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This is just to increase my understanding on the resistance genes from CARD database.
I have downloaded the latest RGI 6.0.3 and I have run RGI bwt as I have the wastewater data from Illumina. I am getting 4500 ARGs as an output for each sample.
When I did the co-occurance analysis of bacterial taxa found from Kraken2, and ARG genes from RGI, I am getting 2.5M correlations of bacteria and ARG based on spearman rank correlation. Even though if I filter the correlation data based on correlation >0.9 and p value <0.01, 2500000 significant correlations remain.
I want to know is there any way to reduce the ARG based on some criteria or only focus on significant genes.
The text was updated successfully, but these errors were encountered:
Dear developers,
This is just to increase my understanding on the resistance genes from CARD database.
I have downloaded the latest RGI 6.0.3 and I have run RGI bwt as I have the wastewater data from Illumina. I am getting 4500 ARGs as an output for each sample.
When I did the co-occurance analysis of bacterial taxa found from Kraken2, and ARG genes from RGI, I am getting 2.5M correlations of bacteria and ARG based on spearman rank correlation. Even though if I filter the correlation data based on correlation >0.9 and p value <0.01, 2500000 significant correlations remain.
I want to know is there any way to reduce the ARG based on some criteria or only focus on significant genes.
The text was updated successfully, but these errors were encountered: