n",
       "HSPC_001    0.000000  0.377367  8.396780  8.817774  0.377367  0.000000   \n",
       "\n",
       "            Slc9a3r2      Mcm3    Fscn1  Thbd      Cd93     Sept6      Irf5  \\\n",
       "HSPC_025    1.832751  8.922578  0.00000   0.0  2.275971  2.888576  0.000000   \n",
       "HSPC_031    0.000000  9.000010  0.00000   0.0  4.700515  8.140128  0.000000   \n",
       "HSPC_037    0.000000  7.359948  0.00000   0.0  8.246273  9.231205  1.218731   \n",
       "LT-HSC_001  0.000000  5.261087  0.00000   0.0  4.442877  3.217169  0.000000   \n",
       "HSPC_001    0.000000  1.883902  4.83315   0.0  0.000000  8.618195  0.000000   \n",
       "\n",
       "               Rab19      Ctsz  Rhbdf1      Wfs1     Mef2c     Blvrb  \\\n",
       "HSPC_025    1.189716  9.454813     0.0  6.542841  8.117451  1.832751   \n",
       "HSPC_031    1.500480  8.654102     0.0  0.000000  9.431856  3.909308   \n",
       "HSPC_037    0.000000  8.557117     0.0  0.000000  7.048918  3.963623   \n",
       "LT-HSC_001  0.000000  3.217169     0.0  0.000000  3.217169  3.217169   \n",
       "HSPC_001    0.000000  1.762030     0.0  0.000000  2.977514  3.031264   \n",
       "\n",
       "               Gimap1  Gimap7  Gimap4  4930515G01Rik     Hgfac     Gimap6  \\\n",
       "HSPC_025     8.378509     0.0     0.0            0.0  0.000000   8.627797   \n",
       "HSPC_031     3.506705     0.0     0.0            0.0  5.655149   8.634314   \n",
       "HSPC_037     6.129815     0.0     0.0            0.0  0.000000   9.427529   \n",
       "LT-HSC_001  10.082279     0.0     0.0            0.0  0.000000   7.760152   \n",
       "HSPC_001     8.331331     0.0     0.0            0.0  0.000000  10.336666   \n",
       "\n",
       "             Gm15201    Gimap5  BC035044       Ly6e  Hs3st1     Zfp62  \\\n",
       "HSPC_025    1.189716  1.189716  2.275971  11.533395     0.0  5.842161   \n",
       "HSPC_031    1.500480  6.861088  9.823251  10.901846     0.0  0.000000   \n",
       "HSPC_037    0.000000  7.857800  8.655380  10.146300     0.0  0.000000   \n",
       "LT-HSC_001  0.000000  7.232592  3.749470  11.172608     0.0  0.000000   \n",
       "HSPC_001    0.000000  0.377367  1.134796   9.692875     0.0  5.069857   \n",
       "\n",
       "              Vpreb3  Kcnh2      Hn1l        Hlf  9930012K11Rik  Sgsm1  \\\n",
       "HSPC_025    0.000000    0.0  4.663373   7.814991            0.0    0.0   \n",
       "HSPC_031    0.000000    0.0  1.782055   9.126594            0.0    0.0   \n",
       "HSPC_037    0.000000    0.0  6.235258  10.552968            0.0    0.0   \n",
       "LT-HSC_001  3.217169    0.0  6.591640   7.419049            0.0    0.0   \n",
       "HSPC_001    0.000000    0.0  1.482235   8.778042            0.0    0.0   \n",
       "\n",
       "                Gmpr    Lancl1   Slc16a1     Plcb2      Sdpr      Rhoh  \\\n",
       "HSPC_025    1.189716  1.189716  8.256901  8.333382  1.189716  9.164007   \n",
       "HSPC_031    0.000000  8.728580  2.219938  4.595264  0.000000  9.771850   \n",
       "HSPC_037    1.218731  0.000000  1.218731  8.014129  0.000000  4.783895   \n",
       "LT-HSC_001  8.267186  2.364517  0.000000  8.166596  0.000000  3.217169   \n",
       "HSPC_001    0.000000  0.923649  3.853357  8.359182  0.000000  8.839592   \n",
       "\n",
       "            Gm38250  Gm26532      Dock2    Pdlim2      Clk4     Nubp2  \\\n",
       "HSPC_025        0.0      0.0   7.721761  6.418716  7.879200  7.535083   \n",
       "HSPC_031        0.0      0.0   8.789493  0.000000  1.782055  9.018787   \n",
       "HSPC_037        0.0      0.0   6.943952  6.726097  2.933024  4.291594   \n",
       "LT-HSC_001      0.0      0.0  10.115040  7.732268  4.442877  4.694814   \n",
       "HSPC_001        0.0      0.0   0.923649  0.000000  4.690105  8.598301   \n",
       "\n",
       "              Treml2      Sell      Polm   Pglyrp2  Gm37829   Tsc22d1  \\\n",
       "HSPC_025    6.877476  0.000000  0.000000  6.968835      0.0  9.384659   \n",
       "HSPC_031    3.787179  8.822902  0.000000  5.322884      0.0  2.397399   \n",
       "HSPC_037    0.000000  3.164226  0.000000  8.582317      0.0  9.529518   \n",
       "LT-HSC_001  8.124310  4.137438  0.000000  7.584142      0.0  8.714692   \n",
       "HSPC_001    0.000000  1.318950  0.377367  7.408690      0.0  8.307024   \n",
       "\n",
       "            9130008F23Rik  Gm37558  Gm37706    Ptprcap       Hck  Adamts10  \\\n",
       "HSPC_025         0.000000      0.0      0.0   9.351091  0.000000  3.118771   \n",
       "HSPC_031         1.150286      0.0      0.0  10.055096  0.686872  0.000000   \n",
       "HSPC_037         0.000000      0.0      0.0   9.828064  1.218731  8.214389   \n",
       "LT-HSC_001       0.000000      0.0      0.0   9.912520  0.000000  5.095857   \n",
       "HSPC_001         0.000000      0.0      0.0  11.226616  0.000000  0.377367   \n",
       "\n",
       "                 Ly6a  Gm37598      Anxa5     Parvg  Acer2     Cd79a  \\\n",
       "HSPC_025     9.428233      0.0   7.545014  8.872193    0.0  0.000000   \n",
       "HSPC_031     8.612002      0.0   3.056145  8.751214    0.0  0.000000   \n",
       "HSPC_037     3.363442      0.0   2.316800  9.215184    0.0  0.000000   \n",
       "LT-HSC_001  10.283019      0.0  10.093283  4.442877    0.0  4.909226   \n",
       "HSPC_001     8.840533      0.0   8.171473  8.984579    0.0  0.000000   \n",
       "\n",
       "             Tmem175  Fcrl1  Dusp22    Ms4a4c     Bank1  Gm43149    Gatsl3  \\\n",
       "HSPC_025    6.693295    0.0     0.0  0.000000  1.189716      0.0  0.000000   \n",
       "HSPC_031    9.337102    0.0     0.0  0.000000  0.000000      0.0  0.000000   \n",
       "HSPC_037    1.218731    0.0     0.0  0.000000  0.000000      0.0  0.000000   \n",
       "LT-HSC_001  0.000000    0.0     0.0  2.364517  5.095857      0.0  2.364517   \n",
       "HSPC_001    0.000000    0.0     0.0  0.000000  5.953955      0.0  0.000000   \n",
       "\n",
       "            BC026585     Wfdc2     Camk1  Dgkq    Treml1      Ebi3  Gm27252  \\\n",
       "HSPC_025    2.275971  0.000000  9.124817   0.0  1.832751  6.581951      0.0   \n",
       "HSPC_031    6.807118  0.000000  8.318813   0.0  0.000000  1.150286      0.0   \n",
       "HSPC_037    1.218731  0.000000  1.869807   0.0  0.000000  6.912502      0.0   \n",
       "LT-HSC_001  4.694814  0.000000  3.217169   0.0  0.000000  8.466517      0.0   \n",
       "HSPC_001    0.000000  7.377903  0.923649   0.0  0.000000  7.458585      0.0   \n",
       "\n",
       "              Magee1  Sdc2      Ldhb  Kmo    Bpifb5   Trim30a     Ifitm1  \\\n",
       "HSPC_025    0.000000   0.0  8.464736  0.0  1.832751  8.744431  11.084242   \n",
       "HSPC_031    1.150286   0.0  0.686872  0.0  1.150286  7.925325  11.145000   \n",
       "HSPC_037    0.000000   0.0  2.316800  0.0  1.869807  3.363442   9.865499   \n",
       "LT-HSC_001  0.000000   0.0  8.207678  0.0  0.000000  4.442877  11.771131   \n",
       "HSPC_001    0.000000   0.0  8.116584  0.0  8.717852  9.644115  11.752090   \n",
       "\n",
       "               Ddx58     Ifitm3    Rmnd5b  Gm26772  Gm16151  Gm16150  \\\n",
       "HSPC_025    1.189716  10.748367  7.525084      0.0      0.0      0.0   \n",
       "HSPC_031    0.686872  10.561133  8.130743      0.0      0.0      0.0   \n",
       "HSPC_037    5.859945  10.011792  8.181786      0.0      0.0      0.0   \n",
       "LT-HSC_001  8.012835  10.802043  9.089116      0.0      0.0      0.0   \n",
       "HSPC_001    0.000000  10.211298  9.051950      0.0      0.0      0.0   \n",
       "\n",
       "               Tagln2  3110083C13Rik  Cyp39a1    Tspyl3   Dennd1c    Slc2a1  \\\n",
       "HSPC_025     9.263590            0.0      0.0  1.832751  8.832203  7.012433   \n",
       "HSPC_031     9.722719            0.0      0.0  2.946297  8.765435  0.000000   \n",
       "HSPC_037     9.476740            0.0      0.0  7.225650  7.186745  1.218731   \n",
       "LT-HSC_001  11.133169            0.0      0.0  2.364517  6.461820  3.217169   \n",
       "HSPC_001     9.945156            0.0      0.0  9.002350  9.150871  2.531943   \n",
       "\n",
       "              Large1  AB124611  Gm17096     Stxbp4     Muc3a     Awat2  \\\n",
       "HSPC_025    1.832751       0.0      0.0  10.351401  0.000000  0.000000   \n",
       "HSPC_031    0.000000       0.0      0.0   1.150286  7.267321  0.000000   \n",
       "HSPC_037    1.218731       0.0      0.0   0.000000  0.000000  1.869807   \n",
       "LT-HSC_001  0.000000       0.0      0.0   9.554808  2.364517  0.000000   \n",
       "HSPC_001    0.377367       0.0      0.0   0.377367  0.377367  0.000000   \n",
       "\n",
       "               Plac8  AI506816      Canx  Alox5     Prdx6      F11r      Alg2  \\\n",
       "HSPC_025    8.021134  2.275971  9.658353    0.0  9.000423  1.189716  0.000000   \n",
       "HSPC_031    9.810572  2.219938  9.793820    0.0  9.333015  4.700515  5.184588   \n",
       "HSPC_037    8.462568  3.538458  7.300448    0.0  9.935619  0.000000  1.869807   \n",
       "LT-HSC_001  4.442877  3.217169  5.543737    0.0  5.666688  6.591640  2.364517   \n",
       "HSPC_001    2.921687  7.820968  9.959956    0.0  9.118646  0.377367  8.493298   \n",
       "\n",
       "              Lurap1  Ttc30b    Inpp5k  Dcdc2b  Tnfsf4   Atp6ap1      Dapp1  \\\n",
       "HSPC_025    0.000000     0.0  3.118771     0.0     0.0  8.531189   8.753024   \n",
       "HSPC_031    0.000000     0.0  1.500480     0.0     0.0  1.782055   7.788776   \n",
       "HSPC_037    5.859945     0.0  3.538458     0.0     0.0  8.494778  10.042988   \n",
       "LT-HSC_001  0.000000     0.0  8.656534     0.0     0.0  3.217169   9.554808   \n",
       "HSPC_001    0.000000     0.0  0.923649     0.0     0.0  1.628905   2.197748   \n",
       "\n",
       "            1500002C15Rik    Tuba4a  Gm43254  ENSMUSG00000029333      Gclm  \\\n",
       "HSPC_025              0.0  7.421084      0.0                 0.0  3.118771   \n",
       "HSPC_031              0.0  3.342958      0.0                 0.0  3.253543   \n",
       "HSPC_037              0.0  4.475001      0.0                 0.0  3.363442   \n",
       "LT-HSC_001            0.0  8.532677      0.0                 0.0  2.364517   \n",
       "HSPC_001              0.0  9.216145      0.0                 0.0  3.519027   \n",
       "\n",
       "              Ruvbl2     Apobr  Nap1l3     Cct6a       Vav1      Rfc2  \\\n",
       "HSPC_025    8.367359  5.347433     0.0  9.160781   2.614548  8.327641   \n",
       "HSPC_031    6.807118  0.000000     0.0  7.537344   8.820957  8.288184   \n",
       "HSPC_037    8.355550  0.000000     0.0  3.538458   8.557117  4.978682   \n",
       "LT-HSC_001  6.710738  0.000000     0.0  2.364517   7.840709  3.217169   \n",
       "HSPC_001    1.134796  0.000000     0.0  6.167028  10.550200  7.941667   \n",
       "\n",
       "            Gm16001  Atp1b1  Gm19708     Nradd     Ypel3     Tor4a   Gm19590  \\\n",
       "HSPC_025        0.0     0.0      0.0  4.033241  6.693295  7.187470  9.514152   \n",
       "HSPC_031        0.0     0.0      0.0  0.000000  7.129612  0.686872  6.640763   \n",
       "HSPC_037        0.0     0.0      0.0  0.000000  8.121174  1.218731  8.587306   \n",
       "LT-HSC_001      0.0     0.0      0.0  0.000000  8.611324  5.409323  6.710738   \n",
       "HSPC_001        0.0     0.0      0.0  0.000000  5.537397  0.000000  0.676211   \n",
       "\n",
       "             Ivns1abp  Gm15991  Upp1  Gm6157  Eif5a2   C1qtnf6  4933424M12Rik  \\\n",
       "HSPC_025     8.213975      0.0   0.0     0.0     0.0  6.209872       0.000000   \n",
       "HSPC_031     6.472644      0.0   0.0     0.0     0.0  0.000000       0.000000   \n",
       "HSPC_037     9.111674      0.0   0.0     0.0     0.0  6.553350       0.000000   \n",
       "LT-HSC_001  10.509359      0.0   0.0     0.0     0.0  4.442877       3.217169   \n",
       "HSPC_001     8.250077      0.0   0.0     0.0     0.0  0.377367       0.000000   \n",
       "\n",
       "              Mageh1   Gm11696      Cbfb    Zfp422      Mfng      Klf8  \\\n",
       "HSPC_025    3.317239  0.000000  2.614548  7.122636  9.491221  1.189716   \n",
       "HSPC_031    0.000000  0.000000  3.582099  2.017546  8.043406  0.000000   \n",
       "HSPC_037    0.000000  6.813823  7.914462  8.175175  7.930251  0.000000   \n",
       "LT-HSC_001  0.000000  0.000000  5.261087  0.000000  8.714692  0.000000   \n",
       "HSPC_001    0.000000  0.000000  1.482235  0.377367  9.303379  0.000000   \n",
       "\n",
       "              Stk17b  Met  Ufsp1  Tmem150a  AI606181     Ikzf2    Slc34a2  \\\n",
       "HSPC_025    1.189716  0.0    0.0       0.0  0.000000  8.169733  11.876887   \n",
       "HSPC_031    0.000000  0.0    0.0       0.0  1.150286  7.261599  11.510276   \n",
       "HSPC_037    1.869807  0.0    0.0       0.0  0.000000  8.812716  12.473957   \n",
       "LT-HSC_001  0.000000  0.0    0.0       0.0  0.000000  8.342895  12.910433   \n",
       "HSPC_001    0.377367  0.0    0.0       0.0  0.000000  4.604046  10.497768   \n",
       "\n",
       "            1700066B19Rik      Mcm7  Fbxo48     Ecscr   Lyplal1   Ankrd37  \\\n",
       "HSPC_025         0.000000  8.316089     0.0  0.000000  0.000000  0.000000   \n",
       "HSPC_031         0.686872  2.555402     0.0  0.000000  0.000000  0.000000   \n",
       "HSPC_037         0.000000  5.757471     0.0  0.000000  1.218731  0.000000   \n",
       "LT-HSC_001       0.000000  4.442877     0.0  7.107933  0.000000  2.364517   \n",
       "HSPC_001         0.000000  2.531943     0.0  0.000000  0.000000  0.000000   \n",
       "\n",
       "                Plek  Mapkbp1   Ppp1r3d   Exoc3l2    Tmem53      Wsb1  \\\n",
       "HSPC_025    2.888576      0.0  0.000000  1.189716  6.184685  1.189716   \n",
       "HSPC_031    0.686872      0.0  0.000000  7.655500  0.000000  4.075063   \n",
       "HSPC_037    9.293568      0.0  0.000000  5.351295  0.000000  6.796699   \n",
       "LT-HSC_001  2.364517      0.0  2.364517  0.000000  0.000000  2.364517   \n",
       "HSPC_001    0.000000      0.0  0.000000  0.000000  0.000000  5.867946   \n",
       "\n",
       "                Rtkn      Tfr2    Leprot  Arhgap25  Nupr1     Plpp7  \\\n",
       "HSPC_025    5.558232  2.614548  7.082290  8.083785    0.0  0.000000   \n",
       "HSPC_031    0.000000  9.710171  1.782055  7.877493    0.0  0.000000   \n",
       "HSPC_037    0.000000  2.933024  8.451670  1.869807    0.0  1.218731   \n",
       "LT-HSC_001  0.000000  0.000000  3.217169  8.811145    0.0  0.000000   \n",
       "HSPC_001    0.000000  0.923649  1.762030  4.099659    0.0  0.000000   \n",
       "\n",
       "            G730003C15Rik      Rsrp1     Samsn1     Prdx3   Gm37663     Itgb3  \\\n",
       "HSPC_025              0.0   8.989556   9.202161  3.317239  0.000000  0.000000   \n",
       "HSPC_031              0.0   9.001726   9.143804  6.009394  0.000000  1.150286   \n",
       "HSPC_037              0.0  11.369171  10.099937  7.186745  1.218731  0.000000   \n",
       "LT-HSC_001            0.0  10.120428   6.710738  7.732268  0.000000  0.000000   \n",
       "HSPC_001              0.0  10.043252   1.134796  1.762030  0.000000  0.000000   \n",
       "\n",
       "            Rtn4r      Nrros   Dennd2d        Por  Tspear  Hsd17b12    Capza2  \\\n",
       "HSPC_025      0.0   8.832203  1.189716   8.459496     0.0  7.695253  9.989955   \n",
       "HSPC_031      0.0  10.457334  0.686872   8.482714     0.0  7.220899  5.850759   \n",
       "HSPC_037      0.0   8.283626  0.000000   9.237565     0.0  2.316800  4.081427   \n",
       "LT-HSC_001    0.0   4.694814  0.000000  10.788568     0.0  8.742914  6.971475   \n",
       "HSPC_001      0.0   0.377367  0.000000   7.636025     0.0  1.134796  9.846475   \n",
       "\n",
       "            Osgin1     Spns3       Cd34  4921531C22Rik    Trmt2a   Gm26692  \\\n",
       "HSPC_025       0.0  0.000000  10.686910       0.000000  2.275971  1.189716   \n",
       "HSPC_031       0.0  0.000000   9.467087       7.350532  1.782055  0.000000   \n",
       "HSPC_037       0.0  0.000000  10.726889       7.336441  7.728326  0.000000   \n",
       "LT-HSC_001     0.0  2.364517   4.909226       0.000000  9.768942  0.000000   \n",
       "HSPC_001       0.0  0.676211   9.338449       0.000000  0.377367  0.377367   \n",
       "\n",
       "             Col16a1  Cd46  Ptgds    Uqcrc1  Gm28512     Hacd4  Ttc39c  \\\n",
       "HSPC_025    0.000000   0.0    0.0  7.068586      0.0  7.739166     0.0   \n",
       "HSPC_031    3.158217   0.0    0.0  8.994845      0.0  8.934992     0.0   \n",
       "HSPC_037    0.000000   0.0    0.0  3.835337      0.0  6.880354     0.0   \n",
       "LT-HSC_001  0.000000   0.0    0.0  6.820749      0.0  0.000000     0.0   \n",
       "HSPC_001    0.000000   0.0    0.0  9.600889      0.0  8.113473     0.0   \n",
       "\n",
       "            Igkv1-135   Fam129c      Rhof      Sdcbp     Rcsd1     Mmrn1  \\\n",
       "HSPC_025          0.0  1.189716  0.000000   9.892208  7.970453  1.189716   \n",
       "HSPC_031          0.0  0.000000  0.686872   6.511734  2.219938  0.686872   \n",
       "HSPC_037          0.0  0.000000  0.000000   7.781518  3.164226  1.218731   \n",
       "LT-HSC_001        0.0  0.000000  6.319152   9.340672  8.626553  4.137438   \n",
       "HSPC_001          0.0  0.000000  0.377367  10.449541  2.673882  9.999258   \n",
       "\n",
       "            Ccser1  Ccdc92b  Tnfaip8l1     Tprgl       Gem  D630039A03Rik  \\\n",
       "HSPC_025       0.0      0.0        0.0  7.484379  9.141275            0.0   \n",
       "HSPC_031       0.0      0.0        0.0  0.686872  0.686872            0.0   \n",
       "HSPC_037       0.0      0.0        0.0  4.475001  8.473385            0.0   \n",
       "LT-HSC_001     0.0      0.0        0.0  8.124310  8.247621            0.0   \n",
       "HSPC_001       0.0      0.0        0.0  0.676211  0.000000            0.0   \n",
       "\n",
       "            Lrrc36  Map10   Gm38071     Ccng2       Ldha     Ramp1       Ucp2  \\\n",
       "HSPC_025       0.0    0.0  0.000000  2.275971   8.511066  8.244766  10.309781   \n",
       "HSPC_031       0.0    0.0  0.000000  0.000000  10.249019  9.670777   9.728952   \n",
       "HSPC_037       0.0    0.0  2.933024  7.737329   8.289759  9.379458   9.663070   \n",
       "LT-HSC_001     0.0    0.0  0.000000  0.000000  10.002816  8.926375   5.982925   \n",
       "HSPC_001       0.0    0.0  0.377367  0.000000  10.079579  9.070521  10.222171   \n",
       "\n",
       "                Sdsl      Ttc4   Afap1l1      Ccnd2  Sult1a1    Ube2l6  \\\n",
       "HSPC_025    0.000000  7.068586  5.518464   7.332125      0.0  8.832203   \n",
       "HSPC_031    2.555402  1.500480  9.080214   6.807118      0.0  8.846027   \n",
       "HSPC_037    1.869807  8.424058  7.719267   8.981337      0.0  9.076634   \n",
       "LT-HSC_001  0.000000  3.749470  3.749470   9.669524      0.0  5.982925   \n",
       "HSPC_001    8.300199  0.676211  8.450785  10.698247      0.0  7.622956   \n",
       "\n",
       "             Clec12a   Gm43643  Smtnl1      Aqp1  Large2     Creg1  Fam221a  \\\n",
       "HSPC_025    1.189716  5.965594     0.0  3.118771     0.0  8.384051      0.0   \n",
       "HSPC_031    0.000000  0.000000     0.0  2.397399     0.0  5.278242      0.0   \n",
       "HSPC_037    1.218731  6.333516     0.0  2.657566     0.0  3.694520      0.0   \n",
       "LT-HSC_001  0.000000  0.000000     0.0  0.000000     0.0  8.397178      0.0   \n",
       "HSPC_001    0.923649  0.000000     0.0  0.676211     0.0  8.228669      0.0   \n",
       "\n",
       "               Muc13  Slc25a11  Grap      Ncf1   B4galt4   Gm16758     Nucb1  \\\n",
       "HSPC_025    2.275971  8.238660   0.0  4.588530  1.189716  0.000000  8.411450   \n",
       "HSPC_031    2.397399  7.429204   0.0  7.740229  0.686872  0.000000  2.219938   \n",
       "HSPC_037    4.190334  9.094260   0.0  8.141662  0.000000  0.000000  8.155161   \n",
       "LT-HSC_001  4.137438  7.383635   0.0  0.000000  5.409323  0.000000  9.293747   \n",
       "HSPC_001    8.283684  9.610853   0.0  0.000000  0.000000  2.604657  9.476233   \n",
       "\n",
       "              Fam69b   Tmem35b       Mx1   Ppp1r26       Mx2   Ppp1r15a  \\\n",
       "HSPC_025    6.877476  7.421084  1.832751  6.258964  0.000000   5.842161   \n",
       "HSPC_031    9.839666  8.596177  0.000000  0.000000  0.000000   0.000000   \n",
       "HSPC_037    8.114280  7.790196  4.712649  0.000000  0.000000   1.218731   \n",
       "LT-HSC_001  8.626553  6.160812  0.000000  0.000000  4.694814  10.805393   \n",
       "HSPC_001    6.599451  0.923649  0.000000  0.000000  0.000000   0.000000   \n",
       "\n",
