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Confidence Level: 0

+

AUTHORS: PMID:25320081

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Confidence Level: 0

+

AUTHORS: PMID:25320081

+ + + + + + + + + + + + + + + + + + + + + + + + + + +

Confidence Level: 0

+

AUTHORS: PMID:25320081

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Confidence Level: 0

+

AUTHORS: PMID:25320081

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Confidence Level: 0

+

AUTHORS: PMID:25320081

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Confidence Level: 0

+

AUTHORS: PMID:25320081

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Confidence Level: 0

+

AUTHORS: PMID:34428349

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Confidence Level: 0

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AUTHORS: PMID:29987032

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Confidence Level: 0

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Confidence Level: 0

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Confidence Level: 0

+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +

Confidence Level: 0

+ + + + + + + + + + + + + + + + + + + + + + + + + + @@ -561069,7 +561516,6 @@ - @@ -562616,7 +563062,6 @@ - @@ -563295,9 +563740,13 @@ + + + + @@ -563563,6 +564012,8 @@ + + @@ -563893,6 +564344,10 @@ + + + + @@ -567442,7 +567897,6 @@ - @@ -567720,7 +568174,6 @@ - @@ -569067,7 +569520,6 @@ - @@ -569519,10 +569971,8 @@ - - @@ -569930,15 +570380,7 @@ - - - - - - - - - + @@ -569972,13 +570414,13 @@ - + - + @@ -570002,7 +570444,7 @@ - + @@ -570099,13 +570541,13 @@ - + - + @@ -570266,7 +570708,7 @@ - + @@ -570329,7 +570771,7 @@ - + @@ -570409,7 +570851,7 @@ - + @@ -570583,7 +571025,7 @@ - + @@ -570622,21 +571064,16 @@ - + - - - - - + - @@ -570680,7 +571117,7 @@ - + @@ -570707,7 +571144,7 @@ - + @@ -570789,9 +571226,11 @@ + + - + @@ -570890,7 +571329,7 @@ - + @@ -570930,7 +571369,7 @@ - + @@ -571059,7 +571498,7 @@ - + @@ -571082,7 +571521,7 @@ - + @@ -571160,7 +571599,7 @@ - + @@ -571223,7 +571662,7 @@ - + @@ -571237,7 +571676,7 @@ - + @@ -571266,12 +571705,12 @@ - + - + @@ -571291,7 +571730,7 @@ - + @@ -571321,7 +571760,7 @@ - + @@ -571567,7 +572006,7 @@ - + @@ -571577,10 +572016,9 @@ - + - @@ -571738,7 +572176,7 @@ - + @@ -571762,7 +572200,7 @@ - + @@ -571814,7 +572252,7 @@ - + @@ -571838,12 +572276,15 @@ + + + - + @@ -571870,7 +572311,7 @@ - + @@ -571945,7 +572386,7 @@ - + @@ -571973,7 +572414,7 @@ - + @@ -572012,7 +572453,7 @@ - + @@ -572024,7 +572465,7 @@ - + @@ -572138,7 +572579,7 @@ - + @@ -572218,7 +572659,7 @@ - + @@ -572256,7 +572697,7 @@ - + @@ -572270,7 +572711,7 @@ - + @@ -572365,10 +572806,9 @@ - - + @@ -572376,9 +572816,10 @@ + - + @@ -572402,7 +572843,7 @@ - + @@ -572537,7 +572978,7 @@ - + @@ -572579,7 +573020,7 @@ - + @@ -572675,7 +573116,7 @@ - + @@ -572689,7 +573130,7 @@ - + @@ -572711,7 +573152,7 @@ - + @@ -572722,20 +573163,20 @@ - + - + - + @@ -573972,7 +574413,6 @@ - @@ -574363,7 +574803,6 @@ - @@ -574431,7 +574870,6 @@ - @@ -574453,7 +574891,6 @@ - @@ -574564,8 +575001,6 @@ - - @@ -574732,7 +575167,6 @@ - @@ -574753,15 +575187,8 @@ - - - - - - - @@ -575393,7 +575820,6 @@ - @@ -575616,8 +576042,6 @@ - - @@ -575882,6 +576306,7 @@ + @@ -576235,7 +576660,6 @@ - @@ -576857,14 +577281,65 @@ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + - + - + @@ -576902,7 +577377,7 @@ - + @@ -576911,8 +577386,6 @@ - - @@ -576923,10 +577396,9 @@ - - + @@ -577008,7 +577480,7 @@ - + @@ -577016,7 +577488,7 @@ - + @@ -577030,12 +577502,12 @@ - + - + @@ -577091,7 +577563,7 @@ - + @@ -577105,7 +577577,7 @@ - + @@ -577113,13 +577585,13 @@ - + - + @@ -577134,13 +577606,13 @@ - + - + @@ -577178,7 +577650,7 @@ - + @@ -577233,7 +577705,7 @@ - + @@ -577395,7 +577867,7 @@ - + diff --git a/model/Rat-GEM.yml b/model/Rat-GEM.yml index d5bbbe6..300a4bd 100644 --- a/model/Rat-GEM.yml +++ b/model/Rat-GEM.yml @@ -3,8 +3,8 @@ - metaData: short_name: "Rat-GEM" full_name: "" - version: "" - date: "2023-10-01" + version: "1.8.0" + date: "2023-12-10" taxonomy: "" github: "" description: "" @@ -10257,13 +10257,6 @@ - formula: "C16H20NO9" - charge: -1 - inchis: "" - - !!omap - - id: "MAM00926c" - - name: "4-(2-aminophenyl)-2,4-dioxobutanoate" - - compartment: "c" - - formula: "C10H8NO4" - - charge: -1 - - inchis: "" - !!omap - id: "MAM00927c" - name: "4-(methylnitrosamino)-1-(1-oxido-3-pyridinyl)-1-butanone" @@ -19994,13 +19987,6 @@ - formula: "C19H19N7O6" - charge: -2 - inchis: "" - - !!omap - - id: "MAM01701c" - - name: "dihydrolipoamide" - - compartment: "c" - - formula: "C8H17NOS2" - - charge: 0 - - inchis: "" - !!omap - id: "MAM01701m" - name: "dihydrolipoamide" @@ -21835,6 +21821,13 @@ - formula: "C17H19N4O9P" - charge: -2 - inchis: "" + - !!omap + - id: "MAM01828x" + - name: "FMN" + - compartment: "x" + - formula: "C17H19N4O9P" + - charge: -2 + - inchis: "" - !!omap - id: "MAM01829g" - name: "fn2m2masn" @@ -25587,6 +25580,20 @@ - formula: "C6H11O2" - charge: -1 - inchis: "" + - !!omap + - id: "MAM02120x" + - name: "hexanoic acid" + - compartment: "x" + - formula: "C6H11O2" + - charge: -1 + - inchis: "" + - !!omap + - id: "MAM02120m" + - name: "hexanoic acid" + - compartment: "m" + - formula: "C6H11O2" + - charge: -1 + - inchis: "" - !!omap - id: "MAM02121c" - name: "hexanoyl-[ACP]" @@ -28569,20 +28576,6 @@ - formula: "C20H31O5" - charge: -1 - inchis: "" - - !!omap - - id: "MAM02397c" - - name: "lipoyl-[ACP]" - - compartment: "c" - - formula: "C19H33N2O8PRS3" - - charge: -1 - - inchis: "" - - !!omap - - id: "MAM02398c" - - name: "lipoyl-AMP" - - compartment: "c" - - formula: "C18H25N5O8PS2" - - charge: -1 - - inchis: "" - !!omap - id: "MAM02399c" - name: "lipoyllysine" @@ -46573,13 +46566,6 @@ - formula: "C20H35O2" - charge: -1 - inchis: "" - - !!omap - - id: "MAM03684c" - - name: "Hexanoate (N-C6:0)" - - compartment: "c" - - formula: "C6H11O2" - - charge: -1 - - inchis: "" - !!omap - id: "MAM03976c" - name: "Cia-5,8, Tetradecadienoic Acid" @@ -47574,20 +47560,6 @@ - formula: "C9H9O3" - charge: -1 - inchis: "" - - !!omap - - id: "MAM03684m" - - name: "Hexanoate (N-C6:0)" - - compartment: "m" - - formula: "C6H11O2" - - charge: -1 - - inchis: "" - - !!omap - - id: "MAM03684x" - - name: "Hexanoate (N-C6:0)" - - compartment: "x" - - formula: "C6H11O2" - - charge: -1 - - inchis: "" - !!omap - id: "MAM02169e" - name: "indoleacetate" @@ -51319,13 +51291,6 @@ - formula: "C23H48N2O5PRCO" - charge: 0 - inchis: "" - - !!omap - - id: "MAM03684e" - - name: "Hexanoate (N-C6:0)" - - compartment: "e" - - formula: "C6H11O2" - - charge: -1 - - inchis: "" - !!omap - id: "MAM01954c" - name: "glcnac-alpha-1,4-core 1" @@ -58284,6 +58249,13 @@ - formula: "C20H33O3" - charge: 0 - inchis: "" + - !!omap + - id: "MAM20019c" + - name: "FMNH2" + - compartment: "c" + - formula: "C17H21N4O9P" + - charge: -2 + - inchis: "" - !!omap - id: "MAM20019r" - name: "FMNH2" @@ -58292,10 +58264,10 @@ - charge: -2 - inchis: "" - !!omap - - id: "MAM20020r" + - id: "MAM01828r" - name: "FMN" - compartment: "r" - - formula: "C17H18N4O9P" + - formula: "C17H19N4O9P" - charge: -2 - inchis: "" - !!omap @@ -58320,17 +58292,17 @@ - charge: 0 - inchis: "" - !!omap - - id: "MAM20022i" + - id: "MAM20019i" - name: "FMNH2" - compartment: "i" - formula: "C17H21N4O9P" - charge: -2 - inchis: "" - !!omap - - id: "MAM20023i" + - id: "MAM01828i" - name: "FMN" - compartment: "i" - - formula: "C17H18N4O9P" + - formula: "C17H19N4O9P" - charge: -2 - inchis: "" - !!omap @@ -62016,7 +61988,7 @@ - MAM02774m: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acad10 or Acad11 or Acad8 or Acad9 or Acadm or Acads or Acadsb" + - gene_reaction_rule: "Acad11 or Acad8 or Acad9 or Acadm or Acads or Acadsb" - rxnNotes: "" - eccodes: "1.3.99.3;1.3.8.7" - references: "PMID:10502673;PMID:3597357;PMID:4062874" @@ -62374,7 +62346,7 @@ - MAM01803m: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acad10 or Acad11 or Acad8 or Acad9 or Acadm or Acads or Acadsb" + - gene_reaction_rule: "Acad11 or Acad8 or Acad9 or Acadm or Acads or Acadsb" - rxnNotes: "" - eccodes: "1.3.99.3" - references: "PMID:13295225;PMID:3597357" @@ -65475,9 +65447,9 @@ - name: "(S)-dihydroorotate:NAD+ oxidoreductase" - metabolites: !!omap - MAM00180c: -1 + - MAM01828c: -1 - MAM02659c: 1 - - MAM03102m: 1 - - MAM03103m: -1 + - MAM20019c: 1 - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "Dhodh" @@ -71326,10 +71298,10 @@ - id: "MAR08433" - name: "" - metabolites: !!omap + - MAM00209c: -1 - MAM01596m: 1 - MAM01986m: -1 - MAM02039m: -1 - - MAM02393m: -1 - MAM02878m: 1 - lower_bound: 0 - upper_bound: 1000 @@ -71344,8 +71316,8 @@ - id: "MAR08434" - name: "" - metabolites: !!omap + - MAM00208c: 1 - MAM01045m: 1 - - MAM01701m: 1 - MAM02039m: 1 - MAM02578m: 1 - MAM02878m: -1 @@ -71772,25 +71744,6 @@ - subsystem: - "Histidine metabolism" - confidence_score: 0 - - !!omap - - id: "MAR04239" - - name: "2-oxoadipate dehydrogenase complex" - - metabolites: !!omap - - MAM00670m: -1 - - MAM01596m: 1 - - MAM01597m: -1 - - MAM01977m: 1 - - MAM02552m: -1 - - MAM02553m: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Dld and Dlst and Ogdh" - - rxnNotes: "" - - eccodes: "1.2.4.2" - - references: "PMID:10676873" - - subsystem: - - "Lysine metabolism" - - confidence_score: 0 - !!omap - id: "MAR04241" - name: "S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase" @@ -71874,10 +71827,10 @@ - MAM02899m: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Dhtkd1 or Ogdh or Ogdhl" + - gene_reaction_rule: "(Dlst and Ogdh) or (Dhtkd1 and Dlst)" - rxnNotes: "" - eccodes: "1.2.4.2" - - references: "PMID:10676873" + - references: "PMID:28757203;PMID:32160276" - subsystem: - "Lysine metabolism" - confidence_score: 0 @@ -71989,7 +71942,7 @@ - gene_reaction_rule: "Dlst" - rxnNotes: "" - eccodes: "2.3.1.61" - - references: "PMID:9620315" + - references: "PMID:9620315;PMID:28757203;PMID:32160276" - subsystem: - "Lysine metabolism" - confidence_score: 0 @@ -72477,39 +72430,6 @@ - subsystem: - "Tryptophan metabolism" - confidence_score: 0 - - !!omap - - id: "MAR08564" - - name: "" - - metabolites: !!omap - - MAM00926c: 1 - - MAM01306c: -1 - - MAM01974c: 1 - - MAM02319c: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Aadat or Kyat1 or Kyat3" - - rxnNotes: "" - - eccodes: "2.6.1.7" - - references: "" - - subsystem: - - "Tryptophan metabolism" - - confidence_score: 0 - - !!omap - - id: "MAR08565" - - name: "" - - metabolites: !!omap - - MAM00926c: -1 - - MAM00990c: 1 - - MAM02040c: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "" - - subsystem: - - "Tryptophan metabolism" - - confidence_score: 0 - !!omap - id: "MAR08566" - name: "" @@ -73458,25 +73378,6 @@ - subsystem: - "Phenylalanine, tyrosine and tryptophan biosynthesis" - confidence_score: 0 - - !!omap - - id: "MAR03940" - - name: "L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)" - - metabolites: !!omap - - MAM01698c: 1 - - MAM02040c: 1 - - MAM02630c: -1 - - MAM02724c: -1 - - MAM02978c: -1 - - MAM03101c: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Pah" - - rxnNotes: "" - - eccodes: "1.14.16.1" - - references: "PMID:3298976;PMID:4074362" - - subsystem: - - "Phenylalanine, tyrosine and tryptophan biosynthesis" - - confidence_score: 0 - !!omap - id: "MAR04214" - name: "L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)" @@ -73571,14 +73472,14 @@ - id: "MAR04222" - name: "" - metabolites: !!omap - - MAM00990c: -1 - - MAM01306c: 1 - - MAM01974c: -1 - - MAM02040c: -1 - - MAM02319c: 1 - - lower_bound: -1000 + - MAM00990c: 1 + - MAM01306c: -1 + - MAM01974c: 1 + - MAM02040c: 1 + - MAM02319c: -1 + - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Aadat or Kyat1 or Kyat3" + - gene_reaction_rule: "Kyat1 or Kyat3" - rxnNotes: "" - eccodes: "2.6.1.7" - references: "PMID:10756023;PMID:10756023" @@ -77261,19 +77162,14 @@ - id: "MAR08771" - name: "" - metabolites: !!omap - - MAM01285c: 1 - - MAM01371c: -1 - MAM02026c: -1 - MAM02026m: 1 - - MAM02039c: 1 - - MAM02040c: -1 - - MAM02751c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "" + - gene_reaction_rule: "Slc25a39 or Slc25a40" - rxnNotes: "" - eccodes: "" - - references: "" + - references: "PMID:25637873;PMID:34707288;PMID:35513392" - subsystem: - "Transport reactions" - confidence_score: 0 @@ -84367,10 +84263,10 @@ - MAM02984m: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Dhtkd1 or Ogdh or Ogdhl" + - gene_reaction_rule: "Dhtkd1 or Ogdh" - rxnNotes: "" - eccodes: "1.2.4.2" - - references: "PMID:10676873;PMID:3207422" + - references: "PMID:10676873;PMID:3207422;PMID:32160276" - subsystem: - "Tricarboxylic acid cycle and glyoxylate/dicarboxylate metabolism" - confidence_score: 0 @@ -84498,10 +84394,10 @@ - MAM02984m: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Dhtkd1 or Ogdh or Ogdhl" + - gene_reaction_rule: "Dhtkd1 or Ogdh" - rxnNotes: "" - eccodes: "1.2.4.2" - - references: "PMID:10676873" + - references: "PMID:10676873;PMID:32160276" - subsystem: - "Tricarboxylic acid cycle and glyoxylate/dicarboxylate metabolism" - confidence_score: 0 @@ -84518,7 +84414,7 @@ - gene_reaction_rule: "Dlst" - rxnNotes: "" - eccodes: "2.3.1.61" - - references: "PMID:8076640;PMID:9620315" + - references: "PMID:8076640;PMID:9620315;PMID:32160276" - subsystem: - "Tricarboxylic acid cycle and glyoxylate/dicarboxylate metabolism" - confidence_score: 0 @@ -90579,83 +90475,6 @@ - subsystem: - "Lipoic acid metabolism" - confidence_score: 0 - - !!omap - - id: "MAR06398" - - name: "" - - metabolites: !!omap - - MAM01371c: -1 - - MAM02039c: -1 - - MAM02394c: -1 - - MAM02398c: 1 - - MAM02759c: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Lipt1" - - rxnNotes: "" - - eccodes: "2.7.7.63" - - references: "PMID:10103005" - - subsystem: - - "Lipoic acid metabolism" - - confidence_score: 0 - - !!omap - - id: "MAR06399" - - name: "" - - metabolites: !!omap - - MAM00209c: 1 - - MAM01334c: 1 - - MAM01350c: -1 - - MAM02039c: 1 - - MAM02398c: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Lipt1" - - rxnNotes: "" - - eccodes: "2.7.7.63" - - references: "" - - subsystem: - - "Lipoic acid metabolism" - - confidence_score: 0 - - !!omap - - id: "MAR06400" - - name: "" - - metabolites: !!omap - - MAM01098c: 2 - - MAM02039c: -5 - - MAM02040c: 6 - - MAM02397c: 1 - - MAM02471c: 2 - - MAM02554c: 7 - - MAM02555c: -7 - - MAM02643c: -1 - - MAM02681c: 2 - - MAM02682c: -2 - - MAM02877c: -2 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Lias or Lipt2" - - rxnNotes: "" - - eccodes: "2.8.1.8;2.3.1.181" - - references: "" - - subsystem: - - "Lipoic acid metabolism" - - confidence_score: 0 - - !!omap - - id: "MAR06401" - - name: "lipoyl-[acp]:protein N6-lipoyltransferase" - - metabolites: !!omap - - MAM00184c: 1 - - MAM00209c: 1 - - MAM01350c: -1 - - MAM02397c: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Lipt2" - - rxnNotes: "" - - eccodes: "2.3.1.181" - - references: "" - - subsystem: - - "Lipoic acid metabolism" - - confidence_score: 0 - !!omap - id: "MAR06402" - name: "octanoyl-[acp]:protein N6-octanoyltransferase" @@ -95216,7 +95035,7 @@ - MAM02538c: -1 - lower_bound: -1000 - upper_bound: 1000 - - gene_reaction_rule: "Dgat2l6 or Esco1 or Esco2 or Glyatl3 or Hhat or Lclat1 or Lipt1 or Lpcat1 or Lpcat2 or Lpcat3 or Lpcat4 or Lpgat1 or Mboat1 or Mboat2 or Mboat4 or Mboat7 or Naa10 or Naa20 or Naa40 or Naa50 or Naa60 or Naa80 or Nat10 or Nat14 or Nat8 or Nat9 or Pla2g15 or Pnpla3 or Porcn or Satl1 or Sh3glb1 or Ykt6 or Zdhhc1 or Zdhhc11 or Zdhhc12 or Zdhhc13 or Zdhhc14 or Zdhhc15 or Zdhhc16 or Zdhhc17 or Zdhhc18 or Zdhhc19 or Zdhhc2 or Zdhhc20 or Zdhhc21 or Zdhhc22 or Zdhhc23 or Zdhhc24 or Zdhhc3 or Zdhhc4 or Zdhhc5 or Zdhhc6 or Zdhhc7 or Zdhhc8 or Zdhhc9" + - gene_reaction_rule: "Dgat2l6 or Esco1 or Esco2 or Glyatl3 or Hhat or Lclat1 or Lpcat1 or Lpcat2 or Lpcat3 or Lpcat4 or Lpgat1 or Mboat1 or Mboat2 or Mboat4 or Mboat7 or Naa10 or Naa20 or Naa40 or Naa50 or Naa60 or Naa80 or Nat10 or Nat14 or Nat8 or Nat9 or Pla2g15 or Pnpla3 or Porcn or Satl1 or Sh3glb1 or Ykt6 or Zdhhc1 or Zdhhc11 or Zdhhc12 or Zdhhc13 or Zdhhc14 or Zdhhc15 or Zdhhc16 or Zdhhc17 or Zdhhc18 or Zdhhc19 or Zdhhc2 or Zdhhc20 or Zdhhc21 or Zdhhc22 or Zdhhc23 or Zdhhc24 or Zdhhc3 or Zdhhc4 or Zdhhc5 or Zdhhc6 or Zdhhc7 or Zdhhc8 or Zdhhc9" - rxnNotes: "" - eccodes: "2.3.1.-" - references: "PMID:9870464;PMID:9755286;PMID:10833489;PMID:9526099" @@ -95234,7 +95053,7 @@ - MAM02538n: -1 - lower_bound: -1000 - upper_bound: 1000 - - gene_reaction_rule: "Dgat2l6 or Esco1 or Esco2 or Glyatl3 or Hhat or Lclat1 or Lipt1 or Lpcat1 or Lpcat2 or Lpcat3 or Lpcat4 or Lpgat1 or Mboat1 or Mboat2 or Mboat4 or Mboat7 or Naa10 or Naa20 or Naa40 or Naa50 or Naa60 or Naa80 or Nat10 or Nat14 or Nat8 or Nat9 or Pla2g15 or Pnpla3 or Porcn or Satl1 or Sh3glb1 or Ykt6 or Zdhhc1 or Zdhhc11 or Zdhhc12 or Zdhhc13 or Zdhhc14 or Zdhhc15 or Zdhhc16 or Zdhhc17 or Zdhhc18 or Zdhhc19 or Zdhhc2 or Zdhhc20 or Zdhhc21 or Zdhhc22 or Zdhhc23 or Zdhhc24 or Zdhhc3 or Zdhhc4 or Zdhhc5 or Zdhhc6 or Zdhhc7 or Zdhhc8 or Zdhhc9" + - gene_reaction_rule: "Dgat2l6 or Esco1 or Esco2 or Glyatl3 or Hhat or Lclat1 or Lpcat1 or Lpcat2 or Lpcat3 or Lpcat4 or Lpgat1 or Mboat1 or Mboat2 or Mboat4 or Mboat7 or Naa10 or Naa20 or Naa40 or Naa50 or Naa60 or Naa80 or Nat10 or Nat14 or Nat8 or Nat9 or Pla2g15 or Pnpla3 or Porcn or Satl1 or Sh3glb1 or Ykt6 or Zdhhc1 or Zdhhc11 or Zdhhc12 or Zdhhc13 or Zdhhc14 or Zdhhc15 or Zdhhc16 or Zdhhc17 or Zdhhc18 or Zdhhc19 or Zdhhc2 or Zdhhc20 or Zdhhc21 or Zdhhc22 or Zdhhc23 or Zdhhc24 or Zdhhc3 or Zdhhc4 or Zdhhc5 or Zdhhc6 or Zdhhc7 or Zdhhc8 or Zdhhc9" - rxnNotes: "" - eccodes: "2.3.1.-" - references: "PMID:9870464;PMID:9755286;PMID:10833489;PMID:9526099" @@ -98447,7 +98266,7 @@ - confidence_score: 0 - !!omap - id: "MAR00154" - - name: "" + - name: "Propanoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -98456,7 +98275,7 @@ - MAM02774c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Acot9 or Baat" + - gene_reaction_rule: "Acot7" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "PMID:11013297;PMID:11013297" @@ -98465,7 +98284,7 @@ - confidence_score: 0 - !!omap - id: "MAR00189" - - name: "" + - name: "Lauroyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -98474,7 +98293,7 @@ - MAM02345c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98483,7 +98302,7 @@ - confidence_score: 0 - !!omap - id: "MAR00193" - - name: "" + - name: "Tridecanoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -98492,7 +98311,7 @@ - MAM03051c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98501,7 +98320,7 @@ - confidence_score: 0 - !!omap - id: "MAR00197" - - name: "" + - name: "Myristoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -98510,7 +98329,7 @@ - MAM02495c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98519,7 +98338,7 @@ - confidence_score: 0 - !!omap - id: "MAR00201" - - name: "" + - name: "(9E)-tetradecenoyl-CoA hydrolase" - metabolites: !!omap - MAM00128c: 1 - MAM00129c: -1 @@ -98528,7 +98347,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98537,7 +98356,7 @@ - confidence_score: 0 - !!omap - id: "MAR00206" - - name: "" + - name: "(7Z)-tetradecenoyl-CoA hydrolase" - metabolites: !!omap - MAM00117c: 1 - MAM00118c: -1 @@ -98546,7 +98365,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98555,7 +98374,7 @@ - confidence_score: 0 - !!omap - id: "MAR00210" - - name: "" + - name: "5-tetradecenoyl-CoA hydrolase" - metabolites: !!omap - MAM01141c: -1 - MAM01597c: 1 @@ -98564,7 +98383,7 @@ - MAM02745c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98573,7 +98392,7 @@ - confidence_score: 0 - !!omap - id: "MAR00214" - - name: "" + - name: "Pentadecanoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -98582,7 +98401,7 @@ - MAM02690c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98591,7 +98410,7 @@ - confidence_score: 0 - !!omap - id: "MAR00223" - - name: "palmitoyl-CoA hydrolase" + - name: "Palmitoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -98600,7 +98419,7 @@ - MAM02678c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98609,7 +98428,7 @@ - confidence_score: 0 - !!omap - id: "MAR00230" - - name: "" + - name: "Palmitoleoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -98618,7 +98437,7 @@ - MAM02677c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98627,7 +98446,7 @@ - confidence_score: 0 - !!omap - id: "MAR00234" - - name: "" + - name: "7-hexadecenoyl-CoA hydrolase" - metabolites: !!omap - MAM01191c: -1 - MAM01197c: 1 @@ -98636,7 +98455,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98645,7 +98464,7 @@ - confidence_score: 0 - !!omap - id: "MAR00238" - - name: "" + - name: "Heptadecanoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -98654,7 +98473,7 @@ - MAM02456c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98663,7 +98482,7 @@ - confidence_score: 0 - !!omap - id: "MAR00242" - - name: "" + - name: "(10Z)-heptadecenoyl-CoA hydrolase" - metabolites: !!omap - MAM00003c: 1 - MAM00004c: -1 @@ -98672,7 +98491,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98681,7 +98500,7 @@ - confidence_score: 0 - !!omap - id: "MAR00246" - - name: "" + - name: "9-heptadecenoyl-CoA hydrolase" - metabolites: !!omap - MAM01237c: -1 - MAM01238c: 1 @@ -98690,7 +98509,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98699,7 +98518,7 @@ - confidence_score: 0 - !!omap - id: "MAR00250" - - name: "stearoyl-CoA hydrolase" + - name: "Stearoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -98708,7 +98527,7 @@ - MAM02941c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "PMID:10092594;PMID:9153233;PMID:16103133;PMID:16940157;PMID:16103133;PMID:16940157;PMID:10578051;PMID:16103133;PMID:16940157;PMID:16103133;PMID:16940157;PMID:16103133;PMID:16940157;PMID:16940157" @@ -98717,7 +98536,7 @@ - confidence_score: 0 - !!omap - id: "MAR00256" - - name: "" + - name: "(13Z)-octadecenoyl-CoA hydrolase" - metabolites: !!omap - MAM00019c: 1 - MAM00020c: -1 @@ -98726,7 +98545,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98735,7 +98554,7 @@ - confidence_score: 0 - !!omap - id: "MAR00260" - - name: "" + - name: "Cis-vaccenoyl-CoA hydrolase" - metabolites: !!omap - MAM01585c: 1 - MAM01586c: -1 @@ -98744,7 +98563,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98753,7 +98572,7 @@ - confidence_score: 0 - !!omap - id: "MAR00264" - - name: "" + - name: "Oleoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -98762,7 +98581,7 @@ - MAM02647c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98771,7 +98590,7 @@ - confidence_score: 0 - !!omap - id: "MAR00268" - - name: "" + - name: "(9E)-octadecenoyl-CoA hydrolase" - metabolites: !!omap - MAM00127c: -1 - MAM01597c: 1 @@ -98780,7 +98599,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98789,7 +98608,7 @@ - confidence_score: 0 - !!omap - id: "MAR00272" - - name: "" + - name: "(7Z)-octadecenoyl-CoA hydrolase" - metabolites: !!omap - MAM00115c: 1 - MAM00116c: -1 @@ -98798,7 +98617,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98807,7 +98626,7 @@ - confidence_score: 0 - !!omap - id: "MAR00276" - - name: "" + - name: "(6Z,9Z)-octadecadienoyl-CoA hydrolase" - metabolites: !!omap - MAM00104c: 1 - MAM00106c: -1 @@ -98816,7 +98635,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98825,7 +98644,7 @@ - confidence_score: 0 - !!omap - id: "MAR00280" - - name: "" + - name: "Nonadecanoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -98834,7 +98653,7 @@ - MAM02613c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot3 or Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98843,7 +98662,7 @@ - confidence_score: 0 - !!omap - id: "MAR00284" - - name: "Icosanoyl-CoA hydrolase" + - name: "Eicosanoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM01771c: 1 @@ -98852,7 +98671,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot3 or Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "PMID:10092594;PMID:9153233;PMID:16103133;PMID:16940157;PMID:16103133;PMID:16940157;PMID:10578051;PMID:16103133;PMID:16940157;PMID:16103133;PMID:16940157;PMID:16103133;PMID:16940157;PMID:16940157" @@ -98861,7 +98680,7 @@ - confidence_score: 0 - !!omap - id: "MAR00290" - - name: "" + - name: "(13Z)-eicosenoyl-CoA hydrolase" - metabolites: !!omap - MAM00017c: 1 - MAM00018c: -1 @@ -98870,7 +98689,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot3 or Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98879,7 +98698,7 @@ - confidence_score: 0 - !!omap - id: "MAR00294" - - name: "" + - name: "(11Z)-eicosenoyl-CoA hydrolase" - metabolites: !!omap - MAM00007c: -1 - MAM01584c: 1 @@ -98888,7 +98707,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot3 or Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98897,7 +98716,7 @@ - confidence_score: 0 - !!omap - id: "MAR00298" - - name: "" + - name: "9-eicosenoyl-CoA hydrolase" - metabolites: !!omap - MAM01235c: 1 - MAM01236c: -1 @@ -98906,7 +98725,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot3 or Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98915,7 +98734,7 @@ - confidence_score: 0 - !!omap - id: "MAR00302" - - name: "" + - name: "(8Z,11Z)-eicosadienoyl-CoA hydrolase" - metabolites: !!omap - MAM00123c: -1 - MAM01207c: 1 @@ -98924,7 +98743,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot3 or Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98933,7 +98752,7 @@ - confidence_score: 0 - !!omap - id: "MAR00306" - - name: "" + - name: "(5Z,8Z,11Z)-eicosatrienoyl-CoA hydrolase" - metabolites: !!omap - MAM00101c: -1 - MAM01597c: 1 @@ -98942,7 +98761,7 @@ - MAM02457c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot3 or Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98951,7 +98770,7 @@ - confidence_score: 0 - !!omap - id: "MAR00310" - - name: "" + - name: "Heneicosanoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -98960,7 +98779,7 @@ - MAM02053c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -98969,7 +98788,7 @@ - confidence_score: 0 - !!omap - id: "MAR00314" - - name: "" + - name: "Docosanoyl-CoA hydrolase" - metabolites: !!omap - MAM01373c: 1 - MAM01597c: 1 @@ -98978,7 +98797,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "PMID:10092594;PMID:9153233;PMID:16103133;PMID:16940157;PMID:16103133;PMID:16940157;PMID:10578051;PMID:16103133;PMID:16940157;PMID:16103133;PMID:16940157;PMID:16103133;PMID:16940157;PMID:16940157" @@ -98987,7 +98806,7 @@ - confidence_score: 0 - !!omap - id: "MAR00320" - - name: "" + - name: "(13Z)-docosenoyl-CoA hydrolase" - metabolites: !!omap - MAM00016c: -1 - MAM01583c: 1 @@ -98996,7 +98815,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99005,7 +98824,7 @@ - confidence_score: 0 - !!omap - id: "MAR00324" - - name: "" + - name: "(11Z)-docosenoyl-CoA hydrolase" - metabolites: !!omap - MAM00006c: -1 - MAM01582c: 1 @@ -99014,7 +98833,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99023,7 +98842,7 @@ - confidence_score: 0 - !!omap - id: "MAR00328" - - name: "" + - name: "Tricosanoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -99032,7 +98851,7 @@ - MAM03047c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99041,7 +98860,7 @@ - confidence_score: 0 - !!omap - id: "MAR00332" - - name: "" + - name: "Tetracosenoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -99050,7 +98869,7 @@ - MAM02971c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "PMID:10092594;PMID:9153233;PMID:16103133;PMID:16940157;PMID:16103133;PMID:16940157;PMID:10578051;PMID:16103133;PMID:16940157;PMID:16103133;PMID:16940157;PMID:16103133;PMID:16940157;PMID:16940157" @@ -99059,7 +98878,7 @@ - confidence_score: 0 - !!omap - id: "MAR00338" - - name: "" + - name: "(15Z)-tetracosenoyl-CoA hydrolase" - metabolites: !!omap - MAM00025c: -1 - MAM01597c: 1 @@ -99068,7 +98887,7 @@ - MAM02564c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99077,7 +98896,7 @@ - confidence_score: 0 - !!omap - id: "MAR00342" - - name: "" + - name: "Hexacosanoyl-CoA hydrolase" - metabolites: !!omap - MAM01432c: 1 - MAM01597c: 1 @@ -99086,7 +98905,7 @@ - MAM02110c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99095,7 +98914,7 @@ - confidence_score: 0 - !!omap - id: "MAR00346" - - name: "" + - name: "Hexacosenoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -99104,7 +98923,7 @@ - MAM03153c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99113,7 +98932,7 @@ - confidence_score: 0 - !!omap - id: "MAR00350" - - name: "" + - name: "Linolenoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -99122,7 +98941,7 @@ - MAM02390c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot3 or Acot7 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99131,7 +98950,7 @@ - confidence_score: 0 - !!omap - id: "MAR00354" - - name: "" + - name: "(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA hydrolase" - metabolites: !!omap - MAM00108c: -1 - MAM01597c: 1 @@ -99140,7 +98959,7 @@ - MAM02939c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot3 or Acot7 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99149,7 +98968,7 @@ - confidence_score: 0 - !!omap - id: "MAR00358" - - name: "" + - name: "(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA hydrolase" - metabolites: !!omap - MAM00125c: -1 - MAM01597c: 1 @@ -99158,7 +98977,7 @@ - MAM02648c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot3 or Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99167,7 +98986,7 @@ - confidence_score: 0 - !!omap - id: "MAR00362" - - name: "(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA hydrolase" + - name: "(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA hydrolase" - metabolites: !!omap - MAM00103c: -1 - MAM01597c: 1 @@ -99176,7 +98995,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot3 or Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99185,7 +99004,7 @@ - confidence_score: 0 - !!omap - id: "MAR00366" - - name: "" + - name: "(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase" - metabolites: !!omap - MAM00121c: -1 - MAM01597c: 1 @@ -99194,7 +99013,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99203,7 +99022,7 @@ - confidence_score: 0 - !!omap - id: "MAR00370" - - name: "" + - name: "(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA hydrolase" - metabolites: !!omap - MAM00134c: -1 - MAM00135c: 1 @@ -99212,7 +99031,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99221,7 +99040,7 @@ - confidence_score: 0 - !!omap - id: "MAR00374" - - name: "" + - name: "(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA hydrolase" - metabolites: !!omap - MAM00113c: -1 - MAM00114c: 1 @@ -99230,7 +99049,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99239,7 +99058,7 @@ - confidence_score: 0 - !!omap - id: "MAR00378" - - name: "" + - name: "(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA hydrolase" - metabolites: !!omap - MAM00095c: -1 - MAM01597c: 1 @@ -99248,7 +99067,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99257,7 +99076,7 @@ - confidence_score: 0 - !!omap - id: "MAR00382" - - name: "" + - name: "(11Z,14Z,17Z)-eicosatrienoyl-CoA hydrolase" - metabolites: !!omap - MAM00010c: 1 - MAM00012c: -1 @@ -99266,7 +99085,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot3 or Acot7 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99275,7 +99094,7 @@ - confidence_score: 0 - !!omap - id: "MAR00386" - - name: "" + - name: "13,16,19-docosatrienoyl-CoA hydrolase" - metabolites: !!omap - MAM00341c: 1 - MAM00343c: -1 @@ -99284,7 +99103,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99293,7 +99112,7 @@ - confidence_score: 0 - !!omap - id: "MAR00390" - - name: "" + - name: "10,13,16,19-docosatetraenoyl-CoA hydrolase" - metabolites: !!omap - MAM00260c: 1 - MAM00262c: -1 @@ -99302,7 +99121,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99311,7 +99130,7 @@ - confidence_score: 0 - !!omap - id: "MAR00394" - - name: "" + - name: "12,15,18,21-tetracosatetraenoyl-CoA hydrolase" - metabolites: !!omap - MAM00315c: 1 - MAM00317c: -1 @@ -99320,7 +99139,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99338,7 +99157,7 @@ - MAM02391c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99347,7 +99166,7 @@ - confidence_score: 0 - !!omap - id: "MAR00402" - - name: "" + - name: "Gamma-linolenoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM01932c: 1 @@ -99356,7 +99175,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99365,7 +99184,7 @@ - confidence_score: 0 - !!omap - id: "MAR00406" - - name: "" + - name: "Dihomo-gamma-linolenoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM01696c: 1 @@ -99374,7 +99193,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99383,7 +99202,7 @@ - confidence_score: 0 - !!omap - id: "MAR00410" - - name: "" + - name: "Arachidonyl-CoA hydrolase" - metabolites: !!omap - MAM01362c: 1 - MAM01364c: -1 @@ -99392,7 +99211,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot13 or Acot3 or Acot7 or Baat or Them4" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99401,7 +99220,7 @@ - confidence_score: 0 - !!omap - id: "MAR00414" - - name: "" + - name: "(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA hydrolase" - metabolites: !!omap - MAM00119c: -1 - MAM01291c: 1 @@ -99410,7 +99229,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99419,7 +99238,7 @@ - confidence_score: 0 - !!omap - id: "MAR00418" - - name: "" + - name: "(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA hydrolase" - metabolites: !!omap - MAM00131c: -1 - MAM00132c: 1 @@ -99428,7 +99247,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99437,7 +99256,7 @@ - confidence_score: 0 - !!omap - id: "MAR00422" - - name: "" + - name: "(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA hydrolase" - metabolites: !!omap - MAM00110c: -1 - MAM00111c: 1 @@ -99446,7 +99265,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99455,7 +99274,7 @@ - confidence_score: 0 - !!omap - id: "MAR00426" - - name: "" + - name: "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA hydrolase" - metabolites: !!omap - MAM00093c: -1 - MAM00094c: 1 @@ -99464,7 +99283,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99473,7 +99292,7 @@ - confidence_score: 0 - !!omap - id: "MAR00430" - - name: "" + - name: "(11Z,14Z)-eicosadienoyl-CoA hydrolase" - metabolites: !!omap - MAM00008c: 1 - MAM00009c: -1 @@ -99482,7 +99301,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot3 or Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99491,7 +99310,7 @@ - confidence_score: 0 - !!omap - id: "MAR00434" - - name: "" + - name: "(13Z,16Z)-docosadienoyl-CoA hydrolase" - metabolites: !!omap - MAM00021c: 1 - MAM00023c: -1 @@ -99500,7 +99319,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99509,7 +99328,7 @@ - confidence_score: 0 - !!omap - id: "MAR00438" - - name: "" + - name: "10,13,16-docosatrienoyl-CoA hydrolase" - metabolites: !!omap - MAM00264c: -1 - MAM00265c: 1 @@ -99518,7 +99337,7 @@ - MAM02040c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot6 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "" @@ -99527,7 +99346,7 @@ - confidence_score: 0 - !!omap - id: "MAR03009" - - name: "" + - name: "Propanoyl-CoA hydrolase (peroxisomal)" - metabolites: !!omap - MAM01597x: 1 - MAM02039x: 1 @@ -99536,7 +99355,7 @@ - MAM02774x: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot4 or Acot8" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "PMID:11013297;PMID:11013297" @@ -99545,7 +99364,7 @@ - confidence_score: 0 - !!omap - id: "MAR03475" - - name: "Acetyl-CoA hydrolase" + - name: "Acetyl-CoA hydrolase (peroxisomal)" - metabolites: !!omap - MAM01252x: 1 - MAM01261x: -1 @@ -99554,7 +99373,7 @@ - MAM02040x: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot8" + - gene_reaction_rule: "Acot4 or Acot8" - rxnNotes: "" - eccodes: "3.1.2.27" - references: "PMID:10092594;PMID:16756494" @@ -121644,24 +121463,6 @@ - subsystem: - "Glycerophospholipid metabolism" - confidence_score: 0 - - !!omap - - id: "MAR00478" - - name: "sn-Glycerol-3-phosphate:NADP+ 2-oxidoreductase" - - metabolites: !!omap - - MAM01690c: -1 - - MAM02039c: -1 - - MAM02554c: 1 - - MAM02555c: -1 - - MAM02914c: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Gpd1" - - rxnNotes: "" - - eccodes: "1.1.1.94" - - references: "PMID:16460752" - - subsystem: - - "Glycerophospholipid metabolism" - - confidence_score: 0 - !!omap - id: "MAR00479" - name: "sn-Glycerol-3-phosphate:NAD+ 2-oxidoreductase" @@ -121676,7 +121477,7 @@ - gene_reaction_rule: "Gpd1 or Gpd1l1" - rxnNotes: "" - eccodes: "1.1.1.8" - - references: "PMID:17045662;PMID:7772607" + - references: "PMID:16460752;PMID:17045662;PMID:7772607" - subsystem: - "Glycerophospholipid metabolism" - confidence_score: 0 @@ -121698,23 +121499,6 @@ - subsystem: - "Glycerophospholipid metabolism" - confidence_score: 0 - - !!omap - - id: "MAR00482" - - name: "sn-Glycerol-3-phosphate:(acceptor) 2-oxidoreductase" - - metabolites: !!omap - - MAM01690c: 1 - - MAM01802c: -1 - - MAM01803c: 1 - - MAM02914c: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Gpd2" - - rxnNotes: "" - - eccodes: "1.1.5.3" - - references: "PMID:11955283;PMID:2115809;PMID:2923620;PMID:3338458;PMID:340460;PMID:8401296;PMID:8549872;PMID:8579375;PMID:9171333;PMID:9244403;PMID:9559543" - - subsystem: - - "Glycerophospholipid metabolism" - - confidence_score: 0 - !!omap - id: "MAR00484" - name: "CDPglycerol phosphoglycerohydrolase" @@ -134728,7 +134512,7 @@ - MAM02774m: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Baat" + - gene_reaction_rule: "Acot1 or Acot2 or Acot3 or Acot4 or Acot6 or Acot7 or Acot9 or Baat" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "PMID:11013297;PMID:11013297" @@ -139902,7 +139686,7 @@ - confidence_score: 0 - !!omap - id: "MAR04665" - - name: "S-Aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming)" + - name: "" - metabolites: !!omap - MAM01044m: -1 - MAM01100m: 1 @@ -139910,10 +139694,10 @@ - MAM02040m: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Amt and Dld and Gcsh and Gldc" + - gene_reaction_rule: "Shmt2" - rxnNotes: "" - eccodes: "2.1.2.10" - - references: "PMID:7916605" + - references: "PMID:11087421" - subsystem: - "Folate metabolism" - confidence_score: 0 @@ -142239,7 +142023,7 @@ - MAM02833c: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Aldh1a1 or Aldh1a2" + - gene_reaction_rule: "Aldh1a1 or Aldh1a2 or Aldh1a3" - rxnNotes: "" - eccodes: "1.2.1.36" - references: "" @@ -173668,28 +173452,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR06406" - - name: "" - - metabolites: !!omap - - MAM01285c: 1 - - MAM01371c: -1 - - MAM02039c: 1 - - MAM02040c: -1 - - MAM02394c: 1 - - MAM02394e: -1 - - MAM02519c: 2 - - MAM02519e: -2 - - MAM02751c: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Slc5a6" - - rxnNotes: "" - - eccodes: "" - - references: "PMID:16415531" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR06424" - name: "" @@ -179116,7 +178878,7 @@ - gene_reaction_rule: "Slc5a6" - rxnNotes: "" - eccodes: "" - - references: "" + - references: "PMID:9516450;PMID:10329687;PMID:15561972" - subsystem: - "Transport reactions" - confidence_score: 0 @@ -180000,21 +179762,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR09019" - - name: "" - - metabolites: !!omap - - MAM01424c: -1 - - MAM01424m: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR09020" - name: "" @@ -181057,23 +180804,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR04843" - - name: "" - - metabolites: !!omap - - MAM01948c: -1 - - MAM01948m: 1 - - MAM02034c: 1 - - MAM02034m: -1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "Aldh1a3 or Aldh3a1 or Aldh3b3" - - rxnNotes: "" - - eccodes: "" - - references: "PMID:11078702" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR04850" - name: "" @@ -181419,23 +181149,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR04940" - - name: "" - - metabolites: !!omap - - MAM02026c: -1 - - MAM02026m: 1 - - MAM02751c: 1 - - MAM02751m: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Slc25a10" - - rxnNotes: "" - - eccodes: "" - - references: "PMID:15845418;PMID:16600197;PMID:9639574" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR04944" - name: "" @@ -183310,40 +183023,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR06391" - - name: "" - - metabolites: !!omap - - MAM01306c: -1 - - MAM01306m: 1 - - MAM02026c: 1 - - MAM02026m: -1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "Slc25a11" - - rxnNotes: "" - - eccodes: "" - - references: "PMID:15845418" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR06408" - - name: "" - - metabolites: !!omap - - MAM01701c: -1 - - MAM01701m: 1 - - MAM02039i: -1 - - MAM02039m: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR06431" - name: "" @@ -185777,16 +185456,16 @@ - id: "MAR03473" - name: "" - metabolites: !!omap + - MAM01285c: -1 + - MAM01285x: 1 - MAM01334c: 1 - MAM01334x: -1 - - MAM01371c: -1 - - MAM01371x: 1 - - lower_bound: 0 + - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "Slc25a17" - rxnNotes: "" - eccodes: "" - - references: "PMID:16756494;PMID:9874197;PMID:12445829;PMID:14598172;PMID:18406340;PMID:9759482" + - references: "PMID:12445829;PMID:16756494;PMID:22185573" - subsystem: - "Transport reactions" - confidence_score: 0 @@ -185987,21 +185666,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR04915" - - name: "" - - metabolites: !!omap - - MAM01597c: -1 - - MAM01597x: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "PMID:14598172" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR04924" - name: "" @@ -186308,36 +185972,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR07771" - - name: "" - - metabolites: !!omap - - MAM02552c: 1 - - MAM02552x: -1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR07775" - - name: "" - - metabolites: !!omap - - MAM02553c: -1 - - MAM02553x: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR07777" - name: "" @@ -186368,81 +186002,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR07782" - - name: "" - - metabolites: !!omap - - MAM01285c: -1 - - MAM01285x: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR07783" - - name: "" - - metabolites: !!omap - - MAM01334c: -1 - - MAM01334x: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR07785" - - name: "" - - metabolites: !!omap - - MAM01371c: -1 - - MAM01371x: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR07788" - - name: "" - - metabolites: !!omap - - MAM01803c: -1 - - MAM01803x: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR07790" - - name: "" - - metabolites: !!omap - - MAM01802c: -1 - - MAM01802x: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR07797" - name: "" @@ -201780,7 +201339,7 @@ - MAM02553m: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "Aldh1b1 or Aldh2 or Aldh4a1" + - gene_reaction_rule: "Aldh1b1 or Aldh2" - rxnNotes: "" - eccodes: "1.5.1.12" - references: "PMID:11306106" @@ -206252,7 +205811,6 @@ - eccodes: "4.99.1.1" - references: "PMID:7983009;PMID:11175906;PMID:11215517;PMID:11853551;PMID:11947230;PMID:1624416;PMID:182145;PMID:2310748;PMID:3196293;PMID:3702737;PMID:406931;PMID:6425295;PMID:7309736;PMID:8818224;PMID:9712849;PMID:9808757" - subsystem: - - "Heme synthesis" - "Porphyrin metabolism" - confidence_score: 0 - !!omap @@ -207271,28 +206829,6 @@ - subsystem: - "Fatty acid oxidation" - confidence_score: 0 - - !!omap - - id: "MAR01483" - - name: "Transport of Lipoate via Sodium Symport" - - metabolites: !!omap - - MAM01285c: 1 - - MAM01371c: -1 - - MAM02039c: 1 - - MAM02040c: -1 - - MAM02394c: 1 - - MAM02394e: -1 - - MAM02519c: 1 - - MAM02519e: -1 - - MAM02751c: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Slc5a6" - - rxnNotes: "" - - eccodes: "" - - references: "PMID:10329687;PMID:10334869;PMID:12646417;PMID:15561972;PMID:9516450" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR01485" - name: "Transport of L-Lactate via Diffusion, Mitochondrial" @@ -208632,7 +208168,7 @@ - eccodes: "1.3.3.4" - references: "PMID:8771201" - subsystem: - - "Heme synthesis" + - "Porphyrin metabolism" - confidence_score: 0 - !!omap - id: "MAR01645" @@ -212258,7 +211794,7 @@ - MAM02941m: -1 - lower_bound: -1000 - upper_bound: 1000 - - gene_reaction_rule: "Acot2 or Acot3 or Acot7" + - gene_reaction_rule: "Acot2 or Acot3 or Acot7 or Them5" - rxnNotes: "" - eccodes: "3.1.2.2" - references: "PMID:10092594;PMID:10578051;PMID:16103133;PMID:16940157;PMID:9153233" @@ -213213,7 +212749,7 @@ - MAM01974m: 1 - MAM02040m: 1 - MAM02319m: -1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "Aadat or Kyat3" - rxnNotes: "" @@ -227021,36 +226557,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR07823" - - name: "Transport of dCTP into Mitochondria" - - metabolites: !!omap - - MAM01645c: -1 - - MAM01645m: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "PMID:16816105;PMID:17403938" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR07926" - - name: "Transport of dGTP into Mitochondria" - - metabolites: !!omap - - MAM01688c: -1 - - MAM01688m: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "PMID:16816105;PMID:17403938" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - !!omap - id: "MAR08111" - name: "Transport of Dihydroxyacetone Phosphate into Cytosol" @@ -227125,12 +226631,12 @@ - metabolites: !!omap - MAM01753c: -1 - MAM01753m: 1 - - lower_bound: 0 + - lower_bound: -1000 - upper_bound: 1000 - - gene_reaction_rule: "" + - gene_reaction_rule: "Slc25a33" - rxnNotes: "" - eccodes: "" - - references: "PMID:16816105;PMID:17403938" + - references: "PMID:25320081" - subsystem: - "Transport reactions" - confidence_score: 0 @@ -230806,24 +230312,6 @@ - subsystem: - "Fatty acid oxidation" - confidence_score: 0 - - !!omap - - id: "MAR09949" - - name: "Acylcoa Hydrolase, Cytosolic" - - metabolites: !!omap - - MAM01597c: 1 - - MAM02039c: 1 - - MAM02040c: -1 - - MAM02122c: -1 - - MAM03684c: 1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "3.1.2.2" - - references: "" - - subsystem: - - "Fatty acid oxidation" - - confidence_score: 0 - !!omap - id: "MAR09950" - name: "Hydrolysis of Tetradecadienoyl Coenzyme A to Cis-5, 8-Tetradecadienoic Acid" @@ -235604,16 +235092,16 @@ - confidence_score: 0 - !!omap - id: "MAR10374" - - name: "Acyl-Coenzyme A Hydrolase, Mitochondrial" + - name: "Hexanoyl-CoA hydrolase, Mitochondrial" - metabolites: !!omap - MAM01597m: 1 - MAM02039m: 1 - MAM02040m: -1 + - MAM02120m: 1 - MAM02122m: -1 - - MAM03684m: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "" + - gene_reaction_rule: "Acot9" - rxnNotes: "" - eccodes: "" - references: "" @@ -235652,16 +235140,16 @@ - confidence_score: 0 - !!omap - id: "MAR10377" - - name: "Acylcoa Hydrolase, Peroxisome" + - name: "Hexanoyl-CoA hydrolase, Peroxisome" - metabolites: !!omap - MAM01597x: 1 - MAM02039x: 1 - MAM02040x: -1 + - MAM02120x: 1 - MAM02122x: -1 - - MAM03684x: 1 - - lower_bound: -1000 + - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "" + - gene_reaction_rule: "Acot8" - rxnNotes: "" - eccodes: "" - references: "" @@ -235876,7 +235364,7 @@ - eccodes: "" - references: "PMID:8145081" - subsystem: - - "Exchange/demand reactions" + - "Transport reactions" - confidence_score: 0 - !!omap - id: "MAR10390" @@ -250224,8 +249712,8 @@ - id: "MAR11290" - name: "Transport of Hexanoate (N-C6:0), Mitochondrial" - metabolites: !!omap - - MAM03684c: 1 - - MAM03684m: -1 + - MAM02120c: 1 + - MAM02120m: -1 - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "" @@ -250239,23 +249727,8 @@ - id: "MAR11291" - name: "Transport of Hexanoate (N-C6:0), Peroxisome" - metabolites: !!omap - - MAM03684c: 1 - - MAM03684x: -1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "" - - subsystem: - - "Transport reactions" - - confidence_score: 0 - - !!omap - - id: "MAR11292" - - name: "Transport of Hexanoate (N-C6:0), Extracellular" - - metabolites: !!omap - - MAM03684c: -1 - - MAM03684e: 1 + - MAM02120c: 1 + - MAM02120x: -1 - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "" @@ -250265,20 +249738,6 @@ - subsystem: - "Transport reactions" - confidence_score: 0 - - !!omap - - id: "MAR11293" - - name: "Exchange of Hexanoate (N-C6:0)" - - metabolites: !!omap - - MAM03684e: -1 - - lower_bound: -1000 - - upper_bound: 1000 - - gene_reaction_rule: "" - - rxnNotes: "" - - eccodes: "" - - references: "" - - subsystem: - - "Exchange/demand reactions" - - confidence_score: 0 - !!omap - id: "MAR11294" - name: "Hydrolysis of Fatty Acyl Coenzyme A (14:1)" @@ -250652,7 +250111,7 @@ - eccodes: "" - references: "PMID:21749716" - subsystem: - - "Heme synthesis" + - "Porphyrin metabolism" - confidence_score: 0 - !!omap - id: "MAR11317" @@ -251087,8 +250546,6 @@ - id: "MAR11346" - name: "Lipoamide Transport" - metabolites: !!omap - - MAM02039c: 1 - - MAM02039e: -1 - MAM02393c: 1 - MAM02393e: -1 - lower_bound: -1000 @@ -251309,11 +250766,9 @@ - id: "MAR11361" - name: "Transport of Lipoamide, Mitochondrial" - metabolites: !!omap - - MAM02039i: -1 - - MAM02039m: 1 - MAM02393c: -1 - MAM02393m: 1 - - lower_bound: 0 + - lower_bound: -1000 - upper_bound: 1000 - gene_reaction_rule: "" - rxnNotes: "" @@ -252044,7 +251499,7 @@ - eccodes: "" - references: "PMID:21749716" - subsystem: - - "Heme synthesis" + - "Porphyrin metabolism" - confidence_score: 0 - !!omap - id: "MAR11407" @@ -254180,7 +253635,7 @@ - confidence_score: 0 - !!omap - id: "MAR11544" - - name: "Formation of Hexanoic Acid" + - name: "Hexanoyl-CoA hydrolase" - metabolites: !!omap - MAM01597c: 1 - MAM02039c: 1 @@ -254189,9 +253644,9 @@ - MAM02122c: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "" + - gene_reaction_rule: "Acot12" - rxnNotes: "https://www.springer.com/gp/book/9789400957800" - - eccodes: "" + - eccodes: "3.1.2.2" - references: "PMID:8371066" - subsystem: - "Fatty acid oxidation" @@ -281508,25 +280963,6 @@ - subsystem: - "Retinol metabolism" - confidence_score: 0 - - !!omap - - id: "MAR20012" - - name: "MAR20012" - - metabolites: !!omap - - MAM02039c: 2 - - MAM02040c: -1 - - MAM02552c: -1 - - MAM02553c: 1 - - MAM02832c: -1 - - MAM02833c: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Aldh1a3" - - rxnNotes: "" - - eccodes: "1.2.1.36" - - references: "" - - subsystem: - - "Retinol metabolism" - - confidence_score: 0 - !!omap - id: "MAR20013" - name: "MAR20013" @@ -281586,13 +281022,13 @@ - id: "MAR20021" - name: "MAR20021" - metabolites: !!omap + - MAM01828r: 1 - MAM02039r: 1 - MAM02040r: 1 - MAM02457r: -1 - MAM02630r: -1 - MAM20018r: 1 - MAM20019r: -1 - - MAM20020r: 1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "Cyp2e1" @@ -281606,13 +281042,13 @@ - id: "MAR20022" - name: "MAR20022" - metabolites: !!omap + - MAM01828i: 1 - MAM02039i: 1 - MAM02040i: 1 - MAM02457i: -1 - MAM02630i: -1 + - MAM20019i: -1 - MAM20021i: 1 - - MAM20022i: -1 - - MAM20023i: 1 - lower_bound: 0 - upper_bound: 1000 - gene_reaction_rule: "Cyp2e1" @@ -281627,11 +281063,11 @@ - name: "MAR20023" - metabolites: !!omap - MAM01784r: -1 + - MAM01828r: 1 - MAM02039r: 1 - MAM02040r: 1 - MAM02630r: -1 - MAM20019r: -1 - - MAM20020r: 1 - MAM20024r: 1 - lower_bound: 0 - upper_bound: 1000 @@ -281647,11 +281083,11 @@ - name: "MAR20024" - metabolites: !!omap - MAM01784i: -1 + - MAM01828i: 1 - MAM02039i: 1 - MAM02040i: 1 - MAM02630i: -1 - - MAM20022i: -1 - - MAM20023i: 1 + - MAM20019i: -1 - MAM20025i: 1 - lower_bound: 0 - upper_bound: 1000 @@ -281667,11 +281103,11 @@ - name: "MAR20025" - metabolites: !!omap - MAM01689r: -1 + - MAM01828r: 1 - MAM02039r: 1 - MAM02040r: 1 - MAM02630r: -1 - MAM20019r: -1 - - MAM20020r: 1 - MAM20026r: 1 - lower_bound: 0 - upper_bound: 1000 @@ -281687,11 +281123,11 @@ - name: "MAR20026" - metabolites: !!omap - MAM01689i: -1 + - MAM01828i: 1 - MAM02039i: 1 - MAM02040i: 1 - MAM02630i: -1 - - MAM20022i: -1 - - MAM20023i: 1 + - MAM20019i: -1 - MAM20027i: 1 - lower_bound: 0 - upper_bound: 1000 @@ -281706,12 +281142,12 @@ - id: "MAR20027" - name: "MAR20027" - metabolites: !!omap + - MAM01828r: 1 - MAM02039r: 1 - MAM02040r: 1 - MAM02344r: -1 - MAM02630r: -1 - MAM20019r: -1 - - MAM20020r: 1 - MAM20028r: 1 - lower_bound: 0 - upper_bound: 1000 @@ -281726,12 +281162,12 @@ - id: "MAR20028" - name: "MAR20028" - metabolites: !!omap + - MAM01828i: 1 - MAM02039i: 1 - MAM02040i: 1 - MAM02344i: -1 - MAM02630i: -1 - - MAM20022i: -1 - - MAM20023i: 1 + - MAM20019i: -1 - MAM20029i: 1 - lower_bound: 0 - upper_bound: 1000 @@ -281746,12 +281182,12 @@ - id: "MAR20029" - name: "MAR20029" - metabolites: !!omap + - MAM01828r: 1 - MAM02039r: 1 - MAM02040r: 1 - MAM02494r: -1 - MAM02630r: -1 - MAM20019r: -1 - - MAM20020r: 1 - MAM20030r: 1 - lower_bound: 0 - upper_bound: 1000 @@ -281766,12 +281202,12 @@ - id: "MAR20030" - name: "MAR20030" - metabolites: !!omap + - MAM01828i: 1 - MAM02039i: 1 - MAM02040i: 1 - MAM02494i: -1 - MAM02630i: -1 - - MAM20022i: -1 - - MAM20023i: 1 + - MAM20019i: -1 - MAM20031i: 1 - lower_bound: 0 - upper_bound: 1000 @@ -281945,9 +281381,9 @@ - metabolites: !!omap - MAM02039c: 2 - MAM02040c: -1 + - MAM02120c: 1 - MAM02554c: -1 - MAM02555c: 1 - - MAM03684c: 1 - MAM20037c: -1 - lower_bound: 0 - upper_bound: 1000 @@ -282768,23 +282204,6 @@ - subsystem: - "Fatty acid metabolism" - confidence_score: 0 - - !!omap - - id: "MAR20089" - - name: "MAR20089" - - metabolites: !!omap - - MAM01107c: -1 - - MAM01596c: 1 - - MAM02039c: -1 - - MAM02897c: 1 - - lower_bound: 0 - - upper_bound: 1000 - - gene_reaction_rule: "Ddc" - - rxnNotes: "" - - eccodes: "4.1.1.28" - - references: "" - - subsystem: - - "Tryptophan metabolism" - - confidence_score: 0 - !!omap - id: "MAR20090" - name: "MAR20090" @@ -283217,6 +282636,985 @@ - subsystem: - "Miscellaneous" - confidence_score: 0 + - !!omap + - id: "MAR20115" + - name: "MAR20115" + - metabolites: !!omap + - MAM01334c: -1 + - MAM01334x: 1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "Slc25a17" + - rxnNotes: "" + - eccodes: "" + - references: "PMID:22185573" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20116" + - name: "MAR20116" + - metabolites: !!omap + - MAM01285c: -1 + - MAM01285x: 1 + - lower_bound: -1000 + - upper_bound: 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- MAM03130m: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "Slc25a33" + - rxnNotes: "" + - eccodes: "" + - references: "PMID:25320081" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20162" + - name: "MAR20162" + - metabolites: !!omap + - MAM03106c: -1 + - MAM03106m: 1 + - MAM03130c: 1 + - MAM03130m: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "Slc25a33" + - rxnNotes: "" + - eccodes: "" + - references: "PMID:25320081" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20163" + - name: "MAR20163" + - metabolites: !!omap + - MAM01756c: -1 + - MAM01756m: 1 + - MAM03130c: 1 + - MAM03130m: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "Slc25a33" + - rxnNotes: "" + - eccodes: "" + - references: "PMID:25320081" + - subsystem: + - "Transport reactions" + - confidence_score: 0 + - !!omap + - id: "MAR20164" + - name: "MAR20164" + - 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metabolites: !!omap + - MAM01828c: 1 + - MAM03102m: 1 + - MAM03103m: -1 + - MAM20019c: -1 + - lower_bound: -1000 + - upper_bound: 1000 + - gene_reaction_rule: "Dhodh" + - rxnNotes: "" + - eccodes: "" + - references: "PMID:34428349" + - subsystem: + - "Miscellaneous" + - confidence_score: 0 + - !!omap + - id: "MAR20168" + - name: "MAR20168" + - metabolites: !!omap + - MAM00209c: -1 + - MAM02393m: 1 + - lower_bound: 0 + - upper_bound: 1000 + - gene_reaction_rule: "Lipt1" + - rxnNotes: "" + - eccodes: "" + - references: "PMID:29987032" + - subsystem: + - "Miscellaneous" + - confidence_score: 0 + - !!omap + - id: "MAR20169" + - name: "Butyryl-CoA hydrolase" + - metabolites: !!omap + - MAM01410c: 1 + - MAM01412c: -1 + - MAM01597c: 1 + - MAM02039c: 1 + - MAM02040c: -1 + - lower_bound: 0 + - upper_bound: 1000 + - gene_reaction_rule: "Acot12" + - rxnNotes: "" + - eccodes: "3.1.2.2" + - references: "" + - subsystem: + - "Acyl-CoA hydrolysis" + - confidence_score: 0 + - !!omap + - id: "MAR20170" + - name: "Octanoyl-CoA hydrolase" + - metabolites: !!omap + - MAM01597c: 1 + - MAM02039c: 1 + - MAM02040c: -1 + - MAM02642c: 1 + - MAM02644c: -1 + - lower_bound: 0 + - upper_bound: 1000 + - gene_reaction_rule: "Acot7" + - rxnNotes: "" + - eccodes: "3.1.2.2" + - references: "" + - subsystem: + - "Acyl-CoA hydrolysis" + - confidence_score: 0 + - !!omap + - id: "MAR20171" + - name: "Decanoyl-CoA hydrolase" + - metabolites: !!omap + - MAM01597c: 1 + - MAM01648c: 1 + - MAM01650c: -1 + - MAM02039c: 1 + - MAM02040c: -1 + - lower_bound: 0 + - upper_bound: 1000 + - gene_reaction_rule: "Acot7" + - rxnNotes: "" + - eccodes: "3.1.2.2" + - references: "" + - subsystem: + - "Acyl-CoA hydrolysis" + - confidence_score: 0 + - !!omap + - id: "MAR20172" + - name: "Undecanoyl-CoA hydrolase" + - metabolites: !!omap + - MAM01597c: 1 + - MAM02039c: 1 + - MAM02040c: -1 + - MAM03116c: -1 + - MAM03117c: 1 + - lower_bound: 0 + - upper_bound: 1000 + - gene_reaction_rule: "Acot7" + - rxnNotes: "" + - eccodes: "3.1.2.2" + - references: "" + - subsystem: + - "Acyl-CoA hydrolysis" + - confidence_score: 0 - !!omap - id: "MAR15001" - name: "" @@ -283518,9 +283916,6 @@ - !!omap - id: "Acacb" - name: "Acacb" - - !!omap - - id: "Acad10" - - name: "Acad10" - !!omap - id: "Acad11" - name: "Acad11" @@ -288159,9 +288554,6 @@ - !!omap - id: "Ogdh" - name: "Ogdh" - - !!omap - - id: "Ogdhl" - - name: "Ogdhl" - !!omap - id: "Ogt" - name: "Ogt" @@ -290196,15 +290588,27 @@ - !!omap - id: "Slc25a32" - name: "Slc25a32" + - !!omap + - id: "Slc25a33" + - name: "Slc25a33" + - !!omap + - id: "Slc25a36" + - name: "Slc25a36" - !!omap - id: "Slc25a37" - name: "Slc25a37" - !!omap - id: "Slc25a38" - name: "Slc25a38" + - !!omap + - id: "Slc25a39" + - name: "Slc25a39" - !!omap - id: "Slc25a4" - name: "Slc25a4" + - !!omap + - id: "Slc25a40" + - name: "Slc25a40" - !!omap - id: "Slc25a42" - name: "Slc25a42" @@ -291000,6 +291404,12 @@ - !!omap - id: "Th" - name: "Th" + - !!omap + - id: "Them4" + - name: "Them4" + - !!omap + - id: "Them5" + - name: "Them5" - !!omap - id: "Thnsl1" - name: "Thnsl1" diff --git a/model/dependencies.txt b/model/dependencies.txt index 0d92e48..89c7373 100644 --- a/model/dependencies.txt +++ b/model/dependencies.txt @@ -2,4 +2,4 @@ MATLAB 9.10.0.1602886 (R2021a) libSBML 5.19.0 RAVEN_toolbox 2.7.6 COBRA_toolbox 3.4.0 -Human-GEM 1.17.0 +Human-GEM 1.18.0 diff --git a/model/metabolites.tsv b/model/metabolites.tsv index 2a68fca..90ecef1 100644 --- a/model/metabolites.tsv +++ b/model/metabolites.tsv @@ -1463,7 +1463,6 @@ mets metBiGGID metChEBIID metEHMNID metHMDBID metHMR2ID metHepatoNET1ID metKEGGI "MAM00923c" "cala" "CHEBI:18261" "" "HMDB0000026" "m00923c" "HC00975" "C02642" "" "MNXM802" "111" "cala" "m00923c" "MAM00923" "MAM00924c" "42A3HP24DB" "" "" "" "m00924c" "HC01547" "C05645" "" "MNXM163203;MNXM4997" "440741" "42A3HP24DB" "m00924c" "MAM00924" "MAM00925c" "" "" "CE3086" "" "m00925c" "" "" "" "MNXM166294" "10948689" "CE3086" "m00925c" "MAM00925" -"MAM00926c" "4aphdob" "CHEBI:17442" "" "HMDB0000978" "m00926c" "" "C01252" "" "MNXM163204" "472" "4aphdob" "m00926c" "MAM00926" "MAM00927c" "" "" "" "" "m00927c" "" "C19602" "" "MNXM14691" "" "M00927" "m00927c" "MAM00927" "MAM00928c" "" "" "" "" "m00928c" "" "C19605" "" "MNXM14692" "" "M00928" "m00928c" "MAM00928" "MAM00929c" "" "" "" "" "m00929c" "" "C19574" "" "MNXM4356" "" "M00929" "m00929c" "MAM00929" @@ -2854,7 +2853,6 @@ mets metBiGGID metChEBIID metEHMNID metHMDBID metHMR2ID metHepatoNET1ID metKEGGI "MAM01700l" "dhf" "CHEBI:15633" "" "" "m01700l" "HC00340" "C00415" "" "MNXM281" "98792" "dhf" "m01700l" "MAM01700" "MAM01700m" "dhf" "CHEBI:15633" "" "" "m01700m" "HC00340" "C00415" "" "MNXM281" "98792" "dhf" "m01700m" "MAM01700" "MAM01700e" "dhf" "CHEBI:15633" "" "" "m01700s" "HC00340" "C00415" "" "MNXM281" "98792" "dhf" "m01700s" "MAM01700" -"MAM01701c" "dhlam" "CHEBI:17694" "" "HMDB0000985" "m01701c" "HC00437" "C00579" "" "MNXM1277" "663" "dhlam" "m01701c" "MAM01701" "MAM01701m" "dhlam" "CHEBI:17694" "" "HMDB0000985" "m01701m" "HC00437" "C00579" "" "MNXM1277" "663" "dhlam" "m01701m" "MAM01701" "MAM01702c" "" "CHEBI:18047" "" "HMDB0012210" "m01702c" "" "C02147" "LMFA01130003" "MNXM3585" "421" "C02147" "m01702c" "MAM01702" "MAM01704c" "" "CHEBI:17001" "" "" "m01704c" "HC01361" "C04874" "" "MNXM993" "65074" "HC01361" "m01704c" "MAM01704" @@ -3117,6 +3115,7 @@ mets metBiGGID metChEBIID metEHMNID metHMDBID metHMR2ID metHepatoNET1ID metKEGGI "MAM01827l" "" "" "" "" "m01827l" "HC01852" "C00393" "PROTEIN" "MNXM5157" "" "HC01852" "m01827l" "MAM01827" "MAM01827e" "" "" "" "" "m01827s" "HC01852" "C00393" "PROTEIN" "MNXM5157" "" "HC01852" "m01827s" "MAM01827" "MAM01828c" "fmn" "CHEBI:17621" "" "HMDB0001520" "m01828c" "HC00064" "C00061" "" "MNXM119" "643976" "fmn" "m01828c" "MAM01828" +"MAM01828x" "fmn" "CHEBI:17621" "" "HMDB0001520" "" "" "C00061" "" "MNXM119" "643976" "" "" "MAM01828" "MAM01829g" "fn2m2masn" "CHEBI:32984" "" "" "m01829g" "" "G00016" "" "MNXM12419" "" "fn2m2masn" "m01829g" "MAM01829" "MAM01830c" "fol" "CHEBI:27470" "" "HMDB0000121" "m01830c" "HC00396" "C00504" "" "MNXM617" "6037" "fol" "m01830c" "MAM01830" "MAM01830m" "fol" "CHEBI:27470" "" "HMDB0000121" "m01830m" "HC00396" "C00504" "" "MNXM617" "6037" "fol" "m01830m" "MAM01830" @@ -3651,8 +3650,10 @@ mets metBiGGID metChEBIID metEHMNID metHMDBID metHMR2ID metHepatoNET1ID metKEGGI "MAM02119l" "6thf" "" "" "" "m02119l" "" "" "" "MNXM3616" "169691" "6thf" "m02119l" "MAM02119" "MAM02119m" "6thf" "" "" "" "m02119m" "" "" "" "MNXM3616" "169691" "6thf" "m02119m" "MAM02119" "MAM02119e" "6thf" "" "" "" "m02119s" "" "" "" "MNXM3616" "169691" "6thf" "m02119s" "MAM02119" -"MAM02120c" "" "CHEBI:17120;CHEBI:30776" "" "HMDB0000535" "m02120c" "" "C01585" "LMFA01010006" "MNXM1653" "" "caproic" "m02120c" "MAM02120" -"MAM02120e" "" "CHEBI:17120;CHEBI:30776" "" "HMDB0000535" "m02120s" "" "C01585" "LMFA01010006" "MNXM1653" "" "caproic" "m02120s" "MAM02120" +"MAM02120c" "hxa" "CHEBI:17120;CHEBI:30776" "" "HMDB0000535" "m02120c" "" "C01585" "LMFA01010006" "MNXM1653" "" "caproic" "m02120c" "MAM02120" +"MAM02120e" "hxa" "CHEBI:17120;CHEBI:30776" "" "HMDB0000535" "m02120s" "" "C01585" "LMFA01010006" "MNXM1653" "" "caproic" "m02120s" "MAM02120" +"MAM02120x" "hxa" "CHEBI:17120;CHEBI:30776" "" "HMDB0000535" "" "" "C01585" "LMFA01010006" "MNXM1653" "" "caproic" "" "MAM02120" +"MAM02120m" "hxa" "CHEBI:17120;CHEBI:30776" "" "HMDB0000535" "" "" "C01585" "LMFA01010006" "MNXM1653" "" "caproic" "" "MAM02120" "MAM02121c" "" "" "" "" "m02121c" "HC01592" "C05749" "" "MNXM23683" "" "HC01592" "m02121c" "MAM02121" "MAM02122c" "" "CHEBI:27540" "" "HMDB0002845" "m02122c" "HC01409" "C05270" "LMFA07050001" "MNXM162502;MNXM553" "440611" "hxcoa" "m02122c" "MAM02122" "MAM02122m" "" "CHEBI:27540" "" "HMDB0002845" "m02122m" "HC01409" "C05270" "LMFA07050001" "MNXM162502;MNXM553" "440611" "hxcoa" "m02122m" "MAM02122" @@ -4079,8 +4080,6 @@ mets metBiGGID metChEBIID metEHMNID metHMDBID metHMR2ID metHepatoNET1ID metKEGGI "MAM02396n" "" "CHEBI:6499" "" "HMDB0005082" "m02396n" "" "C06315" "LMFA03040002" "MNXM12130" "5280915" "C06315" "m02396n" "MAM02396" "MAM02396x" "" "CHEBI:6499" "" "HMDB0005082" "m02396p" "" "C06315" "LMFA03040002" "MNXM12130" "5280915" "C06315" "m02396p" "MAM02396" "MAM02396r" "" "CHEBI:6499" "" "HMDB0005082" "m02396r" "" "C06315" "LMFA03040002" "MNXM12130" "5280915" "C06315" "m02396r" "MAM02396" -"MAM02397c" "" "" "" "" "m02397c" "" "C16239" "" "MNXM19093" "" "M02397" "m02397c" "MAM02397" -"MAM02398c" "" "" "CE5656" "" "m02398c" "" "C16238" "" "MNXM2392" "23724672" "CE5656" "m02398c" "MAM02398" "MAM02399c" "" "" "CE2102" "" "m02399c" "" "" "" "MNXM60228" "53481572" "CE2102" "m02399c" "MAM02399" "MAM02401c" "" "CHEBI:29160" "" "" "m02401c" "" "C03127" "" "MNXM89832" "" "M02401" "m02401c" "MAM02401" "MAM02402c" "" "CHEBI:16325" "" "HMDB0000761" "m02402c" "HC02191" "C03990" "LMST04010003" "MNXM886" "11740284" "HC02191" "m02402c" "MAM02402" @@ -6651,7 +6650,6 @@ mets metBiGGID metChEBIID metEHMNID metHMDBID metHMR2ID metHepatoNET1ID metKEGGI "MAM03814c" "pchollinl_hs" "CHEBI:28733" "" "" "" "" "" "" "" "" "pchollinl_hs" "pchollinl_hs_c" "MAM03814" "MAM03856c" "pelinl_hs" "CHEBI:83058" "" "" "" "" "" "" "" "" "pelinl_hs" "pelinl_hs_c" "MAM03856" "MAM03569c" "eidi1114ac" "CHEBI:603631" "" "HMDB0005060" "" "" "C16525" "" "" "6439848" "eidi1114ac" "eidi1114ac_c" "MAM03569" -"MAM03684c" "hxa" "CHEBI:17120" "" "" "" "" "" "" "MNXM1653" "" "hxa" "hxa_c" "MAM03684" "MAM03976c" "tetdeca511ac" "" "" "" "" "" "" "" "" "" "tetdeca511ac" "tetdeca511ac_c" "MAM03976" "MAM03619c" "glyc2p" "CHEBI:58083" "" "" "" "" "" "" "MNXM2527" "" "glyc2p" "glyc2p_c" "MAM03619" "MAM03401c" "aclys" "" "" "" "" "" "" "" "" "" "aclys" "aclys_c" "MAM03401" @@ -6794,8 +6792,6 @@ mets metBiGGID metChEBIID metEHMNID metHMDBID metHMR2ID metHepatoNET1ID metKEGGI "MAM03619e" "glyc2p" "" "" "" "" "" "" "" "MNXM2527" "" "glyc2p" "glyc2p_s" "MAM03619" "MAM01998e" "glyclt" "CHEBI:17497" "" "HMDB0000115" "" "" "C00160" "" "MNXM222" "757" "glyclt" "m01998s" "MAM01998" "MAM03232e" "3hpppn" "" "" "" "" "" "" "" "MNXM1634" "" "3hpppn" "3hpppn_s" "MAM03232" -"MAM03684m" "hxa" "" "" "" "" "" "" "" "MNXM1653" "" "hxa" "hxa_m" "MAM03684" -"MAM03684x" "hxa" "" "" "" "" "" "" "" "MNXM1653" "" "hxa" "hxa_p" "MAM03684" "MAM02169e" "ind3ac" "CHEBI:16411" "" "HMDB0000197" "" "" "C00954" "" "MNXM383" "802" "ind3ac" "m02169s" "MAM02169" "MAM02350e" "Lcyst" "CHEBI:21260" "" "HMDB0002757" "" "" "C00506" "" "MNXM713" "25701" "Lcyst" "m02350s" "MAM02350" "MAM02413c" "Lpipecol" "CHEBI:30913" "" "HMDB0000716" "" "" "C00408" "" "MNXM684" "439227" "Lpipecol" "m02413c" "MAM02413" @@ -7329,7 +7325,6 @@ mets metBiGGID metChEBIID metEHMNID metHMDBID metHMR2ID metHepatoNET1ID metKEGGI "MAM04078c" "" "" "" "" "" "" "" "" "" "" "xolest204_hs" "xolest204_hs_c" "MAM04078" "MAM04080c" "xolest226_hs" "" "" "" "" "" "" "" "" "" "xolest226_hs" "xolest226_hs_c" "MAM04080" "MAM02908e" "sphmyln_hs" "CHEBI:17636" "" "" "" "HC02007" "C00550" "LMSP03010000" "MNXM5930" "" "sphmyln_hs" "m02908s" "MAM02908" -"MAM03684e" "hxa" "" "" "" "" "" "" "" "MNXM1653" "" "hxa" "hxa_s" "MAM03684" "MAM01954c" "gncore1" "" "" "" "" "" "" "" "MNXM18091" "" "gncore1" "m01954c" "MAM01954" "MAM01954e" "gncore1" "" "" "" "" "" "" "" "MNXM18091" "" "gncore1" "m01954s" "MAM01954" "MAM03394c" "Lhcystin" "" "" "" "" "" "" "" "" "" "Lhcystin" "Lhcystin_c" "MAM03394" @@ -8324,13 +8319,14 @@ mets metBiGGID metChEBIID metEHMNID metHMDBID metHMR2ID metHepatoNET1ID metKEGGI "MAM20012m" "" "CHEBI:15801" "" "" "" "" "" "" "MNXM733230" "" "" "" "MAM20012" "MAM20013c" "" "CHEBI:17935" "" "" "" "" "" "" "MNXM2705" "" "" "" "MAM20013" "MAM20018r" "" "CHEBI:132024" "" "" "" "" "" "" "MNXM163133" "" "" "" "MAM20018" -"MAM20019r" "" "CHEBI:57618" "" "" "" "" "" "" "MNXM1107623" "" "" "" "MAM20019" -"MAM20020r" "" "CHEBI:58210" "" "" "" "" "" "" "MNXM1105928" "" "" "" "MAM20020" +"MAM20019c" "C01847" "CHEBI:57618" "" "" "" "" "" "" "MNXM1107623" "" "" "" "MAM20019" +"MAM20019r" "C01847" "CHEBI:57618" "" "" "" "" "" "" "MNXM1107623" "" "" "" "MAM20019" +"MAM01828r" "C00061" "CHEBI:58210" "" "" "" "" "" "" "MNXM1105928" "" "" "MAM20020r" "MAM01828" "MAM20021i" "" "CHEBI:132024" "" "" "" "" "" "" "MNXM163133" "" "" "" "MAM20021" "MAM02040i" "" "CHEBI:15377" "" "" "" "" "" "" "WATER" "" "" "" "MAM02040" "MAM02630i" "" "CHEBI:15379" "" "" "" "" "" "" "MNXM735438" "" "" "" "MAM02630" -"MAM20022i" "" "CHEBI:57618" "" "" "" "" "" "" "MNXM1107623" "" "" "" "MAM20022" -"MAM20023i" "" "CHEBI:58210" "" "" "" "" "" "" "MNXM1105928" "" "" "" "MAM20023" +"MAM20019i" "C01847" "CHEBI:57618" "" "" "" "" "" "" "MNXM1107623" "" "" "MAM20022i" "MAM20019" +"MAM01828i" "C00061" "CHEBI:58210" "" "" "" "" "" "" "MNXM1105928" "" "" "MAM20023i" "MAM01828" "MAM02457i" "" "CHEBI:78043" "" "" "" "" "" "" "MNXM735122" "" "" "" "MAM02457" "MAM20024r" "" "CHEBI:76636" "" "" "" "" "" "" "MNXM146872" "" "" "" "MAM20024" "MAM01784i" "" "CHEBI:58562" "" "" "" "" "" "" "MNXM727959" "" "" "" "MAM01784" diff --git a/model/reactions.tsv b/model/reactions.tsv index 9cc7003..d2166dc 100644 --- a/model/reactions.tsv +++ b/model/reactions.tsv @@ -708,18 +708,17 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR08783" "HISTASE" "" "HMR_8783" "" "R02150" "MNXR95850" "" "RCR11329" "HISTASE" "HMR_8783" "" "RHEA:25625" "" 0 "MAR08784" "IMACTD" "" "HMR_8784" "" "R04065" "MNXR95745" "" "RCR11330" "IMACTD" "HMR_8784" "RHEA:31060" "RHEA:31059" "" 0 "MAR08786" "IMACTD_m" "" "HMR_8786" "" "R04065" "MNXR95745" "" "RCR11331" "IMACTD_m" "HMR_8786" "RHEA:31060" "RHEA:31059" "" 0 -"MAR04239" "2OXOADOXm" "R01933M" "HMR_4239" "r0448" "R01933" "MNXR94818" "" "RCR11332" "2OXOADOXm" "HMR_4239" "RHEA:30796" "RHEA:30795" "" 0 "MAR04241" "" "" "HMR_4241" "" "R03938" "MNXR108541" "" "RCR14332" "HMR_4241" "HMR_4241" "" "RHEA:10024" "" 0 "MAR04288" "SACCD3m" "R00716M" "HMR_4288" "r0180" "R00716" "MNXR104238" "" "RCR11333" "SACCD3m" "HMR_4288" "" "RHEA:19373" "" 0 "MAR04596" "" "R01939C" "HMR_4596" "r0450" "R01939" "MNXR95160" "" "RCR10526" "AATAi" "HMR_4596" "" "RHEA:12601" "" 0 "MAR04597" "" "R01939M" "HMR_4597" "r0450" "R01939" "MNXR95160" "" "RCR11334" "r0450" "HMR_4597" "" "RHEA:12601" "" 0 -"MAR04599" "" "R01940M" "HMR_4599" "r0451" "R01940" "MNXR102246;MNXR107241" "" "RCR10318" "r0451" "HMR_4599" "" "RHEA:12188" "" 0 +"MAR04599" "2OXOADOXm" "R01940M;R01933M" "HMR_4599;HMR_4239" "r0451;r0448" "R01940" "MNXR102246;MNXR107241" "" "RCR10318;RCR11332" "r0451;2OXOADOXm" "HMR_4599;MAR04239;HMR_4239" "RHEA:12189" "RHEA:12188" "" 0 "MAR04667" "r0525" "R02313C" "HMR_4667" "r0525" "R02313" "MNXR105347" "" "RCR11335" "r0525" "HMR_4667" "" "RHEA:24520" "" 0 "MAR04668" "SACCD4m" "" "HMR_4668" "r0526" "R02315" "MNXR104236" "" "RCR11336" "SACCD4m" "HMR_4668" "" "RHEA:10020" "" 0 "MAR04737" "" "R03102M" "HMR_4737" "r0594" "R03102" "MNXR95158" "" "RCR10319" "r0594" "HMR_4737" "" "RHEA:12308" "" 0 "MAR04739" "AASAD3m" "R03102M" "HMR_4739" "" "R03102" "MNXR95158" "" "RCR10527" "AASAD3m" "HMR_4739" "" "RHEA:12308" "" 0 "MAR04740" "" "RE1254C" "HMR_4740" "" "R02317" "MNXR95152" "" "RCR11337" "RE1254C" "HMR_4740" "" "RHEA:25121" "" 1 -"MAR06415" "" "R02571C" "HMR_6415" "r0557" "R02571" "MNXR100213;MNXR107586" "" "RCR14333" "r0557" "HMR_6415" "" "" "" 0 +"MAR06415" "2OXOADOXm" "R02571C;R01933M" "HMR_6415;HMR_4239" "r0557;r0448" "R02571" "MNXR100213;MNXR107586" "" "RCR14333;RCR11332" "r0557;2OXOADOXm" "HMR_6415;MAR04239;HMR_4239" "" "" "" 0 "MAR06974" "" "" "HMR_6974" "r1386" "" "" "" "RCR10159" "" "HMR_6974" "" "" "" 0 "MAR06975" "" "" "HMR_6975" "" "R03875" "MNXR108494" "" "RCR11338" "HMR_6975" "HMR_6975" "" "RHEA:51736" "" 0 "MAR06976" "" "" "HMR_6976" "" "R04866" "MNXR109175" "" "RCR11339" "HMR_6976" "HMR_6976" "" "RHEA:54196" "" 0 @@ -747,8 +746,6 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR08091" "3HXKYNDCL" "" "HMR_8091" "" "" "MNXR94906" "" "RCR11354" "3HXKYNDCL" "HMR_8091" "" "" "" 0 "MAR08092" "3HXKYNOXDA" "" "HMR_8092" "" "R04907" "MNXR94907" "" "RCR11355" "3HXKYNOXDA" "HMR_8092" "" "" "" 0 "MAR08563" "ALDD20xm" "" "HMR_8563" "" "R02678" "MNXR95744" "" "RCR10320" "ALDD20xm" "HMR_8563" "" "RHEA:30867" "" 0 -"MAR08564" "KYNAKGAT" "" "HMR_8564" "" "" "MNXR100948" "" "RCR11356" "KYNAKGAT" "HMR_8564" "" "" "" 0 -"MAR08565" "KYNATESYN" "" "HMR_8565" "" "R03445" "MNXR100949" "" "RCR11357" "KYNATESYN" "HMR_8565" "" "RHEA:42452" "" 0 "MAR08566" "MELATNOX" "" "HMR_8566" "" "" "MNXR101458" "" "RCR11358" "MELATNOX" "HMR_8566" "" "" "" 0 "MAR03935" "r1377" "" "HMR_3935" "r1377" "R06982" "MNXR105462;MNXR99239" "" "RCR11359" "r1377" "HMR_3935" "" "RHEA:22488" "" 0 "MAR04681" "" "" "HMR_4681" "" "R00699" "MNXR102650" "" "RCR10321" "PHYCBOXL" "HMR_4681" "" "RHEA:19717" "" 0 @@ -802,13 +799,12 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR08088" "3AIBTm" "" "HMR_8088" "" "R04188" "MNXR108721;MNXR94851" "" "RCR11385" "3AIBTm" "HMR_8088" "" "RHEA:13993" "" 0 "MAR08787" "MMCDm" "" "HMR_8787" "" "R00923" "MNXR101656" "" "RCR11386" "MMCDm" "HMR_8787" "" "RHEA:21396" "" 0 "MAR03743" "" "RE2117M" "HMR_3743" "" "" "MNXR103611" "" "RCR11387" "RE2117M" "HMR_3743" "" "" "" 0 -"MAR03940" "PHETHPTOX" "R01795C" "HMR_3940" "r0399" "R01795" "MNXR102632;MNXR107174" "" "RCR11388" "r0399" "HMR_3940" "" "RHEA:30787" "" 0 "MAR04214" "TRPO2" "R00678C" "HMR_4214" "r0169" "R00678" "MNXR104944" "" "RCR11389" "TRPO2" "HMR_4214" "" "RHEA:24536" "" 0 "MAR04216" "FKYNH" "R01958C" "HMR_4216" "r0454" "R01958" "MNXR99596" "" "RCR11390" "FKYNH" "HMR_4216" "" "" "" 0 "MAR04218" "LFORKYNHYD" "R03936C" "HMR_4218" "r0646" "R03936" "MNXR101060;MNXR108539" "" "RCR11391" "LFORKYNHYD" "HMR_4218" "" "" "" 0 "MAR04219" "" "R00988C" "HMR_4219" "r0239" "R00988" "MNXR105316;MNXR106774" "" "RCR11392" "r0239" "HMR_4219" "" "" "" 0 "MAR04220" "KYN3OX" "R01960C" "HMR_4220" "r0455" "R01960" "MNXR100947" "" "RCR11393" "KYN3OX" "HMR_4220" "RHEA:20548" "RHEA:20545" "" 0 -"MAR04222" "" "RE1233C" "HMR_4222" "" "" "" "" "RCR11394" "RE1233C" "HMR_4222" "" "" "" 0 +"MAR04222" "" "RE1233C" "HMR_4222" "" "" "" "" "RCR11394" "RE1233C" "HMR_4222;MAR08564+MAR08565" "RHEA:65561" "RHEA:65560" "" 0 "MAR04224" "KYN" "R00987C" "HMR_4224" "r0238" "R00987" "MNXR100946" "" "RCR11395" "KYN" "HMR_4224" "" "RHEA:16813" "" 0 "MAR04225" "HKYNH" "R02668C" "HMR_4225" "r0563" "R02668" "MNXR100656" "" "RCR10534" "HKYNH" "HMR_4225" "" "RHEA:25143" "" 0 "MAR04227" "" "" "HMR_4227" "" "R02670" "MNXR107655" "" "RCR14355" "HMR_4227" "HMR_4227" "" "" "" 0 @@ -954,7 +950,7 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR06888" "" "" "HMR_6888" "" "R03673" "MNXR108329" "" "RCR10544" "DCT" "HMR_6888" "RHEA:13042" "RHEA:13041" "" 0 "MAR06889" "" "RE3201C" "HMR_6889" "" "" "MNXR103829" "" "RCR11479" "RE3201C" "HMR_6889" "" "" "" 0 "MAR07628" "" "" "HMR_7628" "" "R00690" "MNXR106645" "" "RCR11480" "HMR_7628" "HMR_7628" "" "RHEA:10712" "" 0 -"MAR08539" "PHETHPTOX2" "" "HMR_8539" "" "R07211" "MNXR102633" "" "RCR11482" "PHETHPTOX2" "HMR_8539" "" "RHEA:20273" "" 0 +"MAR08539" "PHETHPTOX2" "" "HMR_8539" "" "R07211" "MNXR102633" "" "RCR11482" "PHETHPTOX2" "HMR_8539;MAR03940" "" "RHEA:20273" "" 0 "MAR08794" "PACCOAL" "" "HMR_8794" "" "R02539" "MNXR102315" "" "RCR11483" "PACCOAL" "HMR_8794" "" "RHEA:20956" "" 0 "MAR08795" "PHACCOAGLNAC" "" "HMR_8795" "" "R02576" "MNXR102611" "" "RCR11484" "PHACCOAGLNAC" "HMR_8795" "" "RHEA:21844" "" 0 "MAR08796" "" "" "HMR_8796" "" "R05841" "MNXR102612" "" "RCR11485" "HMR_8796" "HMR_8796" "RHEA:27851" "RHEA:27850" "" 0 @@ -1016,7 +1012,7 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR04708" "" "R02743C" "HMR_4708" "r0568" "R02743" "MNXR105350" "" "RCR14413" "r0568" "HMR_4708" "" "" "" 0 "MAR08769" "GTMLTe" "" "HMR_8769" "" "" "MNXR100452" "" "RCR40314" "GTMLTe" "HMR_8769" "" "" "" 0 "MAR08770" "GGLUCT" "" "HMR_8770" "" "" "MNXR100126" "" "RCR40168" "GGLUCT" "HMR_8770" "" "" "" 0 -"MAR08771" "GTHRDt" "" "HMR_8771" "" "" "MNXR100447" "" "RCR20224" "GTHRDt" "HMR_8771" "RHEA:29792" "RHEA:29791" "" 0 +"MAR08771" "GTHRDt" "" "HMR_8771;HMR_4940;HMR_6391" "r0885;r2520" "" "MNXR100447;MNXR105402;MNXR106328" "" "RCR20224;RCR20265;RCR20063" "GTHRDt;r0885;r2520" "HMR_8771;MAR04940;HMR_4940;MAR06391;HMR_6391" "RHEA:74821" "RHEA:74819" "2.A.29.2.7" 0 "MAR04078" "" "" "HMR_4078" "" "R09076" "" "" "RCR10551" "HMR_4078" "HMR_4078" "" "RHEA:25804" "" 0 "MAR04079" "" "" "HMR_4079" "" "" "" "" "RCR11506" "HMR_4079" "HMR_4079" "" "" "" 0 "MAR04174" "ASP1DC" "R00489C" "HMR_4174" "r0128" "R00489" "MNXR96077" "" "RCR10095" "ASP1DC" "HMR_4174" "" "RHEA:19497" "" 0 @@ -1332,7 +1328,7 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR04589" "" "R01900C" "HMR_4589" "r0426" "R01900" "MNXR105342;MNXR95387" "" "RCR10352" "r0426" "HMR_4589" "" "RHEA:22144" "" 0 "MAR04652" "r0509;SUCD1m" "R02164C" "HMR_4652;HMR_8743" "r0509" "R00408;R02164" "MNXR107340;MNXR99636" "" "RCR14481;RCR11674" "r0509;SUCD1m" "HMR_4652;HMR_8743;MAR08743" "" "RHEA:13713;RHEA:30343" "" 0 "MAR06413" "" "R03316M" "HMR_6413" "r0620" "R03316" "MNXR105357;MNXR108089" "" "RCR11672" "r0620" "HMR_6413" "" "" "" 0 -"MAR06414" "" "R02570C" "HMR_6414" "r0556" "R02570" "MNXR107585;MNXR95656" "" "RCR14482" "r0556" "HMR_6414" "" "RHEA:15213" "" 0 +"MAR06414" "" "R02570C" "HMR_6414" "r0556" "R02570" "MNXR107585;MNXR95656" "" "RCR14482" "r0556" "HMR_6414" "RHEA:15216" "RHEA:15213" "" 0 "MAR07704" "GLXO2p" "" "HMR_7704" "" "R00466" "MNXR100305" "" "RCR10605" "GLXO2p" "HMR_7704" "" "RHEA:14837" "" 0 "MAR07706" "GLYCTO1p" "" "HMR_7706" "" "R00475" "MNXR100338" "" "RCR11673" "GLYCTO1p" "HMR_7706" "" "RHEA:25311" "" 0 "MAR08772" "KHK2" "" "HMR_8772" "" "" "MNXR100937" "" "RCR11675" "KHK2" "HMR_8772" "" "" "" 0 @@ -1665,12 +1661,8 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR02469" "" "RE3264C" "HMR_2469" "" "" "" "" "RCR11942" "RE3264C" "HMR_2469" "" "" "" 0 "MAR02470" "" "RE3264R" "HMR_2470" "" "" "MNXR103858" "" "RCR11943" "RE3264R" "HMR_2470" "" "" "" 0 "MAR06397" "" "RE2882C" "HMR_6397" "" "" "" "" "RCR10619" "HMR_6397" "HMR_6397" "" "" "" 0 -"MAR06398" "" "R07770C" "HMR_6398" "" "R07770" "MNXR101081" "" "RCR14489" "RE1944C" "HMR_6398" "" "RHEA:12913" "" 0 -"MAR06399" "" "R07771C" "HMR_6399" "" "R07771" "MNXR111358" "" "RCR14490" "HMR_6399" "HMR_6399" "" "RHEA:20473" "" 0 -"MAR06400" "" "R07768C" "HMR_6400" "" "R07768" "MNXR111356" "" "RCR11944" "HMR_6400" "HMR_6400" "" "" "" 0 -"MAR06401" "" "R07769C" "HMR_6401" "" "R07769" "MNXR111357" "" "RCR11945" "HMR_6401" "HMR_6401" "" "" "" 0 -"MAR06402" "" "R07766C" "HMR_6402" "" "R07766" "MNXR111354" "" "RCR11946" "HMR_6402" "HMR_6402" "" "RHEA:17665" "" 0 -"MAR06403" "" "R07767C" "HMR_6403" "" "R07767" "MNXR111355" "" "RCR11947" "HMR_6403" "HMR_6403" "" "RHEA:16585" "" 0 +"MAR06402" "" "R07766C;R07769C" "HMR_6402;HMR_6401" "" "R07766;R07769" "MNXR111354" "" "RCR11946;RCR11945" "HMR_6402;HMR_6401" "HMR_6402;HMR_6401;MAR06401" "RHEA:17666" "RHEA:17665" "" 0 +"MAR06403" "" "R07767C;R07768C" "HMR_6403;HMR_6400" "" "R07767;R07768" "MNXR111355" "" "RCR11947;RCR11948" "HMR_6403;HMR_6400" "HMR_6403;HMR_6400;MAR06400" "RHEA:16586" "RHEA:16585" "" 0 "MAR06404" "" "R08550C" "HMR_6404" "" "R08550" "MNXR112089" "" "RCR14491" "HMR_6404" "HMR_6404" "" "" "" 0 "MAR02472" "HMR_2472" "RE3109C" "HMR_2472" "" "" "" "" "RCR11948" "HMR_2472" "HMR_2472" "" "" "" 0 "MAR02475" "RE3110C" "RE3110C" "HMR_2475" "" "" "MNXR103792" "" "RCR11949" "RE3110C" "HMR_2475" "" "" "" 0 @@ -3422,10 +3414,8 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR00448" "GLYKm" "R00847C" "HMR_0448" "r0204" "R00847" "MNXR100348" "" "RCR13153" "GLYKm" "HMR_0448" "" "RHEA:21644" "" 0 "MAR00450" "GLYK" "R00847C" "HMR_0450" "r0203" "R00847" "MNXR100348" "" "RCR10853" "GLYK" "HMR_0450" "" "RHEA:21644" "" 0 "MAR00468" "CEPTC" "" "HMR_0468" "r1288" "" "MNXR96592" "" "RCR13154" "HMR_0468" "HMR_0468" "" "" "" 0 -"MAR00478" "" "" "HMR_0478" "" "R00844" "MNXR99876" "R-HSA-75889" "RCR14575" "HMR_0478" "HMR_0478" "RHEA:11098" "RHEA:11096" "" 0 -"MAR00479" "G3PD1" "R00842C" "HMR_0479" "r0201" "R00842" "MNXR99876" "" "RCR14576" "G3PD1" "HMR_0479" "" "RHEA:11092" "" 0 +"MAR00479" "G3PD1" "R00842C" "HMR_0479;HMR_0478" "r0201" "R00842;R00844" "MNXR99876" "R-HSA-75889" "RCR14576;RCR14575" "G3PD1;HMR_0478" "HMR_0479;HMR_0478;MAR00478" "" "RHEA:11092" "" 0 "MAR00481" "" "R00842C" "HMR_0481" "r0202" "R00842" "MNXR99876" "" "RCR14577" "r0202" "HMR_0481" "" "RHEA:11092" "" 0 -"MAR00482" "G3PD2m" "R00848C" "HMR_0482;HMR_0483" "r0205" "R00848;R00849" "MNXR99875;MNXR106713" "" "RCR14578;RCR21050" "HMR_0482;r0205" "HMR_0482;HMR_0483" "" "RHEA:31283;RHEA:18977" "" 0 "MAR00484" "" "" "HMR_0484" "" "R00855" "MNXR106718" "" "RCR14579" "HMR_0484" "HMR_0484" "" "RHEA:21692" "" 0 "MAR00579" "" "" "HMR_0579" "r1307" "R00851" "" "" "RCR13155" "HMR_0579" "HMR_0579" "" "RHEA:15325" "" 0 "MAR00580" "" "" "HMR_0580" "r1308" "R02241" "" "" "RCR13156" "HMR_0580" "HMR_0580" "" "RHEA:19709" "" 0 @@ -4064,7 +4054,7 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR01702" "" "" "HMR_1702" "r1012" "" "MNXR105423" "" "RCR20518" "" "HMR_1702" "" "" "" 0 "MAR01703" "" "" "HMR_1703" "" "R08739" "MNXR124748" "R-HSA-193452" "RCR13627" "HMR_1703" "HMR_1703" "" "" "" 0 "MAR01704" "" "" "HMR_1704" "" "" "MNXR124227" "R-HSA-193369" "RCR13628" "HMR_1704" "HMR_1704" "" "" "" 0 -"MAR01706" "" "" "HMR_1706" "" "R04809" "MNXR123029" "R-HSA-193535" "RCR13629" "HMR_1706" "HMR_1706" "" "" "" 0 +"MAR01706" "" "" "HMR_1706" "" "R04809" "MNXR123029" "R-HSA-193535" "RCR13629" "HMR_1706" "HMR_1706" "RHEA:47409" "RHEA:47408" "" 0 "MAR01708" "" "" "HMR_1708" "r1021" "R04810" "MNXR124228" "R-HSA-193508" "RCR13630" "HMR_1708" "HMR_1708" "" "" "" 0 "MAR01710" "" "" "HMR_1710" "" "R04811" "MNXR109135" "R-HSA-193533" "RCR13631" "HMR_1710" "HMR_1710" "" "" "" 0 "MAR01716" "" "RE1835X" "HMR_1716" "" "R03974" "MNXR103559" "" "RCR14626" "RE1835X" "HMR_1716" "" "RHEA:31511" "" 0 @@ -4448,7 +4438,7 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR04654" "" "R02235C" "HMR_4654" "r0512" "R02235" "MNXR97399" "" "RCR13812" "r0512" "HMR_4654" "" "" "" 0 "MAR04655" "FOLR2" "R02236C" "HMR_4655" "r0513" "R02236" "MNXR97400" "" "RCR13813" "FOLR2" "HMR_4655" "" "RHEA:31103" "" 0 "MAR04656" "" "R02236C" "HMR_4656" "r0514" "R02236" "MNXR97400" "" "RCR13814" "r0514" "HMR_4656" "" "RHEA:31103" "" 0 -"MAR04665" "" "R02300G" "HMR_4665" "r0522" "R02300" "MNXR99614" "" "RCR13815" "r0522" "HMR_4665" "" "" "" 0 +"MAR04665" "" "R02300G" "HMR_4665" "r0522" "R02300" "MNXR99614" "" "RCR13815" "r0522" "HMR_4665" "RHEA:34768" "RHEA:34767" "" 0 "MAR09726" "" "" "HMR_9726" "" "R03189" "MNXR100282" "" "RCR13816" "HMR_9726" "HMR_9726" "" "RHEA:23240" "" 0 "MAR04666" "" "R02301C" "HMR_4666" "r0523" "R02301" "MNXR99668" "" "RCR13817" "r0523" "HMR_4666" "" "RHEA:10488" "" 0 "MAR07145" "" "" "HMR_7145" "" "R09394" "MNXR112822" "" "RCR10270" "HMR_7145" "HMR_7145" "" "RHEA:49576" "" 0 @@ -4524,7 +4514,7 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR04834" "" "R05046C" "HMR_4834" "r0776" "R05046" "MNXR105382" "" "RCR14690" "r0776" "HMR_4834" "" "" "" 0 "MAR04835" "" "R05048C" "HMR_4835" "r0777" "R05048" "MNXR105383" "" "RCR13860" "r0777" "HMR_4835" "" "" "" 0 "MAR04836" "" "R05048C" "HMR_4836" "r0778" "R05048" "MNXR105383" "" "RCR13861" "r0778" "HMR_4836" "" "" "" 0 -"MAR08538" "THBPT4ACAMDASE" "" "HMR_8538" "" "R04734" "MNXR104802" "" "RCR10142" "THBPT4ACAMDASE" "HMR_8538" "" "RHEA:11920" "" 0 +"MAR08538" "THBPT4ACAMDASE" "" "HMR_8538" "" "R04734" "MNXR104802" "" "RCR10142" "THBPT4ACAMDASE" "HMR_8538;MAR03940" "" "RHEA:11920" "" 0 "MAR08738" "PTHPSn" "" "HMR_8738" "" "R04286" "MNXR103331" "" "RCR14691" "PTHPSn" "HMR_8738" "" "RHEA:22048" "" 0 "MAR08739" "SPRn" "" "HMR_8739" "" "R08208" "MNXR104500" "" "RCR14692" "SPRn" "HMR_8739" "" "RHEA:32627" "" 0 "MAR08740" "DIGALSGALSIDEtg" "" "HMR_8740" "" "" "MNXR97459" "" "RCR13862" "DHPR2" "HMR_8740" "" "" "" 0 @@ -4580,7 +4570,7 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR06643" "" "RE2656C" "HMR_6643" "" "" "" "" "RCR10986" "RETI2" "HMR_6643" "" "" "" 0 "MAR06644" "" "RE1900C" "HMR_6644" "" "R08382" "" "" "RCR10987" "RDH2" "HMR_6644" "RHEA:42055" "RHEA:42052" "" 0 "MAR06645" "" "RE2657C" "HMR_6645" "" "" "" "" "RCR13889" "RETI3" "HMR_6645" "" "" "" 0 -"MAR06646" "" "" "HMR_6646" "" "R02123" "MNXR103412" "" "RCR10227" "RADH" "HMR_6646" "RHEA:16178" "RHEA:16177" "" 0 +"MAR06646" "" "" "HMR_6646" "" "R02123" "MNXR103412" "" "RCR10227" "RADH" "HMR_6646;MAR20012" "RHEA:16178" "RHEA:16177" "" 0 "MAR06647" "" "" "HMR_6647" "" "R02123" "MNXR103412" "" "RCR14700" "HMR_6647" "HMR_6647" "RHEA:16178" "RHEA:16177" "" 0 "MAR06648" "" "RE1906C" "HMR_6648" "" "" "MNXR103569" "" "RCR13890" "HMR_6648" "HMR_6648" "" "" "" 0 "MAR06649" "" "RE1906R" "HMR_6649" "" "" "MNXR103570" "" "RCR13891" "RE1906R" "HMR_6649" "" "" "" 0 @@ -4657,7 +4647,7 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR06510" "" "RE3347C" "HMR_6510" "" "R09748" "MNXR99215" "" "RCR10228" "RE3347C" "HMR_6510" "" "RHEA:30147" "" 0 "MAR06511" "" "" "HMR_6511" "" "R09520" "MNXR99216" "" "RCR13933" "HMR_6511" "HMR_6511" "" "RHEA:30151" "" 0 "MAR04537" "" "R01814C" "HMR_4537" "r0403" "R07213" "MNXR107187" "" "RCR13934" "TRPHYDRO2" "HMR_4537" "" "RHEA:16709" "" 0 -"MAR04545" "5HLTDL" "R02701C" "HMR_4545" "r0564" "R02701" "MNXR107676;MNXR95078" "" "RCR10427" "5HLTDL" "HMR_4545" "RHEA:18534" "RHEA:18533" "" 0 +"MAR04545" "5HLTDL" "R02701C" "HMR_4545" "r0564" "R02701" "MNXR107676;MNXR95078" "" "RCR10427" "5HLTDL" "HMR_4545;MAR020089" "RHEA:18534" "RHEA:18533" "" 0 "MAR04546" "" "" "HMR_4546" "" "R02911" "" "" "RCR14717" "SRTNACT" "HMR_4546" "" "RHEA:25217" "" 0 "MAR04547" "" "" "HMR_4547" "" "R03130" "" "" "RCR14718" "ACSRTNMT" "HMR_4547" "" "RHEA:15573" "" 0 "MAR04548" "" "RE2426C" "HMR_4548" "" "R03629" "MNXR103669;MNXR108309" "" "RCR13935" "" "HMR_4548" "" "" "" 0 @@ -6252,7 +6242,6 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR06383" "HOMt4" "" "HMR_6383" "r2480" "" "MNXR100677" "" "RCR41531" "" "HMR_6383" "" "" "2.A.18.6.8" 0 "MAR06384" "HISt4" "" "HMR_6384" "r2481" "" "MNXR100646" "" "RCR41532" "HISSNAT5tc" "HMR_6384" "" "" "2.A.18.6.2" 0 "MAR06392" "" "" "HMR_6392" "r2505" "" "MNXR106316" "" "RCR41533" "r2505" "HMR_6392" "" "" "3.A.1.208.8" 0 -"MAR06406" "LIPOti" "RT1089" "HMR_6406" "" "" "MNXR101093" "" "RCR41534" "" "HMR_6406" "" "" "" 0 "MAR06424" "AVITE2t" "RT1352" "HMR_6424" "" "" "MNXR96147" "" "RCR40703" "AVITE2t" "HMR_6424" "" "" "" 0 "MAR06439" "" "" "HMR_6439" "" "" "" "" "RCR40704" "HMR_6439" "HMR_6439" "" "" "" 0 "MAR06462" "" "" "HMR_6462" "" "" "" "" "RCR40705" "YVITEt" "HMR_6462" "" "" "" 0 @@ -6586,7 +6575,7 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR09605" "" "" "HMR_9605" "" "" "" "" "RCR41621" "HMR_9605" "HMR_9605" "" "" "" 0 "MAR09606" "" "" "HMR_9606" "" "" "" "" "RCR41622" "GLYSNAT5tc" "HMR_9606" "" "" "" 0 "MAR09607" "" "" "HMR_9607" "" "" "" "" "RCR41623" "HMR_9607" "HMR_9607" "" "" "" 0 -"MAR09608" "" "" "HMR_9608" "" "" "" "" "RCR41624" "HMR_9608" "HMR_9608" "" "" "" 0 +"MAR09608" "LIPOti" "RT1089" "HMR_9608;HMR_6406" "" "" "MNXR101093" "" "RCR41624;RCR41534" "HMR_9608;LIPOti" "HMR_9608;LIPOti;HMR_6406;MAR01483;MAR06406" "RHEA:73380" "RHEA:73379" "" 0 "MAR09609" "" "" "HMR_9609" "" "" "" "" "RCR41625" "HMR_9609" "HMR_9609" "" "" "" 0 "MAR09610" "" "" "HMR_9610" "" "" "" "" "RCR41626" "HMR_9610" "HMR_9610" "" "" "" 0 "MAR09611" "" "" "HMR_9611" "" "" "" "" "RCR40899" "INSTt2r" "HMR_9611" "" "" "" 0 @@ -6643,7 +6632,6 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR08022" "2AMADPTm" "" "HMR_8022" "" "" "MNXR94780" "" "RCR20241" "2AMADPTm" "HMR_8022" "" "" "" 0 "MAR08070" "" "" "HMR_8070" "" "" "" "" "RCR20536" "SLDtm" "HMR_8070" "" "" "" 0 "MAR09015" "" "" "HMR_9015" "" "" "" "" "RCR20135" "AMETtd" "HMR_9015" "" "" "" 0 -"MAR09019" "" "" "HMR_9019" "" "" "" "" "RCR20242" "HMR_9019" "HMR_9019" "" "" "" 0 "MAR09020" "" "" "HMR_9020" "" "" "" "" "RCR20537" "FADtm" "HMR_9020" "" "" "" 0 "MAR00157" "" "" "HMR_0157" "" "" "" "" "RCR20164" "HMR_0157" "HMR_0157" "" "" "" 0 "MAR00158" "" "" "HMR_0158" "r1401" "" "MNXR105470" "" "RCR20165" "r1401" "HMR_0158" "" "" "" 0 @@ -6711,7 +6699,6 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR04754" "PPPG9tm" "" "HMR_4754" "r0976" "" "MNXR103127" "" "RCR20570" "PPPG9tm" "HMR_4754" "RHEA:27649" "RHEA:27646" "3.A.1.210" 0 "MAR04756" "HMR_4756" "" "HMR_4756" "" "" "" "" "RCR20262" "HMR_4756" "HMR_4756" "" "" "" 0 "MAR04760" "PHEMEtm" "" "HMR_4760" "r0880" "" "MNXR102625" "" "RCR20571" "PHEMEtm" "HMR_4760" "" "" "3.A.1.210" 0 -"MAR04843" "" "" "HMR_4843" "r0801" "" "MNXR105390" "" "RCR20168" "r0801" "HMR_4843" "" "" "" 0 "MAR04850" "" "" "HMR_4850" "r0818" "" "MNXR97813" "" "RCR20572" "r0818" "HMR_4850" "" "" "" 0 "MAR04851" "" "" "HMR_4851" "r0819" "" "MNXR105393" "" "RCR20573" "r0819" "HMR_4851" "" "" "2.A.29.2.2" 0 "MAR04852" "AKGMALtm" "" "HMR_4852" "r0820" "" "MNXR95659" "" "RCR20169" "AKGMALtm" "HMR_4852" "" "" "2.A.29.2.2" 0 @@ -6733,7 +6720,6 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR04914" "COAtim" "" "HMR_4914" "r0863" "" "MNXR96815" "" "RCR20001" "COAtm" "HMR_4914" "" "" "" 0 "MAR04922" "CO2tm" "" "HMR_4922" "r0868" "" "MNXR96810" "" "RCR20011" "CO2tm" "HMR_4922" "" "" "" 0 "MAR04926" "PYRt2m" "" "HMR_4926" "r0872" "" "MNXR103385" "" "RCR20136" "PYRt2m" "HMR_4926" "" "" "" 0 -"MAR04940" "" "" "HMR_4940" "r0885" "" "MNXR105402" "" "RCR20265" "r0885" "HMR_4940" "" "" "2.A.29.2.7" 0 "MAR04944" "FORtm" "" "HMR_4944" "r0888" "" "MNXR99620" "" "RCR20583" "FORt2m" "HMR_4944" "RHEA:29682" "RHEA:29679" "" 0 "MAR04951" "UREAtm" "" "HMR_4951" "r0897" "" "MNXR105156" "" "RCR20266" "UREAtm" "HMR_4951" "RHEA:32802" "RHEA:32799" "" 0 "MAR04953" "BALAtmr" "" "HMR_4953" "r0900" "" "MNXR95682" "" "RCR20584" "BALAtmr" "HMR_4953" "" "" "" 0 @@ -6844,8 +6830,6 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR06342" "DNDPt58m" "" "HMR_6342" "r2431" "" "MNXR97671" "" "RCR20140" "DNDPt58m" "HMR_6342" "" "" "2.A.29.16.1" 0 "MAR06343" "DNDPt42m" "" "HMR_6343" "r2432" "" "MNXR97655" "" "RCR20276" "DNDPt42m" "HMR_6343" "" "" "2.A.29.16.1" 0 "MAR06389" "r2472" "" "HMR_6389" "r2472" "" "MNXR100321" "" "RCR20616" "r2472" "HMR_6389" "" "" "2.A.1.4.7" 0 -"MAR06391" "" "" "HMR_6391" "r2520" "" "MNXR106328" "" "RCR20063" "r2520" "HMR_6391" "" "" "" 0 -"MAR06408" "" "RT0295" "HMR_6408" "" "" "" "" "RCR21069" "HMR_6408" "HMR_6408" "" "" "" 0 "MAR06431" "" "" "HMR_6431" "" "" "" "" "RCR20617" "HMR_6431" "HMR_6431" "" "" "" 0 "MAR06438" "" "" "HMR_6438" "" "" "" "" "RCR20618" "HMR_6438" "HMR_6438" "" "" "" 0 "MAR06446" "" "" "HMR_6446" "" "" "" "" "RCR20619" "HMR_6446" "HMR_6446" "" "" "" 0 @@ -7012,7 +6996,6 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR04890" "H2Otp" "" "HMR_4890" "r0852" "" "MNXR98641" "" "RCR20016" "H2Otp" "HMR_4890" "RHEA:29670" "RHEA:29667" "" 0 "MAR04900" "O2tp" "" "HMR_4900" "r0857" "" "MNXR102090" "" "RCR20059" "O2tp" "HMR_4900" "" "" "" 0 "MAR04908" "r0860" "" "HMR_4908" "r0860" "R00124" "MNXR96123" "" "RCR20198" "r0860" "HMR_4908" "RHEA:35002" "RHEA:34999" "" 0 -"MAR04915" "COAtp" "" "HMR_4915" "r0864" "" "MNXR96815" "" "RCR20004" "COAtp" "HMR_4915" "" "" "" 0 "MAR04924" "CO2tp" "" "HMR_4924" "r0869" "" "MNXR96810" "" "RCR20149" "CO2tp" "HMR_4924" "" "" "" 0 "MAR04930" "PYRt2p" "" "HMR_4930" "r0874" "" "MNXR103385" "" "RCR20123" "PYRt2p" "HMR_4930" "RHEA:64723" "RHEA:64720" "2.A.1.13.1;2.A.1.13.5" 0 "MAR04945" "" "RT0324" "HMR_4945" "" "" "" "" "RCR20306" "FORMCOAtx" "HMR_4945" "" "" "" 0 @@ -7033,15 +7016,8 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR07646" "DALAxt" "" "HMR_7646" "" "" "MNXR95702" "" "RCR21081" "DALAxt" "HMR_7646" "" "" "" 0 "MAR07705" "GLYCLTtp" "" "HMR_7705" "" "" "MNXR100333" "" "RCR20712" "GLYCLTtp" "HMR_7705" "" "" "" 0 "MAR07707" "GLXtp" "" "HMR_7707" "" "" "MNXR100306" "" "RCR20200" "GLXtp" "HMR_7707" "" "" "" 0 -"MAR07771" "NADtpu" "" "HMR_7771" "" "" "MNXR101881" "" "RCR20023" "NADtx" "HMR_7771" "" "" "" 0 -"MAR07775" "NADHtpu" "" "HMR_7775" "" "" "MNXR101881" "" "RCR20024" "NADHtpu;NADtpu" "HMR_7775" "" "" "" 0 "MAR07777" "NADPtxu" "" "HMR_7777" "" "" "MNXR101896" "" "RCR20713" "NADPtxu" "HMR_7777" "" "" "" 0 "MAR07779" "NADPHtxu" "" "HMR_7779" "" "" "MNXR101894" "" "RCR20311" "NADPHtxu" "HMR_7779" "" "" "" 0 -"MAR07782" "ADPtx" "" "HMR_7782" "" "" "MNXR95484" "" "RCR20201" "ADPtx" "HMR_7782" "" "" "" 0 -"MAR07783" "AMPtp" "" "HMR_7783" "" "" "MNXR95830" "" "RCR20046" "AMPtp" "HMR_7783" "" "" "" 0 -"MAR07785" "ATPtx" "" "HMR_7785" "" "" "MNXR96140" "" "RCR20040" "ATPtx" "HMR_7785" "" "" "" 0 -"MAR07788" "FADH2tx" "" "HMR_7788" "" "" "MNXR99212" "" "RCR20202" "FADH2tx" "HMR_7788" "" "" "" 0 -"MAR07790" "FADtx" "" "HMR_7790" "" "" "MNXR99217" "" "RCR20203" "FADtx" "HMR_7790" "" "" "" 0 "MAR07797" "AKGtp" "" "HMR_7797" "" "" "MNXR95663" "" "RCR20150" "AKGtp" "HMR_7797" "" "" "" 0 "MAR08016" "LYStip" "" "HMR_8016" "" "" "MNXR101269" "" "RCR20033" "LYStip" "HMR_8016" "" "" "" 0 "MAR08020" "THP2Ctp" "" "HMR_8020" "" "" "MNXR104832" "" "RCR20714" "THP2Ctp" "HMR_8020" "" "" "" 0 @@ -8330,7 +8306,7 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR01078" "FUCFUCGALACGLCGALGLUSIDEtg" "" "" "" "" "MNXR99694" "" "" "FUCFUCGALACGLCGALGLUSIDEtg" "FUCFUCGALACGLCGALGLUSIDEtg" "" "" "" 0 "MAR01083" "FUT18g" "" "" "" "" "MNXR99731" "" "" "FUT18g" "FUT18g" "" "" "" 0 "MAR01141" "FUT93g" "" "" "" "" "MNXR99751" "" "" "FUT93g" "FUT93g" "" "" "" 0 -"MAR01169" "G3PD2m" "" "HMR_0483" "r0205" "R00849" "MNXR99878;MNXR106713" "" "RCR21050" "G3PD2m;r0205" "G3PD2m;HMR_0483" "" "RHEA:18977" "" 0 +"MAR01169" "G3PD2m" "R00848C" "HMR_0483;HMR_0482" "r0205" "R00849;R00848" "MNXR99878;MNXR106713;MNXR192664" "" "RCR21050;RCR14578" "G3PD2m;r0205;HMR_0482" "G3PD2m;HMR_0483;HMR_0482;MAR00482;MAR00483" "" "RHEA:18977" "" 0 "MAR01314" "GABAVESSEC" "" "" "" "" "MNXR99916" "" "" "GABAVESSEC" "GABAVESSEC" "" "" "" 0 "MAR01340" "GALFUCGALACGLCGAL14ACGLCGALGLUSIDEtg" "" "" "" "" "MNXR99968" "" "" "GALFUCGALACGLCGAL14ACGLCGALGLUSIDEtg" "GALFUCGALACGLCGAL14ACGLCGALGLUSIDEtg" "" "" "" 0 "MAR01348" "GALGLUSIDEtg" "" "" "" "" "MNXR99974" "" "" "GALGLUSIDEtg" "GALGLUSIDEtg" "" "" "" 0 @@ -8381,7 +8357,6 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR01480" "LEUt5m" "" "" "" "" "MNXR101057" "" "" "LEUt5m" "LEUt5m" "" "" "" 0 "MAR01481" "LGNCCPT2" "" "" "" "" "MNXR101063" "" "" "LGNCCPT2" "LGNCCPT2" "" "" "" 0 "MAR01482" "LGNCCRNt" "" "" "" "" "MNXR101064" "" "" "LGNCCRNt" "LGNCCRNt" "" "" "" 0 -"MAR01483" "LIPOti" "" "" "" "" "MNXR101093" "" "" "LIPOti" "LIPOti" "" "" "" 0 "MAR01485" "L_LACtcm" "" "" "" "" "MNXR100999" "" "" "L_LACtcm" "L_LACtcm" "" "" "" 0 "MAR01486" "LNELDCCRNt" "" "" "" "" "MNXR101102" "" "" "LNELDCCRNt" "LNELDCCRNt" "" "" "" 0 "MAR01487" "LNLCCRNt" "" "" "" "" "MNXR101106" "" "" "LNLCCRNt" "LNLCCRNt" "" "" "" 0 @@ -8730,7 +8705,7 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR02751" "RE1134M" "" "" "" "" "MNXR102255" "" "" "RE1134M" "RE1134M" "" "" "" 0 "MAR02756" "" "" "" "" "" "" "" "" "RE1135G" "RE1135G" "" "" "" 0 "MAR02763" "" "" "" "" "" "" "" "" "RE1135L" "RE1135L" "" "" "" 0 -"MAR02765" "" "" "" "" "" "" "" "" "RE1233M" "RE1233M" "" "" "" 0 +"MAR02765" "" "" "" "" "" "" "" "" "RE1233M" "RE1233M" "RHEA:65561" "RHEA:65560" "" 0 "MAR02767" "RE1309M" "" "" "" "" "MNXR103507" "" "" "RE1309M" "RE1309M" "" "" "" 0 "MAR02779" "RE1342C" "" "" "" "" "MNXR103511" "" "" "RE1342C" "RE1342C" "" "" "" 0 "MAR02781" "RE1447M" "" "" "" "" "MNXR102717" "" "" "RE1447M" "RE1447M" "" "" "" 0 @@ -9070,7 +9045,7 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR04092" "EX_prostgh2_e" "" "" "" "" "MNXR98873" "" "" "EX_prostgh2[e]" "EX_prostgh2[e]" "" "" "" 0 "MAR04094" "EX_prostgi2_e" "" "" "" "" "MNXR98874" "" "" "EX_prostgi2[e]" "EX_prostgi2[e]" "" "" "" 0 "MAR04096" "EX_cdp_e" "" "" "" "" "MNXR98331" "" "" "EX_cdp[e]" "EX_cdp[e]" "" "" "" 0 -"MAR04098" "EX_dtdp_e" "" "" "" "" "MNXR98432" "" "" "EX_dtdp[e]" "EX_dtdp[e]" "" "" "" 0 +"MAR04098" "EX_dtdp_e" "" "" "" "" "MNXR98432" "" "" "EX_dtdp[e]" "EX_dtdp[e];MAR07785" "" "" "" 0 "MAR04100" "EX_HC00955_e" "" "" "" "" "MNXR98138" "" "" "EX_HC00955[e]" "EX_HC00955[e]" "" "" "" 0 "MAR04102" "" "" "" "" "" "" "" "" "EX_HC00002[e]" "EX_HC00002[e]" "" "" "" 0 "MAR04104" "" "" "" "" "" "" "" "" "EX_HC00003[e]" "EX_HC00003[e]" "" "" "" 0 @@ -9522,8 +9497,6 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR07817" "CYSAMOe" "" "" "" "" "MNXR96988" "" "" "CYSAMOe" "CYSAMOe" "RHEA:14410" "RHEA:14409" "" 0 "MAR07819" "Coqe" "" "" "" "" "MNXR97066" "" "" "Coqe" "Coqe" "" "" "" 0 "MAR07821" "DATPtm_cho" "" "" "" "" "MNXR97176" "" "" "DATPtm" "DATPtm" "" "" "" 0 -"MAR07823" "DNDPt51m" "" "" "" "" "MNXR97204" "" "" "DCTPtm" "DCTPtm" "" "" "" 0 -"MAR07926" "DGTPtm" "" "" "" "" "MNXR97327" "" "" "DGTPtm" "DGTPtm" "" "" "" 0 "MAR08111" "DHAPtm" "" "" "" "" "MNXR97366" "" "" "DHAPtc" "DHAPtc" "" "" "" 0 "MAR08204" "DPCOAPPe" "" "" "" "" "MNXR97763" "" "" "DPCOAPPe" "DPCOAPPe" "" "" "" 0 "MAR08218" "DSREDUCr" "" "" "" "" "" "" "" "DSREDUCr" "DSREDUCr" "" "" "" 0 @@ -9757,7 +9730,6 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR09946" "" "" "" "" "" "" "" "" "XOLEST204CEH" "XOLEST204CEH" "" "" "" 0 "MAR09947" "XOLEST226CEH" "" "" "" "" "" "" "" "XOLEST226CEH" "XOLEST226CEH" "" "" "" 0 "MAR09948" "CE4843HYDc" "" "" "" "" "" "" "" "CE4843HYDc" "CE4843HYDc" "" "" "" 0 -"MAR09949" "FACOAE60" "" "" "" "" "MNXR99139" "" "" "HXCOAc" "HXCOAc" "" "" "" 0 "MAR09950" "TETDECA511ACc" "" "" "" "" "" "" "" "TETDECA511ACc" "TETDECA511ACc" "" "" "" 0 "MAR09951" "GPDDACHOL" "" "" "" "" "" "" "" "GPDDACHOL" "GPDDACHOL" "" "" "" 0 "MAR09952" "ACLYSHYc" "" "" "" "" "" "" "" "ACLYSHYc" "ACLYSHYc" "" "" "" 0 @@ -10981,8 +10953,6 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR11289" "PHEACGLYtm" "" "" "" "" "MNXR157011" "" "" "PHEACGLYtm" "PHEACGLYtm" "" "" "" 0 "MAR11290" "HXAt1" "" "" "" "" "" "" "" "HXAt1" "HXAt1" "" "" "" 0 "MAR11291" "HXAt2" "" "" "" "" "" "" "" "HXAt2" "HXAt2" "" "" "" 0 -"MAR11292" "HXAt3" "" "" "" "" "" "" "" "HXAt3" "HXAt3" "" "" "" 0 -"MAR11293" "EX_hxa_e" "" "" "" "" "MNXR98664" "" "" "EX_hxa[e]" "EX_hxa[e]" "" "" "" 0 "MAR11294" "TTDCEAc" "" "" "" "" "" "" "" "TTDCEAc" "TTDCEAc" "" "" "" 0 "MAR11295" "PACCOALm" "" "" "" "" "" "" "" "PACCOALm" "PACCOALm" "" "" "" 0 "MAR11296" "PACALDtm" "" "" "" "" "MNXR102312" "" "" "PACALDtm" "PACALDtm" "" "" "" 0 @@ -12863,7 +12833,6 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR20009" "" "" "" "" "" "MNXR133773" "" "" "" "" "RHEA:60660" "" "" 0 "MAR20010" "" "" "" "" "" "MNXR133773" "" "" "" "" "RHEA:60660" "" "" 0 "MAR20011" "HMR_6647;RADH;R_HMR_6647;R_RADH" "" "" "" "R02123" "MNXR146215" "" "" "" "" "RHEA:42080" "" "" 0 -"MAR20012" "HMR_6647;RADH;R_HMR_6647;R_RADH" "" "" "" "R02123" "MNXR146215" "" "" "" "" "RHEA:42080" "" "" 0 "MAR20013" "" "" "" "" "R03225" "MNXR108031" "" "" "" "" "RHEA:23048" "" "" 0 "MAR20016" "ALDD16;R_ALDD16" "" "" "" "R01704" "MNXR95739" "" "" "" "" "RHEA:33739" "" "" 0 "MAR20017" "ALDD8;R_ALDD8" "" "" "" "" "MNXR95760" "" "" "" "" "RHEA:44100" "" "" 0 @@ -12932,7 +12901,6 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR20086" "" "" "" "" "" "MNXR168657" "" "" "" "" "RHEA:45372" "" "" 0 "MAR20087" "" "" "" "" "" "MNXR168656" "" "" "" "" "RHEA:45368" "" "" 0 "MAR20088" "" "" "" "" "" "MNXR168656" "" "" "" "" "RHEA:45368" "" "" 0 -"MAR20089" "" "" "" "" "R02701" "MNXR151808" "" "" "" "" "RHEA:18533" "" "" 0 "MAR20090" "HEMEOS;HEMEOS_1;HEMEOSm;HEMEOSm_1;R_HEMEOS;R_HEMEOS_1;R_HEMEOSm;R_HEMEOSm_1" "" "" "" "R07411" "MNXR115959" "" "" "" "" "RHEA:28070" "" "" 0 "MAR20091" "HEMEOS;HEMEOS_1;HEMEOSm;HEMEOSm_1;R_HEMEOS;R_HEMEOS_1;R_HEMEOSm;R_HEMEOSm_1" "" "" "" "R07411" "MNXR115959" "" "" "" "" "RHEA:28070" "" "" 0 "MAR20092" "HEMEOS;HEMEOS_1;HEMEOSm;HEMEOSm_1;R_HEMEOS;R_HEMEOS_1;R_HEMEOSm;R_HEMEOSm_1" "" "" "" "R07411" "MNXR115959" "" "" "" "" "RHEA:28070" "" "" 0 @@ -12958,6 +12926,64 @@ rxns rxnBiGGID rxnEHMNID rxnHMR2ID rxnHepatoNET1ID rxnKEGGID rxnMetaNetXID rxnRE "MAR20112" "" "" "" "" "R04385" "MNXR96330" "" "" "" "" "" "RHEA:13501" "" 0 "MAR20113" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 "MAR20114" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20115" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20116" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20117" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20118" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20119" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20120" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20121" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20122" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20123" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20124" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20125" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20126" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20127" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20128" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20129" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20130" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20131" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20132" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20133" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20134" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20135" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20136" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20137" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20138" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20139" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20140" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20141" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20142" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20143" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20144" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20145" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20146" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20147" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20148" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20149" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20150" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20151" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20152" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20153" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20154" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20155" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20156" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20157" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20158" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20159" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20160" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20161" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20162" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20163" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20164" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20165" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20166" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20167" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20168" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 +"MAR20169" "" "" "" "" "" "" "" "" "" "" "RHEA:40112" "RHEA:40111" "" 0 +"MAR20170" "" "" "" "" "" "" "" "" "" "" "RHEA:30144" "RHEA:30143" "" 0 +"MAR20171" "" "" "" "" "" "" "" "" "" "" "RHEA:40060" "RHEA:40059" "" 0 +"MAR20172" "" "" "" "" "" "" "" "" "" "" "" "" "" 0 "MAR15001" "" "" "" "" "R01465" "MNXR103402" "R-HSA-6798667" "" "" "" "" "" "" 0 "MAR15002" "" "" "" "" "R04531" "MNXR115091" "" "" "" "" "" "" "" 0 "MAR15003" "" "" "" "" "R06171" "MNXR104834" "" "" "" "" "" "" "" 0 diff --git a/version.txt b/version.txt index dc1e644..27f9cd3 100644 --- a/version.txt +++ b/version.txt @@ -1 +1 @@ -1.6.0 +1.8.0