diff --git a/src/platforms/stlink/Makefile.inc b/src/platforms/stlink/Makefile.inc
index d10878a4e62..2442af08c4b 100644
--- a/src/platforms/stlink/Makefile.inc
+++ b/src/platforms/stlink/Makefile.inc
@@ -39,6 +39,10 @@ ifeq ($(STLINK_FORCE_CLONE), 1)
 CFLAGS += -DSTLINK_FORCE_CLONE=1
 endif
 
+ifeq ($(STLINK_V2_ISOL), 1)
+CFLAGS += -DSTLINK_V2_ISOL=1
+endif
+
 VPATH += platforms/common/stm32
 
 SRC +=          \
diff --git a/src/platforms/stlink/platform.c b/src/platforms/stlink/platform.c
index 191a1fbbae6..243941c5507 100644
--- a/src/platforms/stlink/platform.c
+++ b/src/platforms/stlink/platform.c
@@ -51,6 +51,19 @@ void platform_init(void)
 #ifdef BLUEPILL
 	led_idle_run = GPIO13;
 	nrst_pin = NRST_PIN_V1;
+#elif defined(STLINK_V2_ISOL)
+	led_idle_run = GPIO9;
+	nrst_pin = NRST_PIN_V2;
+	/* PB12 is SWDIO_IN */
+	gpio_set_mode(GPIOB, GPIO_MODE_INPUT, GPIO_CNF_INPUT_FLOAT, GPIO12);
+	/* PA4 is used to set SWDCLK floating when set to 1 */
+	gpio_set_mode(GPIOA, GPIO_MODE_OUTPUT_2_MHZ, GPIO_CNF_OUTPUT_PUSHPULL, GPIO4);
+	gpio_clear(GPIOA, GPIO4);
+	/* PA1 is used to set SWDIO floating and MUXED to SWDIO_IN when set to 1 */
+	gpio_set_mode(GPIOA, GPIO_MODE_OUTPUT_2_MHZ, GPIO_CNF_OUTPUT_PUSHPULL, GPIO1);
+#elif defined(STLINK_FORCE_CLONE)
+	led_idle_run = GPIO9;
+	nrst_pin = NRST_PIN_CLONE;
 #else
 	switch (rev) {
 	case 0:
@@ -68,7 +81,13 @@ void platform_init(void)
 	}
 #endif
 	/* Setup GPIO ports */
+#ifdef STLINK_V2_ISOL
+	/* In case of ISOL variant, this pin is never set to high impedance */
+	gpio_set_mode(TMS_PORT, GPIO_MODE_OUTPUT_2_MHZ, GPIO_CNF_OUTPUT_PUSHPULL, TMS_PIN);
+#else
+	/* In all other variants, this pin is initialized as high impedance */
 	gpio_set_mode(TMS_PORT, GPIO_MODE_OUTPUT_2_MHZ, GPIO_CNF_INPUT_FLOAT, TMS_PIN);
+#endif
 	gpio_set_mode(TCK_PORT, GPIO_MODE_OUTPUT_2_MHZ, GPIO_CNF_OUTPUT_PUSHPULL, TCK_PIN);
 	gpio_set_mode(TDI_PORT, GPIO_MODE_OUTPUT_2_MHZ, GPIO_CNF_OUTPUT_PUSHPULL, TDI_PIN);
 
diff --git a/src/platforms/stlink/platform.h b/src/platforms/stlink/platform.h
index fa56aa105e7..34ba4533e37 100644
--- a/src/platforms/stlink/platform.h
+++ b/src/platforms/stlink/platform.h
@@ -53,6 +53,11 @@ extern bool debug_bmp;
 #define SWDIO_PIN  TMS_PIN
 #define SWCLK_PIN  TCK_PIN
 
+#ifdef STLINK_V2_ISOL
+#define SWDIO_IN_PORT GPIOB
+#define SWDIO_IN_PIN  GPIO12
+#endif
+
 #define NRST_PORT      GPIOB
 #define NRST_PIN_V1    GPIO1
 #define NRST_PIN_V2    GPIO0
@@ -78,6 +83,19 @@ extern bool debug_bmp;
 #define SWD_CR_MULT (1U << ((14U - 8U) << 2U))
 
 #define TMS_SET_MODE() gpio_set_mode(TMS_PORT, GPIO_MODE_OUTPUT_2_MHZ, GPIO_CNF_OUTPUT_PUSHPULL, TMS_PIN);
+
+#ifdef STLINK_V2_ISOL
+/* The ISOL variant floats SWDIO with GPIO A1 */
+#define SWDIO_MODE_FLOAT()      \
+	do {                        \
+		gpio_set(GPIOA, GPIO1); \
+	} while (0)
+#define SWDIO_MODE_DRIVE()        \
+	do {                          \
+		gpio_clear(GPIOA, GPIO1); \
+	} while (0)
+#else
+/* All other variants just set SWDIO_PIN to floating */
 #define SWDIO_MODE_FLOAT()           \
 	do {                             \
 		uint32_t cr = SWD_CR;        \
@@ -92,6 +110,7 @@ extern bool debug_bmp;
 		cr |= (0x1U * SWD_CR_MULT);  \
 		SWD_CR = cr;                 \
 	} while (0)
+#endif
 #define UART_PIN_SETUP()                                                                                        \
 	do {                                                                                                        \
 		gpio_set_mode(USBUSART_PORT, GPIO_MODE_OUTPUT_50_MHZ, GPIO_CNF_OUTPUT_ALTFN_PUSHPULL, USBUSART_TX_PIN); \
diff --git a/src/platforms/stlink/stlink_common.c b/src/platforms/stlink/stlink_common.c
index 3f638c21cbe..0e9df492796 100644
--- a/src/platforms/stlink/stlink_common.c
+++ b/src/platforms/stlink/stlink_common.c
@@ -25,6 +25,8 @@
 
 #include "platform.h"
 
+/* If we force CLONE or V2_ISOL variant, we don't need to read GPIO levels */
+#if !(defined(STLINK_FORCE_CLONE) || defined(STLINK_V2_ISOL))
 static bool stlink_stable_read(const uint32_t gpio_port, const uint16_t gpio)
 {
 	bool result = false;
@@ -32,6 +34,7 @@ static bool stlink_stable_read(const uint32_t gpio_port, const uint16_t gpio)
 		result = gpio_get(gpio_port, gpio);
 	return result;
 }
+#endif
 
 /* Return 0 for ST-Link v1, 1 for ST-Link v2 and 2 for ST-Link v2.1 */
 uint32_t detect_rev(void)
@@ -45,6 +48,17 @@ uint32_t detect_rev(void)
 	rcc_periph_reset_pulse(RST_USB);
 	rcc_periph_clock_enable(RCC_AFIO);
 	rcc_periph_clock_enable(RCC_CRC);
+
+#if defined(STLINK_FORCE_CLONE)
+	/* PA12 is USB D+ pin */
+	gpio_clear(GPIOA, GPIO12);
+	gpio_set_mode(GPIOA, GPIO_MODE_OUTPUT_2_MHZ, GPIO_CNF_OUTPUT_OPENDRAIN, GPIO12);
+	/* Override detection to use clone pinmap (i.e. PB6 as nRST). */
+	return 0x101;
+#elif defined(STLINK_V2_ISOL)
+	/* Override detection to stlink v2 isol*/
+	return 0x103;
+#else
 	/*
 	 * First, get the board revision by pulling PC13/14 up then reading them.
 	 * This gives us the following table of values for these pins:
@@ -89,16 +103,13 @@ uint32_t detect_rev(void)
 		gpio_set_mode(GPIOA, GPIO_MODE_OUTPUT_50_MHZ, GPIO_CNF_OUTPUT_ALTFN_PUSHPULL, GPIO8);
 	}
 
-	/* Override detection to use clone pinmap (i.e. PB6 as nRST). */
-#if defined(STLINK_FORCE_CLONE)
-	revision = 0x101;
-#endif
 	/* Clean up after ourself on boards that aren't identified as ST-Link v2.1's */
 	if ((revision & 0xff) < 2U) {
 		gpio_clear(GPIOA, GPIO12);
 		gpio_set_mode(GPIOA, GPIO_MODE_OUTPUT_2_MHZ, GPIO_CNF_OUTPUT_OPENDRAIN, GPIO12);
 	}
 	return revision;
+#endif
 }
 
 void platform_request_boot(void)