       "            Pdzk1ip1     Coro1a     Mob3c      Oas2   Kctd12b  Mefv   Gm12250  \\\n",
       "HSPC_025    0.000000  11.228325  1.189716  5.253659  1.189716   0.0  6.923879   \n",
       "HSPC_031    0.000000   9.762764  1.150286  0.686872  0.000000   0.0  0.686872   \n",
       "HSPC_037    1.218731   9.991242  1.869807  2.933024  8.378749   0.0  9.149260   \n",
       "LT-HSC_001  6.528191   8.247621  9.205236  0.000000  3.217169   0.0  8.756821   \n",
       "HSPC_001    8.156434   9.612506  0.377367  0.000000  0.000000   0.0  7.873411   \n",
       "\n",
       "               Sh2d5      Igtp     Ermap      Smu1   Maged2      Mcm4  \\\n",
       "HSPC_025    0.000000  1.832751  1.832751  3.118771  0.00000  9.157549   \n",
       "HSPC_031    0.000000  0.000000  1.782055  9.107582  0.00000  2.697797   \n",
       "HSPC_037    6.129815  1.218731  3.363442  8.181786  0.00000  5.150271   \n",
       "LT-HSC_001  0.000000  9.143059  2.364517  7.347332  0.00000  6.319152   \n",
       "HSPC_001    0.000000  0.000000  1.628905  6.414630  5.52808  8.885003   \n",
       "\n",
       "             Gm42576      Anxa6  1700123M08Rik      Rtp4   Sh3bgrl     Napsa  \\\n",
       "HSPC_025    0.000000   0.000000            0.0  8.433001  7.442493  7.261610   \n",
       "HSPC_031    0.686872  10.531721            0.0  1.782055  1.150286  5.255393   \n",
       "HSPC_037    0.000000   1.869807            0.0  8.577312  8.331971  7.439328   \n",
       "LT-HSC_001  0.000000   5.409323            0.0  9.768942  3.217169  3.217169   \n",
       "HSPC_001    0.676211   0.676211            0.0  7.242044  1.318950  2.921687   \n",
       "\n",
       "              Kctd21      Chpf    Gm7160   Neurl1b       Cct3    Nkx2-3  \\\n",
       "HSPC_025    0.000000  7.704143  0.000000  0.000000   9.588054  1.189716   \n",
       "HSPC_031    0.686872  0.686872  0.000000  0.000000   3.506705  4.919811   \n",
       "HSPC_037    0.000000  0.000000  7.394504  0.000000   9.379458  8.510617   \n",
       "LT-HSC_001  7.645229  2.364517  2.364517  0.000000   7.383635  6.319152   \n",
       "HSPC_001    0.000000  0.377367  0.000000  0.377367  10.542702  8.477653   \n",
       "\n",
       "               Wdr78      Dusp1      Def8       Rbm5  BC016579       Emb  \\\n",
       "HSPC_025    0.000000  11.117064  2.275971   9.563837       0.0  8.967574   \n",
       "HSPC_031    0.000000   0.686872  5.565109   9.814485       0.0  9.297106   \n",
       "HSPC_037    1.218731   2.933024  2.316800  10.080613       0.0  9.895967   \n",
       "LT-HSC_001  2.364517   6.392249  3.217169   7.150694       0.0  8.671295   \n",
       "HSPC_001    0.000000   0.923649  8.533429   2.288830       0.0  9.603663   \n",
       "\n",
       "              Elovl1     Myo1f      Lax1    Cyp2j6   Pstpip1  Emp1      Cd44  \\\n",
       "HSPC_025    6.893110  8.575464  1.832751  1.189716  8.673779   0.0  9.114851   \n",
       "HSPC_031    5.689649  8.781518  0.000000  9.254531  7.154525   0.0  2.555402   \n",
       "HSPC_037    3.694520  1.218731  7.091666  0.000000  8.692885   0.0  6.490843   \n",
       "LT-HSC_001  6.766791  5.885018  0.000000  2.364517  7.107933   0.0  8.685906   \n",
       "HSPC_001    9.580752  0.000000  0.000000  5.370192  5.712118   0.0  1.482235   \n",
       "\n",
       "               Mtch2      Pgm2  Krt7  Mir155hg  1110028F11Rik     Acot7  Rnd2  \\\n",
       "HSPC_025    3.118771  0.000000   0.0       0.0       0.000000  8.316089   0.0   \n",
       "HSPC_031    7.873747  1.150286   0.0       0.0       1.150286  8.878166   0.0   \n",
       "HSPC_037    8.277468  0.000000   0.0       0.0       0.000000  8.706702   0.0   \n",
       "LT-HSC_001  8.012835  2.364517   0.0       0.0       0.000000  4.137438   0.0   \n",
       "HSPC_001    1.628905  0.000000   0.0       0.0       0.676211  1.134796   0.0   \n",
       "\n",
       "                 Irf1    H2-DMa    Zfp263  Rxra     Klhl6  A130014A01Rik  \\\n",
       "HSPC_025    10.128487  6.968835  7.174734   0.0  8.056275       1.189716   \n",
       "HSPC_031     1.150286  9.615775  1.500480   0.0  1.782055       0.000000   \n",
       "HSPC_037     1.218731  8.833854  3.538458   0.0  8.923351       0.000000   \n",
       "LT-HSC_001   2.364517  3.217169  7.453613   0.0  8.671295       0.000000   \n",
       "HSPC_001     0.923649  7.362259  9.059246   0.0  0.377367       0.000000   \n",
       "\n",
       "               Ssbp2      Rbp1    Rsl1d1  Gjb3     Asah1    Tmem37     Spcs3  \\\n",
       "HSPC_025    7.442493  1.189716  8.848332   0.0  9.296293  0.000000  7.747791   \n",
       "HSPC_031    8.959939  6.853501  9.008575   0.0  4.358484  0.686872  1.782055   \n",
       "HSPC_037    8.271282  1.218731  8.747376   0.0  1.218731  7.324543  2.657566   \n",
       "LT-HSC_001  7.760152  6.160812  3.217169   0.0  8.499976  0.000000  7.520354   \n",
       "HSPC_001    8.791733  5.661887  8.810106   0.0  0.000000  0.000000  1.482235   \n",
       "\n",
       "               Cenpa  Gfpt2   Tmprss3     Pqlc3     Dhrs3      Jak3   Fam213b  \\\n",
       "HSPC_025    2.275971    0.0  1.189716  0.000000  1.832751  7.730490  0.000000   \n",
       "HSPC_031    2.827391    0.0  0.000000  6.623022  0.000000  0.000000  0.000000   \n",
       "HSPC_037    3.363442    0.0  1.869807  0.000000  1.218731  1.869807  1.218731   \n",
       "LT-HSC_001  0.000000    0.0  0.000000  3.749470  7.814354  8.499976  0.000000   \n",
       "HSPC_001    0.377367    0.0  0.000000  0.000000  0.676211  0.676211  0.000000   \n",
       "\n",
       "              Pafah2       Jun     Lamp1   Camsap3     Grtp1   Gm16794  \\\n",
       "HSPC_025    7.999631  7.535083  9.438924  0.000000  1.189716  0.000000   \n",
       "HSPC_031    1.150286  5.672502  2.017546  0.000000  0.686872  0.000000   \n",
       "HSPC_037    1.869807  2.933024  8.825436  0.000000  0.000000  0.000000   \n",
       "LT-HSC_001  6.766791  9.205236  8.102695  2.364517  0.000000  0.000000   \n",
       "HSPC_001    8.979461  7.441317  0.923649  0.000000  0.000000  0.377367   \n",
       "\n",
       "              Cacybp     Slfn8      Stom   H2-DMb1      H2-D1  Oas1c  Tas1r1  \\\n",
       "HSPC_025    7.212608  9.084533  1.189716  0.000000  11.455247    0.0     0.0   \n",
       "HSPC_031    6.248005  4.595264  1.782055  6.876145  10.860805    0.0     0.0   \n",
       "HSPC_037    8.724920  0.000000  2.316800  1.869807  11.461703    0.0     0.0   \n",
       "LT-HSC_001  5.261087  9.089116  0.000000  3.217169  12.063208    0.0     0.0   \n",
       "HSPC_001    8.317878  0.676211  1.318950  8.222906  12.126537    0.0     0.0   \n",
       "\n",
       "               Rab44  4930579K19Rik       Fos     Nedd4    Cyb561  Mapkapk3  \\\n",
       "HSPC_025    1.189716       0.000000  0.000000  6.418716  0.000000  0.000000   \n",
       "HSPC_031    1.150286       1.150286  0.686872  8.236617  0.000000  8.697130   \n",
       "HSPC_037    0.000000       0.000000  2.316800  6.403053  0.000000  1.869807   \n",
       "LT-HSC_001  0.000000       0.000000  8.938628  9.421470  0.000000  3.217169   \n",
       "HSPC_001    0.000000       0.000000  0.676211  0.676211  0.377367  0.676211   \n",
       "\n",
       "              Inpp4b    Ccdc69     Slfn2  Tmem220  2610035D17Rik    Snap23  \\\n",
       "HSPC_025    0.000000  8.748734  1.189716      0.0       1.189716  6.159051   \n",
       "HSPC_031    0.000000  0.686872  0.000000      0.0       8.470365  0.686872   \n",
       "HSPC_037    6.016053  1.218731  0.000000      0.0       1.218731  7.586077   \n",
       "LT-HSC_001  0.000000  5.666688  9.918720      0.0       7.552600  3.217169   \n",
       "HSPC_001    0.000000  0.377367  0.000000      0.0       8.644301  8.425918   \n",
       "\n",
       "               Nprl2    Rasal3  Ighv1-82      Batf  Tmem121      Rrm2  \\\n",
       "HSPC_025    7.494663  8.718340  1.189716  7.649962      0.0  2.614548   \n",
       "HSPC_031    9.470811  6.152300  0.000000  0.000000      0.0  2.697797   \n",
       "HSPC_037    8.036182  9.734499  0.000000  0.000000      0.0  1.218731   \n",
       "LT-HSC_001  3.749470  7.674830  0.000000  2.364517      0.0  4.442877   \n",
       "HSPC_001    0.377367  0.000000  0.000000  0.000000      0.0  2.739936   \n",
       "\n",
       "               Surf4    Zfp386  Mamdc4  B230217C12Rik  Zbtb42     Sstr2  Pld2  \\\n",
       "HSPC_025    1.832751  6.306441     0.0            0.0     0.0  0.000000   0.0   \n",
       "HSPC_031    5.058266  8.477787     0.0            0.0     0.0  8.164863   0.0   \n",
       "HSPC_037    4.783895  1.869807     0.0            0.0     0.0  0.000000   0.0   \n",
       "LT-HSC_001  4.442877  8.499976     0.0            0.0     0.0  0.000000   0.0   \n",
       "HSPC_001    8.959672  0.377367     0.0            0.0     0.0  0.000000   0.0   \n",
       "\n",
       "               Cers5      Ighd       Ighm    Cyp4v3      Limd2    Nlrp1a  \\\n",
       "HSPC_025    7.135838  0.000000   5.253659  4.337438   8.395074  0.000000   \n",
       "HSPC_031    1.150286  0.000000   7.513468  0.000000   5.739898  5.655149   \n",
       "HSPC_037    7.405841  0.000000   9.115131  0.000000   8.911469  0.000000   \n",
       "LT-HSC_001  2.364517  0.000000  12.165795  0.000000   9.215343  0.000000   \n",
       "HSPC_001    0.000000  0.377367   1.883902  0.000000  10.312110  0.000000   \n",
       "\n",
       "                H2-Q6      P4hb       Grn     H2-Q7  Gm10863      Hhex  \\\n",
       "HSPC_025     8.350471  9.714428  8.526184  7.649962      0.0  8.718340   \n",
       "HSPC_031     9.317932  6.701193  0.000000  8.401790      0.0  1.150286   \n",
       "HSPC_037     7.874218  8.911469  2.657566  7.348242      0.0  6.045346   \n",
       "LT-HSC_001  10.471911  5.982925  0.000000  9.322084      0.0  7.674830   \n",
       "HSPC_001     4.124600  8.799498  1.134796  3.360089      0.0  7.558065   \n",
       "\n",
       "               Pcbp4      Tubb5     Itgb7      Gpam      Cbx5   Fam184a  \\\n",
       "HSPC_025    0.000000  10.165970  8.137279  0.000000  7.309000  1.189716   \n",
       "HSPC_031    0.686872   8.460409  0.686872  0.000000  2.946297  0.000000   \n",
       "HSPC_037    1.869807  10.078843  1.218731  1.218731  2.933024  0.000000   \n",
       "LT-HSC_001  0.000000  10.389508  2.364517  0.000000  9.601794  0.000000   \n",
