You signed in with another tab or window. Reload to refresh your session.You signed out in another tab or window. Reload to refresh your session.You switched accounts on another tab or window. Reload to refresh your session.Dismiss alert
I have a question. I know that I can use the create_custom_window to provide a list of "parent/regulator" genes, such as TF, to reduce the calculation time for big datasets. I was wondering whether there is a way also to answer this other question: I have a list of genes, and I am interested to get a ranked list of genes that best predict the response of the genes in this set. In other words, pre-filter for child column/regulated genes instead of parents/regulators.
Biologically, I am interested to see if I can find genes that are not necessarily TFs but are regulating a set of well-known genes that play an active role under a treatment.
I tried to modify create_custom_window function and a few others but it seems that I am breaking some internal variables and my results are either "wrong" compared to the example provided in this repo or the program crashes.
Thanks a lot.
Best,
Armin
The text was updated successfully, but these errors were encountered:
Hi,
I have a question. I know that I can use the create_custom_window to provide a list of "parent/regulator" genes, such as TF, to reduce the calculation time for big datasets. I was wondering whether there is a way also to answer this other question: I have a list of genes, and I am interested to get a ranked list of genes that best predict the response of the genes in this set. In other words, pre-filter for child column/regulated genes instead of parents/regulators.
Biologically, I am interested to see if I can find genes that are not necessarily TFs but are regulating a set of well-known genes that play an active role under a treatment.
I tried to modify create_custom_window function and a few others but it seems that I am breaking some internal variables and my results are either "wrong" compared to the example provided in this repo or the program crashes.
Thanks a lot.
Best,
Armin
The text was updated successfully, but these errors were encountered: