diff --git a/src/graph/kg_edge.ts b/src/graph/kg_edge.ts
index b4a54281..d6422ab4 100644
--- a/src/graph/kg_edge.ts
+++ b/src/graph/kg_edge.ts
@@ -25,7 +25,7 @@ export default class KGEdge {
   };
   publications: Set<string>;
   qualifiers: {
-    [qualifier_type_id: string]: string;
+    [qualifier_type_id: string]: string | string[];
   };
   attributes: {
     [attribute_type_id: string]: Set<string> | TrapiAttribute[];
@@ -105,7 +105,7 @@ export default class KGEdge {
     });
   }
 
-  addQualifier(name: string, value: string): void {
+  addQualifier(name: string, value: string | string[]): void {
     this.qualifiers[name] = value;
   }
 
diff --git a/src/inferred_mode/inferred_mode.ts b/src/inferred_mode/inferred_mode.ts
index fde4f8a0..727f8c52 100644
--- a/src/inferred_mode/inferred_mode.ts
+++ b/src/inferred_mode/inferred_mode.ts
@@ -168,7 +168,9 @@ export default class InferredQueryHandler {
       return Object.fromEntries(
         qualifierSetObj.qualifier_set.map(({ qualifier_type_id, qualifier_value }) => [
           qualifier_type_id.replace('biolink:', ''),
-          qualifier_value.replace('biolink:', ''),
+          Array.isArray(qualifier_value)
+            ? qualifier_value.map((string) => string.replace('biolink:', ''))
+            : qualifier_value.replace('biolink:', ''),
         ]),
       ) as CompactQualifiers;
     });
diff --git a/src/query_edge.ts b/src/query_edge.ts
index 476fa527..e380b51c 100644
--- a/src/query_edge.ts
+++ b/src/query_edge.ts
@@ -151,14 +151,25 @@ export default class QEdge {
       return {
         qualifier_set: qualifierSetObj.qualifier_set.map(({ qualifier_type_id, qualifier_value }) => {
           const new_qualifier_values = qualifier_type_id.includes('predicate')
-            ? Array.from(
-                new Set(
-                  biolink
-                    .getDescendantPredicates(utils.removeBioLinkPrefix(qualifier_value))
-                    .map((item) => `biolink:${utils.removeBioLinkPrefix(item)}`),
-                ),
-              )
-            : Array.from(new Set(biolink.getDescendantQualifiers(utils.removeBioLinkPrefix(qualifier_value))));
+            ? Array.isArray(qualifier_value)
+              ? Array.from(
+                  qualifier_value.reduce((set: Set<string>, predicate: string) => {
+                    biolink
+                      .getDescendantPredicates(utils.removeBioLinkPrefix(predicate))
+                      .forEach((item) => set.add(`biolink:${utils.removeBioLinkPrefix(item)}`));
+                    return set;
+                  }, new Set()),
+                )
+              : Array.from(
+                  new Set(
+                    biolink
+                      .getDescendantPredicates(utils.removeBioLinkPrefix(qualifier_value))
+                      .map((item) => `biolink:${utils.removeBioLinkPrefix(item)}`),
+                  ),
+                )
+            : Array.from(
+                new Set(biolink.getDescendantQualifiers(utils.removeBioLinkPrefix(qualifier_value as string))),
+              );
 
           return {
             qualifier_type_id,
@@ -180,7 +191,11 @@ export default class QEdge {
             let newQualifierType = qualifier_type_id;
             let newQualifierValue = qualifier_value;
             if (qualifier_type_id.includes('predicate')) {
-              newQualifierValue = `biolink:${this.getReversedPredicate(qualifier_value.replace('biolink:', ''))}`;
+              if (Array.isArray(qualifier_value)) {
+                newQualifierValue = qualifier_value.map((str) => `biolink:${str.replace('biolink', '')}`);
+              } else {
+                newQualifierValue = `biolink:${qualifier_value.replace('biolink:', '')}`;
+              }
             }
             if (qualifier_type_id.includes('subject')) {
               newQualifierType = qualifier_type_id.replace('subject', 'object');
@@ -204,7 +219,9 @@ export default class QEdge {
       return Object.fromEntries(
         qualifierSetObj.qualifier_set.map(({ qualifier_type_id, qualifier_value }) => [
           qualifier_type_id.replace('biolink:', ''),
-          qualifier_value.replace('biolink:', ''),
+          Array.isArray(qualifier_value)
+            ? qualifier_value.map((string) => string.replace('biolink:', ''))
+            : qualifier_value.replace('biolink:', ''),
         ]),
       );
     });
diff --git a/src/types.ts b/src/types.ts
index 367271c9..5e02e4ad 100644
--- a/src/types.ts
+++ b/src/types.ts
@@ -93,7 +93,7 @@ export interface TrapiAttribute {
 
 export interface TrapiQualifier {
   qualifier_type_id: string;
-  qualifier_value: string;
+  qualifier_value: string | string[];
 }
 
 export interface TrapiQualifierConstraint {
diff --git a/src/utils.ts b/src/utils.ts
index bd41f14d..1d999058 100644
--- a/src/utils.ts
+++ b/src/utils.ts
@@ -9,11 +9,12 @@ export function getUnique<Type>(input: Type[]): Type[] {
   return Array.from(new Set(input));
 }
 
-export function removeBioLinkPrefix(input: string): string {
-  if (input && input.startsWith('biolink:')) {
-    return input.slice(8);
+export function removeBioLinkPrefix<T extends string | string[]>(input: T): T {
+  if (Array.isArray(input)) {
+    return input.map((str: string) => str.replace('biolink:', '')) as T;
+  } else {
+    return input.replace('biolink:', '') as T;
   }
-  return input;
 }
 
 // This gets the intersection of two sets.