       "HSPC_001    2.374501  10.136633  1.482235  0.000000  7.551182  0.000000   \n",
       "\n",
       "            Tmem106a  Adamtsl5     Cd79b       Nfe2     H2-Ob   Tcp11l2  \\\n",
       "HSPC_025    0.000000       0.0  1.832751   8.641746  7.992392  0.000000   \n",
       "HSPC_031    0.686872       0.0  0.686872   9.285875  1.782055  5.208578   \n",
       "HSPC_037    1.218731       0.0  0.000000   9.000159  7.417090  9.073083   \n",
       "LT-HSC_001  0.000000       0.0  4.442877  10.104202  0.000000  8.361217   \n",
       "HSPC_001    7.451210       0.0  0.676211  10.394527  8.633481  0.377367   \n",
       "\n",
       "              Shisa5    Samd10  Hspa12b     Tcea2      Ctsd     Rgs19  \\\n",
       "HSPC_025    9.331144  7.431828      0.0  1.189716  9.334011  9.403884   \n",
       "HSPC_031    9.719592  0.000000      0.0  9.479464  6.359344  8.380830   \n",
       "HSPC_037    7.383077  1.218731      0.0  2.316800  4.190334  9.083711   \n",
       "LT-HSC_001  9.164084  0.000000      0.0  7.866592  8.700371  8.548753   \n",
       "HSPC_001    9.589737  0.000000      0.0  0.000000  7.974620  9.727375   \n",
       "\n",
       "               Procr     Tnni2     Acap1       Bin2  Ropn1l    Lmbrd2  \\\n",
       "HSPC_025    0.000000  1.189716  9.007623   9.390178     0.0  0.000000   \n",
       "HSPC_031    0.686872  0.000000  9.978684   9.464599     0.0  0.686872   \n",
       "HSPC_037    2.657566  1.218731  3.164226  10.033882     0.0  0.000000   \n",
       "LT-HSC_001  9.143059  0.000000  0.000000   7.965715     0.0  0.000000   \n",
       "HSPC_001    9.550012  0.000000  9.245576   9.297222     0.0  0.000000   \n",
       "\n",
       "             Laptm4b  Il7r     Capsl     Angpt1     Spag1    H2-Ab1     Gfi1b  \\\n",
       "HSPC_025    8.028232   0.0  0.000000   7.721761  0.000000  0.000000  1.189716   \n",
       "HSPC_031    0.686872   0.0  0.000000   2.397399  0.000000  1.150286  2.017546   \n",
       "HSPC_037    2.657566   0.0  0.000000   8.418471  0.000000  1.869807  1.869807   \n",
       "LT-HSC_001  9.033078   0.0  0.000000  10.577548  0.000000  8.564652  2.364517   \n",
       "HSPC_001    8.703439   0.0  0.377367   8.125878  0.377367  0.000000  1.318950   \n",
       "\n",
       "                H2-Aa      Ctsw     Hspa5   Tbc1d10c      Rom1  Smpd2  \\\n",
       "HSPC_025     1.189716  6.581951  8.475161   7.054751  0.000000    0.0   \n",
       "HSPC_031     0.000000  7.574740  9.898919   0.686872  0.000000    0.0   \n",
       "HSPC_037     7.832819  1.218731  9.101251  10.376936  0.000000    0.0   \n",
       "LT-HSC_001  10.987443  0.000000  9.464477   8.824412  0.000000    0.0   \n",
       "HSPC_001     0.676211  0.676211  6.237319   6.833019  0.377367    0.0   \n",
       "\n",
       "                Ctsf      Fgd2      Cct8    Mamdc2     Stip1  Gm28043  \\\n",
       "HSPC_025    0.000000  6.939021  9.742748  6.829531  7.992392      0.0   \n",
       "HSPC_031    0.686872  0.686872  9.306862  0.000000  1.782055      0.0   \n",
       "HSPC_037    8.966101  5.924429  8.489459  0.000000  3.694520      0.0   \n",
       "LT-HSC_001  0.000000  0.000000  9.802852  0.000000  4.137438      0.0   \n",
       "HSPC_001    7.043829  0.000000  8.814903  0.000000  8.390367      0.0   \n",
       "\n",
       "                 Cd27  Rdh5  Aldoc    Prss57    Arpc1b      Fut7      Cd86  \\\n",
       "HSPC_025     8.130700   0.0    0.0  1.189716  9.214658  7.887028  0.000000   \n",
       "HSPC_031    10.211670   0.0    0.0  0.000000  9.347942  2.017546  0.000000   \n",
       "HSPC_037    10.911210   0.0    0.0  1.218731  9.804700  7.439328  1.218731   \n",
       "LT-HSC_001   9.943251   0.0    0.0  0.000000  9.937158  2.364517  0.000000   \n",
       "HSPC_001     8.732122   0.0    0.0  8.673117  9.525641  0.923649  0.000000   \n",
       "\n",
       "             Serpinf1       Cd9   Gm37274  Wdr38   Angptl6  Smad6  Chad  \\\n",
       "HSPC_025     7.399354  2.275971  1.189716    0.0  6.763021    0.0   0.0   \n",
       "HSPC_031     1.782055  7.985573  0.000000    0.0  0.000000    0.0   0.0   \n",
       "HSPC_037     2.657566  1.218731  0.000000    0.0  1.218731    0.0   0.0   \n",
       "LT-HSC_001   8.324337  2.364517  0.000000    0.0  0.000000    0.0   0.0   \n",
       "HSPC_001    10.337334  3.853357  0.000000    0.0  0.676211    0.0   0.0   \n",
       "\n",
       "              Arhgdib      Eogt  Llgl2      Cst7  E130215H24Rik  Gm27201  \\\n",
       "HSPC_025    10.830842  0.000000    0.0  1.832751            0.0      0.0   \n",
       "HSPC_031     8.713988  0.000000    0.0  0.686872            0.0      0.0   \n",
       "HSPC_037    11.608145  0.000000    0.0  0.000000            0.0      0.0   \n",
       "LT-HSC_001  10.420417  0.000000    0.0  2.364517            0.0      0.0   \n",
       "HSPC_001    11.414046  0.377367    0.0  0.923649            0.0      0.0   \n",
       "\n",
       "                Pcna    Rnf114  Gchfr    Cacfd1      Jam3    Fkbp1a      Eps8  \\\n",
       "HSPC_025    8.608986  8.316089    0.0  1.189716  0.000000  9.173640  5.809578   \n",
       "HSPC_031    3.582099  2.219938    0.0  0.686872  0.000000  8.504679  0.000000   \n",
       "HSPC_037    6.309572  2.657566    0.0  0.000000  0.000000  4.081427  0.000000   \n",
       "LT-HSC_001  8.080749  2.364517    0.0  0.000000  8.145608  6.319152  0.000000   \n",
       "HSPC_001    1.628905  0.676211    0.0  0.000000  0.000000  8.230106  0.000000   \n",
       "\n",
       "            Epb41l1     Traf1     Pdia3     Mgst1  Slc2a6  Spint1       Lmo2  \\\n",
       "HSPC_025        0.0  0.000000  9.414757  7.612677     0.0     0.0  10.214998   \n",
       "HSPC_031        0.0  0.000000  7.961069  7.943307     0.0     0.0  11.641084   \n",
       "HSPC_037        0.0  0.000000  8.816968  6.309572     0.0     0.0  10.319646   \n",
       "LT-HSC_001      0.0  8.811145  9.132430  0.000000     0.0     0.0  10.173233   \n",
       "HSPC_001        0.0  0.000000  9.630032  0.000000     0.0     0.0  10.754757   \n",
       "\n",
       "                 Eng     Skap2     Vamp5  Plxna1  Klrb1f   Tmem176b      Mcm2  \\\n",
       "HSPC_025    6.374848  7.545014  6.051698     0.0     0.0   9.921090  8.860312   \n",
       "HSPC_031    6.783355  8.111786  8.133878     0.0     0.0   9.748516  1.150286   \n",
       "HSPC_037    5.485582  7.019698  8.155161     0.0     0.0   9.396608  2.657566   \n",
       "LT-HSC_001  9.676858  7.989468  8.267186     0.0     0.0  10.812068  2.364517   \n",
       "HSPC_001    8.291965  7.555774  9.070521     0.0     0.0   9.177187  1.762030   \n",
       "\n",
       "             Slc52a3      Cct7     Ptgs1      Cnn2     Prim1  Rwdd2a  \\\n",
       "HSPC_025    0.000000  8.815891  9.269591  7.739166  7.545014     0.0   \n",
       "HSPC_031    0.000000  3.787179  0.000000  8.809238  1.782055     0.0   \n",
       "HSPC_037    0.000000  9.122022  0.000000  1.218731  2.933024     0.0   \n",
       "LT-HSC_001  2.364517  9.264843  7.552600  8.580378  2.364517     0.0   \n",
       "HSPC_001    0.000000  8.746254  0.377367  7.629506  1.134796     0.0   \n",
       "\n",
       "                Matk      Atp5b       Cdk4  Robo4   Gm15915   Gm10101  \\\n",
       "HSPC_025    0.000000   9.953140  10.011602    0.0  2.275971  0.000000   \n",
       "HSPC_031    7.454503  10.444765   8.362235    0.0  2.017546  0.000000   \n",
       "HSPC_037    0.000000  10.647927   8.931218    0.0  2.657566  0.000000   \n",
       "LT-HSC_001  8.166596  10.933363   7.732268    0.0  0.000000  0.000000   \n",
       "HSPC_001    0.000000  10.477341  10.039568    0.0  1.318950  0.377367   \n",
       "\n",
       "               Abhd4     Rab36    Metap2      Fzr1     Pa2g4    Smim24  \\\n",
       "HSPC_025    8.110780  0.000000  8.883978  7.273603  9.449536  0.000000   \n",
       "HSPC_031    0.686872  0.000000  5.508257  0.686872  7.615685  0.686872   \n",
       "HSPC_037    9.287452  0.000000  7.866032  3.363442  8.384491  8.114280   \n",
       "LT-HSC_001  2.364517  0.000000  8.166596  8.770595  2.364517  0.000000   \n",
       "HSPC_001    6.563421  0.377367  9.440054  1.134796  1.134796  7.707927   \n",
       "\n",
       "             Gm16104  Perp      Fig4     Myct1      Lsp1  Alpk3  Zfp28  Zfp78  \\\n",
       "HSPC_025    0.000000   0.0  6.282898  1.189716  9.245434    0.0    0.0    0.0   \n",
       "HSPC_031    0.000000   0.0  0.000000  0.000000  7.439376    0.0    0.0    0.0   \n",
       "HSPC_037    0.000000   0.0  8.320036  8.148427  7.615671    0.0    0.0    0.0   \n",
       "LT-HSC_001  2.364517   0.0  0.000000  9.121723  9.481327    0.0    0.0    0.0   \n",
       "HSPC_001    0.000000   0.0  0.377367  5.359726  9.581316    0.0    0.0    0.0   \n",
       "\n",
       "            Zfp773  Mill2      Gpr4  Nectin2    Tyrobp  Plekhf1      Nkg7  \\\n",
       "HSPC_025       0.0    0.0  0.000000      0.0  1.189716      0.0  2.614548   \n",
       "HSPC_031       0.0    0.0  2.827391      0.0  3.158217      0.0  2.219938   \n",
       "HSPC_037       0.0    0.0  0.000000      0.0  7.336441      0.0  8.407233   \n",
       "LT-HSC_001     0.0    0.0  0.000000      0.0  0.000000      0.0  3.749470   \n",
       "HSPC_001       0.0    0.0  0.000000      0.0  0.377367      0.0  1.134796   \n",
       "\n",
       "             Osbpl1a  Slc27a6    Gm4951    Zfp438     Rab18  \n",
       "HSPC_025    0.000000      0.0  0.000000  1.189716  9.263590  \n",
       "HSPC_031    2.017546      0.0  0.000000  0.000000  0.686872  \n",
       "HSPC_037    1.218731      0.0  0.000000  1.218731  8.641061  \n",
       "LT-HSC_001  6.820749      0.0  7.107933  2.364517  6.242153  \n",
       "HSPC_001    1.134796      0.0  1.883902  0.000000  1.318950  "
      ]
     },
     "execution_count": 12,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "ref_data = pd.read_csv(\"data_filtered_vargenes/GSE81682_Hematopoiesis.csv\", index_col=0)\n",
    "ref_data.head()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 13,
   "id": "63997150",
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "CPU times: user 1min 12s, sys: 1.26 s, total: 1min 14s\n",
      "Wall time: 13 s\n"
     ]
    },
    {
     "data": {
      "text/html": [
       "<style>#sk-container-id-1 {\n",
       "  /* Definition of color scheme common for light and dark mode */\n",
       "  --sklearn-color-text: black;\n",
       "  --sklearn-color-line: gray;\n",
       "  /* Definition of color scheme for unfitted estimators */\n",
       "  --sklearn-color-unfitted-level-0: #fff5e6;\n",
       "  --sklearn-color-unfitted-level-1: #f6e4d2;\n",
       "  --sklearn-color-unfitted-level-2: #ffe0b3;\n",
       "  --sklearn-color-unfitted-level-3: chocolate;\n",
       "  /* Definition of color scheme for fitted estimators */\n",
       "  --sklearn-color-fitted-level-0: #f0f8ff;\n",
       "  --sklearn-color-fitted-level-1: #d4ebff;\n",
       "  --sklearn-color-fitted-level-2: #b3dbfd;\n",
       "  --sklearn-color-fitted-level-3: cornflowerblue;\n",
       "\n",
       "  /* Specific color for light theme */\n",
       "  --sklearn-color-text-on-default-background: var(--sg-text-color, var(--theme-code-foreground, var(--jp-content-font-color1, black)));\n",
       "  --sklearn-color-background: var(--sg-background-color, var(--theme-background, var(--jp-layout-color0, white)));\n",
       "  --sklearn-color-border-box: var(--sg-text-color, var(--theme-code-foreground, var(--jp-content-font-color1, black)));\n",
       "  --sklearn-color-icon: #696969;\n",
       "\n",
       "  @media (prefers-color-scheme: dark) {\n",
       "    /* Redefinition of color scheme for dark theme */\n",
       "    --sklearn-color-text-on-default-background: var(--sg-text-color, var(--theme-code-foreground, var(--jp-content-font-color1, white)));\n",
       "    --sklearn-color-background: var(--sg-background-color, var(--theme-background, var(--jp-layout-color0, #111)));\n",
       "    --sklearn-color-border-box: var(--sg-text-color, var(--theme-code-foreground, var(--jp-content-font-color1, white)));\n",
       "    --sklearn-color-icon: #878787;\n",
       "  }\n",
       "}\n",
       "\n",
       "#sk-container-id-1 {\n",
       "  color: var(--sklearn-color-text);\n",
       "}\n",
       "\n",
       "#sk-container-id-1 pre {\n",
       "  padding: 0;\n",
       "}\n",
       "\n",
       "#sk-container-id-1 input.sk-hidden--visually {\n",
       "  border: 0;\n",
       "  clip: rect(1px 1px 1px 1px);\n",
       "  clip: rect(1px, 1px, 1px, 1px);\n",
       "  height: 1px;\n",
       "  margin: -1px;\n",
       "  overflow: hidden;\n",
       "  padding: 0;\n",
       "  position: absolute;\n",
       "  width: 1px;\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-dashed-wrapped {\n",
       "  border: 1px dashed var(--sklearn-color-line);\n",
       "  margin: 0 0.4em 0.5em 0.4em;\n",
       "  box-sizing: border-box;\n",
       "  padding-bottom: 0.4em;\n",
       "  background-color: var(--sklearn-color-background);\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-container {\n",
       "  /* jupyter's `normalize.less` sets `[hidden] { display: none; }`\n",
       "     but bootstrap.min.css set `[hidden] { display: none !important; }`\n",
       "     so we also need the `!important` here to be able to override the\n",
       "     default hidden behavior on the sphinx rendered scikit-learn.org.\n",
       "     See: https://github.com/scikit-learn/scikit-learn/issues/21755 */\n",
       "  display: inline-block !important;\n",
       "  position: relative;\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-text-repr-fallback {\n",
       "  display: none;\n",
       "}\n",
       "\n",
       "div.sk-parallel-item,\n",
       "div.sk-serial,\n",
       "div.sk-item {\n",
       "  /* draw centered vertical line to link estimators */\n",
       "  background-image: linear-gradient(var(--sklearn-color-text-on-default-background), var(--sklearn-color-text-on-default-background));\n",
       "  background-size: 2px 100%;\n",
       "  background-repeat: no-repeat;\n",
       "  background-position: center center;\n",
       "}\n",
       "\n",
       "/* Parallel-specific style estimator block */\n",
       "\n",
       "#sk-container-id-1 div.sk-parallel-item::after {\n",
       "  content: \"\";\n",
       "  width: 100%;\n",
       "  border-bottom: 2px solid var(--sklearn-color-text-on-default-background);\n",
       "  flex-grow: 1;\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-parallel {\n",
       "  display: flex;\n",
       "  align-items: stretch;\n",
       "  justify-content: center;\n",
       "  background-color: var(--sklearn-color-background);\n",
       "  position: relative;\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-parallel-item {\n",
       "  display: flex;\n",
       "  flex-direction: column;\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-parallel-item:first-child::after {\n",
       "  align-self: flex-end;\n",
       "  width: 50%;\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-parallel-item:last-child::after {\n",
       "  align-self: flex-start;\n",
       "  width: 50%;\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-parallel-item:only-child::after {\n",
       "  width: 0;\n",
       "}\n",
       "\n",
       "/* Serial-specific style estimator block */\n",
       "\n",
       "#sk-container-id-1 div.sk-serial {\n",
       "  display: flex;\n",
       "  flex-direction: column;\n",
       "  align-items: center;\n",
       "  background-color: var(--sklearn-color-background);\n",
       "  padding-right: 1em;\n",
       "  padding-left: 1em;\n",
       "}\n",
       "\n",
       "\n",
       "/* Toggleable style: style used for estimator/Pipeline/ColumnTransformer box that is\n",
       "clickable and can be expanded/collapsed.\n",
       "- Pipeline and ColumnTransformer use this feature and define the default style\n",
       "- Estimators will overwrite some part of the style using the `sk-estimator` class\n",
       "*/\n",
       "\n",
       "/* Pipeline and ColumnTransformer style (default) */\n",
       "\n",
       "#sk-container-id-1 div.sk-toggleable {\n",
       "  /* Default theme specific background. It is overwritten whether we have a\n",
       "  specific estimator or a Pipeline/ColumnTransformer */\n",
       "  background-color: var(--sklearn-color-background);\n",
       "}\n",
       "\n",
       "/* Toggleable label */\n",
       "#sk-container-id-1 label.sk-toggleable__label {\n",
       "  cursor: pointer;\n",
       "  display: block;\n",
       "  width: 100%;\n",
       "  margin-bottom: 0;\n",
       "  padding: 0.5em;\n",
       "  box-sizing: border-box;\n",
       "  text-align: center;\n",
       "}\n",
       "\n",
       "#sk-container-id-1 label.sk-toggleable__label-arrow:before {\n",
       "  /* Arrow on the left of the label */\n",
       "  content: \"▸\";\n",
       "  float: left;\n",
       "  margin-right: 0.25em;\n",
       "  color: var(--sklearn-color-icon);\n",
       "}\n",
       "\n",
       "#sk-container-id-1 label.sk-toggleable__label-arrow:hover:before {\n",
       "  color: var(--sklearn-color-text);\n",
       "}\n",
       "\n",
       "/* Toggleable content - dropdown */\n",
       "\n",
       "#sk-container-id-1 div.sk-toggleable__content {\n",
       "  max-height: 0;\n",
       "  max-width: 0;\n",
       "  overflow: hidden;\n",
       "  text-align: left;\n",
       "  /* unfitted */\n",
       "  background-color: var(--sklearn-color-unfitted-level-0);\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-toggleable__content.fitted {\n",
       "  /* fitted */\n",
       "  background-color: var(--sklearn-color-fitted-level-0);\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-toggleable__content pre {\n",
       "  margin: 0.2em;\n",
       "  border-radius: 0.25em;\n",
       "  color: var(--sklearn-color-text);\n",
       "  /* unfitted */\n",
       "  background-color: var(--sklearn-color-unfitted-level-0);\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-toggleable__content.fitted pre {\n",
       "  /* unfitted */\n",
       "  background-color: var(--sklearn-color-fitted-level-0);\n",
       "}\n",
       "\n",
       "#sk-container-id-1 input.sk-toggleable__control:checked~div.sk-toggleable__content {\n",
       "  /* Expand drop-down */\n",
       "  max-height: 200px;\n",
       "  max-width: 100%;\n",
       "  overflow: auto;\n",
       "}\n",
       "\n",
       "#sk-container-id-1 input.sk-toggleable__control:checked~label.sk-toggleable__label-arrow:before {\n",
       "  content: \"▾\";\n",
       "}\n",
       "\n",
       "/* Pipeline/ColumnTransformer-specific style */\n",
       "\n",
       "#sk-container-id-1 div.sk-label input.sk-toggleable__control:checked~label.sk-toggleable__label {\n",
       "  color: var(--sklearn-color-text);\n",
       "  background-color: var(--sklearn-color-unfitted-level-2);\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-label.fitted input.sk-toggleable__control:checked~label.sk-toggleable__label {\n",
       "  background-color: var(--sklearn-color-fitted-level-2);\n",
       "}\n",
       "\n",
       "/* Estimator-specific style */\n",
       "\n",
       "/* Colorize estimator box */\n",
       "#sk-container-id-1 div.sk-estimator input.sk-toggleable__control:checked~label.sk-toggleable__label {\n",
       "  /* unfitted */\n",
       "  background-color: var(--sklearn-color-unfitted-level-2);\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-estimator.fitted input.sk-toggleable__control:checked~label.sk-toggleable__label {\n",
       "  /* fitted */\n",
       "  background-color: var(--sklearn-color-fitted-level-2);\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-label label.sk-toggleable__label,\n",
       "#sk-container-id-1 div.sk-label label {\n",
       "  /* The background is the default theme color */\n",
       "  color: var(--sklearn-color-text-on-default-background);\n",
       "}\n",
       "\n",
       "/* On hover, darken the color of the background */\n",
       "#sk-container-id-1 div.sk-label:hover label.sk-toggleable__label {\n",
       "  color: var(--sklearn-color-text);\n",
       "  background-color: var(--sklearn-color-unfitted-level-2);\n",
       "}\n",
       "\n",
       "/* Label box, darken color on hover, fitted */\n",
       "#sk-container-id-1 div.sk-label.fitted:hover label.sk-toggleable__label.fitted {\n",
       "  color: var(--sklearn-color-text);\n",
       "  background-color: var(--sklearn-color-fitted-level-2);\n",
       "}\n",
       "\n",
       "/* Estimator label */\n",
       "\n",
       "#sk-container-id-1 div.sk-label label {\n",
       "  font-family: monospace;\n",
