diff --git a/recipes/bcbio-gff/meta.yaml b/recipes/bcbio-gff/meta.yaml
index c20f469208e11..90f1c2105a763 100644
--- a/recipes/bcbio-gff/meta.yaml
+++ b/recipes/bcbio-gff/meta.yaml
@@ -21,7 +21,7 @@ requirements:
   run:
     - python
     - six
-    - biopython <1.81
+    - biopython
     - bx-python
 
 test: