Data and scripts for the iMotif stability predictions in a restricted C/T space of possible sequences. See the README files within the subfolders for further details on the performed calculations.
The usage of the code should be accompanied with the following citations:
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Liezel Tamon and Aleksandr B. Sahakyan, http://github.com/SahakyanLab/iMotif_dev, 2020.
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Cheng M., Qiu D., Tamon L., Istvankova E., Viskova P., Amrane S., Guedin A., Chen J., Lacroix L., Huangxian J., Trantirek L., Sahakyan A. B., Zhou J., Mergny J.-L. "Thermal and pH Stabilities of i-DNA: Confronting in vitro Experiments with Models and In-Cell NMR Data", Angew. Chem. Int. Ed., 60, 10286-10294, 2021. http://doi.org/10.1002/anie.202016801
The use of the Optimus functions should be cited as:
- Nicholas Andre G. Johnson, Liezel Tamon, Xin Liu and Aleksandr B. Sahakyan, http://github.com/SahakyanLab/Optimus/, 2018, "General purpose adaptive optimisation engine in R", in prep.
LICENSE: the code component of this repository is released under the GPLv3 license. For the permissions on the experimental dataset, see the correspondence address in the Cheng M et al. publication.