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potential workflow for MultiMAP.Integration for cross species analysis #8

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deevdevil88 opened this issue Jul 25, 2022 · 2 comments
Open

potential workflow for MultiMAP.Integration for cross species analysis #8

deevdevil88 opened this issue Jul 25, 2022 · 2 comments

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@deevdevil88
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Hi,
I had a quick question in regards to using MultiMAP for cross species analysis, should I only have the 1:1 orthologues between the two species in each of the AnnData objects, or can i also have unshared features?

Best,
Devika
@ktpolanski
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That's a neat application of MultiMAP!

You're welcome to have unshared features as well, and use those to compute the single-species dataset reductions. The transcriptomics plus ATAC integration in the demo has some number of unique features for each modality.

@deevdevil88
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Great! We will try it with unshared features then. Thanks for getting back to me .
Best,
Devika

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@ktpolanski @deevdevil88