The impact of batch effects on the results

[aaaaaaaaaayong]

Hello!
I am working with data from scATAC-seq and scRNA-seq across different batches, with the following characteristics:
scATAC : n_cells × n_regions = 6160 × 264950
scRNA : n_obs × n_vars = 29951 × 18678
celltype: Artery, CA, Capillary, CV, Venous
condition : IZ (treated) and CTRL (control)

When analyzing the data, I observed that:

1. Differences between cells of the same type but from different batches are greater than those between different cell types.
2. Cells receiving the same treatment (IZ or CTRL) appear to cluster together, regardless of their cell type.

It seems that the results are strongly influenced by batch effects.
Could you suggest effective methods or strategies to mitigate batch effects in this context?