       "  font-weight: bold;\n",
       "  display: inline-block;\n",
       "  line-height: 1.2em;\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-label-container {\n",
       "  text-align: center;\n",
       "}\n",
       "\n",
       "/* Estimator-specific */\n",
       "#sk-container-id-1 div.sk-estimator {\n",
       "  font-family: monospace;\n",
       "  border: 1px dotted var(--sklearn-color-border-box);\n",
       "  border-radius: 0.25em;\n",
       "  box-sizing: border-box;\n",
       "  margin-bottom: 0.5em;\n",
       "  /* unfitted */\n",
       "  background-color: var(--sklearn-color-unfitted-level-0);\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-estimator.fitted {\n",
       "  /* fitted */\n",
       "  background-color: var(--sklearn-color-fitted-level-0);\n",
       "}\n",
       "\n",
       "/* on hover */\n",
       "#sk-container-id-1 div.sk-estimator:hover {\n",
       "  /* unfitted */\n",
       "  background-color: var(--sklearn-color-unfitted-level-2);\n",
       "}\n",
       "\n",
       "#sk-container-id-1 div.sk-estimator.fitted:hover {\n",
       "  /* fitted */\n",
       "  background-color: var(--sklearn-color-fitted-level-2);\n",
       "}\n",
       "\n",
       "/* Specification for estimator info (e.g. \"i\" and \"?\") */\n",
       "\n",
       "/* Common style for \"i\" and \"?\" */\n",
       "\n",
       ".sk-estimator-doc-link,\n",
       "a:link.sk-estimator-doc-link,\n",
       "a:visited.sk-estimator-doc-link {\n",
       "  float: right;\n",
       "  font-size: smaller;\n",
       "  line-height: 1em;\n",
       "  font-family: monospace;\n",
       "  background-color: var(--sklearn-color-background);\n",
       "  border-radius: 1em;\n",
       "  height: 1em;\n",
       "  width: 1em;\n",
       "  text-decoration: none !important;\n",
       "  margin-left: 1ex;\n",
       "  /* unfitted */\n",
       "  border: var(--sklearn-color-unfitted-level-1) 1pt solid;\n",
       "  color: var(--sklearn-color-unfitted-level-1);\n",
       "}\n",
       "\n",
       ".sk-estimator-doc-link.fitted,\n",
       "a:link.sk-estimator-doc-link.fitted,\n",
       "a:visited.sk-estimator-doc-link.fitted {\n",
       "  /* fitted */\n",
       "  border: var(--sklearn-color-fitted-level-1) 1pt solid;\n",
       "  color: var(--sklearn-color-fitted-level-1);\n",
       "}\n",
       "\n",
       "/* On hover */\n",
       "div.sk-estimator:hover .sk-estimator-doc-link:hover,\n",
       ".sk-estimator-doc-link:hover,\n",
       "div.sk-label-container:hover .sk-estimator-doc-link:hover,\n",
       ".sk-estimator-doc-link:hover {\n",
       "  /* unfitted */\n",
       "  background-color: var(--sklearn-color-unfitted-level-3);\n",
       "  color: var(--sklearn-color-background);\n",
       "  text-decoration: none;\n",
       "}\n",
       "\n",
       "div.sk-estimator.fitted:hover .sk-estimator-doc-link.fitted:hover,\n",
       ".sk-estimator-doc-link.fitted:hover,\n",
       "div.sk-label-container:hover .sk-estimator-doc-link.fitted:hover,\n",
       ".sk-estimator-doc-link.fitted:hover {\n",
       "  /* fitted */\n",
       "  background-color: var(--sklearn-color-fitted-level-3);\n",
       "  color: var(--sklearn-color-background);\n",
       "  text-decoration: none;\n",
       "}\n",
       "\n",
       "/* Span, style for the box shown on hovering the info icon */\n",
       ".sk-estimator-doc-link span {\n",
       "  display: none;\n",
       "  z-index: 9999;\n",
       "  position: relative;\n",
       "  font-weight: normal;\n",
       "  right: .2ex;\n",
       "  padding: .5ex;\n",
       "  margin: .5ex;\n",
       "  width: min-content;\n",
       "  min-width: 20ex;\n",
       "  max-width: 50ex;\n",
       "  color: var(--sklearn-color-text);\n",
       "  box-shadow: 2pt 2pt 4pt #999;\n",
       "  /* unfitted */\n",
       "  background: var(--sklearn-color-unfitted-level-0);\n",
       "  border: .5pt solid var(--sklearn-color-unfitted-level-3);\n",
       "}\n",
       "\n",
       ".sk-estimator-doc-link.fitted span {\n",
       "  /* fitted */\n",
       "  background: var(--sklearn-color-fitted-level-0);\n",
       "  border: var(--sklearn-color-fitted-level-3);\n",
       "}\n",
       "\n",
       ".sk-estimator-doc-link:hover span {\n",
       "  display: block;\n",
       "}\n",
       "\n",
       "/* \"?\"-specific style due to the `<a>` HTML tag */\n",
       "\n",
       "#sk-container-id-1 a.estimator_doc_link {\n",
       "  float: right;\n",
       "  font-size: 1rem;\n",
       "  line-height: 1em;\n",
       "  font-family: monospace;\n",
       "  background-color: var(--sklearn-color-background);\n",
       "  border-radius: 1rem;\n",
       "  height: 1rem;\n",
       "  width: 1rem;\n",
       "  text-decoration: none;\n",
       "  /* unfitted */\n",
       "  color: var(--sklearn-color-unfitted-level-1);\n",
       "  border: var(--sklearn-color-unfitted-level-1) 1pt solid;\n",
       "}\n",
       "\n",
       "#sk-container-id-1 a.estimator_doc_link.fitted {\n",
       "  /* fitted */\n",
       "  border: var(--sklearn-color-fitted-level-1) 1pt solid;\n",
       "  color: var(--sklearn-color-fitted-level-1);\n",
       "}\n",
       "\n",
       "/* On hover */\n",
       "#sk-container-id-1 a.estimator_doc_link:hover {\n",
       "  /* unfitted */\n",
       "  background-color: var(--sklearn-color-unfitted-level-3);\n",
       "  color: var(--sklearn-color-background);\n",
       "  text-decoration: none;\n",
       "}\n",
       "\n",
       "#sk-container-id-1 a.estimator_doc_link.fitted:hover {\n",
       "  /* fitted */\n",
       "  background-color: var(--sklearn-color-fitted-level-3);\n",
       "}\n",
       "</style><div id=\"sk-container-id-1\" class=\"sk-top-container\"><div class=\"sk-text-repr-fallback\"><pre>scBoolSeqBinarizer()</pre><b>In a Jupyter environment, please rerun this cell to show the HTML representation or trust the notebook. <br />On GitHub, the HTML representation is unable to render, please try loading this page with nbviewer.org.</b></div><div class=\"sk-container\" hidden><div class=\"sk-item\"><div class=\"sk-estimator fitted sk-toggleable\"><input class=\"sk-toggleable__control sk-hidden--visually\" id=\"sk-estimator-id-1\" type=\"checkbox\" checked><label for=\"sk-estimator-id-1\" class=\"sk-toggleable__label fitted sk-toggleable__label-arrow fitted\">&nbsp;scBoolSeqBinarizer<span class=\"sk-estimator-doc-link fitted\">i<span>Fitted</span></span></label><div class=\"sk-toggleable__content fitted\"><pre>scBoolSeqBinarizer()</pre></div> </div></div></div></div>"
      ],
      "text/plain": [
       "scBoolSeqBinarizer()"
      ]
     },
     "execution_count": 13,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "%time scbool = scBoolSeq().fit(ref_data)\n",
    "scbool"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "7104ed5d",
   "metadata": {},
   "source": [
    "## Generate synthetic RNA-Seq data"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 14,
   "id": "898fe99c",
   "metadata": {},
   "outputs": [],
   "source": [
    "SEED = 1928327465\n",
    "n_samples = 200\n",
    "synth_pseudocounts = scbool.sample_counts(binstates, n_samples_per_state=n_samples, random_state=SEED)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 15,
   "id": "72543a7e",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "(3200, 16)"
      ]
     },
     "execution_count": 15,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "synth_pseudocounts.shape"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "4706aa01",
   "metadata": {},
   "source": [
    "We generate unique identifiers for each row (cell):"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 16,
   "id": "74f3ed30",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>G1</th>\n",
       "      <th>G2</th>\n",
       "      <th>G3</th>\n",
       "      <th>G4</th>\n",
       "      <th>G5</th>\n",
       "      <th>G6</th>\n",
       "      <th>G7</th>\n",
       "      <th>G8</th>\n",
       "      <th>G9</th>\n",
       "      <th>TF1</th>\n",
       "      <th>TF2</th>\n",
       "      <th>TF3</th>\n",
       "      <th>TF4</th>\n",
       "      <th>TF5</th>\n",
       "      <th>TF6</th>\n",
       "      <th>TF7</th>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>cellID</th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>common.0_0</th>\n",
       "      <td>0.847507</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.00000</td>\n",
       "      <td>2.202036</td>\n",
       "      <td>2.614669</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>9.352732</td>\n",
       "      <td>10.004515</td>\n",
       "      <td>0.963155</td>\n",
       "      <td>4.000300</td>\n",
       "      <td>2.489920</td>\n",
       "      <td>4.472291</td>\n",
       "      <td>4.386781</td>\n",
       "      <td>6.781031</td>\n",
       "      <td>0.630191</td>\n",
       "      <td>15.730247</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>common.1_0</th>\n",
       "      <td>0.321988</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.00000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>10.117821</td>\n",
       "      <td>9.609912</td>\n",
       "      <td>2.106883</td>\n",
       "      <td>3.594291</td>\n",
       "      <td>0.550599</td>\n",
       "      <td>4.498179</td>\n",
       "      <td>4.402592</td>\n",
       "      <td>6.796882</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>15.391955</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>common.2_0</th>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.200185</td>\n",
       "      <td>0.00000</td>\n",
       "      <td>1.383530</td>\n",
       "      <td>6.155153</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>8.324763</td>\n",
       "      <td>8.316448</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>4.265329</td>\n",
       "      <td>2.632206</td>\n",
       "      <td>3.231189</td>\n",
       "      <td>2.714706</td>\n",
       "      <td>6.547808</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>16.391708</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>common.3_0</th>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.00000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.067945</td>\n",
       "      <td>8.223393</td>\n",
       "      <td>9.823405</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>4.297140</td>\n",
       "      <td>1.624660</td>\n",
       "      <td>4.489941</td>\n",
       "      <td>4.416064</td>\n",
       "      <td>15.693726</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>15.618268</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>common.4_0</th>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.00000</td>\n",
       "      <td>0.192171</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>10.799113</td>\n",
       "      <td>9.326198</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>3.919285</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>1.386326</td>\n",
       "      <td>10.849850</td>\n",
       "      <td>11.264220</td>\n",
       "      <td>0.204638</td>\n",
       "      <td>15.620454</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>...</th>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>stable1_199</th>\n",
       "      <td>4.547110</td>\n",
       "      <td>0.639021</td>\n",
       "      <td>1.36129</td>\n",
       "      <td>3.077207</td>\n",
       "      <td>2.026706</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>1.959658</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.372315</td>\n",
       "      <td>11.318986</td>\n",
       "      <td>0.599283</td>\n",
       "      <td>12.413190</td>\n",
       "      <td>9.778069</td>\n",
       "      <td>9.765420</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>16.297468</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch2.0_199</th>\n",
       "      <td>1.351856</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.00000</td>\n",
       "      <td>3.434270</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>2.644374</td>\n",
       "      <td>1.170639</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>3.296042</td>\n",
       "      <td>6.938048</td>\n",
       "      <td>7.827090</td>\n",
       "      <td>7.870819</td>\n",
       "      <td>10.638463</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>16.106609</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch2.1_199</th>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.00000</td>\n",
       "      <td>7.470441</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.176651</td>\n",
       "      <td>2.826096</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>2.895368</td>\n",
       "      <td>7.974349</td>\n",
       "      <td>7.897861</td>\n",
       "      <td>7.113470</td>\n",
       "      <td>10.292293</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>15.975887</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch2.2_199</th>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.00000</td>\n",
       "      <td>8.211761</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.057849</td>\n",
       "      <td>1.184580</td>\n",
       "      <td>1.397567</td>\n",
       "      <td>0.425407</td>\n",
       "      <td>1.569978</td>\n",
       "      <td>8.665144</td>\n",
       "      <td>9.697807</td>\n",
       "      <td>7.716815</td>\n",
       "      <td>9.060840</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>15.739704</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>stable2_199</th>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.207203</td>\n",
       "      <td>0.00000</td>\n",
       "      <td>9.293637</td>\n",
       "      <td>6.933310</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.912710</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>1.823326</td>\n",
       "      <td>9.258341</td>\n",
       "      <td>10.846124</td>\n",
       "      <td>10.014367</td>\n",
       "      <td>9.936871</td>\n",
       "      <td>0.000000</td>\n",
       "      <td>15.507192</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "<p>3200 rows × 16 columns</p>\n",
       "</div>"
      ],
      "text/plain": [
       "                     G1        G2       G3        G4        G5        G6  \\\n",
       "cellID                                                                     \n",
       "common.0_0     0.847507  0.000000  0.00000  2.202036  2.614669  0.000000   \n",
       "common.1_0     0.321988  0.000000  0.00000  0.000000  0.000000  0.000000   \n",
       "common.2_0     0.000000  0.200185  0.00000  1.383530  6.155153  0.000000   \n",
       "common.3_0     0.000000  0.000000  0.00000  0.000000  0.000000  0.067945   \n",
       "common.4_0     0.000000  0.000000  0.00000  0.192171  0.000000  0.000000   \n",
       "...                 ...       ...      ...       ...       ...       ...   \n",
       "stable1_199    4.547110  0.639021  1.36129  3.077207  2.026706  0.000000   \n",
       "branch2.0_199  1.351856  0.000000  0.00000  3.434270  0.000000  0.000000   \n",
       "branch2.1_199  0.000000  0.000000  0.00000  7.470441  0.000000  0.176651   \n",
       "branch2.2_199  0.000000  0.000000  0.00000  8.211761  0.000000  0.057849   \n",
       "stable2_199    0.000000  0.207203  0.00000  9.293637  6.933310  0.000000   \n",
       "\n",
       "                      G7         G8        G9        TF1       TF2        TF3  \\\n",
       "cellID                                                                          \n",
       "common.0_0      9.352732  10.004515  0.963155   4.000300  2.489920   4.472291   \n",
       "common.1_0     10.117821   9.609912  2.106883   3.594291  0.550599   4.498179   \n",
       "common.2_0      8.324763   8.316448  0.000000   4.265329  2.632206   3.231189   \n",
       "common.3_0      8.223393   9.823405  0.000000   4.297140  1.624660   4.489941   \n",
       "common.4_0     10.799113   9.326198  0.000000   3.919285  0.000000   1.386326   \n",
       "...                  ...        ...       ...        ...       ...        ...   \n",
       "stable1_199     1.959658   0.000000  0.372315  11.318986  0.599283  12.413190   \n",
       "branch2.0_199   2.644374   1.170639  0.000000   3.296042  6.938048   7.827090   \n",
       "branch2.1_199   2.826096   0.000000  0.000000   2.895368  7.974349   7.897861   \n",
       "branch2.2_199   1.184580   1.397567  0.425407   1.569978  8.665144   9.697807   \n",
       "stable2_199     0.912710   0.000000  0.000000   1.823326  9.258341  10.846124   \n",
       "\n",
       "                     TF4        TF5       TF6        TF7  \n",
       "cellID                                                    \n",
       "common.0_0      4.386781   6.781031  0.630191  15.730247  \n",
       "common.1_0      4.402592   6.796882  0.000000  15.391955  \n",
       "common.2_0      2.714706   6.547808  0.000000  16.391708  \n",
       "common.3_0      4.416064  15.693726  0.000000  15.618268  \n",
       "common.4_0     10.849850  11.264220  0.204638  15.620454  \n",
       "...                  ...        ...       ...        ...  \n",
       "stable1_199     9.778069   9.765420  0.000000  16.297468  \n",
       "branch2.0_199   7.870819  10.638463  0.000000  16.106609  \n",
       "branch2.1_199   7.113470  10.292293  0.000000  15.975887  \n",
       "branch2.2_199   7.716815   9.060840  0.000000  15.739704  \n",
       "stable2_199    10.014367   9.936871  0.000000  15.507192  \n",
       "\n",
       "[3200 rows x 16 columns]"
      ]
     },
     "execution_count": 16,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "ids = [f\"{x}_{y}\"  for y in range(n_samples) for x in binstates.index]\n",
    "synth_pseudocounts.index = ids\n",
    "synth_pseudocounts.index.name = \"cellID\"\n",
    "synth_pseudocounts"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "4bfea926",
   "metadata": {},
   "source": [
    "Write as TSV file:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 17,
   "id": "52ec366c",
   "metadata": {},
   "outputs": [],
   "source": [
    "synth_pseudocounts.T.to_csv(\"synthetic_data_reprogramming_counts.tsv\", sep=\"\\t\")"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "cbe1f35d",
   "metadata": {},
   "source": [
    "We generate metadata to validate a trajectory reconstruction:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 18,
   "id": "2e43c375",
   "metadata": {},
   "outputs": [],
   "source": [
    "def label_of_index(idx):\n",
    "    return idx.split(\".\")[0]\n",
    "labels = [label_of_index(idx) for idx in binstates.index]\n",
    "\n",
    "color_map = {\n",
    "    \"common\": \"#aec7e8\",\n",
    "    \"switch\": \"#1f78b4\",\n",
    "    \"branch1\": \"#98df8a\",\n",
    "    \"stable1\": \"#2ca02c\",\n",
    "    \"branch2\": \"#ff9896\",\n",
    "    \"stable2\": \"#d62728\"\n",
    "}"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 19,
   "id": "b01f3016",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>label</th>\n",
       "      <th>label_color</th>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>cellID</th>\n",
       "      <th></th>\n",
       "      <th></th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>common.0_0</th>\n",
       "      <td>common</td>\n",
       "      <td>#aec7e8</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>common.1_0</th>\n",
       "      <td>common</td>\n",
       "      <td>#aec7e8</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>common.2_0</th>\n",
       "      <td>common</td>\n",
       "      <td>#aec7e8</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>common.3_0</th>\n",
       "      <td>common</td>\n",
       "      <td>#aec7e8</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>common.4_0</th>\n",
       "      <td>common</td>\n",
       "      <td>#aec7e8</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>...</th>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>stable1_199</th>\n",
       "      <td>stable1</td>\n",
       "      <td>#2ca02c</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch2.0_199</th>\n",
       "      <td>branch2</td>\n",
       "      <td>#ff9896</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch2.1_199</th>\n",
       "      <td>branch2</td>\n",
       "      <td>#ff9896</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch2.2_199</th>\n",
       "      <td>branch2</td>\n",
       "      <td>#ff9896</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>stable2_199</th>\n",
       "      <td>stable2</td>\n",
       "      <td>#d62728</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "<p>3200 rows × 2 columns</p>\n",
       "</div>"
      ],
      "text/plain": [
       "                 label label_color\n",
       "cellID                            \n",
       "common.0_0      common     #aec7e8\n",
       "common.1_0      common     #aec7e8\n",
       "common.2_0      common     #aec7e8\n",
       "common.3_0      common     #aec7e8\n",
       "common.4_0      common     #aec7e8\n",
       "...                ...         ...\n",
       "stable1_199    stable1     #2ca02c\n",
       "branch2.0_199  branch2     #ff9896\n",
       "branch2.1_199  branch2     #ff9896\n",
       "branch2.2_199  branch2     #ff9896\n",
       "stable2_199    stable2     #d62728\n",
       "\n",
       "[3200 rows x 2 columns]"
      ]
     },
     "execution_count": 19,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "metadata = [[l, color_map[l]] for l in labels]*n_samples\n",
    "metadata = pd.DataFrame(metadata, columns=[\"label\", \"label_color\"])\n",
    "metadata.index = synth_pseudocounts.index\n",
    "metadata"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 20,
   "id": "e6ff610b",
   "metadata": {},
   "outputs": [],
   "source": [
    "metadata.to_csv(\"synthetic_data_reprogramming_metadata.tsv\", sep=\"\\t\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 21,
   "id": "af334bf8",
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "CPU times: user 3.41 s, sys: 580 ms, total: 3.99 s\n",
      "Wall time: 558 ms\n"
     ]
    }
   ],
   "source": [
    "%time synth_scbool = scBoolSeq().fit(synth_pseudocounts)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 22,
   "id": "f62c13d7",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "Category\n",
       "Bimodal     8\n",
       "ZeroInf     6\n",
       "Unimodal    2\n",
       "Name: count, dtype: int64"
      ]
     },
     "execution_count": 22,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "synth_scbool.criteria_.Category.value_counts()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 23,
   "id": "7783ec86",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "<Axes: xlabel='Mean', ylabel='Variance'>"
      ]
     },
     "execution_count": 23,
     "metadata": {},
     "output_type": "execute_result"
    },
    {
     "data": {
      "image/png": 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",
      "text/plain": [
       "<Figure size 640x480 with 1 Axes>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "synth_scbool.criteria_.plot.scatter(x=\"Mean\", y=\"Variance\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 24,
   "id": "0867daf6",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "<Axes: xlabel='Mean', ylabel='DropOutRate'>"
      ]
     },
     "execution_count": 24,
     "metadata": {},
     "output_type": "execute_result"
    },
    {
     "data": {
      "image/png": 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",
      "text/plain": [
       "<Figure size 640x480 with 1 Axes>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "synth_scbool.criteria_.plot.scatter(x=\"Mean\", y=\"DropOutRate\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 25,
   "id": "595d866c",
   "metadata": {},
   "outputs": [],
   "source": [
    "from sklearn.manifold import TSNE"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 26,
   "id": "6b4d9306",
   "metadata": {},
   "outputs": [],
   "source": [
    "from sklearn.pipeline import Pipeline, FunctionTransformer"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 27,
   "id": "e6375ee4",
   "metadata": {},
   "outputs": [],
   "source": [
    "from sklearn.manifold import LocallyLinearEmbedding, SpectralEmbedding"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 49,
   "id": "1ef8e6ff",
   "metadata": {},
   "outputs": [],
   "source": [
    "def rename_columns(df):\n",
    "    \"\"\" \"\"\"\n",
    "    df = pd.DataFrame(df, index=metadata.index)\n",
    "    df.columns = [f\"dim{i}\" for i in range(df.shape[1])]\n",
    "    return df"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 50,
   "id": "30dbfe42",
   "metadata": {},
   "outputs": [],
   "source": [
    "vis_pipeline = Pipeline([\n",
    "    ('pca', PCA()),\n",
    "    ('subset_pca', FunctionTransformer(lambda x: x.iloc[:, :4] if isinstance(x, pd.DataFrame) else x[:, ][:, :4])),\n",
    "    ('lle', LocallyLinearEmbedding(n_neighbors=300, n_components=2, random_state=SEED)),\n",
    "    ('rename_cols', FunctionTransformer(rename_columns))\n",
    "])"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 51,
   "id": "bff05dfb",
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "CPU times: user 17.8 s, sys: 1.38 s, total: 19.1 s\n",
      "Wall time: 6.71 s\n"
     ]
    }
   ],
   "source": [
    "%time aa = vis_pipeline.fit_transform(synth_pseudocounts)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 52,
   "id": "943e20f8",
   "metadata": {},
   "outputs": [
    {
     "data": {
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      ],
      "text/plain": [
       "                   dim0      dim1\n",
       "cellID                           \n",
       "common.0_0     0.023828 -0.000833\n",
       "common.1_0     0.025914 -0.005112\n",
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       "...                 ...       ...\n",
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       "stable2_199   -0.018215  0.041707\n",
       "\n",
       "[3200 rows x 2 columns]"
      ]
     },
     "execution_count": 52,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "aa"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 53,
   "id": "fdba5852-a11c-40f6-ad60-e9f889de3846",
   "metadata": {},
   "outputs": [
    {
     "data": {
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       "      <td>stable1</td>\n",
       "      <td>#2ca02c</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch2.0_199</th>\n",
       "      <td>branch2</td>\n",
       "      <td>#ff9896</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch2.1_199</th>\n",
       "      <td>branch2</td>\n",
       "      <td>#ff9896</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>branch2.2_199</th>\n",
       "      <td>branch2</td>\n",
       "      <td>#ff9896</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>stable2_199</th>\n",
       "      <td>stable2</td>\n",
       "      <td>#d62728</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "<p>3200 rows × 2 columns</p>\n",
       "</div>"
      ],
      "text/plain": [
       "                 label label_color\n",
       "cellID                            \n",
       "common.0_0      common     #aec7e8\n",
       "common.1_0      common     #aec7e8\n",
       "common.2_0      common     #aec7e8\n",
       "common.3_0      common     #aec7e8\n",
       "common.4_0      common     #aec7e8\n",
       "...                ...         ...\n",
       "stable1_199    stable1     #2ca02c\n",
       "branch2.0_199  branch2     #ff9896\n",
       "branch2.1_199  branch2     #ff9896\n",
       "branch2.2_199  branch2     #ff9896\n",
       "stable2_199    stable2     #d62728\n",
       "\n",
       "[3200 rows x 2 columns]"
      ]
     },
     "execution_count": 53,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "metadata"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 54,
   "id": "893edf1e",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>dim0</th>\n",
       "      <th>dim1</th>\n",
       "      <th>label</th>\n",
       "      <th>label_color</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>0.023828</td>\n",
       "      <td>-0.000833</td>\n",
       "      <td>common</td>\n",
       "      <td>#aec7e8</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>0.025914</td>\n",
       "      <td>-0.005112</td>\n",
       "      <td>common</td>\n",
       "      <td>#aec7e8</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>0.023909</td>\n",
       "      <td>0.000395</td>\n",
       "      <td>common</td>\n",
       "      <td>#aec7e8</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>0.019406</td>\n",
       "      <td>-0.003988</td>\n",
       "      <td>common</td>\n",
       "      <td>#aec7e8</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>0.020854</td>\n",
       "      <td>-0.005976</td>\n",
       "      <td>common</td>\n",
       "      <td>#aec7e8</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "       dim0      dim1   label label_color\n",
       "0  0.023828 -0.000833  common     #aec7e8\n",
       "1  0.025914 -0.005112  common     #aec7e8\n",
       "2  0.023909  0.000395  common     #aec7e8\n",
       "3  0.019406 -0.003988  common     #aec7e8\n",
       "4  0.020854 -0.005976  common     #aec7e8"
      ]
     },
     "execution_count": 54,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "vis_frame = aa.join(metadata)\n",
    "vis_frame.index.name = \"index\"\n",
    "vis_frame = vis_frame.reset_index().drop(\"index\", axis=\"columns\")\n",
    "vis_frame.head()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 56,
   "id": "a51e1fe4",
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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",
      "text/plain": [
       "<Figure size 640x480 with 1 Axes>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "ax = None\n",
    "for label, frame in vis_frame.groupby('label'):\n",
    "    scatter_kwargs = dict(x='dim0', y='dim1', label=label, c=frame['label_color'], alpha=.8)\n",
    "    if ax is not None:\n",
    "        scatter_kwargs.update({'ax': ax})\n",
    "    ax = frame.plot.scatter(**scatter_kwargs)\n",
    "\n"
   ]
  },
  {
   "cell_type": "markdown",
   "id": "3ae3a09f",
   "metadata": {},
   "source": [
    "fig = ax.get_figure()\n",
    "for _f in ['svg', 'pdf', 'png']:\n",
    "    fig.savefig(f\"reprogramming_network.{_f}\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "id": "389210d8-aeb3-4730-923d-13315f99a154",
   "metadata": {},
   "outputs": [],
   "source": []
  }
 ],
 "metadata": {
  "kernelspec": {
   "display_name": "Python 3 (ipykernel)",
   "language": "python",
   "name": "python3"
  },
  "language_info": {
   "codemirror_mode": {
    "name": "ipython",
    "version": 3
   },
   "file_extension": ".py",
   "mimetype": "text/x-python",
   "name": "python",
   "nbconvert_exporter": "python",
   "pygments_lexer": "ipython3",
   "version": "3.11.7"
  }
 },
 "nbformat": 4,
 "nbformat_minor": 5
}