diff --git a/.github/workflows/build_python.yml b/.github/workflows/build_python.yml
index 4f18777f..8827f62d 100644
--- a/.github/workflows/build_python.yml
+++ b/.github/workflows/build_python.yml
@@ -9,7 +9,7 @@ on:
       platforms:
         required: true
         type: string
-        default: "linux-x86_64,linux-aarch64,linux-i386,linux-arm,linux-riscv64,linux-loongarch64,linux-s390x,macos,windows,cosmo,freebsd13-x86_64,freebsd14-x86_64,freebsd15-x86_64,solaris11-x86_64"
+        default: "linux-x86_64,linux-aarch64,linux-i386,linux-arm,linux-riscv64,linux-loongarch64,linux-s390x,linux-mips64el,macos,windows,cosmo,freebsd13-x86_64,freebsd14-x86_64,freebsd15-x86_64,solaris11-x86_64"
       buildsystem_branch:
         required: false
         type: string
@@ -52,8 +52,8 @@ env:
   DEBUG_CI: ${{ inputs.debug }}
   VERBOSE_CI: ${{ inputs.verbose }}
   PORTABLE_PYTHON_BUILDSYSTEM_BRANCH: ${{ inputs.buildsystem_branch || 'portable-python' }}
-  image_map: '{"x86_64": "amd64/ubuntu:18.04", "i386": "i386/ubuntu:18.04", "aarch64": "arm64v8/ubuntu:18.04", "arm": "arm32v7/debian:bullseye", "riscv64": "riscv64/debian:sid", "loongarch64": "loongarch64/debian:sid", "s390x": "s390x/debian:bullseye"}'
-  platform_map: '{"x86_64": "linux/amd64", "i386": "linux/386", "aarch64": "linux/arm64/v8", "arm": "linux/arm/v7", "riscv64": "linux/riscv64", "loongarch64": "linux/loong64", "s390x": "linux/s390x"}'
+  image_map: '{"x86_64": "amd64/ubuntu:18.04", "i386": "i386/ubuntu:18.04", "aarch64": "arm64v8/ubuntu:18.04", "arm": "arm32v7/debian:bullseye", "riscv64": "riscv64/debian:sid", "loongarch64": "loongarch64/debian:sid", "s390x": "s390x/debian:bullseye", "mips64el": "mips64le/debian:bullseye"}'
+  platform_map: '{"x86_64": "linux/amd64", "i386": "linux/386", "aarch64": "linux/arm64/v8", "arm": "linux/arm/v7", "riscv64": "linux/riscv64", "loongarch64": "linux/loong64", "s390x": "linux/s390x", "mips64el": "linux/mips64le"}'
   freebsd_release_map: '{"15": "15.0", "14": "14.0", "13": "13.2"}'
   solaris_release_map: '{"11": "11.4"}'
 
@@ -65,7 +65,7 @@ jobs:
     strategy:
       fail-fast: false
       matrix:
-        arch: [x86_64, i386, aarch64, arm, riscv64, s390x, loongarch64]
+        arch: [x86_64, i386, aarch64, arm, riscv64, s390x, loongarch64, mips64el]
         distribution: [full, headless]
         exclude:
           - arch: ${{ !contains(inputs.platforms, 'linux-x86_64') && 'x86_64' || '' }}
@@ -75,6 +75,7 @@ jobs:
           - arch: ${{ !contains(inputs.platforms, 'linux-riscv64') && 'riscv64' || '' }}
           - arch: ${{ !contains(inputs.platforms, 'linux-loongarch64') && 'loongarch64' || '' }}
           - arch: ${{ !contains(inputs.platforms, 'linux-s390x') && 's390x' || '' }}
+          - arch: ${{ !contains(inputs.platforms, 'linux-mips64el') && 'mips64el' || '' }}
 
     steps:
       - name: Parse image
diff --git a/.github/workflows/build_python_on_branch.yml b/.github/workflows/build_python_on_branch.yml
index 9811d663..97c53af9 100644
--- a/.github/workflows/build_python_on_branch.yml
+++ b/.github/workflows/build_python_on_branch.yml
@@ -35,7 +35,7 @@ jobs:
       run_tests: ${{ inputs.run_tests || false }}
       debug: ${{ inputs.debug || false }}
       verbose: ${{ inputs.verbose || false }}
-      platforms: "linux-x86_64,linux-aarch64,linux-i386,linux-arm,linux-riscv64,linux-loongarch64,linux-s390x,macos,windows,cosmo,freebsd13-x86_64,freebsd14-x86_64,freebsd15-x86_64,solaris11-x86_64"
+      platforms: "linux-x86_64,linux-aarch64,linux-i386,linux-arm,linux-riscv64,linux-loongarch64,linux-s390x,linux-mips64el,macos,windows,cosmo,freebsd13-x86_64,freebsd14-x86_64,freebsd15-x86_64,solaris11-x86_64"
       buildsystem_branch: ${{ inputs.buildsystem_branch || 'portable-python' }}
 
   graalpy:
diff --git a/.github/workflows/release_python.yml b/.github/workflows/release_python.yml
index 928d153c..6491084d 100644
--- a/.github/workflows/release_python.yml
+++ b/.github/workflows/release_python.yml
@@ -26,7 +26,7 @@ jobs:
     uses: ./.github/workflows/build_python.yml
     with:
       python_version: ${{ inputs.python_version }}
-      platforms: "linux-x86_64,linux-aarch64,linux-i386,linux-arm,linux-riscv64,linux-s390x,linux-loongarch64,macos,windows,cosmo,freebsd13-x86_64,freebsd14-x86_64,freebsd15-x86_64,solaris11-x86_64"
+      platforms: "linux-x86_64,linux-aarch64,linux-i386,linux-arm,linux-riscv64,linux-s390x,linux-loongarch64,linux-mips64el,macos,windows,cosmo,freebsd13-x86_64,freebsd14-x86_64,freebsd15-x86_64,solaris11-x86_64"
 
   publish:
     name: Publish CPython ${{ inputs.python_version }}
diff --git a/scripts/build_linux_zig.sh b/scripts/build_linux_zig.sh
index 1047b0ff..6e427649 100755
--- a/scripts/build_linux_zig.sh
+++ b/scripts/build_linux_zig.sh
@@ -49,6 +49,10 @@ case "$ARCH" in
     sudo apt -y install libc6-s390x-cross
     sudo ln -s /usr/s390x-linux-gnu/lib/ld64.so.1 /lib/ld64.so.1
     ;;
+  mips64el)
+    sudo apt -y install libc6-mips64el-cross
+    sudo ln -s /usr/mips64el-linux-gnuabi64/lib64/ld.so.1 /lib/ld.so.1
+    ;;
 esac
 sudo pip install https://github.com/mesonbuild/meson/archive/2baae24.zip ninja cmake==3.28.4 --break-system-packages
 if [[ "${ARCH}" == "riscv64" ]]; then
@@ -104,6 +108,8 @@ else
     export ZIG_FLAGS="-target loongarch64-linux-gnu.2.36"
   elif [[ "${ARCH}" == "s390x" ]]; then
     export ZIG_FLAGS="-target s390x-linux-gnu.2.19"
+  elif [[ "${ARCH}" == "mips64el" ]]; then
+    export ZIG_FLAGS="-target mips64el-linux-gnuabi64.2.19"
   else
     export ZIG_FLAGS="-target ${ARCH}-linux-gnu.2.17"
   fi
@@ -143,7 +149,7 @@ if [[ "${ARCH}" == "arm" ]]; then
   ./Configure linux-generic32 no-shared --prefix=${DEPSDIR} --openssldir=${DEPSDIR}
 elif [[ "${ARCH}" == "i386" ]]; then
   CFLAGS="${CFLAGS} -fgnuc-version=0 -D__STDC_NO_ATOMICS__" ./Configure linux-x86 no-shared --prefix=${DEPSDIR} --openssldir=${DEPSDIR}
-elif [[ "${ARCH}" == "riscv64" ]]; then
+elif [[ "${ARCH}" == "riscv64" || "${ARCH}" == "mips64el" ]]; then
   CFLAGS="${CFLAGS} -fgnuc-version=0 -D__STDC_NO_ATOMICS__" ./Configure linux-generic64 no-shared --prefix=${DEPSDIR} --openssldir=${DEPSDIR}
 elif [[ "${ARCH}" == "loongarch64" ]]; then
   ./Configure linux64-loongarch64 no-shared --prefix=${DEPSDIR} --openssldir=${DEPSDIR}
diff --git a/scripts/qemu_mips64le_interpreter b/scripts/qemu_mips64le_interpreter
new file mode 100755
index 00000000..b1ede4e5
--- /dev/null
+++ b/scripts/qemu_mips64le_interpreter
@@ -0,0 +1,4 @@
+#!/bin/bash
+# this interpreter shim is used by cmake to run platform
+# detection programs
+LD_LIBRARY_PATH=/usr/s390x-linux-gnu/lib qemu-mips64el-static "$@"
\ No newline at end of file