diff --git a/bindings/python/Cargo.toml b/bindings/python/Cargo.toml
index b1fac6e2dd8a..38e36ff5acc8 100644
--- a/bindings/python/Cargo.toml
+++ b/bindings/python/Cargo.toml
@@ -158,7 +158,7 @@ futures = "0.3.28"
 opendal = { version = "0.45.1", path = "../../core", features = [
   "layers-blocking",
 ] }
-pyo3 = "0.20.1"
+pyo3 = "0.21.0"
 pyo3-asyncio = { version = "0.20", features = ["tokio-runtime"] }
 tokio = "1"
 bytes = "1.5.0"